Lins1 (lines homolog 1) - Rat Genome Database

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Gene: Lins1 (lines homolog 1) Heterocephalus glaber
Analyze
Symbol: Lins1 (Ensembl: LINS)
Name: lines homolog 1
RGD ID: 18904028
Description: INVOLVED IN cognition (inferred); ASSOCIATED WITH autosomal recessive intellectual developmental disorder 27 (ortholog); chromosome 15q26-qter deletion syndrome (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Lines-like protein 1; LINS; protein Lines homolog; protein Lines homolog 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247684,134,796 - 4,145,137 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247684,122,981 - 4,143,202 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cognition  (IEA)

References
Additional References at PubMed
PMID:21993625  


Genomics

Comparative Map Data
Lins1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247684,134,796 - 4,145,137 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247684,122,981 - 4,143,202 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LINS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3815100,566,924 - 100,602,184 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl15100,559,369 - 100,603,230 (-)EnsemblGRCh38hg38GRCh38
GRCh3715101,107,129 - 101,142,389 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361598,926,958 - 98,959,927 (-)NCBINCBI36Build 36hg18NCBI36
Celera1577,522,681 - 77,555,652 (-)NCBICelera
Cytogenetic Map15q26.3NCBI
HuRef1577,231,194 - 77,263,814 (-)NCBIHuRef
CHM1_115100,949,360 - 100,983,431 (-)NCBICHM1_1
T2T-CHM13v2.01598,321,577 - 98,357,861 (-)NCBIT2T-CHM13v2.0
Lins1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39766,339,565 - 66,367,004 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl766,339,637 - 66,367,004 (+)EnsemblGRCm39 Ensembl
GRCm38766,689,817 - 66,717,256 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl766,689,889 - 66,717,256 (+)EnsemblGRCm38mm10GRCm38
MGSCv37773,852,990 - 73,859,542 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36766,587,054 - 66,593,606 (+)NCBIMGSCv36mm8
Celera764,161,477 - 64,168,020 (+)NCBICelera
Cytogenetic Map7CNCBI
cM Map736.08NCBI
Lins1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81129,677,815 - 129,705,399 (+)NCBIGRCr8
mRatBN7.21120,267,586 - 120,295,013 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1120,267,693 - 120,293,607 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1128,265,667 - 128,291,649 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01135,437,099 - 135,463,081 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01128,241,271 - 128,267,234 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01127,599,647 - 127,625,583 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,604,197 - 127,625,577 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01128,674,717 - 128,701,711 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41121,162,852 - 121,169,099 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11121,241,784 - 121,247,350 (+)NCBI
Celera1112,470,441 - 112,496,377 (+)NCBICelera
Cytogenetic Map1q22NCBI
Lins1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541627,586,257 - 27,595,117 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541627,585,172 - 27,609,780 (-)NCBIChiLan1.0ChiLan1.0
LINS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21690,160,094 - 90,194,720 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11593,859,699 - 93,895,045 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01579,293,426 - 79,328,691 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11598,583,906 - 98,616,407 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1598,583,906 - 98,616,407 (-)Ensemblpanpan1.1panPan2
LINS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1340,415,599 - 40,437,075 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl340,415,163 - 40,436,966 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha343,107,942 - 43,128,495 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0340,816,058 - 40,837,558 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl340,816,412 - 40,837,546 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1340,349,850 - 40,371,337 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0340,580,455 - 40,601,936 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0340,787,712 - 40,809,208 (+)NCBIUU_Cfam_GSD_1.0
LINS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1139,168,785 - 139,191,163 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11139,168,859 - 139,191,238 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21155,373,215 - 155,395,580 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LINS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12919,036,427 - 19,065,361 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2919,036,305 - 19,044,244 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605927,478,584 - 27,507,513 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000020922   ⟹   ENSHGLP00000020719
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247684,134,796 - 4,145,137 (+)Ensembl
RefSeq Acc Id: XM_004852678   ⟹   XP_004852735
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247684,122,981 - 4,143,202 (+)NCBI
RefSeq Acc Id: XM_004852679   ⟹   XP_004852736
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247684,123,195 - 4,143,202 (+)NCBI
RefSeq Acc Id: XM_021264745   ⟹   XP_021120404
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247684,124,536 - 4,143,202 (+)NCBI
RefSeq Acc Id: XM_021264746   ⟹   XP_021120405
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247684,123,352 - 4,143,202 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004852735 (Get FASTA)   NCBI Sequence Viewer  
  XP_004852736 (Get FASTA)   NCBI Sequence Viewer  
  XP_021120404 (Get FASTA)   NCBI Sequence Viewer  
  XP_021120405 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA99798 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020719
  ENSHGLP00000054145
  ENSHGLP00100022040
GenBank Protein JAN98864 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004852735   ⟸   XM_004852678
- Peptide Label: isoform X1
- UniProtKB: G5ARY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004852736   ⟸   XM_004852679
- Peptide Label: isoform X1
- UniProtKB: G5ARY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120405   ⟸   XM_021264746
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021120404   ⟸   XM_021264745
- Peptide Label: isoform X1
- UniProtKB: G5ARY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000020719   ⟸   ENSHGLT00000020922


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014821 Ensembl, ENTREZGENE
  ENSHGLG00000034641 UniProtKB/TrEMBL
  ENSHGLG00100016224 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000020922 ENTREZGENE
  ENSHGLT00000086372 UniProtKB/TrEMBL
  ENSHGLT00100022268 UniProtKB/TrEMBL
InterPro Lines_C UniProtKB/TrEMBL
  LINES_N UniProtKB/TrEMBL
  Protein_Lines UniProtKB/TrEMBL
KEGG Report hgl:101701983 UniProtKB/TrEMBL
NCBI Gene Lins1 ENTREZGENE
PANTHER PROTEIN LINES HOMOLOG 1 UniProtKB/TrEMBL
  PTHR16057 UniProtKB/TrEMBL
Pfam LINES_C UniProtKB/TrEMBL
  LINES_N UniProtKB/TrEMBL
UniProt G5ARY8 ENTREZGENE, UniProtKB/TrEMBL