Angptl8 (angiopoietin like 8) - Rat Genome Database

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Gene: Angptl8 (angiopoietin like 8) Heterocephalus glaber
Analyze
Symbol: Angptl8
Name: angiopoietin like 8
RGD ID: 18912899
Description: INVOLVED IN cell maturation (ortholog); cellular lipid metabolic process (ortholog); fat cell differentiation (ortholog); ASSOCIATED WITH alpha-mannosidosis (ortholog); Charcot-Marie-Tooth disease dominant intermediate B (ortholog); episodic ataxia type 2 (ortholog); FOUND IN extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: angiopoietin-like protein 8; hepatocellular carcinoma-associated protein TD26 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248283,092,739 - 3,099,120 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248283,092,673 - 3,094,919 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Angptl8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248283,092,739 - 3,099,120 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248283,092,673 - 3,094,919 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ANGPTL8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381911,239,619 - 11,241,943 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1911,237,502 - 11,241,943 (+)EnsemblGRCh38hg38GRCh38
GRCh371911,350,295 - 11,352,619 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361911,209,817 - 11,213,619 (+)NCBINCBI36Build 36hg18NCBI36
Celera1911,245,140 - 11,247,464 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef1910,926,369 - 10,928,693 (+)NCBIHuRef
CHM1_11911,351,357 - 11,353,681 (+)NCBICHM1_1
T2T-CHM13v2.01911,366,594 - 11,368,918 (+)NCBIT2T-CHM13v2.0
Angptl8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39921,746,806 - 21,748,643 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl921,746,806 - 21,748,643 (+)EnsemblGRCm39 Ensembl
GRCm38921,835,510 - 21,837,347 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl921,835,510 - 21,837,347 (+)EnsemblGRCm38mm10GRCm38
MGSCv37921,639,954 - 21,641,791 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36921,585,740 - 21,587,757 (+)NCBIMGSCv36mm8
Celera919,105,101 - 19,106,938 (+)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.9NCBI
Angptl8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8828,652,555 - 28,654,581 (+)NCBIGRCr8
mRatBN7.2820,376,462 - 20,378,488 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl820,376,462 - 20,378,490 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx824,411,953 - 24,413,979 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0822,707,496 - 22,709,522 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0820,606,057 - 20,608,083 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0822,855,495 - 22,858,565 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,856,539 - 22,858,565 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0822,910,979 - 22,913,005 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4820,948,070 - 20,950,087 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera821,767,738 - 21,769,764 (+)NCBICelera
Cytogenetic Map8q13NCBI
Angptl8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554952,205,485 - 2,207,376 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554952,205,424 - 2,207,611 (+)NCBIChiLan1.0ChiLan1.0
ANGPTL8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22016,142,133 - 16,156,840 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11915,140,826 - 15,155,531 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01910,787,457 - 10,790,090 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11911,498,069 - 11,500,400 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1911,498,069 - 11,500,400 (+)Ensemblpanpan1.1panPan2
ANGPTL8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,040,383 - 50,043,312 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,040,383 - 50,042,031 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2049,913,888 - 49,915,655 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02050,561,284 - 50,563,051 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2050,561,284 - 50,562,932 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12049,771,477 - 49,773,244 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02050,198,362 - 50,200,129 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02050,441,068 - 50,442,835 (-)NCBIUU_Cfam_GSD_1.0
Angptl8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118208,982,926 - 208,984,600 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366591,370,113 - 1,371,769 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366591,370,115 - 1,371,767 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANGPTL8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl269,952,581 - 69,954,220 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1269,951,556 - 69,954,223 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ANGPTL8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1610,169,733 - 10,172,433 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl610,170,052 - 10,173,005 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660749,713,854 - 9,716,184 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000019651   ⟹   ENSHGLP00000019458
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248283,092,739 - 3,099,120 (+)Ensembl
RefSeq Acc Id: XM_004865567   ⟹   XP_004865624
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248283,092,673 - 3,094,919 (+)NCBI
RefSeq Acc Id: XM_004865568   ⟹   XP_004865625
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248283,092,677 - 3,094,919 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004865624 (Get FASTA)   NCBI Sequence Viewer  
  XP_004865625 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000019458
GenBank Protein JAN96108 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004865624   ⟸   XM_004865567
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004865625   ⟸   XM_004865568
- Peptide Label: isoform X2
- UniProtKB: A0A0P6IZ38 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000019458   ⟸   ENSHGLT00000019651


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013933 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000019651 ENTREZGENE
InterPro ANGPTL8 UniProtKB/TrEMBL
NCBI Gene Angptl8 ENTREZGENE
PANTHER ANGIOPOIETIN-LIKE PROTEIN 8 UniProtKB/TrEMBL
  PTHR21463 UniProtKB/TrEMBL
UniProt A0A0P6IZ38 ENTREZGENE, UniProtKB/TrEMBL