Sst (somatostatin) - Rat Genome Database

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Pathways
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Gene: Sst (somatostatin) Heterocephalus glaber
Analyze
Symbol: Sst
Name: somatostatin
RGD ID: 18903596
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN hyperosmotic response (ortholog); regulation of cell migration (ortholog); regulation of postsynaptic membrane neurotransmitter receptor levels (ortholog); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynamics pathway; ASSOCIATED WITH Barrett's esophagus (ortholog); disease of cellular proliferation (ortholog); endometriosis (ortholog); FOUND IN cytosol (ortholog); extracellular space (ortholog); GABA-ergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: somatostatin preproprotein
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473069,213,781 - 69,215,477 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473069,213,917 - 69,215,296 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Sst
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473069,213,781 - 69,215,477 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473069,213,917 - 69,215,296 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SST
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383187,668,912 - 187,670,394 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3187,668,912 - 187,670,394 (-)EnsemblGRCh38hg38GRCh38
GRCh373187,386,700 - 187,388,182 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363188,869,388 - 188,870,895 (-)NCBINCBI36Build 36hg18NCBI36
Build 343188,869,406 - 188,870,808NCBI
Celera3185,817,667 - 185,819,174 (-)NCBICelera
Cytogenetic Map3q27.3NCBI
HuRef3184,791,007 - 184,792,514 (-)NCBIHuRef
CHM1_13187,349,954 - 187,351,461 (-)NCBICHM1_1
T2T-CHM13v2.03190,486,363 - 190,487,845 (-)NCBIT2T-CHM13v2.0
Sst
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391623,708,327 - 23,710,041 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1623,708,323 - 23,709,708 (-)EnsemblGRCm39 Ensembl
GRCm381623,889,573 - 23,891,342 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1623,889,573 - 23,890,958 (-)EnsemblGRCm38mm10GRCm38
MGSCv371623,889,667 - 23,890,930 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361623,804,930 - 23,806,193 (-)NCBIMGSCv36mm8
Celera1624,439,585 - 24,440,848 (-)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1615.0NCBI
Sst
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,461,546 - 90,462,823 (+)NCBIGRCr8
mRatBN7.21176,956,896 - 76,958,173 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1176,956,896 - 76,958,173 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1185,714,888 - 85,716,167 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01178,350,097 - 78,351,376 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01177,429,193 - 77,430,472 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01180,358,172 - 80,359,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1180,358,211 - 80,359,444 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01180,374,262 - 80,375,447 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41179,125,031 - 79,126,216 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11179,182,619 - 79,183,805 (+)NCBI
Celera1175,836,256 - 75,837,533 (+)NCBICelera
RH 3.4 Map11640.6RGD
Cytogenetic Map11q23NCBI
SST
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22185,539,811 - 185,541,321 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13185,544,525 - 185,546,059 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03184,695,561 - 184,697,091 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13193,156,526 - 193,158,020 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3193,155,363 - 193,158,337 (-)Ensemblpanpan1.1panPan2
SST
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13420,063,091 - 20,064,520 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3420,063,090 - 20,064,557 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3424,155,973 - 24,157,402 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03419,983,105 - 19,984,534 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3419,983,111 - 19,984,571 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13420,011,742 - 20,013,171 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03420,005,493 - 20,006,922 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03420,245,365 - 20,246,794 (-)NCBIUU_Cfam_GSD_1.0
Sst
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602116,372,454 - 116,373,819 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365782,464,212 - 2,465,701 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365782,464,310 - 2,465,673 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SST
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13125,337,418 - 125,338,850 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113125,337,560 - 125,338,742 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213134,621,119 - 134,622,301 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SST
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11581,946,287 - 81,947,775 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1581,946,206 - 81,947,790 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604155,444,092 - 55,445,581 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000027182   ⟹   ENSHGLP00000026943
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473069,213,781 - 69,215,477 (+)Ensembl
RefSeq Acc Id: XM_004834804   ⟹   XP_004834861
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473069,213,917 - 69,215,296 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004834861 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB12496 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000026943
GenBank Protein JAN96068 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004834861   ⟸   XM_004834804
- UniProtKB: G5BTD2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000026943   ⟸   ENSHGLT00000027182


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019161 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000027182 ENTREZGENE, UniProtKB/TrEMBL
InterPro Somatostatin UniProtKB/TrEMBL
  Somatostatin/Cortistatin_C UniProtKB/TrEMBL
NCBI Gene Sst ENTREZGENE
PANTHER PTHR10558 UniProtKB/TrEMBL
  SOMATOSTATIN UniProtKB/TrEMBL
Pfam Somatostatin UniProtKB/TrEMBL
PIRSF Somatostatin UniProtKB/TrEMBL
UniProt G5BTD2 ENTREZGENE, UniProtKB/TrEMBL