Impa2 (inositol monophosphatase 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Impa2 (inositol monophosphatase 2) Heterocephalus glaber
Analyze
Symbol: Impa2
Name: inositol monophosphatase 2
RGD ID: 18913444
Description: ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN response to lithium ion (ortholog); ASSOCIATED WITH bipolar disorder (ortholog); chromosome 18p deletion syndrome (ortholog); dystonia (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477019,526,446 - 19,548,386 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477019,526,796 - 19,549,113 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Impa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477019,526,446 - 19,548,386 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477019,526,796 - 19,549,113 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
IMPA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381811,981,507 - 12,030,877 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1811,981,025 - 12,030,877 (+)EnsemblGRCh38hg38GRCh38
GRCh371811,981,506 - 12,030,876 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361811,971,455 - 12,020,876 (+)NCBINCBI36Build 36hg18NCBI36
Build 341811,971,454 - 12,020,876NCBI
Celera1811,863,626 - 11,913,083 (+)NCBICelera
Cytogenetic Map18p11.21NCBI
HuRef1811,936,022 - 11,985,517 (+)NCBIHuRef
CHM1_11811,981,069 - 12,030,550 (+)NCBICHM1_1
T2T-CHM13v2.01812,144,221 - 12,193,612 (+)NCBIT2T-CHM13v2.0
Impa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391867,422,246 - 67,454,375 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1867,422,256 - 67,455,542 (+)EnsemblGRCm39 Ensembl
GRCm381867,289,247 - 67,319,216 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1867,289,186 - 67,322,472 (+)EnsemblGRCm38mm10GRCm38
MGSCv371867,448,877 - 67,478,495 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361867,414,592 - 67,444,210 (+)NCBIMGSCv36mm8
Celera1868,557,223 - 68,589,548 (+)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1839.92NCBI
Impa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81863,104,113 - 63,135,232 (+)NCBIGRCr8
mRatBN7.21860,834,206 - 60,867,575 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1860,834,246 - 60,865,641 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1862,905,859 - 62,936,953 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01863,604,635 - 63,635,729 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01861,454,773 - 61,485,968 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01863,016,577 - 63,050,123 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1863,016,577 - 63,047,781 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01862,201,776 - 62,233,111 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41863,809,336 - 63,840,069 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11863,882,536 - 63,913,270 (+)NCBI
Celera1858,940,928 - 58,971,996 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Impa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554021,121,838 - 1,143,507 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554021,119,376 - 1,143,589 (-)NCBIChiLan1.0ChiLan1.0
IMPA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21726,011,624 - 26,062,252 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11811,704,221 - 11,754,841 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0182,293,788 - 2,344,422 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1184,557,280 - 4,608,985 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl184,557,280 - 4,608,991 (-)Ensemblpanpan1.1panPan2
IMPA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1777,604,620 - 77,648,416 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl777,597,888 - 77,648,218 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha777,004,188 - 77,049,429 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0777,661,002 - 77,706,180 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl777,655,833 - 77,706,173 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1777,357,733 - 77,402,884 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0777,404,338 - 77,449,508 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0777,691,372 - 77,736,712 (+)NCBIUU_Cfam_GSD_1.0
Impa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049441,041,717 - 1,083,030 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936626268,727 - 310,787 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936626268,788 - 310,781 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IMPA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl697,280,010 - 97,309,745 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1697,280,008 - 97,309,729 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2690,736,855 - 90,768,966 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IMPA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11869,389,414 - 69,436,128 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1869,389,606 - 69,436,191 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605044,380,657 - 44,431,073 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000022890   ⟹   ENSHGLP00000022676
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477019,526,446 - 19,548,380 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000022891   ⟹   ENSHGLP00000022677
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477019,526,753 - 19,548,386 (+)Ensembl
RefSeq Acc Id: XM_004853257   ⟹   XP_004853314
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477019,526,802 - 19,549,113 (+)NCBI
RefSeq Acc Id: XM_021265268   ⟹   XP_021120927
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477019,526,796 - 19,545,238 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004853314 (Get FASTA)   NCBI Sequence Viewer  
  XP_021120927 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000022677
Reference Protein Sequences
RefSeq Acc Id: XP_021120927   ⟸   XM_021265268
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004853314   ⟸   XM_004853257
- Peptide Label: isoform X2
- UniProtKB: G5C074 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000022676   ⟸   ENSHGLT00000022890
RefSeq Acc Id: ENSHGLP00000022677   ⟸   ENSHGLT00000022891


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016172 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000022891 ENTREZGENE
Gene3D-CATH 3.40.190.80 UniProtKB/TrEMBL
  Fructose-1,6-Bisphosphatase, subunit A, domain 1 UniProtKB/TrEMBL
InterPro IMPase UniProtKB/TrEMBL
  Inositol_monoP_metal-BS UniProtKB/TrEMBL
  Inositol_monoPase_Li-sen UniProtKB/TrEMBL
  Inositol_monophosphatase-like UniProtKB/TrEMBL
  Inositol_monophosphatase_CS UniProtKB/TrEMBL
NCBI Gene Impa2 ENTREZGENE
PANTHER INOSITOL MONOPHOSPHATASE UniProtKB/TrEMBL
  INOSITOL MONOPHOSPHATASE 2 UniProtKB/TrEMBL
Pfam Inositol_P UniProtKB/TrEMBL
PRINTS IMPHPHTASES UniProtKB/TrEMBL
  LIIMPHPHTASE UniProtKB/TrEMBL
PROSITE IMP_1 UniProtKB/TrEMBL
  IMP_2 UniProtKB/TrEMBL
Superfamily-SCOP Carbohydrate phosphatase UniProtKB/TrEMBL
UniProt G5C074 ENTREZGENE, UniProtKB/TrEMBL