Gpr27 (G protein-coupled receptor 27)

Gene: Gpr27 (G protein-coupled receptor 27) Mus musculus

Analyze

Symbol:

Gpr27

Name:

G protein-coupled receptor 27

RGD ID:

733558

MGI Page

MGI

Description:

Predicted to enable G protein-coupled receptor activity. Acts upstream of or within positive regulation of insulin secretion involved in cellular response to glucose stimulus and positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway. Located in plasma membrane. Orthologous to human GPR27 (G protein-coupled receptor 27).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

probable G-protein coupled receptor 27; super conserved receptor expressed in brain 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPR27 (G protein-coupled receptor 27)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Gpr27 (G protein-coupled receptor 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpr27 (G protein-coupled receptor 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPR27 (G protein-coupled receptor 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPR27 (G protein-coupled receptor 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpr27 (G protein-coupled receptor 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPR27 (G protein-coupled receptor 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPR27 (G protein-coupled receptor 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpr27 (G protein-coupled receptor 27)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Gpr27 (G protein-coupled receptor 27)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GPR27 (G protein-coupled receptor 27)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gpr27 (G protein-coupled receptor 27)	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	gpr27	Alliance	DIOPT (PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	99,669,328 - 99,672,027 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	99,669,640 - 99,672,027 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	99,692,367 - 99,695,066 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	99,692,679 - 99,695,066 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	99,642,673 - 99,643,812 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	99,658,142 - 99,659,281 (+)	NCBI		MGSCv36	mm8
Celera	6	101,556,763 - 101,557,942 (+)	NCBI		Celera
Cytogenetic Map	6	D3	NCBI
cM Map	6	46.22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

malignant mesothelioma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4-hydroxyphenyl retinamide (EXP)

6-propyl-2-thiouracil (ISO)

ammonium chloride (ISO)

atrazine (ISO)

belinostat (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (ISO)

cadmium atom (ISO)

cisplatin (ISO)

clofibrate (EXP)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

dextran sulfate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

gentamycin (ISO)

maneb (EXP)

mercury dibromide (ISO)

panobinostat (ISO)

paracetamol (ISO)

paraquat (EXP)

phenylmercury acetate (ISO)

pirinixic acid (EXP)

resveratrol (ISO)

sarin (ISO)

SB 431542 (ISO)

sunitinib (ISO)

tetrachloromethane (EXP)

titanium dioxide (EXP)

trichloroethene (ISO)

trichostatin A (ISO)

tunicamycin (EXP)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IEA)

positive regulation of insulin secretion involved in cellular response to glucose stimulus (IMP)

positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway (IDA,IMP)

signal transduction (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IDA)

Molecular Function

G protein-coupled receptor activity (IBA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal endocrine pancreas physiology (IAGP)

decreased body weight (IAGP)

decreased circulating insulin level (IAGP)

decreased insulin secretion (IAGP)

impaired glucose tolerance (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system.	Matsumoto M, etal., Biochem Biophys Res Commun 2000 Jun 7;272(2):576-82.
2.	Electronic Transfer of Homolog Data	MGD and Homologene mouse data transfer
3.	MGDs mouse GO annotations	MGD data from the GO Consortium
4.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9479505	PMID:16602821	PMID:17273929	PMID:21873635	PMID:22253604	PMID:32221326	PMID:35326460

Genomics

Comparative Map Data

Gpr27
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	99,669,328 - 99,672,027 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	99,669,640 - 99,672,027 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	99,692,367 - 99,695,066 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	99,692,679 - 99,695,066 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	99,642,673 - 99,643,812 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	99,658,142 - 99,659,281 (+)	NCBI		MGSCv36	mm8
Celera	6	101,556,763 - 101,557,942 (+)	NCBI		Celera
Cytogenetic Map	6	D3	NCBI
cM Map	6	46.22	NCBI

GPR27
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	71,753,855 - 71,756,496 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	71,753,855 - 71,756,496 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	71,803,006 - 71,805,647 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	71,885,891 - 71,887,018 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	71,885,890 - 71,887,018	NCBI
Celera	3	71,733,794 - 71,734,921 (+)	NCBI		Celera
Cytogenetic Map	3	p13	NCBI
CHM1_1	3	71,754,610 - 71,755,737 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	71,793,122 - 71,795,766 (+)	NCBI		T2T-CHM13v2.0

Gpr27
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	133,884,894 - 133,886,027 (+)	NCBI		GRCr8
mRatBN7.2	4	132,328,364 - 132,329,497 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	132,328,364 - 132,329,497 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	137,745,693 - 137,746,826 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	133,526,475 - 133,527,608 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	132,144,746 - 132,145,879 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	132,137,793 - 132,138,926 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	132,137,793 - 132,138,926 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	196,629,031 - 196,630,164 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	134,541,534 - 134,542,667 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	134,786,374 - 134,787,508 (+)	NCBI
Celera	4	121,187,535 - 121,188,668 (+)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

Gpr27
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955421	16,352,643 - 16,353,094 (-)	NCBI	ChiLan1.0	ChiLan1.0

GPR27
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	71,713,162 - 71,715,808 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	71,717,950 - 71,720,596 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	71,693,611 - 71,696,247 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	73,050,542 - 73,052,347 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

GPR27
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	20	20,249,117 - 20,251,750 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	20,307,618 - 20,309,127 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	20,307,969 - 20,309,117 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	19,992,950 - 19,995,575 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	20,342,113 - 20,344,735 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	20,408,115 - 20,410,754 (-)	NCBI		UU_Cfam_GSD_1.0

Gpr27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404942	3,284,932 - 3,289,003 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936603	3,241,741 - 3,289,996 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR27
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	53,152,062 - 53,153,192 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	53,152,038 - 53,154,537 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

GPR27
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	32,708,228 - 32,709,820 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	32,708,599 - 32,709,729 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	134,068,927 - 134,071,765 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpr27
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624773	6,294,850 - 6,296,010 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624773	6,294,850 - 6,297,249 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gpr27
49 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	174
Count of miRNA genes:	163
Interacting mature miRNAs:	168
Transcripts:	ENSMUST00000101122
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
25440480	Moaq2_m	modifier of alien QTL 2 (mouse)					6	3050001	117476961	Mouse
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139076998	Mouse
10412157	Fl1n_m	fatty liver 1 in NSY (mouse)			Not determined		6	45290993	128811995	Mouse
4142259	Tabw2_m	tally ho associated body weight 2 (mouse)			Not determined			46912919	136400690	Mouse
25314319	Histh6_m	histamine hypersensitivity 6 (mouse)					6	48696934	125336963	Mouse
25314320	Histh5_m	histamine hypersensitivity 5 (mouse)					6	48696934	148351498	Mouse
1301962	Eila2_m	ethanol induced locomotor activity 2 (mouse)			Not determined		6	48703490	125333748	Mouse
1357683	Igf1sl1_m	IGF-1 serum levels 1 (mouse)			Not determined		6	52138693	116132228	Mouse
10412119	Stv_m	striatal volumne (mouse)			Not determined		6	60026991	100026967	Mouse
1300650	Bw18_m	body weight QTL 18 (mouse)			Not determined		6	66690851	100691013	Mouse
1301813	Skl3_m	skeletal size (tail length) 3 (mouse)			Not determined		6	70402880	104403016	Mouse
1301034	Egrm2_m	early growth rate (mouse)			Not determined		6	70402880	104403016	Mouse
1301876	Bits2_m	bitterness sensitivity 2 (mouse)			Not determined		6	70402880	104403016	Mouse
1300869	Stheal5_m	soft tissue heal 5 (mouse)			Not determined		6	71552042	105552160	Mouse
1301521	Pas1c_m	pulmonary adenoma susceptibility 1c (mouse)			Not determined		6	71958006	105958152	Mouse
1300954	Fcsa1_m	femoral cross-sectional area 1 (mouse)			Not determined		6	71958006	105958152	Mouse
13506930	Recrq9_m	recombination rate in male meiosis QTL 9 (mouse)					6	73476983	134676963	Mouse
12792979	Fbmd2_m	femoral bone mineral density 2, females only (mouse)					6	75026989	115026943	Mouse
1301320	Ots1_m	ovarian teratoma susceptibility 1 (mouse)			Not determined		6	75424566	104480516	Mouse
10043901	Pfat5_m	predicted fat percentage 5 (mouse)			Not determined		6	75584287	109584431	Mouse
10412208	Cypr4_m	cytokine production 4 (mouse)			Not determined		6	75693484	109693678	Mouse
1357875	Pfat2_m	predicted fat percentage 2 (mouse)			Not determined		6	76440930	110441074	Mouse
4141376	Dbm1_m	diabetes modifier 1 (mouse)			Not determined		6	78606487	121092347	Mouse
14696731	Pairq1_m	P. aeruginosa infection resistance QTL 1 (mouse)					6	81476981	102176961	Mouse
10043864	T2dm4sa_m	type 2 diabetes mellitus 4 in SMXA RI mice (mouse)			Not determined		6	83690851	146954059	Mouse
11251720	Ewc4_m	ethanol withdrawal and consumption 4 (mouse)					6	84099474	118099474	Mouse
1301687	Mnic2_m	macronutrient intake (mouse)			Not determined		6	86783787	113521563	Mouse
1301744	Hdlq11_m	HDL QTL 11 (mouse)			Not determined		6	87480321	121480516	Mouse
1301262	Gasa3_m	gastritis type A susceptibility locus 3 (mouse)			Not determined		6	88982366	122982564	Mouse
1301244	Ichs_m	immediate cutaneous hypersensitivity QTL (mouse)			Not determined		6	90772571	124772807	Mouse
4141578	Obrq1_m	obesity resistance QTL 1 (mouse)			Not determined			92584287	111981699	Mouse
11353842	Bmiq4_m	body mass index QTL 4 (mouse)					6	92584287	146330736	Mouse
1301292	Cfbw2_m	cystic fibrosis body weight 2 (mouse)			Not determined		6	94981612	128981699	Mouse
11040599	Lmr4b_m	leishmaniasis resistance 4b (mouse)					6	96324286	130324483	Mouse
1300704	Cia3_m	collagen induced arthritis QTL 3 (mouse)			Not determined		6	96324286	130324483	Mouse
4141940	W6q5_m	weight 6 weeks QTL 5 (mouse)			Not determined			96632912	146535124	Mouse
4142416	Egq11_m	early growth QTL 11 (mouse)			Not determined			96632912	146535124	Mouse
1357555	Tesq2_m	testis weight QTL 2 (mouse)			Not determined		6	96632912	146535124	Mouse
10043923	Bhr7_m	bronchial hyperresponsiveness 7 (mouse)			Not determined		6	98219814	132219938	Mouse
1301518	Bbaa5_m	B.burgdorferi-associated arthritis 5 (mouse)			Not determined		6	98483798	145881170	Mouse
1301923	Lith6_m	lithogenic gene 6 (mouse)			Not determined		6	98694477	132694676	Mouse
1301915	Chab3_m	cholesterol absorption 3 (mouse)			Not determined		6	98908709	132916997	Mouse
1302131	Bmd8_m	bone mineral density 8 (mouse)			Not determined		6	99132089	133132228	Mouse

Markers in Region

UniSTS:487638

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	99,692,679 - 99,693,818	UniSTS	GRCm38
MGSCv37	6	99,642,673 - 99,643,812	UniSTS	GRCm37
Cytogenetic Map	6	E1	UniSTS

UniSTS:493241

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	99,692,679 - 99,693,818	UniSTS	GRCm38
MGSCv37	6	99,642,673 - 99,643,812	UniSTS	GRCm37
Cytogenetic Map	6	E1	UniSTS

UniSTS:494131

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	99,692,591 - 99,693,859	UniSTS	GRCm38
MGSCv37	6	99,642,585 - 99,643,853	UniSTS	GRCm37
Cytogenetic Map	6	E1	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_008158	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC122929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF027955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX523686	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000101122 ⟹ ENSMUSP00000098680

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	99,669,640 - 99,672,027 (+)	Ensembl
GRCm38.p6 Ensembl	6	99,692,679 - 99,695,066 (+)	Ensembl

RefSeq Acc Id:

NM_008158 ⟹ NP_032184

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	99,669,328 - 99,672,027 (+)	NCBI
GRCm38	6	99,692,367 - 99,695,066 (+)	NCBI
MGSCv37	6	99,642,673 - 99,643,812 (+)	RGD
Celera	6	101,556,765 - 101,557,942 (+)	ENTREZGENE
cM Map	6		ENTREZGENE

Sequence:

show sequence

AGAGCCAAGAGGCGCGGCGGCGGAGGAGGAACGGGAGGAGGACGCGGAGCATGCGGGGGGCTGC
AGGCCTGCCCGCAGTGAAGCCCGCCGCGCCCAGGGCGCAGGGAGTGGCCGTCGCCTCCTGCGCG
CACCGCGACTGAGATGGCGGCGGCGGCGGCGCGGCCGAGGCGCGCCGAGCCCCCGGGGCAGGGC
CGGCCGGGCGCGGGCTGACAACCCCGCGGGCCGGGAGAGCTAGCGTGGAGGAGCGCAGGCCCCG
GGGCGGCCTACGGCGAGCGGCGAGGGCCGGCGGGGAGGAGGAGGAGCACGGCCGCGATGGCGAA
CGCTAGTGAGCCGGGCGGCGGCGGCAGCGGCGGAGGGGCCGAGGCTGCCGCGCTGGGCCTTAGG
CTGGCCACGCTCAGCCTGCTGCTGTGCGTGAGCCTGGCGGGCAACGTGCTGTTCGCGCTGCTCA
TCGTGCGGGAGCGCAGCCTGCACCGCGCGCCGTACTACCTGCTGCTCGACCTGTGCCTGGCCGA
CGGGCTGCGCGCGCTCGCCTGCCTCCCGGCCGTCATGCTGGCGGCGCGGCGCGCGGCGGCCGCG
GCGGGGACGCCGCCGGGCGCGCTGGGCTGCAAGCTGCTGGCCTTCCTGGCCGCACTCTTCTGCT
TCCACGCGGCCTTCCTGCTGCTGGGCGTGGGCGTCACCCGCTACCTGGCCATCGCGCACCACCG
CTTCTACGCCGAGCGCCTGGCCGGCTGGCCGTGCGCCGCGATGCTGGTGTGCGCCGCCTGGGCG
CTGGCTTTGGCCGCGGCCTTCCCGCCGGTGCTGGACGGCGGTGGCGCGGACGACGAGGACGCGC
CGTGCGCCCTGGAGCAGCGACCCGACGGCGCCCCGGGTGCGCTAGGCTTCCTGCTGCTCCTGGC
CGCGGTGGTGGGCGCCACGCACCTCGTCTACCTCCGCCTGCTCTTCTTCATCCACGACCGCCGC
AAGATGCGACCCGCGCGCCTGGTGCCCGCCGTCAGCCACGACTGGACCTTCCACGGCCCGGGCG
CCACCGGTCAGGCGGCCGCCAACTGGACGGCGGGCTTCGGCCGCGGGCCCACGCCACCTGCGCT
CGTGGGCATCAGGCCTGCAGGCCCGGGCCGCGGCGCCCGGCGCCTCCTGGTGCTGGAGGAGTTC
AAGACGGAGAAGAGGCTGTGCAAGATGTTCTACGCCATCACGCTGCTCTTCCTGCTCCTCTGGG
GCCCCTATGTGGTGGCCAGTTACCTGCGCGTCCTGGTGCGCCCGGGAGCTGTCCCGCAGGCCTA
CCTGACAGCCTCGGTGTGGCTGACATTCGCGCAGGCCGGCATCAACCCCGTGGTGTGTTTCCTC
TTCAACCGGGAGCTGAGGGACTGTTTCCGAGCCCAGTTTCCCTGCTGCCAGAGCCCCCAGGCCA
CGCAGGCCACCCTCCCCTGCGACCTGAAAGGCATTGGTTTGTGAAGCGCGCTCTGCCACCCAGG
CTCCCTCTGGCTTCGATTGTGACCGCTCATCTTTCCCTTCTGTCCCGTTGTCTGGTTTTTCTCT
GCTGCCTTCAGGAGACTCTGAAAGTGGACACGCACTTGGATTGTATAGACCCCTGTTCTGGGGC
CGGGGGAGGGATGCTGAGGTCCCGTTCTGTCCTTTAATTATACTTTCTTCCTGACAGTAGGCCC
TGCAGTCTTTTTGTACTGGTACCGACTTCTTTTCTTCCACGTGTGATTTTTTTTTTTTTTTAAA
TAAAGGCTACACTGGTTTTATTCATGCAAAGTTTCCTAGAGACCATGGCCAGTTTTCTACAGAG
GCTATTTTTGACAACCTCAAGTGGCATTACCTTTGCGTTGCAGTGAAGGAGAGCGAGCTAGGAG
ATGTTGGAGATGGAAGAGAGGGACAGAGTTGTCTAAAGTCCCCTCAGAACTGCAGGCCACAGGG
CCAGGTGAGCTGTGTGCCTTGTTTGGGGGGTGTGGGGGACTTCTCCCAGTGGTGACACTGAACT
TTAGGAGAAAATGCGAATGGGTAGGAGGACGGTCTTATTTGAGTCACTTAAGGAGCAAGGTCTG
GGGCCCTGTGTAAGTTATTATAAAACAATGCATCAGCAAACAGCTGCTCTGTAGACCAGTCTTG
GATGGAAACTTTCTGTGAGACTGTGACTTTTAAACAGTAAAAAGTGTTTTGGATAGTAATGTGG
AGAAAAAAAAAACAGTATTGCATGTGTTTGTACCGATTGTGATTTGCGGATGGGGTGGGCTCTG
GAGGGCAGAAAAATACAGGTTTGTTTGGGTTAGGGGTTTGGGGGATTTTCCCCCCCAATAAAAA
GTTAAAATACTTTTGTGGAAATGGCTTGTGCTTTGATAAGCCCAGTTTTACTCTGTATTATGAG
CTAATTTTCCCTCTGAAGACTTGTCTGTGGTTAAGAAGATATGGGATATAACGGTGCCTCTCCC
AGGAGACAAGCATTTTCCTGCGGTGTTTGCTAAGTTAGGTGGTGCTGTTCTACTCATGGCTGTT
TTCAATGATTAATAAGAAACCATAATTTAAAATACGATCTCTTTGTTAGACATTGTCACTTGAC
ACCGAAGGACTTCATTGCAAGTACTGTATAATACTTTTTGCTTAAACTGCTCTGTTTTTATTAA
TGTAACTTGCGTTTTGAAGATTTCTATCTGTACTTCTCTTTGCATTACACAAATATACCAGTAT
TTTCACTCTGGAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_032184	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC53540	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000098680
	ENSMUSP00000098680.2
GenBank Protein	O54897	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_032184 ⟸ NM_008158

- UniProtKB:

O54897 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MANASEPGGGGSGGGAEAAALGLRLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLC
LADGLRALACLPAVMLAARRAAAAAGTPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIA
HHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGADDEDAPCALEQRPDGAPGALGFLL
LLAAVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTP
PALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAITLLFLLLWGPYVVASYLRVLVRPGAVP
QAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPQATQATLPCDLKGIGL

hide sequence

RefSeq Acc Id:

ENSMUSP00000098680 ⟸ ENSMUST00000101122

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O54897-F1-model_v2	AlphaFold	O54897	1-379	view protein structure

Promoters

RGD ID:

6839412

Promoter ID:

MM_KWN:47045

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain, Lung

Transcripts:

NM_008158

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	99,641,881 - 99,643,657 (+)	MPROMDB

RGD ID:

6890542

Promoter ID:

EPDNEW_M8722

Type:

multiple initiation site

Name:

Gpr27_1

Description:

Mus musculus G protein-coupled receptor 27 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	99,692,594 - 99,692,654	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1202299	AgrOrtholog
Ensembl Genes	ENSMUSG00000072875	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000101122	ENTREZGENE
	ENSMUST00000101122.3	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot
KEGG Report	mmu:14761	UniProtKB/Swiss-Prot
MGD	MGI:1202299	ENTREZGENE
NCBI Gene	14761	ENTREZGENE
PANTHER	G PROTEIN-COUPLED RECEPTOR	UniProtKB/Swiss-Prot
	G-PROTEIN COUPLED RECEPTOR 27-RELATED	UniProtKB/Swiss-Prot
Pfam	7tm_1	UniProtKB/Swiss-Prot
PhenoGen	Gpr27	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot
PROSITE	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot
UniProt	GPR27_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Mammalian Phenotype