Itprip (inositol 1,4,5-trisphosphate receptor interacting protein) - Rat Genome Database

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Gene: Itprip (inositol 1,4,5-trisphosphate receptor interacting protein) Heterocephalus glaber
Analyze
Symbol: Itprip
Name: inositol 1,4,5-trisphosphate receptor interacting protein
RGD ID: 18927759
Description: ENCODES a protein that exhibits protein kinase inhibitor activity (inferred); INVOLVED IN extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (ortholog); ASSOCIATED WITH desmoplastic/nodular medulloblastoma (ortholog); FOUND IN membrane (inferred); nuclear outer membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inositol 1,4,5-trisphosphate receptor-interacting protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248313,383,623 - 3,385,275 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248313,381,920 - 3,403,903 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Itprip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248313,383,623 - 3,385,275 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248313,381,920 - 3,403,903 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ITPRIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810104,309,700 - 104,338,465 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10104,309,698 - 104,338,465 (-)EnsemblGRCh38hg38GRCh38
GRCh3710106,069,458 - 106,098,223 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610106,061,889 - 106,083,653 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410106,061,890 - 106,083,653NCBI
Celera1099,812,709 - 99,834,473 (-)NCBICelera
Cytogenetic Map10q25.1NCBI
HuRef1099,701,183 - 99,729,977 (-)NCBIHuRef
CHM1_110106,353,303 - 106,382,108 (-)NCBICHM1_1
T2T-CHM13v2.010105,197,853 - 105,226,599 (-)NCBIT2T-CHM13v2.0
Itprip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391947,883,029 - 47,907,738 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1947,883,041 - 47,907,738 (-)EnsemblGRCm39 Ensembl
GRCm381947,894,590 - 47,919,323 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1947,894,602 - 47,919,299 (-)EnsemblGRCm38mm10GRCm38
MGSCv371947,969,086 - 47,993,789 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361947,947,911 - 47,972,592 (-)NCBIMGSCv36mm8
Celera1948,655,105 - 48,680,223 (-)NCBICelera
Cytogenetic Map19D1NCBI
cM Map1940.49NCBI
Itprip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81256,704,087 - 256,727,661 (-)NCBIGRCr8
mRatBN7.21246,762,804 - 246,786,379 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1246,762,472 - 246,786,408 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1254,890,123 - 254,913,689 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01261,583,120 - 261,606,701 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01254,232,976 - 254,256,534 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01267,649,385 - 267,673,341 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.01271,252,447 - 271,272,169 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1267,651,320 - 267,653,389 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1271,252,447 - 271,275,989 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01275,081,233 - 275,105,151 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1242,526,571 - 242,546,524 (-)NCBICelera
Cytogenetic Map1q54NCBI
Itprip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554856,336,790 - 6,359,049 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554856,335,670 - 6,360,757 (+)NCBIChiLan1.0ChiLan1.0
ITPRIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28116,198,401 - 116,215,237 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110116,203,730 - 116,232,717 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010100,911,715 - 100,938,543 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110104,368,059 - 104,397,193 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10104,372,767 - 104,374,410 (-)Ensemblpanpan1.1panPan2
ITPRIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12816,613,934 - 16,638,058 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2816,777,662 - 16,810,220 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02817,083,435 - 17,115,964 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12816,630,989 - 16,663,461 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02816,659,631 - 16,692,168 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02816,798,322 - 16,830,859 (-)NCBIUU_Cfam_GSD_1.0
Itprip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721330,271,144 - 30,294,808 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366001,895,714 - 1,897,384 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366001,874,696 - 1,898,033 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITPRIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14115,252,791 - 115,277,654 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114115,243,035 - 115,278,137 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214125,221,987 - 125,246,701 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITPRIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1997,362,766 - 97,384,115 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604858,483,619 - 58,507,504 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000028835   ⟹   ENSHGLP00000028376
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248313,383,623 - 3,385,275 (-)Ensembl
RefSeq Acc Id: XM_004866507   ⟹   XP_004866564
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248313,381,920 - 3,403,901 (-)NCBI
RefSeq Acc Id: XM_004866508   ⟹   XP_004866565
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248313,381,920 - 3,403,903 (-)NCBI
RefSeq Acc Id: XM_004866509   ⟹   XP_004866566
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248313,381,920 - 3,402,945 (-)NCBI
RefSeq Acc Id: XM_004866510   ⟹   XP_004866567
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248313,381,920 - 3,402,946 (-)NCBI
RefSeq Acc Id: XM_021245553   ⟹   XP_021101212
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248313,381,920 - 3,391,457 (-)NCBI
RefSeq Acc Id: XM_021245554   ⟹   XP_021101213
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248313,381,920 - 3,393,442 (-)NCBI
RefSeq Acc Id: XM_021245555   ⟹   XP_021101214
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248313,381,920 - 3,391,457 (-)NCBI
RefSeq Acc Id: XM_021245556   ⟹   XP_021101215
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248313,381,920 - 3,393,442 (-)NCBI
RefSeq Acc Id: XM_021245557   ⟹   XP_021101216
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248313,381,920 - 3,390,629 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004866565   ⟸   XM_004866508
- UniProtKB: G5C8J4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004866564   ⟸   XM_004866507
- UniProtKB: G5C8J4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004866567   ⟸   XM_004866510
- UniProtKB: G5C8J4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004866566   ⟸   XM_004866509
- UniProtKB: G5C8J4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101215   ⟸   XM_021245556
- UniProtKB: G5C8J4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101213   ⟸   XM_021245554
- UniProtKB: G5C8J4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101214   ⟸   XM_021245555
- UniProtKB: G5C8J4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101212   ⟸   XM_021245553
- UniProtKB: G5C8J4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101216   ⟸   XM_021245557
- UniProtKB: G5C8J4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000028376   ⟸   ENSHGLT00000028835


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000020625 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000028835 ENTREZGENE
Gene3D-CATH 1.10.1410.40 UniProtKB/TrEMBL
InterPro ITPRIP-like UniProtKB/TrEMBL
  Mab-21-like UniProtKB/TrEMBL
NCBI Gene Itprip ENTREZGENE
PANTHER CELL FATE DETERMINING PROTEIN MAB21-RELATED UniProtKB/TrEMBL
  INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN UniProtKB/TrEMBL
PRINTS INOS145TPRIP UniProtKB/TrEMBL
SMART Mab-21 UniProtKB/TrEMBL
UniProt G5C8J4 ENTREZGENE, UniProtKB/TrEMBL