Frrs1 (ferric chelate reductase 1) - Rat Genome Database

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Gene: Frrs1 (ferric chelate reductase 1) Chinchilla lanigera
Analyze
Symbol: Frrs1
Name: ferric chelate reductase 1
RGD ID: 8715918
Description: ENCODES a protein that exhibits oxidoreductase activity, acting on metal ions (ortholog); INVOLVED IN intracellular iron ion homeostasis (ortholog); ASSOCIATED WITH COVID-19 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ferric-chelate reductase 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554354,527,309 - 4,578,147 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554354,531,279 - 4,578,146 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Frrs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554354,527,309 - 4,578,147 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554354,531,279 - 4,578,146 (-)NCBIChiLan1.0ChiLan1.0
FRRS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38199,703,970 - 99,766,635 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl199,703,970 - 99,766,635 (-)EnsemblGRCh38hg38GRCh38
GRCh371100,169,526 - 100,232,191 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,946,847 - 100,003,937 (-)NCBINCBI36Build 36hg18NCBI36
Celera198,429,137 - 98,486,225 (-)NCBICelera
Cytogenetic Map1p21.2NCBI
HuRef198,296,421 - 98,353,509 (-)NCBIHuRef
CHM1_11100,290,568 - 100,347,637 (-)NCBICHM1_1
T2T-CHM13v2.0199,552,107 - 99,614,760 (-)NCBIT2T-CHM13v2.0
Frrs1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393116,653,212 - 116,701,363 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3116,653,113 - 116,701,826 (+)EnsemblGRCm39 Ensembl
GRCm383116,859,567 - 116,907,714 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3116,859,464 - 116,908,177 (+)EnsemblGRCm38mm10GRCm38
MGSCv373116,562,485 - 116,606,668 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363116,853,696 - 116,895,645 (+)NCBIMGSCv36mm8
Celera3123,270,351 - 123,322,896 (+)NCBICelera
Celera3116,394,336 - 116,397,499 (+)NCBICelera
Cytogenetic Map3G1NCBI
cM Map350.49NCBI
Frrs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82207,505,786 - 207,566,376 (+)NCBIGRCr8
mRatBN7.22204,820,898 - 204,881,487 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2204,823,025 - 204,895,540 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2212,477,677 - 212,534,848 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02210,394,758 - 210,453,391 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02205,211,835 - 205,270,461 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02220,415,568 - 220,469,559 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2220,432,037 - 220,468,859 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02238,476,100 - 238,531,802 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42213,124,526 - 213,162,441 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12213,004,139 - 213,124,710 (+)NCBI
Celera2197,310,928 - 197,365,310 (+)NCBICelera
Cytogenetic Map2q42NCBI
FRRS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21127,262,355 - 127,321,468 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11126,435,405 - 126,481,920 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01102,364,390 - 102,423,252 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11101,083,973 - 101,142,575 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1101,083,973 - 101,124,865 (-)Ensemblpanpan1.1panPan2
FRRS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1650,169,518 - 50,215,170 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl650,111,718 - 50,215,177 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha652,847,340 - 52,892,963 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0650,523,406 - 50,567,342 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl650,532,829 - 50,567,349 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1650,216,469 - 50,261,862 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0650,194,824 - 50,240,477 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0650,627,460 - 50,673,138 (+)NCBIUU_Cfam_GSD_1.0
Frrs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058108,828,994 - 108,858,177 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493653789,830 - 116,048 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493653789,844 - 116,512 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRRS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4118,269,156 - 118,370,773 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14118,269,141 - 118,383,647 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24129,893,645 - 129,929,941 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FRRS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12033,584,933 - 33,627,279 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2033,586,115 - 33,625,997 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603824,429,143 - 24,495,850 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Frrs1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248572,518,065 - 2,562,172 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248572,518,132 - 2,572,759 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000008259   ⟹   ENSCLAP00000008133
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554354,527,309 - 4,578,147 (-)Ensembl
RefSeq Acc Id: XM_005388788   ⟹   XP_005388845
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554354,531,279 - 4,578,146 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005388845 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000008133
  ENSCLAP00000008133.1
Reference Protein Sequences
RefSeq Acc Id: XP_005388845   ⟸   XM_005388788
- UniProtKB: A0A8C2UZP9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000008133   ⟸   ENSCLAT00000008259
Protein Domains
Cytochrome b561   DOMON   Reelin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005704 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000008259 ENTREZGENE
  ENSCLAT00000008259.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1770 UniProtKB/TrEMBL
  2.60.40.4060 UniProtKB/TrEMBL
InterPro Cyt_b561/ferric_Rdtase_TM UniProtKB/TrEMBL
  DOMON_domain UniProtKB/TrEMBL
  Reeler_dom UniProtKB/TrEMBL
  Reeler_sf UniProtKB/TrEMBL
NCBI Gene Frrs1 ENTREZGENE
PANTHER CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE UniProtKB/TrEMBL
  FERRIC-CHELATE REDUCTASE 1 UniProtKB/TrEMBL
Pfam DOMON UniProtKB/TrEMBL
  Reeler UniProtKB/TrEMBL
PROSITE CYTOCHROME_B561 UniProtKB/TrEMBL
  DOMON UniProtKB/TrEMBL
  REELIN UniProtKB/TrEMBL
SMART B561 UniProtKB/TrEMBL
  DoH UniProtKB/TrEMBL
UniProt A0A8C2UZP9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Frrs1  ferric chelate reductase 1    ferric-chelate reductase 1  Symbol and/or name change 5135510 APPROVED