Ccl21f (C-C motif chemokine ligand 21F) - Rat Genome Database

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Gene: Ccl21f (C-C motif chemokine ligand 21F) Mus musculus
Analyze
No known orthologs.
Symbol: Ccl21f
Name: C-C motif chemokine ligand 21F
RGD ID: 2300369
MGI Page MGI
Description: Predicted to enable chemokine activity. Predicted to be involved in several processes, including positive regulation of cellular component biogenesis; positive regulation of intracellular signal transduction; and regulation of leukocyte migration. Orthologous to human CCL21 (C-C motif chemokine ligand 21).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 6Ckine; Beta-chemokine exodus-2; C-C motif chemokine 21-like; c-C motif chemokine 21a-like; C-C motif chemokine 21b; C-C motif chemokine 21c; Ccl21b; Ccl21c; ENSMUSG00000073878; Gm13304; Scya21; Scya21b; Scya21c; Small-inducible cytokine A21b; Small-inducible cytokine A21c; TCA4; Thymus-derived chemotactic agent 4
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39442,114,787 - 42,115,917 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl442,114,817 - 42,115,917 (+)EnsemblGRCm39 Ensembl
GRCm38442,114,787 - 42,115,917 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl442,114,817 - 42,115,917 (+)EnsemblGRCm38mm10GRCm38
MGSCv37441,985,499 - 41,986,640 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36441,985,505 - 41,986,640 (+)NCBIMGSCv36mm8
Cytogenetic Map4A5NCBI
cM Map422.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:188
Count of miRNA genes:164
Interacting mature miRNAs:177
Transcripts:ENSMUST00000098123
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1302010Wta1_mweight adult 1 (mouse)Not determined4868324042683429Mouse
1558992Ses8_msalmonella enteritidis susceptibility 8 (mouse)Not determined4868324042683429Mouse
1301473Triglq1_mtriglyceride QTL 1 (mouse)Not determined4868324042683429Mouse
1302125Lxw1_mlupus BXSB x NZW 1 (mouse)Not determined4868324042683429Mouse
4141302Ssrq5_mstress response QTL 5 (mouse)Not determined868324042683430Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763283678Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
25440481Moaq1_mmodifier of alien QTL 1 (mouse)41950000046000000Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1302184Aaom1_mautoimmune aoritis in MRL mice 1 (mouse)Not determined42432229946332776Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
4142290Ssrq9_mstress response QTL 9 (mouse)Not determined3439516046332776Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
10412178Habiir2_mhyperoxic acute lung injury imprinted region 2 (mouse)Not determined43945212663283678Mouse

Markers in Region
AW987545  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4A5UniSTS
cM Map413.34UniSTS
cM Map413.3UniSTS
cM Map413.3UniSTS
Whitehead/MRC_RH4664.9UniSTS
AI159701  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4A5UniSTS
cM Map413.3UniSTS
cM Map413.34UniSTS
cM Map413.3UniSTS
Whitehead/MRC_RH4664.83UniSTS
Whitehead/MRC_RH4663.97UniSTS
Ccl21a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4A5UniSTS
cM Map413.34UniSTS
cM Map413.3UniSTS
cM Map413.3UniSTS
cM Map413.3UniSTS
cM Map413.34UniSTS
cM Map413.3UniSTS
Ccl21a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4A5UniSTS
cM Map413.34UniSTS
cM Map413.3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001193666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL824709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000098123   ⟹   ENSMUSP00000095727
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl442,114,817 - 42,115,917 (+)Ensembl
GRCm38.p6 Ensembl442,114,817 - 42,115,917 (+)Ensembl
RefSeq Acc Id: NM_001193666   ⟹   NP_001180595
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39442,114,787 - 42,115,917 (+)NCBI
GRCm38442,114,787 - 42,115,917 (+)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001180595 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000095727
  ENSMUSP00000095727.4
  ENSMUSP00000095732.4
  ENSMUSP00000136903.2
  ENSMUSP00000137149.2
GenBank Protein P86792 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001180595   ⟸   NM_001193666
- Peptide Label: precursor
- UniProtKB: Q5M8M5 (UniProtKB/Swiss-Prot),   P84443 (UniProtKB/Swiss-Prot),   P86793 (UniProtKB/Swiss-Prot),   P86792 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000095727   ⟸   ENSMUST00000098123

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P86792-F1-model_v2 AlphaFold P86792 1-133 view protein structure
AF-P86793-F1-model_v2 AlphaFold P86793 1-133 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3710514 AgrOrtholog
Ensembl Genes ENSMUSG00000073878 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSG00000094065 UniProtKB/Swiss-Prot
  ENSMUSG00000095675 UniProtKB/Swiss-Prot
  ENSMUSG00000096596 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000098123 ENTREZGENE
  ENSMUST00000098123.4 UniProtKB/Swiss-Prot
  ENSMUST00000098128.4 UniProtKB/Swiss-Prot
  ENSMUST00000178168.3 UniProtKB/Swiss-Prot
  ENSMUST00000178864.3 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.50.40 UniProtKB/Swiss-Prot
InterPro Chemokine_b/g/d UniProtKB/Swiss-Prot
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot
  Interleukin_8-like_sf UniProtKB/Swiss-Prot
KEGG Report mmu:100042493 UniProtKB/Swiss-Prot
  mmu:100504239 UniProtKB/Swiss-Prot
  mmu:100504346 UniProtKB/Swiss-Prot
  mmu:100862177 UniProtKB/Swiss-Prot
MGD MGI:3710514 ENTREZGENE
NCBI Gene 100504346 ENTREZGENE
PANTHER C-C MOTIF CHEMOKINE 21 UniProtKB/Swiss-Prot
  SMALL INDUCIBLE CYTOKINE A UniProtKB/Swiss-Prot
Pfam IL8 UniProtKB/Swiss-Prot
PhenoGen Ccl21f PhenoGen
SMART SCY UniProtKB/Swiss-Prot
Superfamily-SCOP Interleukin 8-like chemokines UniProtKB/Swiss-Prot
UniProt CC21B_MOUSE UniProtKB/Swiss-Prot
  CC21C_MOUSE UniProtKB/Swiss-Prot
  P84443 ENTREZGENE
  P86792 ENTREZGENE
  P86793 ENTREZGENE
  Q5M8M5 ENTREZGENE
UniProt Secondary O09002 UniProtKB/Swiss-Prot
  O09006 UniProtKB/Swiss-Prot
  P84443 UniProtKB/Swiss-Prot
  Q5M8M5 UniProtKB/Swiss-Prot
  Q91V84 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-25 Ccl21f  C-C motif chemokine ligand 21F  Gm13304  predicted gene 13304  Symbol and/or name updated 27372883 PROVISIONAL