Unc5a (unc-5 netrin receptor A) - Rat Genome Database

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Gene: Unc5a (unc-5 netrin receptor A) Chinchilla lanigera
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Symbol: Unc5a
Name: unc-5 netrin receptor A
RGD ID: 8717453
Description: ENCODES a protein that exhibits netrin receptor activity (ortholog); INVOLVED IN anterior/posterior axon guidance (ortholog); axon guidance (ortholog); netrin-activated signaling pathway (ortholog); ASSOCIATED WITH Chromosome 5, Trisomy 5q (ortholog); Ehlers-Danlos syndrome dermatosparaxis type (ortholog); Ehlers-Danlos syndrome spondylodysplastic type 2 (ortholog); FOUND IN neuron projection membrane (ortholog); neuronal cell body membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: netrin receptor UNC5A; unc-5 homolog A
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540829,071,792 - 29,132,037 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540829,071,812 - 29,132,744 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Unc5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540829,071,792 - 29,132,037 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540829,071,812 - 29,132,744 (+)NCBIChiLan1.0ChiLan1.0
UNC5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385176,810,559 - 176,880,898 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5176,810,519 - 176,880,898 (+)EnsemblGRCh38hg38GRCh38
GRCh375176,237,560 - 176,307,899 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365176,170,166 - 176,240,505 (+)NCBINCBI36Build 36hg18NCBI36
Celera5172,194,323 - 172,263,415 (-)NCBICelera
Cytogenetic Map5q35.2NCBI
HuRef5171,160,941 - 171,230,624 (+)NCBIHuRef
CHM1_15175,669,959 - 175,740,107 (+)NCBICHM1_1
T2T-CHM13v2.05177,357,147 - 177,426,724 (+)NCBIT2T-CHM13v2.0
Unc5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391355,090,545 - 55,153,831 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1355,097,224 - 55,153,831 (+)EnsemblGRCm39 Ensembl
GRCm381354,945,151 - 55,006,018 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1354,949,411 - 55,006,018 (+)EnsemblGRCm38mm10GRCm38
MGSCv371355,050,793 - 55,107,379 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361354,959,054 - 55,015,640 (+)NCBIMGSCv36mm8
Celera1356,010,504 - 56,066,946 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1329.8NCBI
Unc5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8179,620,005 - 9,675,794 (-)NCBIGRCr8
mRatBN7.2179,614,841 - 9,670,558 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,614,838 - 9,670,526 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx179,633,297 - 9,687,731 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01711,162,362 - 11,216,761 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0179,629,702 - 9,684,134 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01710,152,949 - 10,208,599 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1710,153,994 - 10,208,360 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01712,262,674 - 12,317,433 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41715,670,148 - 15,724,907 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11715,670,147 - 15,724,907 (-)NCBI
Celera179,693,876 - 9,708,262 (-)NCBICelera
Cytogenetic Map17p14NCBI
UNC5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24171,892,836 - 171,964,196 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15170,032,382 - 170,103,735 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05172,110,396 - 172,181,839 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15179,170,309 - 179,248,377 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5179,181,251 - 179,248,377 (+)Ensemblpanpan1.1panPan2
UNC5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1436,489,583 - 36,551,743 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl436,490,578 - 36,551,935 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha436,455,993 - 36,517,945 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0436,855,044 - 36,917,014 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl436,855,085 - 36,917,172 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1436,681,133 - 36,743,097 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0436,868,980 - 36,930,921 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0437,377,075 - 37,439,029 (-)NCBIUU_Cfam_GSD_1.0
Unc5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213122,035,589 - 122,097,770 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365971,060,496 - 1,125,045 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365971,060,496 - 1,122,832 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl281,060,803 - 81,126,196 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1281,061,096 - 81,126,191 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2282,669,034 - 82,733,793 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UNC5A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12378,819,521 - 78,888,116 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2378,871,865 - 78,890,665 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660759,976,323 - 10,050,122 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc5a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473313,262,271 - 13,322,673 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473313,262,271 - 13,322,649 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000020347   ⟹   ENSCLAP00000020152
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540829,071,792 - 29,131,873 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020348   ⟹   ENSCLAP00000020153
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540829,071,792 - 29,131,830 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000020349   ⟹   ENSCLAP00000020154
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540829,130,216 - 29,132,037 (+)Ensembl
RefSeq Acc Id: XM_005376402   ⟹   XP_005376459
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540829,071,812 - 29,132,744 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005376404   ⟹   XP_005376461
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540829,071,814 - 29,132,744 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005376405   ⟹   XP_005376462
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540829,071,814 - 29,131,830 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005376459 (Get FASTA)   NCBI Sequence Viewer  
  XP_005376461 (Get FASTA)   NCBI Sequence Viewer  
  XP_005376462 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000020152
  ENSCLAP00000020152.1
  ENSCLAP00000020153
  ENSCLAP00000020153.1
  ENSCLAP00000020154.1
RefSeq Acc Id: XP_005376462   ⟸   XM_005376405
- Peptide Label: isoform X3
- UniProtKB: A0A8C2YSJ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005376459   ⟸   XM_005376402
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VT64 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005376461   ⟸   XM_005376404
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000020152   ⟸   ENSCLAT00000020347
RefSeq Acc Id: ENSCLAP00000020153   ⟸   ENSCLAT00000020348
RefSeq Acc Id: ENSCLAP00000020154   ⟸   ENSCLAT00000020349
Protein Domains
Ig-like   UPA   ZU5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013808 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020347 ENTREZGENE
  ENSCLAT00000020347.1 UniProtKB/TrEMBL
  ENSCLAT00000020348 ENTREZGENE
  ENSCLAT00000020348.1 UniProtKB/TrEMBL
  ENSCLAT00000020349.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  2.20.100.10 UniProtKB/TrEMBL
  2.60.220.30 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
InterPro DEATH-like_dom_sf UniProtKB/TrEMBL
  Death_domain UniProtKB/TrEMBL
  Death_UNC5A UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
  UNC5 UniProtKB/TrEMBL
  UPA UniProtKB/TrEMBL
  ZU5_dom UniProtKB/TrEMBL
NCBI Gene Unc5a ENTREZGENE
PANTHER NETRIN RECEPTOR UNC5A UniProtKB/TrEMBL
  PTHR12582 UniProtKB/TrEMBL
Pfam Death UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
  UPA UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
PRINTS TSP1REPEAT UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
SMART DEATH UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF82895 UniProtKB/TrEMBL
UniProt A0A8C2VT64 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YSJ3_CHILA UniProtKB/TrEMBL
  A0A8C2YSJ6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Unc5a  unc-5 netrin receptor A    unc-5 homolog A (C. elegans)  Symbol and/or name change 5135510 APPROVED