Pacsin3 (protein kinase C and casein kinase substrate in neurons 3) - Rat Genome Database

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Gene: Pacsin3 (protein kinase C and casein kinase substrate in neurons 3) Heterocephalus glaber
Analyze
Symbol: Pacsin3
Name: protein kinase C and casein kinase substrate in neurons 3
RGD ID: 18909674
Description: ENCODES a protein that exhibits calcium channel inhibitor activity (ortholog); cytoskeletal protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN negative regulation of calcium ion transport (ortholog); negative regulation of endocytosis (ortholog); positive regulation of membrane protein ectodomain proteolysis (ortholog); ASSOCIATED WITH congenital disorder of glycosylation type IIc (ortholog); fetal akinesia deformation sequence syndrome 1 (ortholog); hypertrophic cardiomyopathy (ortholog); FOUND IN cytosol (ortholog); trans-Golgi network (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein kinase C and casein kinase substrate in neurons protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247671,505,633 - 1,512,610 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247671,505,617 - 1,512,606 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pacsin3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247671,505,633 - 1,512,610 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247671,505,617 - 1,512,606 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PACSIN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381147,177,522 - 47,186,434 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1147,177,522 - 47,186,443 (-)EnsemblGRCh38hg38GRCh38
GRCh371147,199,073 - 47,207,985 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361147,155,654 - 47,164,534 (-)NCBINCBI36Build 36hg18NCBI36
Build 341147,155,660 - 47,164,534NCBI
Celera1147,338,301 - 47,347,238 (-)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1146,898,049 - 46,906,986 (-)NCBIHuRef
CHM1_11147,197,807 - 47,206,741 (-)NCBICHM1_1
T2T-CHM13v2.01147,334,276 - 47,343,188 (-)NCBIT2T-CHM13v2.0
Pacsin3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39291,086,215 - 91,095,025 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl291,086,299 - 91,095,024 (+)EnsemblGRCm39 Ensembl
GRCm38291,255,875 - 91,264,680 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl291,255,954 - 91,264,679 (+)EnsemblGRCm38mm10GRCm38
MGSCv37291,096,970 - 91,104,836 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36291,053,440 - 91,065,517 (+)NCBIMGSCv36mm8
Celera292,642,292 - 92,650,140 (+)NCBICelera
Cytogenetic Map2E1NCBI
cM Map250.61NCBI
Pacsin3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8397,683,054 - 97,691,619 (+)NCBIGRCr8
mRatBN7.2377,227,187 - 77,235,820 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl377,222,710 - 77,235,811 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx380,705,464 - 80,714,024 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0389,304,479 - 89,313,039 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0387,155,613 - 87,164,184 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0380,072,425 - 80,081,058 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl380,072,489 - 80,081,047 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0386,780,541 - 86,789,813 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,611,040 - 75,619,605 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1375,511,254 - 75,515,587 (+)NCBI
Celera376,433,959 - 76,442,528 (+)NCBICelera
Cytogenetic Map3q24NCBI
Pacsin3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955422989,605 - 995,140 (+)NCBIChiLan1.0ChiLan1.0
PACSIN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2949,377,358 - 49,386,313 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11149,397,164 - 49,406,067 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01147,122,620 - 47,131,559 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11147,676,432 - 47,685,362 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1147,676,432 - 47,684,485 (-)Ensemblpanpan1.1panPan2
PACSIN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11842,378,692 - 42,399,225 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1842,389,951 - 42,398,924 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1841,107,149 - 41,127,919 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01843,032,479 - 43,053,469 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1843,044,881 - 43,053,469 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11842,519,000 - 42,539,778 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01842,073,947 - 42,094,718 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01842,803,847 - 42,824,628 (+)NCBIUU_Cfam_GSD_1.0
Pacsin3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494719,877,198 - 19,883,975 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365621,989,662 - 1,995,580 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365621,988,839 - 1,995,597 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PACSIN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl215,381,707 - 15,389,887 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1215,380,297 - 15,389,893 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2216,604,963 - 16,613,448 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PACSIN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,125,207 - 18,135,866 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,130,727 - 18,135,454 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038115,428,210 - 115,437,090 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


RefSeq Acc Id: ENSHGLT00000026455   ⟹   ENSHGLP00000026221
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247671,505,633 - 1,512,610 (+)Ensembl
RefSeq Acc Id: XM_004851887   ⟹   XP_004851944
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247671,505,617 - 1,512,606 (+)NCBI
RefSeq Acc Id: XM_004851888   ⟹   XP_004851945
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247671,505,632 - 1,512,606 (+)NCBI
RefSeq Acc Id: XM_004851889   ⟹   XP_004851946
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247671,505,629 - 1,512,606 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004851944 (Get FASTA)   NCBI Sequence Viewer  
  XP_004851945 (Get FASTA)   NCBI Sequence Viewer  
  XP_004851946 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000026221
RefSeq Acc Id: XP_004851944   ⟸   XM_004851887
- UniProtKB: G5BPC1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851946   ⟸   XM_004851889
- UniProtKB: G5BPC1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851945   ⟸   XM_004851888
- UniProtKB: G5BPC1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000026221   ⟸   ENSHGLT00000026455


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018661 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000026455 ENTREZGENE
Gene3D-CATH Arfaptin homology (AH) domain/BAR domain UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/TrEMBL
  F_BAR UniProtKB/TrEMBL
  FCH_dom UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene Pacsin3 ENTREZGENE
PANTHER PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 UniProtKB/TrEMBL
  PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 3 UniProtKB/TrEMBL
Pfam FCH UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PRINTS SH3DOMAIN UniProtKB/TrEMBL
PROSITE F_BAR UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART FCH UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP BAR/IMD domain-like UniProtKB/TrEMBL
  SH3-domain UniProtKB/TrEMBL
UniProt G5BPC1 ENTREZGENE, UniProtKB/TrEMBL