Nacad (NAC alpha domain containing) - Rat Genome Database

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Gene: Nacad (NAC alpha domain containing) Heterocephalus glaber
Analyze
Symbol: Nacad
Name: NAC alpha domain containing
RGD ID: 18918319
Description: ENCODES a protein that exhibits unfolded protein binding (inferred); INVOLVED IN protein targeting to membrane (inferred); ASSOCIATED WITH cerebral cavernous malformation 2 (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN cytoplasm (inferred); nascent polypeptide-associated complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NAC-alpha domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247407,299,294 - 7,307,056 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Nacad
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247407,299,294 - 7,307,056 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NACAD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38745,080,437 - 45,088,969 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl745,080,437 - 45,088,969 (-)EnsemblGRCh38hg38GRCh38
GRCh37745,120,036 - 45,128,568 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36745,067,578 - 45,095,757 (-)NCBINCBI36Build 36hg18NCBI36
Celera745,218,992 - 45,227,329 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef745,004,007 - 45,012,344 (-)NCBIHuRef
CHM1_1745,123,853 - 45,132,190 (-)NCBICHM1_1
T2T-CHM13v2.0745,241,246 - 45,249,778 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2745,159,326 - 45,167,663 (-)NCBI
Nacad
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39116,547,814 - 6,556,059 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl116,547,823 - 6,556,053 (-)EnsemblGRCm39 Ensembl
GRCm38116,597,814 - 6,606,059 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl116,597,823 - 6,606,053 (-)EnsemblGRCm38mm10GRCm38
MGSCv37116,497,826 - 6,506,057 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36116,497,823 - 6,506,057 (-)NCBIMGSCv36mm8
MGSCv36116,482,285 - 6,490,519 (-)NCBIMGSCv36mm8
Cytogenetic Map11A1NCBI
cM Map114.6NCBI
Nacad
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,679,215 - 85,688,742 (-)NCBIGRCr8
mRatBN7.21481,465,299 - 81,473,866 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,465,299 - 81,473,781 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,866,587 - 85,875,069 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01487,106,390 - 87,114,872 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01483,555,986 - 83,564,468 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,860,607 - 86,868,605 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,860,608 - 86,868,598 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01480,494,051 - 80,502,042 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,354,263 - 87,363,221 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1480,347,050 - 80,355,532 (-)NCBICelera
Cytogenetic Map14q21NCBI
Nacad
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,224,202 - 7,230,660 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554567,224,224 - 7,230,736 (+)NCBIChiLan1.0ChiLan1.0
NACAD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2649,993,705 - 50,003,426 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1798,318,443 - 98,328,164 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0745,794,340 - 45,802,532 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1745,861,001 - 45,869,388 (-)NCBIpanpan1.1PanPan1.1panPan2
NACAD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11610,393,993 - 10,394,424 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha162,610,385 - 2,618,972 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,241,933 - 14,250,521 (+)NCBIROS_Cfam_1.0
UNSW_CanFamBas_1.01613,875,029 - 13,883,618 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01613,854,540 - 13,863,130 (+)NCBIUU_Cfam_GSD_1.0
Nacad
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118100,672,261 - 100,682,284 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,884,067 - 19,893,673 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,883,992 - 19,893,917 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NACAD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11850,385,116 - 50,394,787 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,216,074 - 55,225,617 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NACAD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12113,594,969 - 13,603,436 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2113,598,304 - 13,605,614 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660628,925,669 - 8,934,341 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_021254264   ⟹   XP_021109923
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247407,299,720 - 7,307,056 (+)NCBI
RefSeq Acc Id: XM_021254265   ⟹   XP_021109924
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247407,299,719 - 7,307,056 (+)NCBI
RefSeq Acc Id: XM_021254266   ⟹   XP_021109925
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247407,299,294 - 7,307,056 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021109923 (Get FASTA)   NCBI Sequence Viewer  
  XP_021109924 (Get FASTA)   NCBI Sequence Viewer  
  XP_021109925 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021109925   ⟸   XM_021254266
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021109924   ⟸   XM_021254265
- Peptide Label: isoform X2
- UniProtKB: G5BIL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109923   ⟸   XM_021254264
- Peptide Label: isoform X1
- UniProtKB: G5BIL7 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  Nascent polypeptide-associated complex domain UniProtKB/TrEMBL
InterPro EGD2/NACA UniProtKB/TrEMBL
  NAC-like_UBA UniProtKB/TrEMBL
  NAC_A/B_dom_sf UniProtKB/TrEMBL
  Nas_poly-pep-assoc_cplx_dom UniProtKB/TrEMBL
NCBI Gene Nacad ENTREZGENE
PANTHER NAC-ALPHA DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED UniProtKB/TrEMBL
Pfam HYPK_UBA UniProtKB/TrEMBL
  NAC UniProtKB/TrEMBL
PROSITE NAC_AB UniProtKB/TrEMBL
SMART NAC UniProtKB/TrEMBL
UniProt G5BIL7 ENTREZGENE, UniProtKB/TrEMBL