Uchl1 (ubiquitin C-terminal hydrolase L1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Uchl1 (ubiquitin C-terminal hydrolase L1) Heterocephalus glaber
Analyze
Symbol: Uchl1
Name: ubiquitin C-terminal hydrolase L1
RGD ID: 18919326
Description: ENCODES a protein that exhibits alpha-2A adrenergic receptor binding (ortholog); cysteine-type endopeptidase activity (ortholog); omega peptidase activity (ortholog); INVOLVED IN adult walking behavior (ortholog); axon target recognition (ortholog); axonal transport of mitochondrion (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Deglutition Disorders (ortholog); Diaphragmatic Hernia (ortholog); FOUND IN axon (ortholog); cytosol (ortholog); neuron projection terminus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ubiquitin carboxyl-terminal hydrolase isozyme L1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476125,784,257 - 25,797,549 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476125,786,028 - 25,797,641 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Uchl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476125,784,257 - 25,797,549 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476125,786,028 - 25,797,641 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
UCHL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38441,256,928 - 41,268,455 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl441,256,413 - 41,268,455 (+)EnsemblGRCh38hg38GRCh38
GRCh37441,258,945 - 41,270,472 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36440,953,686 - 40,965,203 (+)NCBINCBI36Build 36hg18NCBI36
Build 34441,099,856 - 41,111,373NCBI
Celera441,702,199 - 41,713,746 (+)NCBICelera
Cytogenetic Map4p13NCBI
HuRef440,580,844 - 40,592,391 (+)NCBIHuRef
CHM1_1441,259,044 - 41,270,591 (+)NCBICHM1_1
T2T-CHM13v2.0441,230,716 - 41,242,242 (+)NCBIT2T-CHM13v2.0
Uchl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39566,833,464 - 66,844,577 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl566,833,434 - 66,844,577 (+)EnsemblGRCm39 Ensembl
GRCm38566,676,121 - 66,687,234 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl566,676,091 - 66,687,234 (+)EnsemblGRCm38mm10GRCm38
MGSCv37567,067,360 - 67,078,473 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36566,955,425 - 66,966,369 (+)NCBIMGSCv36mm8
Celera563,976,841 - 63,987,914 (+)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map535.95NCBI
Uchl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81441,838,859 - 41,849,743 (-)NCBIGRCr8
mRatBN7.21441,485,031 - 41,495,590 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1441,485,031 - 41,495,590 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1441,831,048 - 41,841,616 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01443,131,128 - 43,141,696 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01441,611,942 - 41,622,510 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01443,133,224 - 43,143,942 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1443,133,218 - 43,143,973 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01442,928,247 - 42,938,981 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41444,114,392 - 44,124,947 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11444,116,782 - 44,127,338 (-)NCBI
Celera1440,639,549 - 40,650,302 (-)NCBICelera
Cytogenetic Map14p11NCBI
Uchl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554436,367,460 - 6,380,462 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554436,367,519 - 6,379,638 (-)NCBIChiLan1.0ChiLan1.0
UCHL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2341,440,064 - 41,451,601 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1441,633,489 - 41,645,029 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0435,580,755 - 35,592,314 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1441,432,367 - 41,440,129 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl441,428,759 - 41,440,129 (+)Ensemblpanpan1.1panPan2
UCHL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1371,396,694 - 71,430,395 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl371,370,822 - 71,411,350 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha373,946,978 - 73,961,370 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0372,157,557 - 72,171,966 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1371,427,585 - 71,441,983 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0371,589,640 - 71,604,050 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0371,972,745 - 71,987,146 (-)NCBIUU_Cfam_GSD_1.0
Uchl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528537,734,649 - 37,746,530 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364828,551,603 - 8,563,651 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364828,551,749 - 8,563,586 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UCHL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl832,353,246 - 32,367,332 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1832,353,766 - 32,367,288 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2833,970,620 - 33,982,399 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UCHL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1279,074,961 - 9,086,606 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl279,074,923 - 9,086,517 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604755,406,774 - 55,418,174 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000014906   ⟹   ENSHGLP00000014761
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476125,784,257 - 25,797,549 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000014907   ⟹   ENSHGLP00000014762
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476125,786,347 - 25,797,488 (-)Ensembl
RefSeq Acc Id: XM_004849812   ⟹   XP_004849869
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476125,786,028 - 25,797,641 (-)NCBI
RefSeq Acc Id: XM_021262420   ⟹   XP_021118079
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476125,786,028 - 25,797,503 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004849869 (Get FASTA)   NCBI Sequence Viewer  
  XP_021118079 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA98557 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014761
  ENSHGLP00000014762
GenBank Protein JAN96763 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004849869   ⟸   XM_004849812
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J8V4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118079   ⟸   XM_021262420
- Peptide Label: isoform X2
- UniProtKB: G5ANE7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000014762   ⟸   ENSHGLT00000014907
RefSeq Acc Id: ENSHGLP00000014761   ⟸   ENSHGLT00000014906


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010549 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000014906 ENTREZGENE
  ENSHGLT00000014907 ENTREZGENE
Gene3D-CATH 3.40.532.10 UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C12_UCH UniProtKB/TrEMBL
  Peptidase_C12_UCH_sf UniProtKB/TrEMBL
KEGG Report hgl:101702892 UniProtKB/TrEMBL
NCBI Gene Uchl1 ENTREZGENE
PANTHER PTHR10589 UniProtKB/TrEMBL
  PTHR10589:SF19 UniProtKB/TrEMBL
Pfam Peptidase_C12 UniProtKB/TrEMBL
PRINTS UBCTHYDRLASE UniProtKB/TrEMBL
PROSITE UCH_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
UniProt A0A0P6J8V4 ENTREZGENE, UniProtKB/TrEMBL
  G5ANE7 ENTREZGENE, UniProtKB/TrEMBL