Chdh (choline dehydrogenase) - Rat Genome Database

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Gene: Chdh (choline dehydrogenase) Rattus norvegicus
Analyze
Symbol: Chdh
Name: choline dehydrogenase
RGD ID: 735166
Description: Enables choline dehydrogenase activity. Predicted to be involved in obsolete glycine betaine biosynthetic process from choline. Located in mitochondrial inner membrane. Orthologous to human CHDH (choline dehydrogenase); PARTICIPATES IN choline metabolic pathway; glycine N-methyltransferase deficiency pathway; homocystinuria pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CDH; CHD; choline dehydrogenase precursor; choline dehydrogenase, mitochondrial; LOC290551; MGC93763
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8165,199,738 - 5,232,067 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl165,200,763 - 5,232,997 (+)EnsemblGRCr8
mRatBN7.2165,194,269 - 5,225,541 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,194,269 - 5,225,537 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx165,206,338 - 5,237,597 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0166,351,765 - 6,383,024 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0165,203,745 - 5,235,066 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd165,195,888 - 5,227,204 (+)NCBI
Lyon_Normotensive165,195,321 - 5,226,636 (+)NCBI
Lyon_Hypertensive165,194,205 - 5,225,517 (+)NCBI
F344_StmMcwi165,226,548 - 5,257,655 (+)NCBI
Rnor_6.0166,078,083 - 6,109,386 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl166,078,122 - 6,109,382 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.0166,009,399 - 6,042,916 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4165,349,304 - 5,380,800 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera169,958,327 - 9,989,994 (-)NCBICelera
RGSC_v3.1165,349,301 - 5,380,794 (+)NCBI
Cytogenetic Map16p16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
hexadecanoic acid  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
pirinixic acid  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
temozolomide  (ISO)
teriflunomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Functional expression and processing of rat choline dehydrogenase precursor. Huang S and Lin Q, Biochem Biophys Res Commun 2003 Sep 19;309(2):344-50.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12865426   PMID:16920841   PMID:18614015   PMID:34800366  


Genomics

Comparative Map Data
Chdh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8165,199,738 - 5,232,067 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl165,200,763 - 5,232,997 (+)EnsemblGRCr8
mRatBN7.2165,194,269 - 5,225,541 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,194,269 - 5,225,537 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx165,206,338 - 5,237,597 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0166,351,765 - 6,383,024 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0165,203,745 - 5,235,066 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd165,195,888 - 5,227,204 (+)NCBI
Lyon_Normotensive165,195,321 - 5,226,636 (+)NCBI
Lyon_Hypertensive165,194,205 - 5,225,517 (+)NCBI
F344_StmMcwi165,226,548 - 5,257,655 (+)NCBI
Rnor_6.0166,078,083 - 6,109,386 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl166,078,122 - 6,109,382 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.0166,009,399 - 6,042,916 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4165,349,304 - 5,380,800 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera169,958,327 - 9,989,994 (-)NCBICelera
RGSC_v3.1165,349,301 - 5,380,794 (+)NCBI
Cytogenetic Map16p16NCBI
CHDH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38353,812,335 - 53,846,419 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl353,812,335 - 53,846,468 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh37353,846,362 - 53,880,446 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36353,826,679 - 53,855,216 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34353,826,680 - 53,855,216NCBI
Celera353,817,666 - 53,847,699 (-)NCBICelera
Cytogenetic Map3p21.1NCBI
HuRef353,898,841 - 53,928,936 (-)NCBIHuRef
CHM1_1353,801,960 - 53,832,058 (-)NCBICHM1_1
T2T-CHM13v2.0353,845,582 - 53,879,657 (-)NCBIT2T-CHM13v2.0
Chdh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391429,730,957 - 29,762,423 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1429,730,856 - 29,763,372 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381430,008,901 - 30,040,468 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1430,009,023 - 30,040,527 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv371430,822,186 - 30,853,652 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361428,850,312 - 28,867,258 (+)NCBIMGSCv36mm8
Celera1426,264,832 - 26,296,311 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1418.4NCBI
Chdh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554303,799,970 - 3,805,474 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_0049554303,797,924 - 3,831,326 (-)NCBIChiLan1.0ChiLan1.0
CHDH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2253,806,541 - 53,838,279 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1353,813,039 - 53,843,042 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0353,751,179 - 53,784,437 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1354,976,046 - 55,003,934 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl354,976,780 - 54,982,991 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
CHDH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12036,150,214 - 36,188,976 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2036,150,229 - 36,187,068 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2036,088,356 - 36,126,155 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02036,425,188 - 36,463,249 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2036,424,511 - 36,463,238 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12035,866,830 - 35,904,754 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02036,225,474 - 36,263,299 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02036,442,996 - 36,480,855 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Chdh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap1247,159,021 - 47,188,380 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_024405118171,342,084 - 171,373,577 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364734,482,170 - 4,506,763 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364734,479,942 - 4,512,369 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHDH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1335,910,698 - 35,948,683 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.11335,910,688 - 35,950,438 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21338,981,271 - 39,019,109 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHDH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap12285,905,827 - 85,937,135 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_023666041151,662,423 - 151,694,825 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.12215,197,568 - 15,228,613 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2215,197,170 - 15,205,352 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Chdh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248223,336,272 - 3,390,325 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046248223,355,355 - 3,390,329 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Chdh
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1135,748,226 - 5,755,276 (+)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in Chdh
150 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:172
Count of miRNA genes:120
Interacting mature miRNAs:144
Transcripts:ENSRNOT00000021407
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16423421216278352Rat
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16423421216278352Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421216061395Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
631524Bp75Blood pressure QTL 750.05arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)161177108157035Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16423433317730812Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
268 156 507 951 3972 1011 1727 124 874 245 856 154 4270 1678 438 3878 28 1388 717 895 150 148

Sequence


Ensembl Acc Id: ENSRNOT00000021407   ⟹   ENSRNOP00000021407
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl165,200,763 - 5,232,063 (+)Ensembl
mRatBN7.2 Ensembl165,194,269 - 5,225,537 (+)Ensembl
Rnor_6.0 Ensembl166,078,122 - 6,109,382 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000153834   ⟹   ENSRNOP00000111940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl165,224,007 - 5,232,997 (+)Ensembl
RefSeq Acc Id: NM_198731   ⟹   NP_942026
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,200,801 - 5,232,067 (+)NCBI
mRatBN7.2165,194,269 - 5,225,541 (+)NCBI
Dahl_SR_JrHsd165,195,888 - 5,227,204 (+)NCBI
Lyon_Normotensive165,195,321 - 5,226,636 (+)NCBI
Lyon_Hypertensive165,194,205 - 5,225,517 (+)NCBI
F344_StmMcwi165,226,548 - 5,257,655 (+)NCBI
Rnor_6.0166,078,122 - 6,109,386 (+)NCBI
Rnor_5.0166,009,399 - 6,042,916 (+)NCBI
RGSC_v3.4165,349,304 - 5,380,800 (+)RGD
Celera169,958,327 - 9,989,994 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252579   ⟹   XP_006252641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,200,850 - 5,232,067 (+)NCBI
mRatBN7.2165,194,325 - 5,225,541 (+)NCBI
Rnor_6.0166,078,083 - 6,109,386 (+)NCBI
Rnor_5.0166,009,399 - 6,042,916 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770984   ⟹   XP_008769206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,217,626 - 5,232,067 (+)NCBI
mRatBN7.2165,211,098 - 5,225,541 (+)NCBI
Rnor_6.0166,094,532 - 6,109,386 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063275130   ⟹   XP_063131200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,200,775 - 5,232,067 (+)NCBI
RefSeq Acc Id: XM_063275131   ⟹   XP_063131201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,217,593 - 5,232,067 (+)NCBI
RefSeq Acc Id: XM_063275132   ⟹   XP_063131202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8165,199,738 - 5,232,067 (+)NCBI
RefSeq Acc Id: NP_942026   ⟸   NM_198731
- UniProtKB: Q6UPE0 (UniProtKB/Swiss-Prot),   A0ABK0LLW2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252641   ⟸   XM_006252579
- Peptide Label: isoform X1
- UniProtKB: Q6UPE0 (UniProtKB/Swiss-Prot),   A0ABK0LLW2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008769206   ⟸   XM_008770984
- Peptide Label: isoform X1
- UniProtKB: Q6UPE0 (UniProtKB/Swiss-Prot),   A0ABK0LLW2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021407   ⟸   ENSRNOT00000021407
RefSeq Acc Id: XP_063131202   ⟸   XM_063275132
- Peptide Label: isoform X1
- UniProtKB: Q6UPE0 (UniProtKB/Swiss-Prot),   A0ABK0LLW2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131200   ⟸   XM_063275130
- Peptide Label: isoform X1
- UniProtKB: Q6UPE0 (UniProtKB/Swiss-Prot),   A0ABK0LLW2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131201   ⟸   XM_063275131
- Peptide Label: isoform X1
- UniProtKB: Q6UPE0 (UniProtKB/Swiss-Prot),   A0ABK0LLW2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000111940   ⟸   ENSRNOT00000153834
Protein Domains
Glucose-methanol-choline oxidoreductase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6UPE0-F1-model_v2 AlphaFold Q6UPE0 1-599 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699909
Promoter ID:EPDNEW_R10433
Type:initiation region
Name:Chdh_1
Description:choline dehydrogenase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0166,078,114 - 6,078,174EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735166 AgrOrtholog
BioCyc Gene G2FUF-12205 BioCyc
BioCyc Pathway CHOLINE-BETAINE-ANA-PWY [choline degradation I] BioCyc
BioCyc Pathway Image CHOLINE-BETAINE-ANA-PWY BioCyc
Ensembl Genes ENSRNOG00000015859 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055020751 UniProtKB/Swiss-Prot
  ENSRNOG00060013631 UniProtKB/Swiss-Prot
  ENSRNOG00065016107 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000021407 ENTREZGENE
  ENSRNOT00000021407.6 UniProtKB/Swiss-Prot
  ENSRNOT00000153834 ENTREZGENE
  ENSRNOT00055035420 UniProtKB/Swiss-Prot
  ENSRNOT00060023266 UniProtKB/Swiss-Prot
  ENSRNOT00065026784 UniProtKB/Swiss-Prot
Gene3D-CATH 3.50.50.60 UniProtKB/Swiss-Prot
  Glucose Oxidase, domain 3 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7108667 IMAGE-MGC_LOAD
InterPro FAD/NAD-bd_sf UniProtKB/Swiss-Prot
  GMC_OxRdtase UniProtKB/Swiss-Prot
  GMC_OxRdtase_N UniProtKB/Swiss-Prot
  GMC_OxRtase_C UniProtKB/Swiss-Prot
KEGG Report rno:290551 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93763 IMAGE-MGC_LOAD
NCBI Gene 290551 ENTREZGENE
PANTHER CHOLINE DEHYDROGENASE, MITOCHONDRIAL UniProtKB/Swiss-Prot
  PTHR11552 UniProtKB/Swiss-Prot
Pfam GMC_oxred_C UniProtKB/Swiss-Prot
  GMC_oxred_N UniProtKB/Swiss-Prot
PhenoGen Chdh PhenoGen
PIRSF Alcohol_oxidase UniProtKB/Swiss-Prot
PROSITE GMC_OXRED_1 UniProtKB/Swiss-Prot
  GMC_OXRED_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015859 RatGTEx
  ENSRNOG00055020751 RatGTEx
  ENSRNOG00060013631 RatGTEx
  ENSRNOG00065016107 RatGTEx
Superfamily-SCOP FAD-linked reductases, C-terminal domain UniProtKB/Swiss-Prot
  SSF51905 UniProtKB/Swiss-Prot
UniProt A0ABK0LLW2 ENTREZGENE, UniProtKB/TrEMBL
  CHDH_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-07-08 Chdh  choline dehydrogenase  LOC290551  choline dehydrogenase precursor  Symbol and Name updated 1299863 APPROVED