Plpp1 (phospholipid phosphatase 1) - Rat Genome Database

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Gene: Plpp1 (phospholipid phosphatase 1) Heterocephalus glaber
Analyze
Symbol: Plpp1 (Ensembl: PPAP2A)
Name: phospholipid phosphatase 1
RGD ID: 18904193
Description: ENCODES a protein that exhibits ceramide-1-phosphate phosphatase activity (ortholog); diacylglycerol diphosphate phosphatase activity (ortholog); lipid phosphatase activity (ortholog); INVOLVED IN ceramide metabolic process (ortholog); phospholipid catabolic process (ortholog); sphingosine metabolic process (ortholog); PARTICIPATES IN D-glycericacidemia pathway; Fabry disease pathway; familial lipoprotein lipase deficiency pathway; ASSOCIATED WITH Disease Progression (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN membrane (ortholog); membrane raft (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Lipid phosphate phosphohydrolase 1; PPAP2A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247593,780,826 - 3,868,869 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247593,780,904 - 3,868,867 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Plpp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247593,780,826 - 3,868,869 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247593,780,904 - 3,868,867 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PLPP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38555,424,854 - 55,534,964 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl555,424,854 - 55,534,969 (-)EnsemblGRCh38hg38GRCh38
GRCh37554,720,682 - 54,830,792 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36554,756,439 - 54,866,630 (-)NCBINCBI36Build 36hg18NCBI36
Build 34554,756,441 - 54,866,630NCBI
Celera551,673,499 - 51,784,986 (-)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef551,693,650 - 51,804,240 (-)NCBIHuRef
CHM1_1554,724,563 - 54,834,769 (-)NCBICHM1_1
T2T-CHM13v2.0556,252,163 - 56,362,555 (-)NCBIT2T-CHM13v2.0
Plpp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913112,937,311 - 113,004,428 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13112,937,326 - 113,004,428 (+)EnsemblGRCm39 Ensembl
GRCm3813112,800,777 - 112,867,894 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13112,800,792 - 112,867,894 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713113,591,000 - 113,657,888 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613113,921,670 - 113,988,558 (+)NCBIMGSCv36mm8
Celera13117,114,952 - 117,183,310 (+)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1363.93NCBI
Plpp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8246,172,202 - 46,233,632 (+)NCBIGRCr8
mRatBN7.2244,439,002 - 44,500,430 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl244,438,994 - 44,501,268 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx251,552,134 - 51,613,393 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0249,610,495 - 49,671,753 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0244,485,653 - 44,547,000 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0244,664,076 - 44,726,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl244,664,124 - 44,726,689 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0263,704,421 - 63,767,925 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4244,183,290 - 44,247,787 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1244,111,522 - 44,176,018 (+)NCBI
Celera240,217,653 - 40,278,745 (+)NCBICelera
Cytogenetic Map2q14NCBI
Plpp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544612,229,395 - 12,279,737 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544612,201,678 - 12,279,992 (+)NCBIChiLan1.0ChiLan1.0
PLPP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2458,406,345 - 58,516,396 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1556,560,006 - 56,670,025 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0558,495,348 - 58,605,309 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1560,150,260 - 60,228,157 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl560,160,274 - 60,227,806 (+)Ensemblpanpan1.1panPan2
PLPP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1242,761,712 - 42,854,515 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl242,763,026 - 42,854,802 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha239,806,419 - 39,902,878 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0243,224,892 - 43,322,003 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl243,226,839 - 43,322,180 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1240,303,269 - 40,400,338 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0241,105,130 - 41,201,661 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0241,925,546 - 42,022,369 (-)NCBIUU_Cfam_GSD_1.0
Plpp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213203,328,791 - 203,421,183 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648012,265,246 - 12,359,450 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648012,265,304 - 12,357,747 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLPP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1634,600,719 - 34,744,437 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11634,604,367 - 34,741,524 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21636,713,167 - 36,857,699 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLPP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1451,667,336 - 51,777,016 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl451,667,684 - 51,776,981 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666049543,552 - 652,675 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000027380   ⟹   ENSHGLP00000027139
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247593,780,826 - 3,868,869 (+)Ensembl
RefSeq Acc Id: XM_004848515   ⟹   XP_004848572
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247593,780,910 - 3,868,867 (+)NCBI
RefSeq Acc Id: XM_004848516   ⟹   XP_004848573
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247593,780,904 - 3,868,867 (+)NCBI
RefSeq Acc Id: XM_021261419   ⟹   XP_021117078
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247593,798,753 - 3,868,867 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004848572 (Get FASTA)   NCBI Sequence Viewer  
  XP_004848573 (Get FASTA)   NCBI Sequence Viewer  
  XP_021117078 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB16431 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000027139
  ENSHGLP00100041213
GenBank Protein JAO01669 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004848573   ⟸   XM_004848516
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004848572   ⟸   XM_004848515
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JXB0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117078   ⟸   XM_021261419
- Peptide Label: isoform X3
RefSeq Acc Id: ENSHGLP00000027139   ⟸   ENSHGLT00000027380


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019302 Ensembl, ENTREZGENE
  ENSHGLG00100037477 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000027380 ENTREZGENE
  ENSHGLT00100084047 UniProtKB/TrEMBL
Gene3D-CATH Phosphatidic acid phosphatase type 2/haloperoxidase UniProtKB/TrEMBL
InterPro P_Acid_Pase_2/haloperoxi_sf UniProtKB/TrEMBL
  P_Acid_Pase_2/haloperoxidase UniProtKB/TrEMBL
  PLPP UniProtKB/TrEMBL
KEGG Report hgl:101724889 UniProtKB/TrEMBL
NCBI Gene Plpp1 ENTREZGENE
PANTHER PTHR10165 UniProtKB/TrEMBL
  PTHR10165:SF26 UniProtKB/TrEMBL
Pfam PAP2 UniProtKB/TrEMBL
SMART acidPPc UniProtKB/TrEMBL
Superfamily-SCOP SSF48317 UniProtKB/TrEMBL
UniProt A0A0P6JXB0 ENTREZGENE, UniProtKB/TrEMBL