Gene: Agxt (alanine-glyoxylate aminotransferase) Rattus norvegicus
Symbol: Agxt
Name: alanine-glyoxylate aminotransferase
Description: ENCODES a protein that exhibits alanine-glyoxylate transaminase activity; amino acid binding; serine-pyruvate transaminase activity; INVOLVED IN glycine biosynthetic process, by transamination of glyoxylate; pyruvate biosynthetic process; response to cAMP; PARTICIPATES IN alanine metabolic pathway; dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; ASSOCIATED WITH Hyperoxaluria (ortholog); Hyperoxaluria, Primary (ortholog); Primary Hyperoxaluria Type 1 (ortholog); FOUND IN mitochondrial matrix; mitochondrion; peroxisome; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; 3H-1,2-dithiole-3-thione
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGT; alanine--glyoxylate aminotransferase; alanine-glyoxylate aminotransferase (serine-pyruvate aminotransferase); angiotensin receptor 2; serine--pyruvate aminotransferase; serine--pyruvate aminotransferase, mitochondrial; serine--pyruvate aminotransferase, peroxisomal; serine-pyruvate aminotransferase; serine:pyruvate aminotransferase SPT; serine:pyruvate aminotransferase, SPT,; serine:pyruvate/alanine:glyoxylate aminotransferase; Spat; SPT
Homo sapiens (human) : AGXT (alanine-glyoxylate aminotransferase)  HGNC  AGR
Mus musculus (house mouse) : Agxt (alanine-glyoxylate aminotransferase)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Agxt (alanine-glyoxylate aminotransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : AGXT (alanine-glyoxylate aminotransferase)
Canis lupus familiaris (dog) : LOC100855679 (serine--pyruvate aminotransferase, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Agxt (alanine-glyoxylate aminotransferase)
more info ...
Allele / Splice: Agxt_v1   Agxt_v2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.09100,281,339 - 100,291,292 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0999,939,444 - 99,949,397 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4992,412,128 - 92,422,075 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1992,616,896 - 92,626,844 (+)NCBI
Celera991,210,785 - 91,220,737 (+)NCBICelera
Cytogenetic Map9q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Agxt
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2073
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE