Lyrm4 (LYR motif containing 4) - Rat Genome Database

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Gene: Lyrm4 (LYR motif containing 4) Heterocephalus glaber
Analyze
Symbol: Lyrm4
Name: LYR motif containing 4
RGD ID: 18935571
Description: ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN [2Fe-2S] cluster assembly (ortholog); [4Fe-4S] cluster assembly (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH combined oxidative phosphorylation deficiency 14 (ortholog); combined oxidative phosphorylation deficiency 19 (ortholog); hereditary spastic paraplegia 77 (ortholog); FOUND IN mitochondrial ISCU complex (ortholog); nuclear body (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LYR motif-containing protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475620,017,066 - 20,152,201 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475620,016,773 - 20,152,201 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Lyrm4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475620,017,066 - 20,152,201 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475620,016,773 - 20,152,201 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LYRM4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3865,031,753 - 5,260,950 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl65,103,629 - 5,260,950 (-)EnsemblGRCh38hg38GRCh38
GRCh3765,068,561 - 5,261,183 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3665,053,652 - 5,206,167 (-)NCBINCBI36Build 36hg18NCBI36
Build 3465,053,652 - 5,206,167NCBI
Celera66,335,563 - 6,487,960 (-)NCBICelera
Cytogenetic Map6p25.1NCBI
HuRef64,983,042 - 5,135,587 (-)NCBIHuRef
CHM1_165,110,792 - 5,263,814 (-)NCBICHM1_1
T2T-CHM13v2.064,900,453 - 5,130,157 (-)NCBIT2T-CHM13v2.0
Lyrm4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391336,162,778 - 36,301,543 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1336,162,378 - 36,301,509 (-)EnsemblGRCm39 Ensembl
GRCm381335,978,797 - 36,117,357 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1335,978,395 - 36,117,526 (-)EnsemblGRCm38mm10GRCm38
MGSCv371336,070,666 - 36,209,226 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361335,986,262 - 36,124,795 (-)NCBIMGSCv36mm8
Celera1337,094,464 - 37,232,801 (-)NCBICelera
Cytogenetic Map13A3.3NCBI
cM Map1314.44NCBI
Lyrm4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81728,951,912 - 29,067,300 (+)NCBIGRCr8
mRatBN7.21728,746,457 - 28,861,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1728,746,469 - 28,861,750 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1728,606,677 - 28,722,099 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01730,210,222 - 30,325,648 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01728,582,619 - 28,697,699 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01729,439,042 - 29,552,773 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1729,438,980 - 29,552,790 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01731,335,552 - 31,449,519 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1728,351,102 - 28,464,094 (+)NCBICelera
Cytogenetic Map17p12NCBI
Lyrm4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554658,346,012 - 8,470,251 (+)NCBIChiLan1.0ChiLan1.0
LYRM4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2519,660,550 - 19,890,104 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1615,684,672 - 15,894,094 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v064,887,010 - 5,096,384 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.165,126,916 - 5,279,037 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl65,127,918 - 5,279,038 (-)Ensemblpanpan1.1panPan2
LYRM4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1355,229,851 - 5,373,965 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha355,235,415 - 5,394,097 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0355,299,018 - 5,458,444 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1355,165,491 - 5,324,206 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0355,190,998 - 5,349,956 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0356,523,175 - 6,682,769 (-)NCBIUU_Cfam_GSD_1.0
Lyrm4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494618,936,119 - 19,081,120 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365347,205,614 - 7,350,525 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365347,205,538 - 7,350,114 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LYRM4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl73,070,470 - 3,192,922 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.173,034,846 - 3,193,123 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.273,095,387 - 3,261,184 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LYRM4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11766,921,386 - 67,077,331 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1766,921,596 - 67,076,843 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660445,050,918 - 5,208,300 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000006205   ⟹   ENSHGLP00000006130
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475620,017,066 - 20,152,201 (+)Ensembl
RefSeq Acc Id: XM_004847750   ⟹   XP_004847807
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475620,016,773 - 20,061,731 (+)NCBI
RefSeq Acc Id: XM_004847751   ⟹   XP_004847808
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475620,016,789 - 20,152,201 (+)NCBI
RefSeq Acc Id: XM_013073268   ⟹   XP_012928722
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475620,016,774 - 20,152,201 (+)NCBI
RefSeq Acc Id: XR_002396039
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475620,016,773 - 20,152,201 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004847807 (Get FASTA)   NCBI Sequence Viewer  
  XP_004847808 (Get FASTA)   NCBI Sequence Viewer  
  XP_012928722 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006130
GenBank Protein JAO01139 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004847807   ⟸   XM_004847750
- Peptide Label: isoform X2
RefSeq Acc Id: XP_012928722   ⟸   XM_013073268
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004847808   ⟸   XM_004847751
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JWU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000006130   ⟸   ENSHGLT00000006205


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004479 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000006205 ENTREZGENE
InterPro Complex1_LYR UniProtKB/TrEMBL
  Complex1_LYR_LYRM4 UniProtKB/TrEMBL
NCBI Gene Lyrm4 ENTREZGENE
PANTHER LYR MOTIF-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  PROTEIN C6ORF149 UniProtKB/TrEMBL
Pfam Complex1_LYR UniProtKB/TrEMBL
UniProt A0A0P6JWU7 ENTREZGENE, UniProtKB/TrEMBL