Fth1 (ferritin heavy chain 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Fth1 (ferritin heavy chain 1) Heterocephalus glaber
Analyze
Symbol: Fth1
Name: ferritin heavy chain 1
RGD ID: 18902567
Description: ENCODES a protein that exhibits ferroxidase activity (ortholog); identical protein binding (ortholog); iron ion binding (ortholog); INVOLVED IN iron ion transport (ortholog); negative regulation of cellular process (ortholog); negative regulation of ferroptosis (ortholog); PARTICIPATES IN iron storage pathway; ASSOCIATED WITH autosomal dominant vitreoretinochoroidopathy (ortholog); bestrophinopathy (ortholog); Chronic Cerebral Hypoperfusion (ortholog); FOUND IN autolysosome (ortholog); cytosol (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ferritin heavy chain
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624926469,870 - 471,142 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
autolysosome  (ISO)
cytoplasm  (IEA)
cytosol  (ISO)
membrane  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:26763976   PMID:30032202  


Genomics

Comparative Map Data
Fth1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624926469,870 - 471,142 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FTH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,964,285 - 61,967,634 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,959,718 - 61,967,634 (-)EnsemblGRCh38hg38GRCh38
GRCh371161,731,757 - 61,735,106 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361161,488,333 - 61,491,708 (-)NCBINCBI36Build 36hg18NCBI36
Build 341161,488,334 - 61,491,708NCBI
Celera1159,067,058 - 59,070,433 (-)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,059,745 - 58,063,103 (-)NCBIHuRef
CHM1_11161,614,953 - 61,618,328 (-)NCBICHM1_1
T2T-CHM13v2.01161,953,110 - 61,956,459 (-)NCBIT2T-CHM13v2.0
Fth1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39199,957,964 - 9,962,475 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl199,957,962 - 9,962,462 (+)EnsemblGRCm39 Ensembl
GRCm38199,980,600 - 9,985,111 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl199,980,598 - 9,985,098 (+)EnsemblGRCm38mm10GRCm38
MGSCv371910,057,193 - 10,059,582 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361910,049,748 - 10,052,137 (+)NCBIMGSCv36mm8
Celera1910,680,030 - 10,682,419 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.23NCBI
Fth1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,052,037 - 216,054,325 (+)NCBIGRCr8
mRatBN7.21206,627,142 - 206,629,430 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1206,627,103 - 206,725,424 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,005,534 - 215,007,822 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,060,660 - 222,062,948 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01214,755,668 - 214,757,956 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01226,030,940 - 226,033,228 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,030,938 - 226,033,228 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01232,979,122 - 232,981,410 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,430,453 - 212,432,741 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11212,588,882 - 212,591,171 (+)NCBI
Celera1204,122,676 - 204,124,964 (+)NCBICelera
RH 3.4 Map14258.8RGD
Cytogenetic Map1q43NCBI
Fth1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555115,771,777 - 5,773,112 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555115,772,374 - 5,773,224 (+)NCBIChiLan1.0ChiLan1.0
FTH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2963,197,979 - 63,203,292 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11164,241,728 - 64,244,902 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01157,329,163 - 57,332,248 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11160,687,517 - 60,690,080 (-)NCBIpanpan1.1PanPan1.1panPan2
FTH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11854,466,167 - 54,468,733 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1854,466,023 - 54,468,732 (+)EnsemblCanFam3.1canFam3CanFam3.1
UMICH_Zoey_3.12832,593,900 - 32,594,536 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02832,618,740 - 32,619,377 (-)NCBIUNSW_CanFamBas_1.0
Fth1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494711,005,083 - 11,006,769 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365811,118,905 - 1,120,592 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FTH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.129,535,051 - 9,537,979 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,983,179 - 8,986,091 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FTH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,837,533 - 11,840,926 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038109,211,114 - 109,214,623 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NM_001310304   ⟹   NP_001297233
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624926469,870 - 471,142 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001297233 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AIZ08992 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000004977
Reference Protein Sequences
RefSeq Acc Id: NP_001297233   ⟸   NM_001310304
- UniProtKB: A0A0A7HRF9 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003647 ENTREZGENE
Ensembl Transcript ENSHGLT00000005041 ENTREZGENE
Gene3D-CATH 1.20.1260.10 UniProtKB/TrEMBL
InterPro Ferritin UniProtKB/TrEMBL
  Ferritin-like UniProtKB/TrEMBL
  Ferritin-like_diiron UniProtKB/TrEMBL
  Ferritin-like_SF UniProtKB/TrEMBL
  Ferritin_CS UniProtKB/TrEMBL
  Ferritin_DPS_dom UniProtKB/TrEMBL
KEGG Report hgl:101723628 UniProtKB/TrEMBL
NCBI Gene Fth1 ENTREZGENE
PANTHER FERRITIN HEAVY CHAIN UniProtKB/TrEMBL
  PTHR11431 UniProtKB/TrEMBL
Pfam Ferritin UniProtKB/TrEMBL
PROSITE FERRITIN_1 UniProtKB/TrEMBL
  FERRITIN_2 UniProtKB/TrEMBL
  FERRITIN_LIKE UniProtKB/TrEMBL
Superfamily-SCOP SSF47240 UniProtKB/TrEMBL
UniProt A0A0A7HRF9 ENTREZGENE, UniProtKB/TrEMBL