Gvin2 (GTPase, very large interferon inducible 2) - Rat Genome Database

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Gene: Gvin2 (GTPase, very large interferon inducible 2) Mus musculus
Analyze
Symbol: Gvin2
Name: GTPase, very large interferon inducible 2 (Ensembl:GTPase, very large interferon inducible, family member 2)
RGD ID: 2308080
MGI Page MGI
Description: Orthologous to human GVINP1 (GTPase, very large interferon inducible pseudogene 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 100042856; Gm4070; Gvin1; interferon-induced very large GTPase 1; very large inducible GTPase-1; very large-inducible GTPase-1; VLIG-1
RGD Orthologs
Human
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397105,544,325 - 105,603,174 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7105,544,346 - 105,603,174 (-)EnsemblGRCm39 Ensembl
GRCm387105,895,118 - 105,953,967 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7105,895,139 - 105,953,967 (-)EnsemblGRCm38mm10GRCm38
MGSCv377113,043,635 - 113,102,494 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367113,043,632 - 113,102,494 (-)NCBIMGSCv36mm8
Celera7106,168,566 - 106,548,449 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12874213   PMID:16141072   PMID:16141073   PMID:17203969   PMID:29459677   PMID:30550785   PMID:32325033  


Genomics

Comparative Map Data
Gvin2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397105,544,325 - 105,603,174 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7105,544,346 - 105,603,174 (-)EnsemblGRCm39 Ensembl
GRCm387105,895,118 - 105,953,967 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7105,895,139 - 105,953,967 (-)EnsemblGRCm38mm10GRCm38
MGSCv377113,043,635 - 113,102,494 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367113,043,632 - 113,102,494 (-)NCBIMGSCv36mm8
Celera7106,168,566 - 106,548,449 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map755.98NCBI
GVINP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,713,139 - 6,721,879 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,714,610 - 6,721,880 (-)EnsemblGRCh38hg38GRCh38
GRCh37116,734,370 - 6,743,110 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,690,941 - 6,724,226 (-)NCBINCBI36Build 36hg18NCBI36
Celera116,853,465 - 6,862,205 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef116,392,900 - 6,401,640 (-)NCBIHuRef
CHM1_1116,733,298 - 6,742,024 (-)NCBICHM1_1
T2T-CHM13v2.0116,771,589 - 6,780,317 (-)NCBIT2T-CHM13v2.0
Gvin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81169,689,178 - 169,718,522 (-)NCBIGRCr8
mRatBN7.21160,279,767 - 160,306,701 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1160,277,126 - 160,306,331 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01173,233,675 - 173,259,901 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1173,252,058 - 173,259,702 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01180,225,787 - 180,252,086 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41163,695,019 - 163,701,215 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1158,197,255 - 158,223,770 (-)NCBICelera
Cytogenetic Map1q33NCBI
LOC110255361
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.193,018,492 - 3,070,593 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

Variants

.
Variants in Gvin2
1675 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:772
Count of miRNA genes:362
Interacting mature miRNAs:403
Transcripts:ENSMUST00000106766, ENSMUST00000176467, ENSMUST00000176969, ENSMUST00000176994
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785049208124199223Mouse
1301997Cia7_mcollagen induced arthritis QTL 7 (mouse)Not determined785365595112533819Mouse
1301647Elpt_melevated leptin (mouse)Not determined786500186120500329Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787043932121044066Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787043932121044066Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787043932121044066Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787143137119485380Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787249208126499172Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787249208126499172Mouse
27095929Pglq8_mpelvic girdle length QTL 8, 10 week (mouse)787849208108099207Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791482996125483156Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791482996125483156Mouse
13464255Ifvrq2_minfluenza virus resistance QTL 2 (mouse)792500698106455693Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105250663139250811Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105350008139350008Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000106766   ⟹   ENSMUSP00000102377
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7105,544,346 - 105,603,147 (-)Ensembl
GRCm38.p6 Ensembl7105,895,139 - 105,953,940 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176467   ⟹   ENSMUSP00000135898
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7105,544,346 - 105,603,165 (-)Ensembl
GRCm38.p6 Ensembl7105,895,139 - 105,953,958 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176969
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7105,576,239 - 105,603,160 (-)Ensembl
GRCm38.p6 Ensembl7105,927,032 - 105,953,953 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176994   ⟹   ENSMUSP00000135667
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7105,552,726 - 105,603,174 (-)Ensembl
GRCm38.p6 Ensembl7105,903,519 - 105,953,967 (-)Ensembl
RefSeq Acc Id: NM_001243039   ⟹   NP_001229968
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397105,544,325 - 105,603,174 (-)NCBI
GRCm387105,895,118 - 105,953,967 (-)NCBI
Celera7106,168,566 - 106,548,449 (-)NCBI
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001243040   ⟹   NP_001229969
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397105,544,325 - 105,603,174 (-)NCBI
GRCm387105,895,118 - 105,953,967 (-)NCBI
Celera7106,168,566 - 106,548,449 (-)NCBI
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017321896   ⟹   XP_017177385
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397105,544,569 - 105,563,754 (-)NCBI
GRCm387105,895,362 - 105,914,547 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001229969   ⟸   NM_001243040
- UniProtKB: Q8BL18 (UniProtKB/Swiss-Prot),   Q3U3F2 (UniProtKB/Swiss-Prot),   Q8CBA9 (UniProtKB/Swiss-Prot),   Q80SU7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001229968   ⟸   NM_001243039
- UniProtKB: Q8BL18 (UniProtKB/Swiss-Prot),   Q3U3F2 (UniProtKB/Swiss-Prot),   Q8CBA9 (UniProtKB/Swiss-Prot),   Q80SU7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017177385   ⟸   XM_017321896
- Peptide Label: isoform X1
- UniProtKB: Q8BL18 (UniProtKB/Swiss-Prot),   Q3U3F2 (UniProtKB/Swiss-Prot),   Q8CBA9 (UniProtKB/Swiss-Prot),   Q80SU7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000102377   ⟸   ENSMUST00000106766
RefSeq Acc Id: ENSMUSP00000135667   ⟸   ENSMUST00000176994
RefSeq Acc Id: ENSMUSP00000135898   ⟸   ENSMUST00000176467
Protein Domains
VLIG-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80SU7-F1-model_v2 AlphaFold Q80SU7 1-2427 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3782245 AgrOrtholog
Ensembl Genes ENSMUSG00000078606 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000106766 ENTREZGENE
  ENSMUST00000106766.9 UniProtKB/Swiss-Prot
  ENSMUST00000176467 ENTREZGENE
  ENSMUST00000176467.8 UniProtKB/Swiss-Prot
  ENSMUST00000176994.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
InterPro Alpha/beta_knot_MTases UniProtKB/Swiss-Prot
  G_VLIG_dom UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report mmu:100042856 UniProtKB/Swiss-Prot
MGD MGI:3782245 ENTREZGENE
NCBI Gene 100042856 ENTREZGENE
PANTHER GTP-BINDING UniProtKB/Swiss-Prot
  INTERFERON-INDUCED VERY LARGE GTPASE 1 UniProtKB/Swiss-Prot
PhenoGen Gvin2 PhenoGen
PROSITE G_VLIG UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
  SSF75217 UniProtKB/Swiss-Prot
UniProt GVIN1_MOUSE UniProtKB/Swiss-Prot
  H3BL64_MOUSE UniProtKB/TrEMBL
  Q3U3F2 ENTREZGENE
  Q80SU7 ENTREZGENE
  Q8BL18 ENTREZGENE
  Q8CBA9 ENTREZGENE
UniProt Secondary Q3U3F2 UniProtKB/Swiss-Prot
  Q8BL18 UniProtKB/Swiss-Prot
  Q8CBA9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-20 Gvin2  GTPase, very large interferon inducible 2  Gm4070  predicted gene 4070  Symbol and/or name updated 27372883 PROVISIONAL