Utrn (utrophin) - Rat Genome Database

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Gene: Utrn (utrophin) Chinchilla lanigera
Analyze
Symbol: Utrn
Name: utrophin
RGD ID: 8735492
Description: ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); integrin binding (ortholog); INVOLVED IN neuromuscular junction development (ortholog); positive regulation of cell-matrix adhesion (ortholog); response to denervation involved in regulation of muscle adaptation (ortholog); ASSOCIATED WITH Duchenne muscular dystrophy (ortholog); genetic disease (ortholog); ovarian cancer (ortholog); FOUND IN contractile ring (ortholog); cortical actin cytoskeleton (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543615,730,020 - 16,231,919 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543615,730,416 - 16,237,379 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Utrn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543615,730,020 - 16,231,919 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543615,730,416 - 16,237,379 (-)NCBIChiLan1.0ChiLan1.0
UTRN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386144,285,335 - 144,853,034 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6144,285,335 - 144,853,034 (+)EnsemblGRCh38hg38GRCh38
GRCh376144,606,471 - 145,174,170 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366144,654,566 - 145,215,863 (+)NCBINCBI36Build 36hg18NCBI36
Build 346144,654,657 - 145,209,657NCBI
Celera6145,353,235 - 145,914,469 (+)NCBICelera
Cytogenetic Map6q24.2NCBI
HuRef6142,176,382 - 142,737,622 (+)NCBIHuRef
CHM1_16144,875,601 - 145,437,493 (+)NCBICHM1_1
T2T-CHM13v2.06145,477,963 - 146,045,651 (+)NCBIT2T-CHM13v2.0
Utrn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391012,257,931 - 12,745,632 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1012,257,932 - 12,745,109 (-)EnsemblGRCm39 Ensembl
GRCm381012,382,187 - 12,869,888 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1012,382,188 - 12,869,365 (-)EnsemblGRCm38mm10GRCm38
MGSCv371012,101,986 - 12,581,533 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361012,073,568 - 12,551,836 (-)NCBIMGSCv36mm8
Celera1012,282,524 - 12,766,578 (-)NCBICelera
Cytogenetic Map10A1NCBI
cM Map103.77NCBI
Utrn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr818,541,061 - 9,044,487 (-)NCBIGRCr8
mRatBN7.216,720,854 - 7,224,313 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl16,722,594 - 7,224,313 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx16,424,644 - 6,925,694 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0112,423,666 - 12,924,754 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.016,706,883 - 7,207,935 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.016,451,809 - 6,970,040 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl16,451,810 - 6,970,040 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.018,097,013 - 8,608,996 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.417,099,840 - 7,614,980 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.117,099,839 - 7,614,980 (-)NCBI
Celera15,228,645 - 5,725,909 (-)NCBICelera
RH 3.4 Map1104.42RGD
Cytogenetic Map1p13NCBI
UTRN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25164,274,877 - 164,842,973 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16162,169,685 - 162,737,303 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06142,069,139 - 142,636,507 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16146,786,654 - 147,353,226 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6146,793,153 - 147,351,210 (+)Ensemblpanpan1.1panPan2
UTRN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1135,727,531 - 36,225,533 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl135,677,814 - 36,224,065 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha136,627,086 - 37,115,507 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0135,906,556 - 36,401,715 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl135,845,084 - 36,401,052 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1135,775,436 - 36,264,006 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0135,651,671 - 36,139,451 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0135,969,567 - 36,458,179 (+)NCBIUU_Cfam_GSD_1.0
Utrn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946130,636,043 - 131,145,229 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366251,489,696 - 1,894,813 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366251,490,327 - 1,999,428 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UTRN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl120,514,260 - 21,048,484 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1120,514,264 - 21,047,927 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2122,999,397 - 23,103,391 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UTRN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11328,354,810 - 28,949,508 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1328,354,588 - 28,944,119 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040564,242 - 1,085,338 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Utrn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247539,554,240 - 9,984,058 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247539,548,914 - 10,090,635 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000020749   ⟹   ENSCLAP00000020551
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543615,730,020 - 16,231,919 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000020750   ⟹   ENSCLAP00000020552
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543615,730,020 - 16,231,803 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000020751   ⟹   ENSCLAP00000020553
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543615,730,020 - 16,180,751 (-)Ensembl
RefSeq Acc Id: XM_005389231   ⟹   XP_005389288
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543615,730,416 - 16,181,282 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005389232   ⟹   XP_005389289
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543615,730,416 - 16,237,379 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005389233   ⟹   XP_005389290
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543615,730,416 - 16,181,283 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005389234   ⟹   XP_005389291
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543615,730,416 - 16,195,602 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005389237   ⟹   XP_005389294
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543615,730,416 - 15,890,651 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005389289   ⟸   XM_005389232
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VU31 (UniProtKB/TrEMBL),   A0A8C2W1H3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005389291   ⟸   XM_005389234
- Peptide Label: isoform X4
- UniProtKB: A0A8C2W1H3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005389290   ⟸   XM_005389233
- Peptide Label: isoform X3
- UniProtKB: A0A8C2W1H3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005389288   ⟸   XM_005389231
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VW53 (UniProtKB/TrEMBL),   A0A8C2W1H3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005389294   ⟸   XM_005389237
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSCLAP00000020551   ⟸   ENSCLAT00000020749
RefSeq Acc Id: ENSCLAP00000020553   ⟸   ENSCLAT00000020751
RefSeq Acc Id: ENSCLAP00000020552   ⟸   ENSCLAT00000020750
Protein Domains
Calponin-homology (CH)   WW   ZZ-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014075 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020749 ENTREZGENE
  ENSCLAT00000020749.1 UniProtKB/TrEMBL
  ENSCLAT00000020750.1 UniProtKB/TrEMBL
  ENSCLAT00000020751 ENTREZGENE
  ENSCLAT00000020751.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  1.20.58.60 UniProtKB/TrEMBL
  2.20.70.10 UniProtKB/TrEMBL
  3.30.60.90 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro Actinin_actin-bd_CS UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  Dystrophin/utrophin UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF-hand_dom_typ1 UniProtKB/TrEMBL
  EF-hand_dom_typ2 UniProtKB/TrEMBL
  Spectrin/alpha-actinin UniProtKB/TrEMBL
  Spectrin_repeat UniProtKB/TrEMBL
  WW_dom UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
  Znf_ZZ UniProtKB/TrEMBL
  Znf_ZZ_sf UniProtKB/TrEMBL
NCBI Gene Utrn ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE KCMF1 UniProtKB/TrEMBL
  UTROPHIN UniProtKB/TrEMBL
Pfam EF-hand_2 UniProtKB/TrEMBL
  EF-hand_3 UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
  PF00569 UniProtKB/TrEMBL
  Spectrin UniProtKB/TrEMBL
PIRSF Dystrophin/utrophin UniProtKB/TrEMBL
PROSITE ACTININ_1 UniProtKB/TrEMBL
  ACTININ_2 UniProtKB/TrEMBL
  PS50021 UniProtKB/TrEMBL
  WW_DOMAIN_1 UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
  ZF_ZZ_1 UniProtKB/TrEMBL
  ZF_ZZ_2 UniProtKB/TrEMBL
SMART SM00033 UniProtKB/TrEMBL
  SM00456 UniProtKB/TrEMBL
  SPEC UniProtKB/TrEMBL
  ZnF_ZZ UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  Spectrin repeat UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF47576 UniProtKB/TrEMBL
  SSF51045 UniProtKB/TrEMBL
UniProt A0A8C2VU31 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VW53 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2W1H3 ENTREZGENE, UniProtKB/TrEMBL