Psme2 (proteasome (prosome, macropain) activator subunit 2 (PA28 beta)) - Rat Genome Database

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Gene: Psme2 (proteasome (prosome, macropain) activator subunit 2 (PA28 beta)) Mus musculus
Analyze
Symbol: Psme2
Name: proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
RGD ID: 736572
MGI Page MGI
Description: Contributes to endopeptidase activator activity. Acts upstream of or within antigen processing and presentation of exogenous antigen. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in several structures, including heart; hemolymphoid system; liver; lung; and pancreas. Orthologous to human PSME2 (proteasome activator subunit 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 11S regulator complex subunit beta; AA589371; activator of multicatalytic protease subunit 2; AI788882; PA2; PA28b; PA28beta; protease (prosome, macropain) 28 subunit, beta; proteasome (prosome, macropain) 28 subunit, beta; proteasome activator 28 subunit beta; proteasome activator complex subunit 2; REG-beta
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Psme2-ps1   Psme2-ps2  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,824,897 - 55,828,558 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,824,898 - 55,828,570 (-)EnsemblGRCm39 Ensembl
GRCm381455,587,440 - 55,591,101 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,587,441 - 55,591,113 (-)EnsemblGRCm38mm10GRCm38
MGSCv371456,206,277 - 56,209,938 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,541,511 - 54,545,172 (-)NCBIMGSCv36mm8
Celera1453,392,500 - 53,396,161 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3-methylcholanthrene  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
diuron  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (EXP)
ethanol  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
FR900359  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (ISO)
inulin  (EXP)
ivermectin  (ISO)
L-ascorbic acid  (EXP)
lead diacetate  (EXP)
lithium atom  (ISO)
lithium hydride  (ISO)
methimazole  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
ochratoxin A  (ISO)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
propiconazole  (ISO)
rotenone  (EXP,ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (ISO)
tamibarotene  (ISO)
tetrachloromethane  (ISO)
thalidomide  (EXP)
thioacetamide  (ISO)
tolcapone  (ISO)
triptonide  (EXP)
tungsten  (EXP)
vancomycin  (EXP)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
nucleoplasm  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Structural analysis and chromosomal localization of the mouse Psmb5 gene coding for the constitutively expressed beta-type proteasome subunit. Kohda K, etal., Immunogenetics 1997;47(1):77-87.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9162094   PMID:9218537   PMID:9287111   PMID:9590240   PMID:9914329   PMID:10047537   PMID:10222192   PMID:10349636   PMID:10567354   PMID:10591649   PMID:11042159   PMID:11076861  
PMID:11345588   PMID:11471063   PMID:11689430   PMID:12119343   PMID:12477932   PMID:14610273   PMID:15356141   PMID:15944286   PMID:16141072   PMID:16141073   PMID:16569681   PMID:18641301  
PMID:18799693   PMID:21267068   PMID:21360704   PMID:21873635   PMID:22308036   PMID:22564544   PMID:22772448   PMID:22802414   PMID:23209186   PMID:28278207   PMID:28867616   PMID:29067678  
PMID:30400847   PMID:30457570   PMID:31608052   PMID:32325033   PMID:32554809  


Genomics

Comparative Map Data
Psme2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,824,897 - 55,828,558 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,824,898 - 55,828,570 (-)EnsemblGRCm39 Ensembl
GRCm381455,587,440 - 55,591,101 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,587,441 - 55,591,113 (-)EnsemblGRCm38mm10GRCm38
MGSCv371456,206,277 - 56,209,938 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,541,511 - 54,545,172 (-)NCBIMGSCv36mm8
Celera1453,392,500 - 53,396,161 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
PSME2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,143,365 - 24,146,610 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,143,362 - 24,147,570 (-)EnsemblGRCh38hg38GRCh38
GRCh371424,612,574 - 24,615,819 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,682,414 - 23,685,695 (-)NCBINCBI36Build 36hg18NCBI36
Build 341423,682,413 - 23,685,695NCBI
Celera144,477,042 - 4,480,323 (-)NCBICelera
Cytogenetic Map14q12NCBI
HuRef144,727,638 - 4,730,919 (-)NCBIHuRef
CHM1_11424,611,243 - 24,614,524 (-)NCBICHM1_1
T2T-CHM13v2.01418,341,674 - 18,344,919 (-)NCBIT2T-CHM13v2.0
Psme2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,048,452 - 33,053,055 (-)NCBIGRCr8
mRatBN7.21529,078,495 - 29,082,794 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,078,500 - 29,082,946 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,924,197 - 30,928,500 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01532,071,403 - 32,075,706 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,313,749 - 30,318,048 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,265,552 - 34,269,851 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,265,557 - 34,269,851 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,155,747 - 38,160,046 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,722,370 - 33,726,669 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,738,074 - 33,742,369 (-)NCBI
Celera1528,654,415 - 28,658,714 (-)NCBICelera
Cytogenetic Map15p13NCBI
Psme2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540936,252,847 - 36,257,021 (+)NCBIChiLan1.0ChiLan1.0
PSME2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,497,735 - 25,501,589 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,714,227 - 24,718,201 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,919,628 - 4,922,952 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11423,043,807 - 23,047,296 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,043,807 - 23,047,296 (-)Ensemblpanpan1.1panPan2
PSME2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,137,247 - 4,141,380 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,137,247 - 4,140,706 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha84,058,934 - 4,062,482 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,247,825 - 4,251,369 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,247,825 - 4,251,981 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,938,451 - 3,941,999 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.084,000,202 - 4,003,738 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,262,361 - 4,265,901 (-)NCBIUU_Cfam_GSD_1.0
Psme2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,987,005 - 35,991,113 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722397,876 - 402,167 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722398,406 - 401,987 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSME2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,153,965 - 75,157,870 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,154,570 - 75,157,871 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,425,857 - 80,429,167 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7q12-q23NCBI
PSME2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,129,389 - 1,133,289 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,129,419 - 1,132,596 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,811,110 - 12,814,585 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psme2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,389,286 - 8,393,498 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,389,348 - 8,393,498 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Psme2
83 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1413
Count of miRNA genes:484
Interacting mature miRNAs:574
Transcripts:ENSMUST00000111378, ENSMUST00000159282, ENSMUST00000159297, ENSMUST00000159687, ENSMUST00000159845, ENSMUST00000161027, ENSMUST00000161573, ENSMUST00000161807, ENSMUST00000162496, ENSMUST00000162700
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142792195761137449Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142999699463997133Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143033525064335381Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143033525064335381Mouse
27226737Metcl12_mmetatarsal-calcaneal length 12, 10 week (mouse)143322195759437449Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143504579768785736Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143743018571430320Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4033731974337319Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
4141484Hcbip1_mhexachlorobenzene induced porphyria 1 (mouse)Not determined4733525059962593Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145393744087937440Mouse

Markers in Region
RH129915  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381455,587,466 - 55,588,058UniSTSGRCm38
GRCm381148,945,380 - 48,945,585UniSTSGRCm38
MGSCv371456,206,303 - 56,206,895UniSTSGRCm37
MGSCv371148,758,882 - 48,759,087UniSTSGRCm37
Celera1453,392,526 - 53,393,118UniSTS
Cytogenetic Map14C2-D1UniSTS
Cytogenetic Map11B1.2UniSTS
AI788882  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381455,587,897 - 55,587,991UniSTSGRCm38
MGSCv371456,206,734 - 56,206,828UniSTSGRCm37
Celera1453,392,957 - 53,393,051UniSTS
Cytogenetic Map14C2-D1UniSTS
Whitehead/MRC_RH14610.58UniSTS
RH124942  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381148,945,524 - 48,945,860UniSTSGRCm38
MGSCv371148,759,026 - 48,759,362UniSTSGRCm37
Cytogenetic Map14C2-D1UniSTS
Cytogenetic Map11B1.2UniSTS
Psme2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381455,587,840 - 55,588,071UniSTSGRCm38
MGSCv371456,206,677 - 56,206,908UniSTSGRCm37
Celera1453,392,900 - 53,393,131UniSTS
Cytogenetic Map14C2-D1UniSTS
cM Map1422.5UniSTS
MARC_4677-4678:996679594:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381455,588,475 - 55,589,335UniSTSGRCm38
GRCm381148,945,721 - 48,945,793UniSTSGRCm38
MGSCv371456,207,312 - 56,208,172UniSTSGRCm37
MGSCv371148,759,223 - 48,759,295UniSTSGRCm37
Celera1453,393,535 - 53,394,395UniSTS
Cytogenetic Map14C2-D1UniSTS
Cytogenetic Map11B1.2UniSTS
RH71322  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381148,945,405 - 48,945,575UniSTSGRCm38
MGSCv371148,758,907 - 48,759,077UniSTSGRCm37
Cytogenetic Map14C2-D1UniSTS
Cytogenetic Map11B1.2UniSTS
Psme2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14C2-D1UniSTS
Psme2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.2UniSTS
Cytogenetic Map14C2-D1UniSTS
Cytogenetic Map13B3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001029855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA216967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AA267668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB007138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB053120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC174678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF060195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB869062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU563130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY134400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY498670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA536627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U60329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000111378   ⟹   ENSMUSP00000107009
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1455,824,899 - 55,828,558 (-)Ensembl
GRCm38.p6 Ensembl1455,587,442 - 55,591,101 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159282
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1455,825,540 - 55,828,321 (-)Ensembl
GRCm38.p6 Ensembl1455,588,083 - 55,590,864 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159297
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1455,827,455 - 55,828,352 (-)Ensembl
GRCm38.p6 Ensembl1455,589,998 - 55,590,895 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159687   ⟹   ENSMUSP00000125596
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1455,825,529 - 55,828,570 (-)Ensembl
GRCm38.p6 Ensembl1455,588,072 - 55,591,113 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159845
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1455,826,774 - 55,828,405 (-)Ensembl
GRCm38.p6 Ensembl1455,589,317 - 55,590,948 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161027
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1455,825,511 - 55,827,606 (-)Ensembl
GRCm38.p6 Ensembl1455,588,054 - 55,590,149 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161573
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1455,824,904 - 55,826,061 (-)Ensembl
GRCm38.p6 Ensembl1455,587,447 - 55,588,604 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161807   ⟹   ENSMUSP00000123798
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1455,824,898 - 55,828,544 (-)Ensembl
GRCm38.p6 Ensembl1455,587,441 - 55,591,087 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162496
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1455,826,651 - 55,828,430 (-)Ensembl
GRCm38.p6 Ensembl1455,589,194 - 55,590,973 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162700
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1455,824,904 - 55,826,968 (-)Ensembl
GRCm38.p6 Ensembl1455,587,447 - 55,589,511 (-)Ensembl
RefSeq Acc Id: NM_001029855   ⟹   NP_001025026
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391455,824,897 - 55,828,558 (-)NCBI
GRCm381455,587,440 - 55,591,101 (-)NCBI
MGSCv371456,206,277 - 56,209,938 (-)RGD
Celera1453,392,500 - 53,396,161 (-)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_011190   ⟹   NP_035320
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391455,824,897 - 55,828,478 (-)NCBI
GRCm381455,587,440 - 55,591,021 (-)NCBI
MGSCv371456,206,277 - 56,209,938 (-)RGD
Celera1453,392,500 - 53,396,161 (-)RGD
cM Map14 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001025026   ⟸   NM_001029855
- Peptide Label: isoform 2
- UniProtKB: G3X9V0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_035320   ⟸   NM_011190
- Peptide Label: isoform 1
- UniProtKB: O35562 (UniProtKB/Swiss-Prot),   P97372 (UniProtKB/Swiss-Prot),   Q5SVP3 (UniProtKB/TrEMBL),   A0A1G5SJA5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000107009   ⟸   ENSMUST00000111378
RefSeq Acc Id: ENSMUSP00000125596   ⟸   ENSMUST00000159687
RefSeq Acc Id: ENSMUSP00000123798   ⟸   ENSMUST00000161807
Protein Domains
Proteasome activator PA28 C-terminal   Proteasome activator PA28 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97372-F1-model_v2 AlphaFold P97372 1-239 view protein structure

Promoters
RGD ID:8682434
Promoter ID:EPDNEW_M19248
Type:initiation region
Name:Psme2_1
Description:Mus musculus proteasome (prosome, macropain) activator subunit2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19249  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381455,590,924 - 55,590,984EPDNEW
RGD ID:8682436
Promoter ID:EPDNEW_M19249
Type:initiation region
Name:Psme2_2
Description:Mus musculus proteasome (prosome, macropain) activator subunit2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19248  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381455,591,113 - 55,591,173EPDNEW
RGD ID:6847131
Promoter ID:MM_ACW:16081
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour
Transcripts:PSME2.GSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361456,208,166 - 56,208,666 (-)MPROMDB
RGD ID:6825309
Promoter ID:MM_KWN:16962
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Spleen
Transcripts:ENSMUST00000111378,   NM_001029855,   NM_011190
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361456,209,761 - 56,210,387 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1096365 AgrOrtholog
Ensembl Genes ENSMUSG00000078153 UniProtKB/Swiss-Prot
  ENSMUSG00000079197 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000104958.2 UniProtKB/Swiss-Prot
  ENSMUST00000111378 ENTREZGENE
  ENSMUST00000111378.10 UniProtKB/TrEMBL
  ENSMUST00000159687.2 UniProtKB/TrEMBL
  ENSMUST00000161807 ENTREZGENE
  ENSMUST00000161807.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.120.180 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PA28_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PA28_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PA28_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proteasome_activ_PA28 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proteasome_activ_PA28_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proteasome_activ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19188 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  mmu:621823 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1096365 ENTREZGENE
NCBI Gene 19188 ENTREZGENE
PANTHER PROTEASOME ACTIVATOR COMPLEX SUBUNIT 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10660 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PA28_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PA28_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Psme2 PhenoGen
Superfamily-SCOP SSF47216 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1G5SJA5 ENTREZGENE
  E0CZ90_MOUSE UniProtKB/TrEMBL
  G3X9V0 ENTREZGENE, UniProtKB/TrEMBL
  O35562 ENTREZGENE
  P97372 ENTREZGENE, UniProtKB/Swiss-Prot
  Q5SVP3 ENTREZGENE, UniProtKB/TrEMBL
  Q99LN3_MOUSE UniProtKB/TrEMBL
UniProt Secondary O35562 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-06 Psme2  proteasome (prosome, macropain) activator subunit 2 (PA28 beta)    proteasome (prosome, macropain) 28 subunit, beta  Symbol and/or name change 5135510 APPROVED