Nme9 (NME/NM23 family member 9) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Nme9 (NME/NM23 family member 9) Mus musculus
Analyze
Symbol: Nme9
Name: NME/NM23 family member 9
RGD ID: 2313605
MGI Page MGI
Description: Predicted to enable nucleoside diphosphate kinase activity. Predicted to be involved in CTP biosynthetic process; GTP biosynthetic process; and UTP biosynthetic process. Predicted to be located in cell projection; cytoplasm; and cytoskeleton. Orthologous to human NME9 (NME/NM23 family member 9).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: thioredoxin domain containing 6; thioredoxin domain-containing protein 6; thioredoxin-like protein 2; Txl-2; Txndc; Txndc6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39999,338,296 - 99,361,952 (+)NCBIGRCm39GRCm39mm39
GRCm38999,456,243 - 99,479,899 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl999,451,475 - 99,474,751 (+)EnsemblGRCm38mm10GRCm38
MGSCv37999,356,662 - 99,380,318 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36999,261,243 - 99,280,883 (+)NCBIMGSCv36mm8
Celera998,991,693 - 99,014,756 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12569107  


Genomics

Comparative Map Data
Nme9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39999,338,296 - 99,361,952 (+)NCBIGRCm39GRCm39mm39
GRCm38999,456,243 - 99,479,899 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl999,451,475 - 99,474,751 (+)EnsemblGRCm38mm10GRCm38
MGSCv37999,356,662 - 99,380,318 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36999,261,243 - 99,280,883 (+)NCBIMGSCv36mm8
Celera998,991,693 - 99,014,756 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.72NCBI
NME9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383138,261,436 - 138,329,851 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3138,261,437 - 138,329,886 (-)EnsemblGRCh38hg38GRCh38
GRCh373137,980,278 - 138,048,693 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363139,462,969 - 139,531,418 (-)NCBINCBI36Build 36hg18NCBI36
Build 343139,462,976 - 139,531,426NCBI
Celera3136,405,167 - 136,473,614 (-)NCBICelera
Cytogenetic Map3q22.3NCBI
HuRef3135,355,341 - 135,423,786 (-)NCBIHuRef
CHM1_13137,944,061 - 138,012,504 (-)NCBICHM1_1
T2T-CHM13v2.03141,002,003 - 141,070,404 (-)NCBIT2T-CHM13v2.0
Nme9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,892,561 - 108,913,628 (+)NCBIGRCr8
mRatBN7.28100,013,190 - 100,034,511 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.08107,698,612 - 107,720,758 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08107,124,393 - 107,145,676 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48104,318,431 - 104,335,452 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera899,414,228 - 99,435,674 (+)NCBICelera
Cytogenetic Map8q31NCBI
Nme9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955501684,013 - 703,001 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955501684,307 - 703,199 (+)NCBIChiLan1.0ChiLan1.0
NME9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22136,182,234 - 136,241,740 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13136,212,225 - 136,246,466 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03135,330,855 - 135,361,599 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13142,780,006 - 142,808,880 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3142,780,510 - 142,808,817 (-)Ensemblpanpan1.1panPan2
NME9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12334,515,003 - 34,537,386 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2334,483,520 - 34,537,312 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2334,508,101 - 34,530,001 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02335,055,641 - 35,077,713 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2335,023,624 - 35,077,648 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12334,737,404 - 34,759,286 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02334,802,725 - 34,824,789 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02335,053,890 - 35,075,928 (-)NCBIUU_Cfam_GSD_1.0
Nme9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560273,865,662 - 73,910,005 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936540606,868 - 649,789 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936540608,139 - 649,754 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NME9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1379,052,208 - 79,114,506 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11379,083,604 - 79,114,959 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21386,694,373 - 86,714,090 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NME9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11552,212,974 - 52,271,540 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1552,212,905 - 52,242,271 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604125,225,506 - 25,284,630 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nme9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473014,804,338 - 14,831,319 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473014,804,025 - 14,831,271 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nme9
934 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966089077100089175Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967006220101006220Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968779563102779705Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968779563102779705Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969121898103121973Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969428566103428698Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972859058106859205Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972859058106859205Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974250230108250378Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976024387101406120Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985779563108518385Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989859058118767089Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
1301484Bwq6_mbody weight (mouse)Not determined993591658124359700Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993591658124359700Mouse
14746992Manh67_mmandible shape 67 (mouse)993865836124359700Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994863354112701997Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996746658124359700Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NM_001165957   ⟹   NP_001159429
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39999,338,296 - 99,361,952 (+)NCBI
GRCm38999,456,243 - 99,479,899 (+)ENTREZGENE
MGSCv37999,356,662 - 99,380,318 (+)RGD
Celera998,991,693 - 99,014,756 (+)RGD
cM Map9 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001159429 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A0A1L1SUL6 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000150820.2
Reference Protein Sequences
RefSeq Acc Id: NP_001159429   ⟸   NM_001165957
- Sequence:
Protein Domains
Thioredoxin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A1L1SUL6-F1-model_v2 AlphaFold A0A1L1SUL6 1-329 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:4359686 AgrOrtholog
Ensembl Genes ENSMUSG00000046242 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000163199.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.141 UniProtKB/Swiss-Prot
  Glutaredoxin UniProtKB/Swiss-Prot
InterPro NDK-like_dom UniProtKB/Swiss-Prot
  NDK-like_dom_sf UniProtKB/Swiss-Prot
  Nucleoside_diP_kinase UniProtKB/Swiss-Prot
  Thioredoxin-like_sf UniProtKB/Swiss-Prot
  Thioredoxin_CS UniProtKB/Swiss-Prot
  Thioredoxin_domain UniProtKB/Swiss-Prot
MGD MGI:4359686 ENTREZGENE
NCBI Gene 623534 ENTREZGENE
PANTHER NME/NM23 FAMILY MEMBER 8 UniProtKB/Swiss-Prot
  THIOREDOXIN DOMAIN-CONTAINING PROTEIN 6 UniProtKB/Swiss-Prot
Pfam NDK UniProtKB/Swiss-Prot
  Thioredoxin UniProtKB/Swiss-Prot
PhenoGen Nme9 PhenoGen
PRINTS NUCDPKINASE UniProtKB/Swiss-Prot
PROSITE NDPK_LIKE UniProtKB/Swiss-Prot
  THIOREDOXIN_1 UniProtKB/Swiss-Prot
SMART NDK UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot
  SSF54919 UniProtKB/Swiss-Prot
UniProt A0A1L1SUL6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-16 Nme9  NME/NM23 family member 9  NME9    Symbol and/or name change 5135510 APPROVED
2012-06-05 NME9  NME/NM23 family member 9  Txndc6  thioredoxin domain containing 6  Symbol and/or name change 5135510 APPROVED