CACNG1 (calcium voltage-gated channel auxiliary subunit gamma 1) - Rat Genome Database

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Gene: CACNG1 (calcium voltage-gated channel auxiliary subunit gamma 1) Homo sapiens
Analyze
Symbol: CACNG1
Name: calcium voltage-gated channel auxiliary subunit gamma 1
RGD ID: 732630
HGNC Page HGNC:1405
Description: Predicted to enable calcium channel regulator activity. Predicted to be involved in regulation of calcium ion transmembrane transport via high voltage-gated calcium channel. Predicted to act upstream of or within calcium ion transmembrane transport; establishment of localization in cell; and sarcoplasmic reticulum calcium ion transport. Predicted to be located in T-tubule. Predicted to be part of L-type voltage-gated calcium channel complex. Implicated in malignant hyperthermia.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CACNLG; calcium channel, voltage-dependent, gamma subunit 1; dihydropyridine-sensitive L-type skeletal muscle calcium channel gamma subunit; dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma; L-type calcium channel gamma polypeptide; neuronal dihydropyridine-sensitive calcium channel gamma subunit; voltage-dependent calcium channel gamma-1 subunit
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381767,044,554 - 67,056,797 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1767,044,554 - 67,056,797 (+)EnsemblGRCh38hg38GRCh38
GRCh371765,040,670 - 65,052,913 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361762,471,168 - 62,483,375 (+)NCBINCBI36Build 36hg18NCBI36
Build 341762,471,167 - 62,483,371NCBI
Celera1761,613,382 - 61,625,583 (+)NCBICelera
Cytogenetic Map17q24.2NCBI
HuRef1760,429,261 - 60,441,513 (+)NCBIHuRef
CHM1_11765,104,606 - 65,116,856 (+)NCBICHM1_1
T2T-CHM13v2.01767,920,364 - 67,932,598 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Genetic mapping of the beta 1- and gamma-subunits of the human skeletal muscle L-type voltage-dependent calcium channel on chromosome 17q and exclusion as candidate genes for malignant hyperthermia susceptibility. Iles DE, etal., Hum Mol Genet 1993 Jul;2(7):863-8.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8111396   PMID:8387489   PMID:8404045   PMID:9186513   PMID:10613843   PMID:11170751   PMID:11738816   PMID:12477932   PMID:15489334   PMID:16344560   PMID:17652770   PMID:18187620  
PMID:21873635   PMID:22982493   PMID:24623722   PMID:25416956   PMID:27273705   PMID:29987050   PMID:31615875   PMID:32296183   PMID:33961781  


Genomics

Comparative Map Data
CACNG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381767,044,554 - 67,056,797 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1767,044,554 - 67,056,797 (+)EnsemblGRCh38hg38GRCh38
GRCh371765,040,670 - 65,052,913 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361762,471,168 - 62,483,375 (+)NCBINCBI36Build 36hg18NCBI36
Build 341762,471,167 - 62,483,371NCBI
Celera1761,613,382 - 61,625,583 (+)NCBICelera
Cytogenetic Map17q24.2NCBI
HuRef1760,429,261 - 60,441,513 (+)NCBIHuRef
CHM1_11765,104,606 - 65,116,856 (+)NCBICHM1_1
T2T-CHM13v2.01767,920,364 - 67,932,598 (+)NCBIT2T-CHM13v2.0
Cacng1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911107,594,044 - 107,607,302 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11107,594,044 - 107,607,348 (-)EnsemblGRCm39 Ensembl
GRCm3811107,703,218 - 107,716,476 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11107,703,218 - 107,716,522 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711107,564,532 - 107,577,790 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611107,519,308 - 107,532,566 (-)NCBIMGSCv36mm8
Celera11119,438,411 - 119,451,651 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1170.29NCBI
Cacng1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81093,152,558 - 93,165,246 (-)NCBIGRCr8
mRatBN7.21092,652,924 - 92,665,612 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1092,652,614 - 92,665,783 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1097,711,022 - 97,723,710 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01097,174,042 - 97,186,732 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01092,575,656 - 92,588,362 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01095,921,479 - 95,934,170 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1095,921,174 - 95,934,345 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01095,655,624 - 95,668,315 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41097,105,707 - 97,118,400 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11097,120,076 - 97,132,770 (-)NCBI
Celera1091,318,721 - 91,331,399 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Cacng1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554786,294,974 - 6,305,669 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554786,295,046 - 6,305,625 (+)NCBIChiLan1.0ChiLan1.0
CACNG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21983,071,599 - 83,090,853 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11787,891,441 - 87,914,656 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01760,978,895 - 60,993,621 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11766,187,565 - 66,199,795 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1766,187,565 - 66,199,789 (+)Ensemblpanpan1.1panPan2
CACNG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1913,425,898 - 13,438,275 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl913,426,105 - 13,438,614 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha914,320,527 - 14,332,878 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0915,088,975 - 15,101,463 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl915,089,182 - 15,101,509 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1914,036,391 - 14,048,856 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0913,485,243 - 13,497,697 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0913,486,979 - 13,499,379 (+)NCBIUU_Cfam_GSD_1.0
Cacng1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560213,154,750 - 13,165,862 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365416,028,669 - 6,040,034 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365416,028,775 - 6,039,882 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CACNG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1213,463,058 - 13,481,645 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11213,462,589 - 13,481,651 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21213,833,206 - 13,844,295 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CACNG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11654,383,328 - 54,397,331 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1654,383,204 - 54,396,610 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607725,422,067 - 25,435,899 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cacng1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248701,333,843 - 1,344,483 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248701,333,907 - 1,344,386 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CACNG1
11 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2		 pathogenic
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3		 pathogenic
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1		 pathogenic
GRCh38/hg38 17q24.1-24.2(chr17:64634771-67686888)x1 copy number loss See cases [RCV000140815] Chr17:64634771..67686888 [GRCh38]
Chr17:62649313..65683004 [GRCh37]
Chr17:60061351..63113466 [NCBI36]
Chr17:17q24.1-24.2		 pathogenic
GRCh37/hg19 17q24.2-25.3(chr17:64241326-81041938)x3 copy number gain See cases [RCV000447577] Chr17:64241326..81041938 [GRCh37]
Chr17:17q24.2-25.3		 pathogenic
GRCh37/hg19 17q21.31-25.3(chr17:42580684-81085615)x3 copy number gain See cases [RCV000447823] Chr17:42580684..81085615 [GRCh37]
Chr17:17q21.31-25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17q24.2(chr17:64963389-65726146)x3 copy number gain not provided [RCV000683953] Chr17:64963389..65726146 [GRCh37]
Chr17:17q24.2		 uncertain significance
GRCh37/hg19 17q24.1-25.3(chr17:63689671-81041938)x3 copy number gain not provided [RCV000683952] Chr17:63689671..81041938 [GRCh37]
Chr17:17q24.1-25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17q24.1-25.2(chr17:64159738-74891024)x3 copy number gain not provided [RCV000762750] Chr17:64159738..74891024 [GRCh37]
Chr17:17q24.1-25.2		 likely pathogenic
GRCh37/hg19 17q22-24.2(chr17:57357088-66306668) copy number gain not provided [RCV000767764] Chr17:57357088..66306668 [GRCh37]
Chr17:17q22-24.2		 pathogenic
GRCh37/hg19 17q24.1-25.3(chr17:62778720-81041938)x3 copy number gain not provided [RCV000849900] Chr17:62778720..81041938 [GRCh37]
Chr17:17q24.1-25.3		 pathogenic
GRCh37/hg19 17q24.2(chr17:65050304-65440440)x3 copy number gain not provided [RCV001006912] Chr17:65050304..65440440 [GRCh37]
Chr17:17q24.2		 uncertain significance
GRCh37/hg19 17q23.1-24.2(chr17:57869604-67078443)x3 copy number gain not provided [RCV000845965] Chr17:57869604..67078443 [GRCh37]
Chr17:17q23.1-24.2		 pathogenic
NM_000727.4(CACNG1):c.331G>A (p.Ala111Thr) single nucleotide variant not specified [RCV004297544] Chr17:67055129 [GRCh38]
Chr17:65051245 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.380T>C (p.Leu127Pro) single nucleotide variant not specified [RCV004132418] Chr17:67055178 [GRCh38]
Chr17:65051294 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.29G>A (p.Arg10His) single nucleotide variant not specified [RCV004071517] Chr17:67044689 [GRCh38]
Chr17:65040805 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.53C>A (p.Ala18Glu) single nucleotide variant not specified [RCV004120881] Chr17:67044713 [GRCh38]
Chr17:65040829 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.325G>A (p.Ala109Thr) single nucleotide variant not specified [RCV004095594] Chr17:67055123 [GRCh38]
Chr17:65051239 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.461C>G (p.Ser154Trp) single nucleotide variant not specified [RCV004130477] Chr17:67056063 [GRCh38]
Chr17:65052179 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.265G>A (p.Gly89Ser) single nucleotide variant not specified [RCV004229453] Chr17:67054031 [GRCh38]
Chr17:65050147 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.389G>A (p.Gly130Glu) single nucleotide variant not specified [RCV004273886] Chr17:67055187 [GRCh38]
Chr17:65051303 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.79G>A (p.Val27Met) single nucleotide variant not specified [RCV004266657] Chr17:67044739 [GRCh38]
Chr17:65040855 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.34A>C (p.Thr12Pro) single nucleotide variant not specified [RCV004290126] Chr17:67044694 [GRCh38]
Chr17:65040810 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.31G>A (p.Val11Met) single nucleotide variant not specified [RCV004432369] Chr17:67044691 [GRCh38]
Chr17:65040807 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.388G>A (p.Gly130Arg) single nucleotide variant not specified [RCV004432370] Chr17:67055186 [GRCh38]
Chr17:65051302 [GRCh37]
Chr17:17q24.2		 likely benign
NM_000727.4(CACNG1):c.68C>T (p.Ala23Val) single nucleotide variant not specified [RCV004432372] Chr17:67044728 [GRCh38]
Chr17:65040844 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.452T>A (p.Ile151Asn) single nucleotide variant not specified [RCV004432371] Chr17:67056054 [GRCh38]
Chr17:65052170 [GRCh37]
Chr17:17q24.2		 uncertain significance
NM_000727.4(CACNG1):c.214A>G (p.Ile72Val) single nucleotide variant not specified [RCV004432368] Chr17:67044874 [GRCh38]
Chr17:65040990 [GRCh37]
Chr17:17q24.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:471
Count of miRNA genes:329
Interacting mature miRNAs:351
Transcripts:ENST00000226021
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
GDB:235907  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371765,050,648 - 65,051,172UniSTSGRCh37
Build 361762,481,110 - 62,481,634RGDNCBI36
Celera1761,623,324 - 61,623,842RGD
Cytogenetic Map17q24UniSTS
HuRef1760,439,254 - 60,439,772UniSTS
GDB:250204  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371765,052,097 - 65,052,419UniSTSGRCh37
Build 361762,482,559 - 62,482,881RGDNCBI36
Celera1761,624,767 - 61,625,089RGD
Cytogenetic Map17q24UniSTS
HuRef1760,440,697 - 60,441,019UniSTS
CACNG1__2503  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371765,052,244 - 65,052,916UniSTSGRCh37
Build 361762,482,706 - 62,483,378RGDNCBI36
Celera1761,624,914 - 61,625,586RGD
HuRef1760,440,844 - 60,441,516UniSTS
SHGC-12505  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371765,052,415 - 65,052,741UniSTSGRCh37
Build 361762,482,877 - 62,483,203RGDNCBI36
Celera1761,625,085 - 61,625,411RGD
Cytogenetic Map17q24UniSTS
HuRef1760,441,015 - 60,441,341UniSTS
Stanford-G3 RH Map172888.0UniSTS
Whitehead-YAC Contig Map17 UniSTS
NCBI RH Map17705.3UniSTS
GeneMap99-G3 RH Map173389.0UniSTS
RH17604  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371765,052,756 - 65,052,889UniSTSGRCh37
Build 361762,483,218 - 62,483,351RGDNCBI36
Celera1761,625,426 - 61,625,559RGD
Cytogenetic Map17q24UniSTS
HuRef1760,441,356 - 60,441,489UniSTS
GeneMap99-GB4 RH Map17421.06UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 3 12 6 17 9 811 816 5 11 4 17 811
Low 55 98 264 73 86 17 128 32 1618 8 249 180 61 34 90
Below cutoff 1431 1620 713 214 814 153 2033 822 1671 104 747 891 64 694 1191 3

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000226021   ⟹   ENSP00000226021
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1767,044,554 - 67,056,797 (+)Ensembl
RefSeq Acc Id: NM_000727   ⟹   NP_000718
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381767,044,554 - 67,056,797 (+)NCBI
GRCh371765,040,652 - 65,052,913 (+)ENTREZGENE
Build 361762,471,168 - 62,483,375 (+)NCBI Archive
Celera1761,613,382 - 61,625,583 (+)RGD
HuRef1760,429,261 - 60,441,513 (+)ENTREZGENE
CHM1_11765,104,606 - 65,116,856 (+)NCBI
T2T-CHM13v2.01767,920,364 - 67,932,598 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_000718   ⟸   NM_000727
- UniProtKB: B2R9N3 (UniProtKB/Swiss-Prot),   Q14D59 (UniProtKB/Swiss-Prot),   Q06432 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000226021   ⟸   ENST00000226021

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q06432-F1-model_v2 AlphaFold Q06432 1-222 view protein structure

Promoters
RGD ID:7236075
Promoter ID:EPDNEW_H23784
Type:initiation region
Name:CACNG1_2
Description:calcium voltage-gated channel auxiliary subunit gamma 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23785  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381767,044,475 - 67,044,535EPDNEW
RGD ID:7236083
Promoter ID:EPDNEW_H23785
Type:initiation region
Name:CACNG1_1
Description:calcium voltage-gated channel auxiliary subunit gamma 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23784  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381767,044,599 - 67,044,659EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1405 AgrOrtholog
COSMIC CACNG1 COSMIC
Ensembl Genes ENSG00000108878 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000226021 ENTREZGENE
  ENST00000226021.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.140.150 UniProtKB/Swiss-Prot
GTEx ENSG00000108878 GTEx
HGNC ID HGNC:1405 ENTREZGENE
Human Proteome Map CACNG1 Human Proteome Map
InterPro PMP22/EMP/MP20/Claudin UniProtKB/Swiss-Prot
  VDCC_g1su UniProtKB/Swiss-Prot
  VDCC_gsu UniProtKB/Swiss-Prot
KEGG Report hsa:786 UniProtKB/Swiss-Prot
NCBI Gene 786 ENTREZGENE
OMIM 114209 OMIM
PANTHER VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT UniProtKB/Swiss-Prot
  VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED UniProtKB/Swiss-Prot
Pfam Claudin_2 UniProtKB/Swiss-Prot
PharmGKB PA26015 PharmGKB
PRINTS VDCCGAMMA UniProtKB/Swiss-Prot
  VDCCGAMMA1 UniProtKB/Swiss-Prot
UniProt B2R9N3 ENTREZGENE
  CCG1_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q14D59 ENTREZGENE
UniProt Secondary B2R9N3 UniProtKB/Swiss-Prot
  Q14D59 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-10 CACNG1  calcium voltage-gated channel auxiliary subunit gamma 1    calcium channel, voltage-dependent, gamma subunit 1  Symbol and/or name change 5135510 APPROVED