Apba2 (amyloid beta precursor protein binding family A member 2) - Rat Genome Database

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Gene: Apba2 (amyloid beta precursor protein binding family A member 2) Mus musculus
Analyze
Symbol: Apba2
Name: amyloid beta precursor protein binding family A member 2 (Ensembl:amyloid beta (A4) precursor protein-binding, family A, member 2)
RGD ID: 733397
MGI Page MGI
Description: Predicted to enable amyloid-beta binding activity and identical protein binding activity. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within several processes, including chemical synaptic transmission; in utero embryonic development; and locomotory behavior. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and skeleton. Orthologous to human APBA2 (amyloid beta precursor protein binding family A member 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adapter protein X11beta; amyloid beta (A4) precursor protein-binding, family A, member 2; amyloid beta A4 precursor protein-binding family A member 2; amyloid-beta A4 precursor protein-binding family A member 2; Mint 2; mint-2; mXllL; neuron-specific X11L protein; neuronal Munc18-1-interacting protein 2; X11; X11-li; X11-like; X11L; XllL
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39764,151,444 - 64,403,620 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl764,151,454 - 64,403,626 (+)EnsemblGRCm39 Ensembl
GRCm38764,501,560 - 64,753,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl764,501,706 - 64,753,878 (+)EnsemblGRCm38mm10GRCm38
MGSCv37771,646,592 - 71,898,764 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36764,380,656 - 64,632,820 (+)NCBIMGSCv36mm8
Celera761,926,576 - 62,168,071 (+)NCBICelera
Cytogenetic Map7CNCBI
cM Map734.65NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7678331   PMID:7719031   PMID:8889548   PMID:9585438   PMID:9890987   PMID:10349636   PMID:10833507   PMID:11042159   PMID:11076861   PMID:11083918   PMID:11217851   PMID:11517249  
PMID:12466851   PMID:12477932   PMID:12547917   PMID:12828934   PMID:14681479   PMID:15345747   PMID:15347685   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16280085   PMID:16906128  
PMID:17032642   PMID:17167098   PMID:18201694   PMID:18650433   PMID:18845544   PMID:19118172   PMID:19420255   PMID:20925061   PMID:21267068   PMID:21873635   PMID:24742670   PMID:24952961  
PMID:27268412   PMID:30411795   PMID:30988517   PMID:34321999   PMID:36417873  


Genomics

Comparative Map Data
Apba2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39764,151,444 - 64,403,620 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl764,151,454 - 64,403,626 (+)EnsemblGRCm39 Ensembl
GRCm38764,501,560 - 64,753,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl764,501,706 - 64,753,878 (+)EnsemblGRCm38mm10GRCm38
MGSCv37771,646,592 - 71,898,764 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36764,380,656 - 64,632,820 (+)NCBIMGSCv36mm8
Celera761,926,576 - 62,168,071 (+)NCBICelera
Cytogenetic Map7CNCBI
cM Map734.65NCBI
APBA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381528,885,974 - 29,118,315 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1528,884,483 - 29,118,315 (+)EnsemblGRCh38hg38GRCh38
GRCh371529,131,120 - 29,410,518 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361527,001,145 - 27,197,807 (+)NCBINCBI36Build 36hg18NCBI36
Build 341527,001,144 - 27,197,807NCBI
Celera156,851,376 - 7,048,205 (+)NCBICelera
Cytogenetic Map15q13.1NCBI
HuRef156,871,147 - 7,068,137 (+)NCBIHuRef
CHM1_11529,179,947 - 29,376,717 (+)NCBICHM1_1
T2T-CHM13v2.01526,662,979 - 26,895,835 (+)NCBIT2T-CHM13v2.0
Apba2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81127,465,026 - 127,698,124 (+)NCBIGRCr8
mRatBN7.21118,053,270 - 118,286,858 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1118,103,219 - 118,285,699 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1126,078,601 - 126,266,079 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01133,261,175 - 133,448,662 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01126,092,984 - 126,281,269 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01125,367,273 - 125,547,741 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1125,367,280 - 125,548,890 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01126,475,693 - 126,655,820 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41118,970,882 - 119,156,605 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11119,049,224 - 119,234,941 (+)NCBI
Celera1110,357,368 - 110,535,519 (+)NCBICelera
Cytogenetic Map1q22NCBI
Apba2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541629,390,362 - 29,581,094 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541629,390,601 - 29,591,815 (-)NCBIChiLan1.0ChiLan1.0
APBA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2165,540,128 - 5,773,061 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1159,184,588 - 9,417,623 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v015167,863 - 400,296 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11527,177,289 - 27,410,125 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1527,174,217 - 27,241,529 (-)Ensemblpanpan1.1panPan2
APBA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1338,243,086 - 38,431,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl338,243,102 - 38,430,887 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha340,933,480 - 41,121,526 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0338,619,916 - 38,808,008 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl338,569,163 - 38,808,005 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1338,145,441 - 38,333,103 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0338,405,501 - 38,593,510 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0338,613,084 - 38,801,083 (+)NCBIUU_Cfam_GSD_1.0
Apba2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640145,019,424 - 145,271,524 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364831,250,152 - 1,315,088 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364831,062,971 - 1,315,059 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APBA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1144,071,859 - 144,315,151 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11144,183,148 - 144,315,154 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21160,380,931 - 160,397,178 (+)NCBISscrofa10.2Sscrofa10.2susScr3
APBA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12651,990,492 - 52,053,198 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2651,990,534 - 52,051,986 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604888,763,323 - 88,993,823 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Apba2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247682,207,238 - 2,276,747 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247682,037,866 - 2,276,498 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Apba2
9032 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1004
Count of miRNA genes:400
Interacting mature miRNAs:476
Transcripts:ENSMUST00000032732, ENSMUST00000096173, ENSMUST00000107507, ENSMUST00000137732, ENSMUST00000138829
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301175Ap7q_malcohol preference 7 QTL (mouse)Not determined73171484565715077Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
25314301Vmm3_mvariable multisystem mineralization 3, lung (mouse)73729942572049748Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1300878Skts1_mskin tumor susceptibility 1 (mouse)Not determined73789138671891582Mouse
10402488Dipa2_mdrug induced psychomotor activation 2 (mouse)Not determined73842154872421684Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
12880417V125Dq5_mvitamin D active form serum level QTL 5 (mouse)74524974879249748Mouse
25314302Vmm2_mvariable multisystem mineralization 2, heart (mouse)74714974874149748Mouse
12738423Lfibq6_mliver fibrosis QTL 6 (mouse)74769437866704862Mouse
1302141Fcsa6_mfemoral cross-sectional area 6 (mouse)Not determined74838446182384607Mouse
11532741Tbrs5_mtuberculosis resistance 5 (mouse)74915922783235415Mouse
1357752Tabw_mtally ho asscoiated body weight (mouse)Not determined74919327883193390Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75112495485125093Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75112495485125093Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75214974886149748Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75588950887142720Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
1300952Hcs1_mhepatocarcinogenesis susceptibility 1 (mouse)Not determined75732612191326352Mouse
1301465Egrm3_mearly growth rate (mouse)Not determined75732612191326352Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75732612191326352Mouse
13432171Rosd1_mrotarod saline difference 1 (mouse)75919437869004862Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
13506761Tbthq1_mtrabecular bone thickness QTL 1 (mouse)76234974867749748Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76413542498135653Mouse

Markers in Region
D7Mit298  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38764,565,835 - 64,565,941UniSTSGRCm38
MGSCv37771,710,721 - 71,710,827UniSTSGRCm37
Celera761,992,630 - 61,992,732UniSTS
Cytogenetic Map7CUniSTS
cM Map727.0UniSTS
Whitehead Genetic726.2UniSTS
Whitehead_YAC7 UniSTS
L34676  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38764,753,171 - 64,753,296UniSTSGRCm38
MGSCv37771,898,057 - 71,898,182UniSTSGRCm37
Celera762,167,364 - 62,167,489UniSTS
Cytogenetic Map7CUniSTS
cM Map725.5UniSTS
Apba2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37771,859,352 - 71,860,419UniSTSGRCm37
Celera762,128,765 - 62,129,832UniSTS
Cytogenetic Map7CUniSTS
cM Map725.5UniSTS
cM Map725.5UniSTS
Apba2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38764,714,466 - 64,715,533UniSTSGRCm38
MGSCv37771,859,352 - 71,860,419UniSTSGRCm37
Celera762,128,765 - 62,129,832UniSTS
Cytogenetic Map7CUniSTS
cM Map725.5UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001291166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001411946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB014720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC127306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC129199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC140297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE985957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB525662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK619036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L34676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000032732   ⟹   ENSMUSP00000032732
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl764,151,454 - 64,403,626 (+)Ensembl
GRCm38.p6 Ensembl764,501,706 - 64,753,878 (+)Ensembl
RefSeq Acc Id: ENSMUST00000205551
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl764,379,150 - 64,394,266 (+)Ensembl
GRCm38.p6 Ensembl764,729,402 - 64,744,518 (+)Ensembl
RefSeq Acc Id: ENSMUST00000205604   ⟹   ENSMUSP00000146279
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl764,151,886 - 64,345,119 (+)Ensembl
GRCm38.p6 Ensembl764,502,138 - 64,695,371 (+)Ensembl
RefSeq Acc Id: ENSMUST00000205613   ⟹   ENSMUSP00000146269
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl764,151,697 - 64,345,055 (+)Ensembl
GRCm38.p6 Ensembl764,501,949 - 64,695,307 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206061
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl764,393,587 - 64,403,114 (+)Ensembl
GRCm38.p6 Ensembl764,743,839 - 64,753,366 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206246   ⟹   ENSMUSP00000146038
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl764,284,779 - 64,403,606 (+)Ensembl
GRCm38.p6 Ensembl764,635,031 - 64,753,858 (+)Ensembl
RefSeq Acc Id: ENSMUST00000206630   ⟹   ENSMUSP00000146108
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl764,394,331 - 64,403,153 (+)Ensembl
GRCm38.p6 Ensembl764,744,583 - 64,753,405 (+)Ensembl
RefSeq Acc Id: NM_001291166   ⟹   NP_001278095
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
GRCm38764,502,138 - 64,753,878 (+)NCBI
Celera761,926,576 - 62,168,071 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291167   ⟹   NP_001278096
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
GRCm38764,502,138 - 64,753,878 (+)NCBI
Celera761,926,576 - 62,168,071 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001411931   ⟹   NP_001398860
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,444 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411932   ⟹   NP_001398861
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,444 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411933   ⟹   NP_001398862
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411934   ⟹   NP_001398863
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411935   ⟹   NP_001398864
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,444 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411936   ⟹   NP_001398865
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411937   ⟹   NP_001398866
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,444 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411938   ⟹   NP_001398867
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411939   ⟹   NP_001398868
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411940   ⟹   NP_001398869
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411941   ⟹   NP_001398870
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411942   ⟹   NP_001398871
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411943   ⟹   NP_001398872
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,444 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411944   ⟹   NP_001398873
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411945   ⟹   NP_001398874
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,885 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_001411946   ⟹   NP_001398875
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,444 - 64,403,618 (+)NCBI
RefSeq Acc Id: NM_007461   ⟹   NP_031487
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,444 - 64,403,618 (+)NCBI
GRCm38764,501,706 - 64,753,878 (+)NCBI
MGSCv37771,646,592 - 71,898,764 (+)RGD
Celera761,926,576 - 62,168,071 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030242009   ⟹   XP_030097869
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,202,941 - 64,403,620 (+)NCBI
GRCm38764,553,193 - 64,753,872 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030242011   ⟹   XP_030097871
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,741 - 64,403,618 (+)NCBI
GRCm38764,502,047 - 64,753,870 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152585   ⟹   XP_036008478
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,741 - 64,403,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152586   ⟹   XP_036008479
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,616 - 64,403,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152587   ⟹   XP_036008480
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,151,484 - 64,403,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152588   ⟹   XP_036008481
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39764,202,936 - 64,403,620 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001278095 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278096 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398860 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398861 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398862 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398863 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398864 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398865 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398866 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398867 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398868 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398869 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398870 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398871 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398872 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398873 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398874 (Get FASTA)   NCBI Sequence Viewer  
  NP_001398875 (Get FASTA)   NCBI Sequence Viewer  
  NP_031487 (Get FASTA)   NCBI Sequence Viewer  
  XP_030097869 (Get FASTA)   NCBI Sequence Viewer  
  XP_030097871 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008478 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008479 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008480 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008481 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA73936 (Get FASTA)   NCBI Sequence Viewer  
  AAH57620 (Get FASTA)   NCBI Sequence Viewer  
  AAH60269 (Get FASTA)   NCBI Sequence Viewer  
  BAA34735 (Get FASTA)   NCBI Sequence Viewer  
  BAE34588 (Get FASTA)   NCBI Sequence Viewer  
  EDL07250 (Get FASTA)   NCBI Sequence Viewer  
  EDL07251 (Get FASTA)   NCBI Sequence Viewer  
  EDL07252 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000032732
  ENSMUSP00000032732.9
  ENSMUSP00000146038
  ENSMUSP00000146038.2
  ENSMUSP00000146108.2
  ENSMUSP00000146269.2
  ENSMUSP00000146279.2
GenBank Protein P98084 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_031487   ⟸   NM_007461
- Peptide Label: isoform a
- UniProtKB: Q6PAJ2 (UniProtKB/Swiss-Prot),   P98084 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001278095   ⟸   NM_001291166
- Peptide Label: isoform a
- UniProtKB: Q6PAJ2 (UniProtKB/Swiss-Prot),   P98084 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001278096   ⟸   NM_001291167
- Peptide Label: isoform a
- UniProtKB: Q6PAJ2 (UniProtKB/Swiss-Prot),   P98084 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030097871   ⟸   XM_030242011
- Peptide Label: isoform X1
- UniProtKB: P98084 (UniProtKB/Swiss-Prot),   Q6PAJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_030097869   ⟸   XM_030242009
- Peptide Label: isoform X1
- UniProtKB: P98084 (UniProtKB/Swiss-Prot),   Q6PAJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSMUSP00000032732   ⟸   ENSMUST00000032732
RefSeq Acc Id: ENSMUSP00000146108   ⟸   ENSMUST00000206630
RefSeq Acc Id: ENSMUSP00000146038   ⟸   ENSMUST00000206246
RefSeq Acc Id: ENSMUSP00000146269   ⟸   ENSMUST00000205613
RefSeq Acc Id: ENSMUSP00000146279   ⟸   ENSMUST00000205604
RefSeq Acc Id: XP_036008480   ⟸   XM_036152587
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036008479   ⟸   XM_036152586
- Peptide Label: isoform X1
- UniProtKB: P98084 (UniProtKB/Swiss-Prot),   Q6PAJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_036008478   ⟸   XM_036152585
- Peptide Label: isoform X1
- UniProtKB: P98084 (UniProtKB/Swiss-Prot),   Q6PAJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_036008481   ⟸   XM_036152588
- Peptide Label: isoform X2
- UniProtKB: A0A0U1RPM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001398864   ⟸   NM_001411935
- Peptide Label: isoform a
- UniProtKB: P98084 (UniProtKB/Swiss-Prot),   Q6PAJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001398860   ⟸   NM_001411931
- Peptide Label: isoform a
- UniProtKB: P98084 (UniProtKB/Swiss-Prot),   Q6PAJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001398872   ⟸   NM_001411943
- Peptide Label: isoform c
RefSeq Acc Id: NP_001398866   ⟸   NM_001411937
- Peptide Label: isoform b
- UniProtKB: A0A0U1RPM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001398875   ⟸   NM_001411946
- Peptide Label: isoform d
RefSeq Acc Id: NP_001398861   ⟸   NM_001411932
- Peptide Label: isoform a
- UniProtKB: P98084 (UniProtKB/Swiss-Prot),   Q6PAJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001398863   ⟸   NM_001411934
- Peptide Label: isoform a
- UniProtKB: P98084 (UniProtKB/Swiss-Prot),   Q6PAJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001398870   ⟸   NM_001411941
- Peptide Label: isoform b
- UniProtKB: A0A0U1RPM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001398868   ⟸   NM_001411939
- Peptide Label: isoform b
- UniProtKB: A0A0U1RPM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001398862   ⟸   NM_001411933
- Peptide Label: isoform a
- UniProtKB: P98084 (UniProtKB/Swiss-Prot),   Q6PAJ2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001398873   ⟸   NM_001411944
- Peptide Label: isoform c
RefSeq Acc Id: NP_001398869   ⟸   NM_001411940
- Peptide Label: isoform b
- UniProtKB: A0A0U1RPM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001398871   ⟸   NM_001411942
- Peptide Label: isoform c
RefSeq Acc Id: NP_001398865   ⟸   NM_001411936
- Peptide Label: isoform b
- UniProtKB: A0A0U1RPM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001398874   ⟸   NM_001411945
- Peptide Label: isoform d
RefSeq Acc Id: NP_001398867   ⟸   NM_001411938
- Peptide Label: isoform b
- UniProtKB: A0A0U1RPM0 (UniProtKB/TrEMBL)
Protein Domains
PDZ   PID

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P98084-F1-model_v2 AlphaFold P98084 1-750 view protein structure

Promoters
RGD ID:8664353
Promoter ID:EPDNEW_M10207
Type:initiation region
Name:Apba2_2
Description:Mus musculus amyloid beta precursor protein-binding, family A,member 2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10208  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38764,501,696 - 64,501,756EPDNEW
RGD ID:8664355
Promoter ID:EPDNEW_M10208
Type:multiple initiation site
Name:Apba2_1
Description:Mus musculus amyloid beta precursor protein-binding, family A,member 2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10207  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38764,680,789 - 64,680,849EPDNEW
RGD ID:6840611
Promoter ID:MM_KWN:50915
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_007461,   OTTMUST00000057324,   OTTMUST00000057325
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36771,646,566 - 71,647,066 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1261791 AgrOrtholog
Ensembl Genes ENSMUSG00000030519 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032732 ENTREZGENE
  ENSMUST00000032732.15 UniProtKB/Swiss-Prot
  ENSMUST00000205604.2 UniProtKB/TrEMBL
  ENSMUST00000205613.2 UniProtKB/TrEMBL
  ENSMUST00000206246 ENTREZGENE
  ENSMUST00000206246.2 UniProtKB/TrEMBL
  ENSMUST00000206630.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11784 UniProtKB/Swiss-Prot
MGD MGI:1261791 ENTREZGENE
NCBI Gene 11784 ENTREZGENE
PANTHER PTHR12345:SF12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SYNTENIN RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PID UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Apba2 PhenoGen
PROSITE PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PID UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0U1RPM0 ENTREZGENE, UniProtKB/TrEMBL
  A0A0U1RPS9_MOUSE UniProtKB/TrEMBL
  A0A0U1RQ68_MOUSE UniProtKB/TrEMBL
  A0A0U1RQ78_MOUSE UniProtKB/TrEMBL
  APBA2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TYH5_MOUSE UniProtKB/TrEMBL
  Q6PAJ2 ENTREZGENE
  Q9Z316_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q6PAJ2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Apba2  amyloid beta precursor protein binding family A member 2  Apba2  amyloid beta (A4) precursor protein-binding, family A, member 2  Symbol and/or name change 5135510 APPROVED