FRRS1 (ferric chelate reductase 1)

Gene: FRRS1 (ferric chelate reductase 1) Canis lupus familiaris

Analyze

Symbol:

FRRS1

Name:

ferric chelate reductase 1

RGD ID:

12145051

Description:

ENCODES a protein that exhibits metal ion binding (inferred); oxidoreductase activity, acting on metal ions (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ferric-chelate reductase 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FRRS1 (ferric chelate reductase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):	Frrs1 (ferric-chelate reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Frrs1 (ferric-chelate reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Frrs1 (ferric chelate reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FRRS1 (ferric chelate reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Frrs1 (ferric chelate reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FRRS1 (ferric chelate reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FRRS1 (ferric chelate reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Frrs1 (ferric chelate reductase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	50,169,518 - 50,215,170 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	50,111,718 - 50,215,177 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	52,847,340 - 52,892,963 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	50,523,406 - 50,567,342 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	50,532,829 - 50,567,349 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	50,216,469 - 50,261,862 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	50,194,824 - 50,240,477 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	50,627,460 - 50,673,138 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular iron ion homeostasis (IEA)

Cellular Component

membrane (IEA)

Molecular Function

metal ion binding (IEA)

oxidoreductase activity, acting on metal ions (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

FRRS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	50,169,518 - 50,215,170 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	50,111,718 - 50,215,177 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	52,847,340 - 52,892,963 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	50,523,406 - 50,567,342 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	50,532,829 - 50,567,349 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	50,216,469 - 50,261,862 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	50,194,824 - 50,240,477 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	50,627,460 - 50,673,138 (+)	NCBI		UU_Cfam_GSD_1.0

FRRS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	99,703,970 - 99,766,635 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	99,703,970 - 99,766,635 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	100,169,526 - 100,232,191 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	99,946,847 - 100,003,937 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	98,429,137 - 98,486,225 (-)	NCBI		Celera
Cytogenetic Map	1	p21.2	NCBI
HuRef	1	98,296,421 - 98,353,509 (-)	NCBI		HuRef
CHM1_1	1	100,290,568 - 100,347,637 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	99,552,107 - 99,614,760 (-)	NCBI		T2T-CHM13v2.0

Frrs1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	116,653,212 - 116,701,363 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	116,653,113 - 116,701,826 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	116,859,567 - 116,907,714 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	116,859,464 - 116,908,177 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	116,562,485 - 116,606,668 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	116,853,696 - 116,895,645 (+)	NCBI		MGSCv36	mm8
Celera	3	123,270,351 - 123,322,896 (+)	NCBI		Celera
Celera	3	116,394,336 - 116,397,499 (+)	NCBI		Celera
Cytogenetic Map	3	G1	NCBI
cM Map	3	50.49	NCBI

Frrs1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	207,505,786 - 207,566,376 (+)	NCBI		GRCr8
mRatBN7.2	2	204,820,898 - 204,881,487 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	204,823,025 - 204,895,540 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	212,477,677 - 212,534,848 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	210,394,758 - 210,453,391 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	205,211,835 - 205,270,461 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	220,415,568 - 220,469,559 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	220,432,037 - 220,468,859 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	238,476,100 - 238,531,802 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	213,124,526 - 213,162,441 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	213,004,139 - 213,124,710 (+)	NCBI
Celera	2	197,310,928 - 197,365,310 (+)	NCBI		Celera
Cytogenetic Map	2	q42	NCBI

Frrs1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	4,527,309 - 4,578,147 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955435	4,531,279 - 4,578,146 (-)	NCBI	ChiLan1.0	ChiLan1.0

FRRS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	127,262,355 - 127,321,468 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	126,435,405 - 126,481,920 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	102,364,390 - 102,423,252 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	101,083,973 - 101,142,575 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	101,083,973 - 101,124,865 (-)	Ensembl	panpan1.1		panPan2

Frrs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	108,828,994 - 108,858,177 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936537	89,830 - 116,048 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936537	89,844 - 116,512 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FRRS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	118,269,156 - 118,370,773 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	118,269,141 - 118,383,647 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	129,893,645 - 129,929,941 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FRRS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	33,584,933 - 33,627,279 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	33,586,115 - 33,625,997 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	24,429,143 - 24,495,850 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Frrs1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624857	2,518,065 - 2,562,172 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624857	2,518,132 - 2,572,759 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in FRRS1
678 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium							4
Low	4	5	17	6	5	6	2		7		10	6
Below cutoff	1		5		1			6	5	8

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005621873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014114807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038479953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038479954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038541229	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038541230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038605381	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038605382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038670016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000031906 ⟹ ENSCAFP00000029708

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	50,171,102 - 50,215,177 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000060872 ⟹ ENSCAFP00000065381

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	50,111,718 - 50,215,177 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000062458 ⟹ ENSCAFP00000055924

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	50,180,682 - 50,215,177 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000079079 ⟹ ENSCAFP00000048387

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	50,116,494 - 50,215,177 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845024544 ⟹ ENSCAFP00845019303

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	6	50,532,829 - 50,567,349 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845024580 ⟹ ENSCAFP00845019336

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	6	50,532,829 - 50,567,349 (+)	Ensembl

RefSeq Acc Id:

XM_005621873 ⟹ XP_005621930

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	6	50,171,259 - 50,215,170 (+)	NCBI
Dog10K_Boxer_Tasha	6	52,849,068 - 52,892,963 (+)	NCBI

Sequence:

show sequence

GGAGCCCAGGATCACTATTTGAGCCAAAGGCAGATGCTCAACCACTGAGCCACACAGATGGCAG
TTCTTGGATTTACCCTTGCTACCTTCCTACTTGTGCTGTACGTTAGTTCTGTGGCTAATTATCC
CAATGGAAAAGTAGGAAGGTCATGCCATGGAATGGTTCCTGAACATGGTCATACTGCACACTCT
GATCCTGTTCACAACATTTCAGTGAGTCAGATGACGTTCAGACGAGGAGATCAGATTGAAGTAA
CCTTGTCAGGGCCACCATTTAGAGGCTTTCTCTTAGAAGCACGGAATGCTGAGGATTTGAGTGG
CCCTCCTATTGGCTCCTTCACATTGATTGACAGTCAAGTGTCACAGCTTCTGACCTGTGAAGAT
GTACAGGGATATGCTGTGAGTCACACGAGTCCATCCAAGAAAACAAAAGTTAAAGTCTACTGGA
ATGCTCTAAGCAATGCTCCGAATAATGTAAAGTTTCTAGTCACAGTTGTTGAGAAGTATAAAAC
CTACTGGGTGAAGATTCCTGGTCCTATAATTTCACAACCAAATGCACTGCCTTTTACAACGCCT
GAAGCTACAATAGCCCCTTTGTCGACATTACCTCCGGTCTCCCATTTAAGCAAATCATTCAGCG
CTTCAGATTGTGGGAACAAGAAGTTCTGCATTCGGAGTCCTTTGAACTGTGACCCAGAGAAGGA
GCATGCCTGTTTCTTCTTGTCCTTTGCTCGAGATGACCAGTCAGTGGTGGTTGAAATGAGTGGT
CCCAGTCAAGGCTATTTATCCTTTGCATTTTCTCACGACAGATGGATGGGTGATGATGATGCTT
ATTTGTGTATTCGTGAAGATCAGACCGTGCACATACAACCTTCTCACTTGACGGGGCGAAGTCA
CCCTGTGATGGACTCTAGGGGTGCTCTTGAGGATATGGCTTGGAGGCTGGCGGATGGTGTTATA
CAGTGTTCTTTCAGAAGAAACATTACCCTTCCTGGGGTTAAAAATAGATTTGATCTAAACACAA
GCTACTACATATTTCTAGCAGATGGTGCAGCTGACAATGGTCGAATTTATAAGCATTCGCGGCA
ACCTTTGATTACATATGAAAAACATAATGTGACAGGCTATCCAAAGAACGTGGGAGGATCCCGT
TCTTTATTCCTTCTGAAGACACATGGTGCCTTAATGTTTGTGGCCTGGATGACTACCGTGAGCA
TAGGTGTGCTCATTGCTCGGTTCTTCAAATCTGTTTGGTCAAAGGCCTTCCTTGGTCAAGCAGC
TTGGTTTCAGGTGCATCGGATGCTTATGCTCACTACGACTGCCCTCACCTGCATTGCTTTTGTT
CTGCCTTTTATTTACAGAGGAGGCTGGAGTTCGTATGCAGGTTATCACCCATACCTTGGTTGTA
TAGTGATGATTTTAGCAGTTCTTCAGCCTCTTTTGGCAGCCTTCAGGCCACCTTTACATGACCC
AAGGAGGCACATTTTTAACTGGACTCATTGGAGTATGGGCACAGCTGCTAGAATAATAGCAGTG
GCAGCAATGTTCCTGGGAATGGATTTACCAGGACTGGATCTTCCTGGCCCATGGAAAACCTATG
TAATGATTGGATTTGTAGCCTGGCATGTTGGGACGGAGATTCTTTTGGAGATACATGCTTACCG
ACTTTCTCGAAAAGTTGAAATATTGGATGATGCTAGAATTCAGATCCTTCAGTCATGCACTGTA
GCTGAAGCAGAAGGTCATGCTTTTAAAAAGGTGGTGTTTGCAGTTTATATCTGCGGGAATGTGA
CTTTTCTCATCATATTCTTATCTGCAATCAACCGGCTGTGAGCAAGCAAAGACCTTGGCTATGC
AGACCACATGATAATTATCATTAAGCCAAAGATACTTGAAGCCTATACTGACTGCCTGAAGCAT
ATTCATGAATTCTGAATTGGAAGACCAGGTCTTATCTGTAGAGGAATTCTGAGGTGTGGTCTTA
GAGATCAACGTTCAGAGGGTCCTATGGACTATAGAAAGGATGTCAAGACTTCATGTGTGATTCT
GAGTGTTACCAGGAAAGGCTGTACAAGAGAAATGACTCTCAAATATTTTCTATGATGAGATATA
TAGAATGCTAGCATTTGAGAAAAGAATGATTTGGAAAGACAGAAATGATGTCATTTGGATGAAA
TGGAGATTGTATTAATGTATCAAATATATTTTAGACTATAAAGGTGCTGTTTTAAAGAAAGCAT
TTATACTGGTTTACCTGAATGGTCTCTTTTAGGACTTGAGAAACTATGTTTTTCAGTTCAGTTT
TTGGGACTTTTTTTTTTTTTTTTTTTTTTTATGTCTTGTTACTTCTCTGGTAAAGGTGGAAGTG
GGACTTACTCCATTGTATTAACATTGAAATGTATTATGAATATTACAATTTCTTTCTTACTCAT
GAAATGCAAGTGTGCATCTTCTATTTAACACTGTGTTTATATGTCCAGTGACAGGGCTGAAATG
ACATTTTATATGTTAATTGTTTTGACTCTAACATTTAAGTCCTTGCTTTTGGAGATTGTAGCCT
TGCATTTCGAAAGTAATAAAATTTACTCTTGTGAATATA

hide sequence

RefSeq Acc Id:

XM_014114807 ⟹ XP_013970282

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	6	50,169,518 - 50,215,170 (+)	NCBI
Dog10K_Boxer_Tasha	6	52,847,340 - 52,892,963 (+)	NCBI

Sequence:

show sequence

TACTGGTCTTGCAAATCAAGTTTTGCTGCTTAGCTTGGGAAACGTTGCCTTCTGGTTACTGGGT
AAGCGGGCTCCACCCAGCTGCTGAAAGCAGATACAAATTGTAACAAAACCGGAAGTTGGCTAGG
CTGCCTTTGCTTCTCAAGATGGCAGTTCTTGGATTTACCCTTGCTACCTTCCTACTTGTGCTGT
ACGTTAGTTCTGTGGCTAATTATCCCAATGGAAAAGTAGGAAGGTCATGCCATGGAATGGTTCC
TGAACATGGTCATACTGCACACTCTGATCCTGTTCACAACATTTCAGTGAGTCAGATGACGTTC
AGACGAGGAGATCAGATTGAAGTAACCTTGTCAGGGCCACCATTTAGAGGCTTTCTCTTAGAAG
CACGGAATGCTGAGGATTTGAGTGGCCCTCCTATTGGCTCCTTCACATTGATTGACAGTCAAGT
GTCACAGCTTCTGACCTGTGAAGATGTACAGGGATATGCTGTGAGTCACACGAGTCCATCCAAG
AAAACAAAAGTTAAAGTCTACTGGAATGCTCTAAGCAATGCTCCGAATAATGTAAAGTTTCTAG
TCACAGTTGTTGAGAAGTATAAAACCTACTGGGTGAAGATTCCTGGTCCTATAATTTCACAACC
AAATGCACTGCCTTTTACAACGCCTGAAGCTACAATAGCCCCTTTGTCGACATTACCTCCGGTC
TCCCATTTAAGCAAATCATTCAGCGCTTCAGATTGTGGGAACAAGAAGTTCTGCATTCGGAGTC
CTTTGAACTGTGACCCAGAGAAGGAGCATGCCTGTTTCTTCTTGTCCTTTGCTCGAGATGACCA
GTCAGTGGTGGTTGAAATGAGTGGTCCCAGTCAAGGCTATTTATCCTTTGCATTTTCTCACGAC
AGATGGATGGGTGATGATGATGCTTATTTGTGTATTCGTGAAGATCAGACCGTGCACATACAAC
CTTCTCACTTGACGGGGCGAAGTCACCCTGTGATGGACTCTAGGGGTGCTCTTGAGGATATGGC
TTGGAGGCTGGCGGATGGTGTTATACAGTGTTCTTTCAGAAGAAACATTACCCTTCCTGGGGTT
AAAAATAGATTTGATCTAAACACAAGCTACTACATATTTCTAGCAGATGGTGCAGCTGACAATG
GTCGAATTTATAAGCATTCGCGGCAACCTTTGATTACATATGAAAAACATAATGTGACAGGCTA
TCCAAAGAACGTGGGAGGATCCCGTTCTTTATTCCTTCTGAAGACACATGGTGCCTTAATGTTT
GTGGCCTGGATGACTACCGTGAGCATAGGTGTGCTCATTGCTCGGTTCTTCAAATCTGTTTGGT
CAAAGGCCTTCCTTGGTCAAGCAGCTTGGTTTCAGGTGCATCGGATGCTTATGCTCACTACGAC
TGCCCTCACCTGCATTGCTTTTGTTCTGCCTTTTATTTACAGAGGAGGCTGGAGTTCGTATGCA
GGTTATCACCCATACCTTGGTTGTATAGTGATGATTTTAGCAGTTCTTCAGCCTCTTTTGGCAG
CCTTCAGGCCACCTTTACATGACCCAAGGAGGCACATTTTTAACTGGACTCATTGGAGTATGGG
CACAGCTGCTAGAATAATAGCAGTGGCAGCAATGTTCCTGGGAATGGATTTACCAGGACTGGAT
CTTCCTGGCCCATGGAAAACCTATGTAATGATTGGATTTGTAGCCTGGCATGTTGGGACGGAGA
TTCTTTTGGAGATACATGCTTACCGACTTTCTCGAAAAGTTGAAATATTGGATGATGCTAGAAT
TCAGATCCTTCAGTCATGCACTGTAGCTGAAGCAGAAGGTCATGCTTTTAAAAAGGTGGTGTTT
GCAGTTTATATCTGCGGGAATGTGACTTTTCTCATCATATTCTTATCTGCAATCAACCGGCTGT
GAGCAAGCAAAGACCTTGGCTATGCAGACCACATGATAATTATCATTAAGCCAAAGATACTTGA
AGCCTATACTGACTGCCTGAAGCATATTCATGAATTCTGAATTGGAAGACCAGGTCTTATCTGT
AGAGGAATTCTGAGGTGTGGTCTTAGAGATCAACGTTCAGAGGGTCCTATGGACTATAGAAAGG
ATGTCAAGACTTCATGTGTGATTCTGAGTGTTACCAGGAAAGGCTGTACAAGAGAAATGACTCT
CAAATATTTTCTATGATGAGATATATAGAATGCTAGCATTTGAGAAAAGAATGATTTGGAAAGA
CAGAAATGATGTCATTTGGATGAAATGGAGATTGTATTAATGTATCAAATATATTTTAGACTAT
AAAGGTGCTGTTTTAAAGAAAGCATTTATACTGGTTTACCTGAATGGTCTCTTTTAGGACTTGA
GAAACTATGTTTTTCAGTTCAGTTTTTGGGACTTTTTTTTTTTTTTTTTTTTTTTATGTCTTGT
TACTTCTCTGGTAAAGGTGGAAGTGGGACTTACTCCATTGTATTAACATTGAAATGTATTATGA
ATATTACAATTTCTTTCTTACTCATGAAATGCAAGTGTGCATCTTCTATTTAACACTGTGTTTA
TATGTCCAGTGACAGGGCTGAAATGACATTTTATATGTTAATTGTTTTGACTCTAACATTTAAG
TCCTTGCTTTTGGAGATTGTAGCCTTGCATTTCGAAAGTAATAAAATTTACTCTTGTGAATATA

hide sequence

RefSeq Acc Id:

XM_038479953 ⟹ XP_038335881

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	6	50,216,469 - 50,261,862 (+)	NCBI

RefSeq Acc Id:

XM_038479954 ⟹ XP_038335882

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	6	50,218,202 - 50,261,862 (+)	NCBI

RefSeq Acc Id:

XM_038541229 ⟹ XP_038397157

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	6	50,627,460 - 50,673,138 (+)	NCBI

RefSeq Acc Id:

XM_038541230 ⟹ XP_038397158

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	6	50,629,197 - 50,673,138 (+)	NCBI

RefSeq Acc Id:

XM_038605381 ⟹ XP_038461309

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	6	50,194,824 - 50,240,477 (+)	NCBI

RefSeq Acc Id:

XM_038605382 ⟹ XP_038461310

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	6	50,196,553 - 50,240,477 (+)	NCBI

RefSeq Acc Id:

XM_038670016 ⟹ XP_038525944

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	6	50,523,406 - 50,567,342 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005621930	(Get FASTA)	NCBI Sequence Viewer
	XP_013970282	(Get FASTA)	NCBI Sequence Viewer
	XP_038335881	(Get FASTA)	NCBI Sequence Viewer
	XP_038335882	(Get FASTA)	NCBI Sequence Viewer
	XP_038397157	(Get FASTA)	NCBI Sequence Viewer
	XP_038397158	(Get FASTA)	NCBI Sequence Viewer
	XP_038461309	(Get FASTA)	NCBI Sequence Viewer
	XP_038461310	(Get FASTA)	NCBI Sequence Viewer
	XP_038525944	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000029708.5
	ENSCAFP00000048387.2
	ENSCAFP00000055924.1
	ENSCAFP00030025738.1
	ENSCAFP00030025798.1
	ENSCAFP00030025872.1
	ENSCAFP00030025933.1
	ENSCAFP00040004064.1
	ENSCAFP00040004089.1
	ENSCAFP00040004109.1
	ENSCAFP00040004132.1
	ENSCAFP00040004155.1
	ENSCAFP00845019303
	ENSCAFP00845019303.1
	ENSCAFP00845019336.1

RefSeq Acc Id:

XP_013970282 ⟸ XM_014114807

- UniProtKB:

A0A8P0SP43 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAVLGFTLATFLLVLYVSSVANYPNGKVGRSCHGMVPEHGHTAHSDPVHNISVSQMTFRRGDQI
EVTLSGPPFRGFLLEARNAEDLSGPPIGSFTLIDSQVSQLLTCEDVQGYAVSHTSPSKKTKVKV
YWNALSNAPNNVKFLVTVVEKYKTYWVKIPGPIISQPNALPFTTPEATIAPLSTLPPVSHLSKS
FSASDCGNKKFCIRSPLNCDPEKEHACFFLSFARDDQSVVVEMSGPSQGYLSFAFSHDRWMGDD
DAYLCIREDQTVHIQPSHLTGRSHPVMDSRGALEDMAWRLADGVIQCSFRRNITLPGVKNRFDL
NTSYYIFLADGAADNGRIYKHSRQPLITYEKHNVTGYPKNVGGSRSLFLLKTHGALMFVAWMTT
VSIGVLIARFFKSVWSKAFLGQAAWFQVHRMLMLTTTALTCIAFVLPFIYRGGWSSYAGYHPYL
GCIVMILAVLQPLLAAFRPPLHDPRRHIFNWTHWSMGTAARIIAVAAMFLGMDLPGLDLPGPWK
TYVMIGFVAWHVGTEILLEIHAYRLSRKVEILDDARIQILQSCTVAEAEGHAFKKVVFAVYICG
NVTFLIIFLSAINRL

hide sequence

RefSeq Acc Id:

XP_005621930 ⟸ XM_005621873

- UniProtKB:

A0A8P0SP43 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAVLGFTLATFLLVLYVSSVANYPNGKVGRSCHGMVPEHGHTAHSDPVHNISVSQMTFRRGDQI
EVTLSGPPFRGFLLEARNAEDLSGPPIGSFTLIDSQVSQLLTCEDVQGYAVSHTSPSKKTKVKV
YWNALSNAPNNVKFLVTVVEKYKTYWVKIPGPIISQPNALPFTTPEATIAPLSTLPPVSHLSKS
FSASDCGNKKFCIRSPLNCDPEKEHACFFLSFARDDQSVVVEMSGPSQGYLSFAFSHDRWMGDD
DAYLCIREDQTVHIQPSHLTGRSHPVMDSRGALEDMAWRLADGVIQCSFRRNITLPGVKNRFDL
NTSYYIFLADGAADNGRIYKHSRQPLITYEKHNVTGYPKNVGGSRSLFLLKTHGALMFVAWMTT
VSIGVLIARFFKSVWSKAFLGQAAWFQVHRMLMLTTTALTCIAFVLPFIYRGGWSSYAGYHPYL
GCIVMILAVLQPLLAAFRPPLHDPRRHIFNWTHWSMGTAARIIAVAAMFLGMDLPGLDLPGPWK
TYVMIGFVAWHVGTEILLEIHAYRLSRKVEILDDARIQILQSCTVAEAEGHAFKKVVFAVYICG
NVTFLIIFLSAINRL

hide sequence

RefSeq Acc Id:

ENSCAFP00000065381 ⟸ ENSCAFT00000060872

RefSeq Acc Id:

ENSCAFP00000048387 ⟸ ENSCAFT00000079079

RefSeq Acc Id:

ENSCAFP00000055924 ⟸ ENSCAFT00000062458

RefSeq Acc Id:

ENSCAFP00000029708 ⟸ ENSCAFT00000031906

RefSeq Acc Id:

XP_038335881 ⟸ XM_038479953

RefSeq Acc Id:

XP_038335882 ⟸ XM_038479954

RefSeq Acc Id:

XP_038461309 ⟸ XM_038605381

RefSeq Acc Id:

XP_038461310 ⟸ XM_038605382

RefSeq Acc Id:	XP_038525944 ⟸ XM_038670016
- UniProtKB:	A0A8C0RW46 (UniProtKB/TrEMBL), A0A8I3NFF6 (UniProtKB/TrEMBL), A0A8C0KF49 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038397157 ⟸ XM_038541229
- UniProtKB:	A0A8C0KF49 (UniProtKB/TrEMBL), A0A8C0RW46 (UniProtKB/TrEMBL), A0A8I3NFF6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038397158 ⟸ XM_038541230
- UniProtKB:	A0A8C0KF49 (UniProtKB/TrEMBL), A0A8C0RW46 (UniProtKB/TrEMBL), A0A8I3NFF6 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845019303 ⟸ ENSCAFT00845024544

RefSeq Acc Id:

ENSCAFP00845019336 ⟸ ENSCAFT00845024580

Protein Domains

Cytochrome b561 DOMON Reelin

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000020052	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030016052	UniProtKB/TrEMBL
	ENSCAFG00040002480	UniProtKB/TrEMBL
	ENSCAFG00845013726	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000031906.5	UniProtKB/TrEMBL
	ENSCAFT00000062458.2	UniProtKB/TrEMBL
	ENSCAFT00000079079.2	UniProtKB/TrEMBL
	ENSCAFT00030029535.1	UniProtKB/TrEMBL
	ENSCAFT00030029608.1	UniProtKB/TrEMBL
	ENSCAFT00030029691.1	UniProtKB/TrEMBL
	ENSCAFT00030029764.1	UniProtKB/TrEMBL
	ENSCAFT00040004729.1	UniProtKB/TrEMBL
	ENSCAFT00040004766.1	UniProtKB/TrEMBL
	ENSCAFT00040004791.1	UniProtKB/TrEMBL
	ENSCAFT00040004816.1	UniProtKB/TrEMBL
	ENSCAFT00040004839.1	UniProtKB/TrEMBL
	ENSCAFT00845024544	ENTREZGENE
	ENSCAFT00845024544.1	UniProtKB/TrEMBL
	ENSCAFT00845024580.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.120.1770	UniProtKB/TrEMBL
	2.60.40.4060	UniProtKB/TrEMBL
InterPro	Cyt_b561/ferric_Rdtase_TM	UniProtKB/TrEMBL
	DOMON_domain	UniProtKB/TrEMBL
	Reeler_dom	UniProtKB/TrEMBL
	Reeler_sf	UniProtKB/TrEMBL
NCBI Gene	FRRS1	ENTREZGENE
PANTHER	CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE	UniProtKB/TrEMBL
	FERRIC-CHELATE REDUCTASE 1	UniProtKB/TrEMBL
Pfam	DOMON	UniProtKB/TrEMBL
	Reeler	UniProtKB/TrEMBL
PROSITE	CYTOCHROME_B561	UniProtKB/TrEMBL
	DOMON	UniProtKB/TrEMBL
	REELIN	UniProtKB/TrEMBL
SMART	B561	UniProtKB/TrEMBL
	DoH	UniProtKB/TrEMBL
UniProt	A0A8C0KF49	ENTREZGENE
	A0A8C0NE42_CANLF	UniProtKB/TrEMBL
	A0A8C0NE89_CANLF	UniProtKB/TrEMBL
	A0A8C0NFR3_CANLF	UniProtKB/TrEMBL
	A0A8C0PU56_CANLF	UniProtKB/TrEMBL
	A0A8C0PUW9_CANLF	UniProtKB/TrEMBL
	A0A8C0Q2Q1_CANLF	UniProtKB/TrEMBL
	A0A8C0RW46	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NFF6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3S0D1_CANLF	UniProtKB/TrEMBL
	A0A8P0SP43	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0T179_CANLF	UniProtKB/TrEMBL
	A0A8P0T824_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:40985	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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