Aqp7 (aquaporin 7) - Rat Genome Database

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Gene: Aqp7 (aquaporin 7) Mus musculus
Analyze
Symbol: Aqp7
Name: aquaporin 7
RGD ID: 736376
MGI Page MGI
Description: Predicted to enable glycerol channel activity; urea channel activity; and water channel activity. Acts upstream of or within glycerol transmembrane transport and renal water absorption. Located in plasma membrane. Colocalizes with lipid droplet. Is expressed in early conceptus; genitourinary system; inner ear; and liver. Orthologous to several human genes including AQP7 (aquaporin 7).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A; AQ; AQP-7; AQP7L; AQPap; aquaglyceroporin-7; aquaporin-7
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39441,033,074 - 41,048,237 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl441,033,074 - 41,048,139 (-)EnsemblGRCm39 Ensembl
GRCm38441,033,074 - 41,048,237 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl441,033,074 - 41,048,139 (-)EnsemblGRCm38mm10GRCm38
MGSCv37440,980,107 - 40,995,169 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36441,221,748 - 41,236,641 (-)NCBIMGSCv36mm8
Celera440,693,722 - 40,709,136 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map420.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
(R)-adrenaline  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
acetamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
bexarotene  (ISO)
bisphenol A  (EXP,ISO)
calcitriol  (ISO)
chlorpyrifos  (EXP)
choline  (EXP)
cisplatin  (ISO)
Citreoviridin  (EXP,ISO)
clofibrate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dibenzofurans  (EXP)
dimethylarsinic acid  (ISO)
dipentyl phthalate  (ISO)
diprotium oxide  (ISO)
disodium selenite  (EXP,ISO)
diuron  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
fenofibrate  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
furan  (ISO)
genistein  (EXP)
glycerol  (ISO)
hydrogen cyanide  (EXP)
indometacin  (ISO)
L-methionine  (EXP)
lycopene  (EXP)
mercaptoethanol  (EXP)
mercury dichloride  (EXP,ISO)
metformin  (ISO)
methylmercury chloride  (ISO)
milrinone  (ISO)
Muraglitazar  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP)
Phenylamil  (EXP)
pioglitazone  (EXP)
pirinixic acid  (EXP,ISO)
potassium cyanide  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
streptozocin  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
Tesaglitazar  (ISO)
thiamine(1+) chloride  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
troglitazone  (EXP,ISO)
urea  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)
water  (ISO)
zinc dichloride  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Adipose tissue expression of the glycerol channel Aquaporin-7 gene is altered in severe obesity but not in Type 2 diabetes. Ceperuelo-Mallafre V, etal., J Clin Endocrinol Metab. 2007 Jun 12;.
2. Aquaporin expression is downregulated in a murine model of colitis and in patients with ulcerative colitis, Crohn's disease and infectious colitis. Hardin JA, etal., Cell Tissue Res. 2004 Nov;318(2):313-23. Epub 2004 Aug 27.
3. Aquaporins in the kidney. Kwon TH, etal., Handb Exp Pharmacol. 2009;(190):95-132. doi: 10.1007/978-3-540-79885-9_5.
4. Increased AQP7 abundance in skeletal muscle from obese men with type 2 diabetes. Lebeck J, etal., Am J Physiol Endocrinol Metab. 2018 Sep 1;315(3):E367-E373. doi: 10.1152/ajpendo.00468.2017. Epub 2018 May 21.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9714739   PMID:9757370   PMID:9822113   PMID:10232700   PMID:10349636   PMID:10788316   PMID:11042159   PMID:11066060   PMID:11076861   PMID:11217851   PMID:11457862   PMID:11972053  
PMID:12031518   PMID:12351183   PMID:12351427   PMID:12477932   PMID:14610273   PMID:15489334   PMID:15591341   PMID:15746100   PMID:15998844   PMID:16009937   PMID:16079275   PMID:16141072  
PMID:16141073   PMID:16339044   PMID:16602821   PMID:17052846   PMID:17077387   PMID:17123523   PMID:17245390   PMID:17576812   PMID:18829704   PMID:19005169   PMID:19297367   PMID:19367412  
PMID:20573496   PMID:21130427   PMID:21282332   PMID:21873635   PMID:21968069   PMID:22415076   PMID:22877989   PMID:23290745   PMID:25643985   PMID:26634435   PMID:26847765   PMID:27455244  
PMID:27746040   PMID:29890131   PMID:32631905   PMID:33097799   PMID:34540996   PMID:34807469   PMID:37432580   PMID:37691043   PMID:37879294   PMID:38064372  


Genomics

Comparative Map Data
Aqp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39441,033,074 - 41,048,237 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl441,033,074 - 41,048,139 (-)EnsemblGRCm39 Ensembl
GRCm38441,033,074 - 41,048,237 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl441,033,074 - 41,048,139 (-)EnsemblGRCm38mm10GRCm38
MGSCv37440,980,107 - 40,995,169 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36441,221,748 - 41,236,641 (-)NCBIMGSCv36mm8
Celera440,693,722 - 40,709,136 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map420.83NCBI
AQP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38933,383,191 - 33,402,568 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl933,383,179 - 33,402,682 (-)EnsemblGRCh38hg38GRCh38
GRCh37933,383,189 - 33,402,566 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36933,374,948 - 33,392,517 (-)NCBINCBI36Build 36hg18NCBI36
Build 34933,374,947 - 33,392,517NCBI
Celera933,315,070 - 33,332,637 (-)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef933,341,505 - 33,358,953 (-)NCBIHuRef
CHM1_1933,384,744 - 33,402,308 (-)NCBICHM1_1
T2T-CHM13v2.0933,401,795 - 33,421,171 (-)NCBIT2T-CHM13v2.0
Aqp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8560,968,495 - 60,982,618 (-)NCBIGRCr8
mRatBN7.2556,171,649 - 56,186,642 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl556,172,519 - 56,186,642 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx558,138,736 - 58,152,556 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0559,957,884 - 59,971,702 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0559,952,637 - 59,966,600 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0557,358,297 - 57,372,332 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,358,327 - 57,372,239 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0561,888,637 - 61,902,549 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4558,433,731 - 58,447,853 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1558,433,909 - 58,448,032 (-)NCBI
Celera554,784,415 - 54,798,541 (-)NCBICelera
Cytogenetic Map5q22NCBI
Aqp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554722,283,426 - 2,297,251 (+)NCBIChiLan1.0ChiLan1.0
AQP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21191,201,225 - 91,220,849 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1991,207,167 - 91,226,803 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0933,160,982 - 33,180,638 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1933,971,842 - 33,983,454 (-)NCBIpanpan1.1PanPan1.1panPan2
AQP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11150,474,007 - 50,488,191 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1149,104,054 - 49,118,284 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01151,414,635 - 51,428,870 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1151,413,367 - 51,428,758 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11150,078,662 - 50,092,894 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01149,945,887 - 49,960,128 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01150,710,993 - 50,725,230 (-)NCBIUU_Cfam_GSD_1.0
Aqp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947165,351,053 - 165,367,563 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365241,898,635 - 1,915,078 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AQP7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11033,098,746 - 33,130,245 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21037,361,028 - 37,376,629 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AQP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11246,866,519 - 46,886,525 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603843,758,462 - 43,777,506 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aqp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473638,130,992 - 38,148,444 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aqp7
537 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1108
Count of miRNA genes:479
Interacting mature miRNAs:558
Transcripts:ENSMUST00000030136, ENSMUST00000054945, ENSMUST00000144201, ENSMUST00000149517
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1301473Triglq1_mtriglyceride QTL 1 (mouse)Not determined4868324042683429Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
1302010Wta1_mweight adult 1 (mouse)Not determined4868324042683429Mouse
1302184Aaom1_mautoimmune aoritis in MRL mice 1 (mouse)Not determined42432229946332776Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1302125Lxw1_mlupus BXSB x NZW 1 (mouse)Not determined4868324042683429Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
1558992Ses8_msalmonella enteritidis susceptibility 8 (mouse)Not determined4868324042683429Mouse
4141302Ssrq5_mstress response QTL 5 (mouse)Not determined868324042683430Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
4142290Ssrq9_mstress response QTL 9 (mouse)Not determined3439516046332776Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763283678Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
10412178Habiir2_mhyperoxic acute lung injury imprinted region 2 (mouse)Not determined43945212663283678Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
25440481Moaq1_mmodifier of alien QTL 1 (mouse)41950000046000000Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse

Markers in Region
Aqp7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37440,981,961 - 40,982,631UniSTSGRCm37
Celera440,695,576 - 40,696,246UniSTS
Cytogenetic Map4B1UniSTS
cM MapUN UniSTS
cM Map4 UniSTS
Aqp7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38441,034,928 - 41,035,598UniSTSGRCm38
MGSCv37440,981,961 - 40,982,631UniSTSGRCm37
Celera440,695,576 - 40,696,246UniSTS
Cytogenetic Map4B1UniSTS
cM MapUN UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001378638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001378639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001378640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001378641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001378642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006537559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006537560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006537563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017319925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB010100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB027516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB056091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB056099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL837521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU945845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000030136   ⟹   ENSMUSP00000030136
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,033,074 - 41,048,139 (-)Ensembl
GRCm38.p6 Ensembl441,033,074 - 41,048,139 (-)Ensembl
RefSeq Acc Id: ENSMUST00000054945   ⟹   ENSMUSP00000093007
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,033,074 - 41,045,448 (-)Ensembl
GRCm38.p6 Ensembl441,033,074 - 41,045,448 (-)Ensembl
RefSeq Acc Id: ENSMUST00000144201
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,034,893 - 41,040,967 (-)Ensembl
GRCm38.p6 Ensembl441,034,893 - 41,040,967 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149517
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,035,135 - 41,036,310 (-)Ensembl
GRCm38.p6 Ensembl441,035,135 - 41,036,310 (-)Ensembl
RefSeq Acc Id: NM_001378638   ⟹   NP_001365567
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,033,074 - 41,047,962 (-)NCBI
GRCm38441,033,074 - 41,047,962 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001378639   ⟹   NP_001365568
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,033,074 - 41,047,962 (-)NCBI
GRCm38441,033,074 - 41,047,962 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001378640   ⟹   NP_001365569
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,033,074 - 41,047,962 (-)NCBI
GRCm38441,033,074 - 41,047,962 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001378641   ⟹   NP_001365570
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,033,074 - 41,047,962 (-)NCBI
GRCm38441,033,074 - 41,047,962 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001378642   ⟹   NP_001365571
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,033,074 - 41,047,962 (-)NCBI
GRCm38441,033,074 - 41,047,962 (-)NCBI
Sequence:
RefSeq Acc Id: NM_007473   ⟹   NP_031499
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,033,074 - 41,048,136 (-)NCBI
GRCm38441,033,074 - 41,048,136 (-)NCBI
MGSCv37440,980,107 - 40,995,169 (-)RGD
Celera440,693,722 - 40,709,136 (-)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006537559   ⟹   XP_006537622
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,034,182 - 41,048,205 (-)NCBI
GRCm38441,034,193 - 41,048,205 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006537560   ⟹   XP_006537623
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,034,163 - 41,048,157 (-)NCBI
GRCm38441,034,182 - 41,048,157 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006537563   ⟹   XP_006537626
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,034,182 - 41,048,132 (-)NCBI
GRCm38441,034,193 - 41,048,132 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017319925   ⟹   XP_017175414
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,036,144 - 41,048,237 (-)NCBI
GRCm38441,036,144 - 41,048,237 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253099   ⟹   XP_030108959
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,034,182 - 41,047,601 (-)NCBI
GRCm38441,034,193 - 41,047,600 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036163606   ⟹   XP_036019499
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,034,193 - 41,045,393 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_031499   ⟸   NM_007473
- Peptide Label: isoform 2
- UniProtKB: Q8C630 (UniProtKB/Swiss-Prot),   O54794 (UniProtKB/Swiss-Prot),   Q5DX24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006537623   ⟸   XM_006537560
- Peptide Label: isoform X2
- UniProtKB: Q8C630 (UniProtKB/Swiss-Prot),   O54794 (UniProtKB/Swiss-Prot),   Q5DX24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006537622   ⟸   XM_006537559
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006537626   ⟸   XM_006537563
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017175414   ⟸   XM_017319925
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_030108959   ⟸   XM_030253099
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001365568   ⟸   NM_001378639
- Peptide Label: isoform 2
- UniProtKB: O54794 (UniProtKB/Swiss-Prot),   Q8C630 (UniProtKB/Swiss-Prot),   Q5DX24 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001365571   ⟸   NM_001378642
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001365569   ⟸   NM_001378640
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001365567   ⟸   NM_001378638
- Peptide Label: isoform 1
RefSeq Acc Id: NP_001365570   ⟸   NM_001378641
- Peptide Label: isoform 4
RefSeq Acc Id: ENSMUSP00000093007   ⟸   ENSMUST00000054945
RefSeq Acc Id: ENSMUSP00000030136   ⟸   ENSMUST00000030136
RefSeq Acc Id: XP_036019499   ⟸   XM_036163606
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O54794-F1-model_v2 AlphaFold O54794 1-303 view protein structure

Promoters
RGD ID:6834889
Promoter ID:MM_KWN:37132
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000015110
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36440,982,981 - 40,983,481 (-)MPROMDB
RGD ID:6834886
Promoter ID:MM_KWN:37134
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ENSMUST00000054945
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36440,992,311 - 40,992,811 (-)MPROMDB
RGD ID:6834887
Promoter ID:MM_KWN:37135
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day6
Transcripts:ENSMUST00000116345,   OTTMUST00000015107
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36440,994,736 - 40,995,236 (-)MPROMDB
RGD ID:6883074
Promoter ID:EPDNEW_M4988
Type:initiation region
Name:Aqp7_1
Description:Mus musculus aquaporin 7 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4989  EPDNEW_M4990  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38441,045,437 - 41,045,497EPDNEW
RGD ID:6883076
Promoter ID:EPDNEW_M4989
Type:initiation region
Name:Aqp7_2
Description:Mus musculus aquaporin 7 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4988  EPDNEW_M4990  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38441,047,962 - 41,048,022EPDNEW
RGD ID:6883080
Promoter ID:EPDNEW_M4990
Type:initiation region
Name:Aqp7_3
Description:Mus musculus aquaporin 7 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4988  EPDNEW_M4989  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38441,048,112 - 41,048,172EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1314647 AgrOrtholog
Ensembl Genes ENSMUSG00000028427 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000030136 ENTREZGENE
  ENSMUST00000030136.13 UniProtKB/Swiss-Prot
  ENSMUST00000054945 ENTREZGENE
  ENSMUST00000054945.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1080.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Aquaporin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11832 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1314647 ENTREZGENE
NCBI Gene 11832 ENTREZGENE
PANTHER AQUAPORIN OR AQUAGLYCEROPORIN RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR43829:SF15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aqp7 PhenoGen
PRINTS AQUAPORIN7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MINTRINSICP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF81338 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AQP7_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q5DX24 ENTREZGENE, UniProtKB/TrEMBL
  Q8C630 ENTREZGENE
UniProt Secondary Q8C630 UniProtKB/Swiss-Prot