Klf14 (KLF transcription factor 14) - Rat Genome Database

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Gene: Klf14 (KLF transcription factor 14) Heterocephalus glaber
Analyze
Symbol: Klf14
Name: KLF transcription factor 14 (Ensembl:Kruppel like factor 14)
RGD ID: 18919298
Description: ENCODES a protein that exhibits chromatin binding (ortholog); sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN positive regulation of sphingolipid mediated signaling pathway (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Dyslipidemias (ortholog); genetic disease (ortholog); Insulin Resistance (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Krueppel-like factor 14; Kruppel like factor 14
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247835,593,860 - 5,594,855 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247835,593,860 - 5,595,803 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Klf14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247835,593,860 - 5,594,855 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247835,593,860 - 5,595,803 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KLF14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387130,730,697 - 130,734,207 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7130,730,697 - 130,734,207 (-)EnsemblGRCh38hg38GRCh38
GRCh377130,415,525 - 130,418,967 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367130,068,018 - 130,069,400 (-)NCBINCBI36Build 36hg18NCBI36
Build 347129,874,732 - 129,876,115NCBI
Celera7125,165,236 - 125,166,729 (-)NCBICelera
Cytogenetic Map7q32.2NCBI
HuRef7124,732,836 - 124,734,091 (-)NCBIHuRef
CHM1_17130,350,998 - 130,352,477 (-)NCBICHM1_1
T2T-CHM13v2.07132,044,973 - 132,048,483 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27129,753,857 - 129,755,336 (-)NCBI
Klf14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39630,932,956 - 30,935,925 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl630,932,958 - 30,936,013 (-)EnsemblGRCm39 Ensembl
GRCm38630,956,021 - 30,958,990 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl630,956,023 - 30,959,078 (-)EnsemblGRCm38mm10GRCm38
MGSCv37630,906,021 - 30,908,990 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36630,887,883 - 30,893,920 (-)NCBIMGSCv36mm8
MGSCv36631,109,536 - 31,115,573 (-)NCBIMGSCv36mm8
Celera630,940,993 - 30,943,962 (-)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.54NCBI
Klf14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8460,521,363 - 60,524,285 (-)NCBIGRCr8
mRatBN7.2459,554,011 - 59,556,933 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl459,554,011 - 59,556,933 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx464,525,020 - 64,527,942 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0460,441,206 - 60,444,128 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0458,843,148 - 58,846,070 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0458,247,876 - 58,250,798 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl458,247,876 - 58,250,798 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0458,003,838 - 58,006,760 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4458,010,538 - 58,013,460 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1458,234,580 - 58,434,364 (-)NCBI
Celera454,647,664 - 54,650,586 (-)NCBICelera
Cytogenetic Map4q22NCBI
Klf14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541036,891,213 - 36,932,136 (+)NCBIChiLan1.0ChiLan1.0
KLF14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26167,549,657 - 167,551,313 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1719,558,044 - 19,561,557 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07122,695,015 - 122,696,635 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17135,211,891 - 135,212,975 (-)NCBIpanpan1.1PanPan1.1panPan2
KLF14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1146,289,163 - 6,292,459 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl146,289,163 - 6,290,110 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha145,949,440 - 5,952,593 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0146,023,394 - 6,026,547 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl146,023,394 - 6,024,341 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1146,228,821 - 6,231,974 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0145,973,983 - 5,977,136 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0146,117,539 - 6,120,692 (+)NCBIUU_Cfam_GSD_1.0
Klf14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511824,454,475 - 24,455,914 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365794,587,081 - 4,588,010 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365794,587,072 - 4,588,505 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLF14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1818,147,124 - 18,149,177 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11818,147,124 - 18,149,177 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21819,167,742 - 19,169,796 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLF14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12199,361,461 - 99,363,067 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2199,361,955 - 99,362,926 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660424,025,569 - 4,027,384 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004856463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01059834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000028828   ⟹   ENSHGLP00000028370
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247835,593,860 - 5,594,855 (+)Ensembl
RefSeq Acc Id: XM_004856463   ⟹   XP_004856520
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247835,593,860 - 5,595,803 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004856520 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000028370
Reference Protein Sequences
RefSeq Acc Id: XP_004856520   ⟸   XM_004856463
RefSeq Acc Id: ENSHGLP00000028370   ⟸   ENSHGLT00000028828


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000020618 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000028828 ENTREZGENE
NCBI Gene Klf14 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-12 Klf14  KLF transcription factor 14  Klf14  Kruppel like factor 14  Symbol and/or name change 5135510 APPROVED