Krtap12-23 (keratin associated protein 12-23) - Rat Genome Database

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Gene: Krtap12-23 (keratin associated protein 12-23) Mus musculus
Analyze
Symbol: Krtap12-23 (Ensembl: Gm10272)
Name: keratin associated protein 12-23 (Ensembl:predicted gene 10272)
RGD ID: 5144850
MGI Page MGI
Description: Predicted to enable identical protein binding activity. Orthologous to several human genes including KRTAP12-2 (keratin associated protein 12-2); INTERACTS WITH aflatoxin B1 (ortholog); benzo[a]pyrene (ortholog); CGP 52608 (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ENSMUSG00000069584; Gm10272; keratin associated protein 12-4; keratin associated protein LOC16697; Keratin-associated protein 12-1; Krtap12-4
RGD Orthologs
Human
Bonobo
Dog
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391077,542,423 - 77,542,820 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1077,542,460 - 77,542,809 (+)EnsemblGRCm39 Ensembl
GRCm381077,706,589 - 77,706,986 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1077,706,626 - 77,706,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv371077,169,332 - 77,169,731 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1078,750,471 - 78,750,870 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9878246  


Genomics

Comparative Map Data
Krtap12-23
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391077,542,423 - 77,542,820 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1077,542,460 - 77,542,809 (+)EnsemblGRCm39 Ensembl
GRCm381077,706,589 - 77,706,986 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1077,706,626 - 77,706,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv371077,169,332 - 77,169,731 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1078,750,471 - 78,750,870 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
KRTAP12-3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382144,657,932 - 44,658,341 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2144,657,932 - 44,658,341 (+)EnsemblGRCh38hg38GRCh38
GRCh372146,077,849 - 46,078,258 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362144,902,277 - 44,902,686 (+)NCBINCBI36Build 36hg18NCBI36
Build 342144,902,276 - 44,902,686NCBI
Celera2131,185,485 - 31,185,894 (+)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2131,452,020 - 31,452,429 (+)NCBIHuRef
CHM1_12145,638,690 - 45,639,099 (+)NCBICHM1_1
T2T-CHM13v2.02143,018,378 - 43,018,787 (+)NCBIT2T-CHM13v2.0
LOC100991542
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22240,704,189 - 40,704,598 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12135,574,953 - 35,575,362 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02130,952,706 - 30,953,103 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12144,247,072 - 44,247,469 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2144,247,114 - 44,247,404 (+)Ensemblpanpan1.1panPan2
LOC610882
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13136,039,505 - 36,040,735 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3135,193,653 - 35,195,031 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03135,557,601 - 35,558,979 (-)NCBIROS_Cfam_1.0
UNSW_CanFamBas_1.03135,431,739 - 35,432,785 (-)NCBIUNSW_CanFamBas_1.0
KRTAP12-3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1288,373,725 - 88,374,783 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl288,374,230 - 88,374,517 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605416,505,735 - 16,506,416 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Krtap12-23
8 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:172
Count of miRNA genes:162
Interacting mature miRNAs:171
Transcripts:ENSMUST00000092371
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
4142313Angvq1_mangiogenesis by VEGF QTL 1 (mouse)Not determined4672040382491121Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104933801283338157Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined104984818783848412Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined104984818783848412Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined104984818783848412Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined104984822283848397Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined104984822283848397Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105109149085091639Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105109149085091639Mouse
1301380Cia8_mcollagen induced arthritis QTL 8 (mouse)Not determined105149340082491121Mouse
14746991Manh68_mmandible shape 68 (mouse)105228049786280497Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105851696992517096Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1063935779115935905Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106549093899491121Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106549093899491121Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106549093899491121Mouse
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106684818792258673Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067335830111735905Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073506901107507047Mouse
4142107Obrq12_mobesity resistance QTL 12 (mouse)Not determined7398721682491121Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075338568109338767Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75338568109338767Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075338568109338767Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000092371   ⟹   ENSMUSP00000090025
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1077,542,460 - 77,542,809 (+)Ensembl
GRCm38.p6 Ensembl1077,706,626 - 77,706,975 (+)Ensembl
RefSeq Acc Id: NM_001384208   ⟹   NP_001371137
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391077,542,423 - 77,542,820 (+)NCBI
GRCm381077,706,589 - 77,706,986 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001371137 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000090025
  ENSMUSP00000090025.4
Reference Protein Sequences
RefSeq Acc Id: NP_001371137   ⟸   NM_001384208
- UniProtKB: F7CZ33 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000090025   ⟸   ENSMUST00000092371

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F7CZ33-F1-model_v2 AlphaFold F7CZ33 1-110 view protein structure

Promoters
RGD ID:8672432
Promoter ID:EPDNEW_M14247
Type:single initiation site
Name:Gm10272_1
Description:Mus musculus predicted gene 10272 , non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381077,706,591 - 77,706,651EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3642183 AgrOrtholog
Ensembl Genes ENSMUSG00000069584 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000092371 ENTREZGENE
  ENSMUST00000092371.5 UniProtKB/TrEMBL
InterPro Keratin_B2 UniProtKB/TrEMBL
MGD MGI:3642183 ENTREZGENE
NCBI Gene 16697 ENTREZGENE
Pfam Keratin_B2_2 UniProtKB/TrEMBL
PhenoGen Krtap12-23 PhenoGen
UniProt F7CZ33 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-02-19 Krtap12-23  keratin associated protein 12-23  Gm10272  predicted gene 10272  Symbol and/or name updated 27372883 PROVISIONAL