NTF4 (neurotrophin 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: NTF4 (neurotrophin 4) Pan paniscus
Analyze
Symbol: NTF4
Name: neurotrophin 4
RGD ID: 329331838
Description: ENCODES a protein that exhibits growth factor activity (inferred); nerve growth factor receptor binding (inferred); INVOLVED IN adult locomotory behavior (ortholog); epidermis development (ortholog); ganglion mother cell fate determination (ortholog); ASSOCIATED WITH asthma (ortholog); autistic disorder (ortholog); developmental and epileptic encephalopathy 12 (ortholog); FOUND IN axon (inferred); dendrite (inferred); extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC129394720; neurotrophin-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,175,303 - 55,179,596 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,094,760 - 57,099,077 (-)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl1954,995,009 - 54,995,641 (-)Ensemblpanpan1.1panPan2


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NTF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,175,303 - 55,179,596 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,094,760 - 57,099,077 (-)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl1954,995,009 - 54,995,641 (-)Ensemblpanpan1.1panPan2
NTF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,058,284 - 49,065,035 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,061,066 - 49,065,076 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,564,385 - 49,568,292 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,256,209 - 54,260,047 (-)NCBINCBI36Build 36hg18NCBI36
Build 341954,256,210 - 54,258,937NCBI
Celera1946,431,605 - 46,435,443 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,941,069 - 45,943,797 (-)NCBIHuRef
CHM1_11949,566,638 - 49,569,366 (-)NCBICHM1_1
T2T-CHM13v2.01952,053,068 - 52,059,823 (-)NCBIT2T-CHM13v2.0
Ntf5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,063,119 - 45,066,603 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,063,119 - 45,066,603 (+)EnsemblGRCm39 Ensembl
GRCm38745,413,695 - 45,417,179 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,413,695 - 45,417,179 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,669,065 - 52,672,549 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,281,737 - 45,285,221 (+)NCBIMGSCv36mm8
Celera740,869,726 - 40,873,213 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.3NCBI
Ntf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,030,035 - 105,032,866 (+)NCBIGRCr8
mRatBN7.2195,893,560 - 95,896,391 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,893,457 - 95,897,243 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,278,986 - 101,281,817 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,751,663 - 109,754,494 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,042,063 - 103,044,894 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,405,314 - 101,408,145 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,405,314 - 101,408,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,484,724 - 102,487,555 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,885,577 - 95,888,408 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,963,687 - 95,966,519 (+)NCBI
Celera190,149,153 - 90,151,984 (+)NCBICelera
RH 3.4 Map1909.3RGD
Cytogenetic Map1q22NCBI
Ntf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,647,685 - 1,650,553 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,647,685 - 1,650,553 (+)NCBIChiLan1.0ChiLan1.0
NTF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,371,335 - 107,377,238 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,371,335 - 107,376,987 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01107,895,849 - 107,901,840 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,895,849 - 107,901,548 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,563,703 - 107,569,398 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,209,908 - 107,215,558 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,045,520 - 108,051,170 (+)NCBIUU_Cfam_GSD_1.0
Ntf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,398,887 - 21,401,144 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366643,017,108 - 3,017,955 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NTF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,271,246 - 54,274,092 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,271,244 - 54,288,846 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,039,657 - 50,057,398 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NTF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,254,693 - 42,284,899 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,279,190 - 42,279,822 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,170,689 - 22,171,841 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ntf4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,007,801 - 5,008,451 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,005,935 - 5,008,694 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_055103541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000024496   ⟹   ENSPPAP00000005402
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1954,995,009 - 54,995,641 (-)Ensembl
RefSeq Acc Id: XM_055103541   ⟹   XP_054959516
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,175,303 - 55,179,596 (-)NCBI
NHGRI_mPanPan11957,094,760 - 57,099,077 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054959516 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000005402.1
Reference Protein Sequences
RefSeq Acc Id: XP_054959516   ⟸   XM_055103541
- UniProtKB: A0A2R8ZKB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000005402   ⟸   ENSPPAT00000024496
Protein Domains
Nerve growth factor-related


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000022345 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000024496.1 UniProtKB/TrEMBL
Gene3D-CATH Cystine-knot cytokines UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  Nerve_growth_factor-like UniProtKB/TrEMBL
  Nerve_growth_factor-rel UniProtKB/TrEMBL
  Nerve_growth_factor_CS UniProtKB/TrEMBL
  Neurotrophin-4 UniProtKB/TrEMBL
NCBI Gene LOC129394720 ENTREZGENE
PANTHER NERVE GROWTH FACTOR NGF -RELATED UniProtKB/TrEMBL
  NEUROTROPHIN-4 UniProtKB/TrEMBL
Pfam NGF UniProtKB/TrEMBL
PIRSF NGF UniProtKB/TrEMBL
PRINTS NEUROTROPHN4 UniProtKB/TrEMBL
  NGF UniProtKB/TrEMBL
PROSITE NGF_1 UniProtKB/TrEMBL
  NGF_2 UniProtKB/TrEMBL
SMART NGF UniProtKB/TrEMBL
Superfamily-SCOP Cystine-knot cytokines UniProtKB/TrEMBL
UniProt A0A2R8ZKB9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-21 NTF4  neurotrophin 4  LOC129394720  neurotrophin-4  Symbol and/or name change 5135510 APPROVED