Gene: Agxt (alanine-glyoxylate aminotransferase) Rattus norvegicus
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Symbol: Agxt
Name: alanine-glyoxylate aminotransferase
Description: ENCODES a protein that exhibits alanine-glyoxylate transaminase activity; amino acid binding; serine-pyruvate transaminase activity; INVOLVED IN glycine biosynthetic process, by transamination of glyoxylate; pyruvate biosynthetic process; response to cAMP; PARTICIPATES IN alanine metabolic pathway; dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; ASSOCIATED WITH Hyperoxaluria (ortholog); Hyperoxaluria, Primary (ortholog); Primary Hyperoxaluria Type 1 (ortholog); FOUND IN mitochondrial matrix; mitochondrion; peroxisome; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; 3H-1,2-dithiole-3-thione
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGT; alanine--glyoxylate aminotransferase; alanine-glyoxylate aminotransferase (serine-pyruvate aminotransferase); angiotensin receptor 2; serine--pyruvate aminotransferase; serine--pyruvate aminotransferase, mitochondrial; serine--pyruvate aminotransferase, peroxisomal; serine-pyruvate aminotransferase; serine:pyruvate aminotransferase SPT; serine:pyruvate aminotransferase, SPT,; serine:pyruvate/alanine:glyoxylate aminotransferase; Spat; SPT
Orthologs:
Homo sapiens (human) : AGXT (alanine-glyoxylate aminotransferase)  HGNC  AGR
Mus musculus (house mouse) : Agxt (alanine-glyoxylate aminotransferase)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Agxt (alanine-glyoxylate aminotransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : AGXT (alanine-glyoxylate aminotransferase)
Canis lupus familiaris (dog) : LOC100855679 (serine--pyruvate aminotransferase, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Agxt (alanine-glyoxylate aminotransferase)
more info ...
Allele / Splice: Agxt_v1   Agxt_v2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.09100,281,339 - 100,291,292 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0999,939,444 - 99,949,397 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4992,412,128 - 92,422,075 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1992,616,896 - 92,626,844 (+)NCBI
Celera991,210,785 - 91,220,737 (+)NCBICelera
Cytogenetic Map9q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Agxt
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2073
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE