Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Ptgfrn (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PTGFRN mRNA | CTD | PMID:36331819 | 1,1-dichloroethene | increases expression | ISO | Ptgfrn (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of PTGFRN mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | multiple interactions | ISO | Ptgfrn (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PTGFRN mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Ethinyl Estradiol affects the expression of PTGFRN mRNA | CTD | PMID:16079270 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of PTGFRN mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PTGFRN mRNA | CTD | PMID:21215274 and PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PTGFRN mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ptgfrn (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PTGFRN mRNA | CTD | PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ptgfrn (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PTGFRN mRNA] | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ptgfrn (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PTGFRN mRNA | CTD | PMID:15034205 | 2,4-dinitrotoluene | affects expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of PTGFRN mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | increases expression | EXP | | 6480464 | Lactic Acid results in increased expression of PTGFRN mRNA | CTD | PMID:30851411 | 3-chloropropane-1,2-diol | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in increased expression of PTGFRN protein | CTD | PMID:34915118 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of PTGFRN mRNA | CTD | PMID:30723492 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Ptgfrn (Mus musculus) | 6480464 | Fenretinide results in decreased expression of PTGFRN mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of PTGFRN mRNA | CTD | PMID:30047161 | 6-propyl-2-thiouracil | decreases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of PTGFRN mRNA | CTD | PMID:36843608 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of PTGFRN mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of PTGFRN 3' UTR | CTD | PMID:30157460 | aflatoxin B1 | increases methylation | EXP | | 6480464 | Aflatoxin B1 results in increased methylation of PTGFRN intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | EXP | | 6480464 | aflatoxin B2 results in increased methylation of PTGFRN intron | CTD | PMID:30157460 | alendronic acid | affects expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Alendronate affects the expression of PTGFRN mRNA | CTD | PMID:16079270 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of PTGFRN mRNA | CTD | PMID:33167477 | amitrole | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of PTGFRN mRNA | CTD | PMID:30047161 | ammonium chloride | affects expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of PTGFRN mRNA | CTD | PMID:16483693 | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of PTGFRN mRNA | CTD | PMID:33212167 | benzo[a]pyrene | decreases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Benzo(a)pyrene results in decreased expression of PTGFRN mRNA | CTD | PMID:21839799 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of PTGFRN 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | Ptgfrn (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of PTGFRN 3' UTR more ... | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Ptgfrn (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of PTGFRN mRNA | CTD | PMID:15034205 and PMID:19770486 | benzo[a]pyrene | multiple interactions | ISO | Ptgfrn (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of PTGFRN mRNA] | CTD | PMID:15034205 | bisphenol A | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PTGFRN mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | increases expression | ISO | Ptgfrn (Mus musculus) | 6480464 | bisphenol A results in increased expression of PTGFRN mRNA | CTD | PMID:32156529 | Bisphenol B | increases expression | EXP | | 6480464 | bisphenol B results in increased expression of PTGFRN protein | CTD | PMID:34186270 | butanal | decreases expression | EXP | | 6480464 | butyraldehyde results in decreased expression of PTGFRN mRNA | CTD | PMID:26079696 | cadmium dichloride | decreases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of PTGFRN mRNA | CTD | PMID:33453195 | caffeine | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Caffeine results in increased expression of PTGFRN mRNA | CTD | PMID:20864626 | carbamazepine | affects expression | EXP | | 6480464 | Carbamazepine affects the expression of PTGFRN mRNA | CTD | PMID:25979313 | choline | multiple interactions | ISO | Ptgfrn (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PTGFRN mRNA | CTD | PMID:20938992 | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of PTGFRN mRNA | CTD | PMID:27594783 | clobetasol | increases expression | ISO | Ptgfrn (Mus musculus) | 6480464 | Clobetasol results in increased expression of PTGFRN mRNA | CTD | PMID:27462272 | clotrimazole | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Clotrimazole results in increased expression of PTGFRN mRNA | CTD | PMID:30047161 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of PTGFRN mRNA | CTD | PMID:25562108 | dicrotophos | increases expression | EXP | | 6480464 | dicrotophos results in increased expression of PTGFRN mRNA | CTD | PMID:28302478 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PTGFRN mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of PTGFRN mRNA | CTD | PMID:29803840 | ethanol | increases expression | ISO | Ptgfrn (Mus musculus) | 6480464 | Ethanol results in increased expression of PTGFRN mRNA | CTD | PMID:30319688 | fenvalerate | affects methylation | ISO | Ptgfrn (Mus musculus) | 6480464 | fenvalerate affects the methylation of PTGFRN gene | CTD | PMID:23548413 | flavonoids | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Flavonoids results in increased expression of PTGFRN mRNA | CTD | PMID:18035473 | folic acid | multiple interactions | ISO | Ptgfrn (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | gentamycin | decreases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of PTGFRN mRNA | CTD | PMID:33387578 | ivermectin | decreases expression | EXP | | 6480464 | Ivermectin results in decreased expression of PTGFRN protein | CTD | PMID:32959892 | L-methionine | multiple interactions | ISO | Ptgfrn (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PTGFRN mRNA | CTD | PMID:20938992 | lipopolysaccharide | multiple interactions | EXP | | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of PTGFRN mRNA | CTD | PMID:35811015 | methimazole | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of PTGFRN mRNA | CTD | PMID:30047161 | methoxyacetic acid | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | methoxyacetic acid results in increased expression of PTGFRN mRNA | CTD | PMID:20864626 | methyl methanesulfonate | decreases expression | EXP | | 6480464 | Methyl Methanesulfonate results in decreased expression of PTGFRN mRNA | CTD | PMID:23649840 | methylmercury chloride | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | methylmercuric chloride results in increased expression of PTGFRN mRNA | CTD | PMID:20864626 | Monobutylphthalate | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | monobutyl phthalate results in increased expression of PTGFRN mRNA | CTD | PMID:20864626 | N-nitrosodiethylamine | increases expression | ISO | Ptgfrn (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of PTGFRN mRNA | CTD | PMID:24535843 | ochratoxin A | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | ochratoxin A results in increased expression of PTGFRN mRNA | CTD | PMID:16251485 | oxaliplatin | multiple interactions | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of PTGFRN mRNA | CTD | PMID:25729387 | oxaliplatin | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | oxaliplatin results in increased expression of PTGFRN mRNA | CTD | PMID:25729387 | paracetamol | affects expression | ISO | Ptgfrn (Mus musculus) | 6480464 | Acetaminophen affects the expression of PTGFRN mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of PTGFRN mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PTGFRN mRNA | CTD | PMID:21420995 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ptgfrn (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PTGFRN mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of PTGFRN protein | CTD | PMID:26879310 | pirinixic acid | increases expression | ISO | Ptgfrn (Mus musculus) | 6480464 | pirinixic acid results in increased expression of PTGFRN mRNA | CTD | PMID:18301758 | pirinixic acid | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | pirinixic acid results in increased expression of PTGFRN mRNA | CTD | PMID:19162173 | progesterone | decreases expression | EXP | | 6480464 | Progesterone results in decreased expression of PTGFRN mRNA | CTD | PMID:21795739 | quercetin | increases expression | EXP | | 6480464 | Quercetin results in increased expression of PTGFRN mRNA | CTD | PMID:19729006 | quercetin | decreases expression | EXP | | 6480464 | Quercetin results in decreased expression of PTGFRN mRNA | CTD | PMID:21632981 | rac-lactic acid | increases expression | EXP | | 6480464 | Lactic Acid results in increased expression of PTGFRN mRNA | CTD | PMID:30851411 | raloxifene | affects expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Raloxifene Hydrochloride affects the expression of PTGFRN mRNA | CTD | PMID:16079270 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | EXP | | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of PTGFRN mRNA | CTD | PMID:35811015 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PTGFRN mRNA | CTD | PMID:27188386 | sodium fluoride | increases expression | ISO | Ptgfrn (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of PTGFRN protein | CTD | PMID:28918527 | Soman | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Soman results in increased expression of PTGFRN mRNA | CTD | PMID:19281266 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of PTGFRN mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | EXP | | 6480464 | Temozolomide results in decreased expression of PTGFRN mRNA | CTD | PMID:31758290 | testosterone | decreases expression | EXP | | 6480464 | Testosterone results in decreased expression of PTGFRN mRNA | CTD | PMID:33359661 | tetrachloromethane | affects expression | ISO | Ptgfrn (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of PTGFRN mRNA | CTD | PMID:17484886 | thioacetamide | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of PTGFRN mRNA | CTD | PMID:23411599 | titanium dioxide | affects expression | ISO | Ptgfrn (Mus musculus) | 6480464 | titanium dioxide affects the expression of PTGFRN mRNA | CTD | PMID:17656681 | topotecan | increases expression | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | Topotecan results in increased expression of PTGFRN mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | ISO | Ptgfrn (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of PTGFRN mRNA | CTD | PMID:25729387 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of PTGFRN mRNA | CTD | PMID:25979313 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of PTGFRN mRNA | CTD | PMID:23179753 and PMID:26272509 | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PTGFRN mRNA | CTD | PMID:27188386 | |