Sap25 (Sin3A associated protein 25) - Rat Genome Database

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Gene: Sap25 (Sin3A associated protein 25) Heterocephalus glaber
Analyze
Symbol: Sap25
Name: Sin3A associated protein 25
RGD ID: 18900114
Description: INVOLVED IN negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone deacetylase complex subunit SAP25
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,504,070 - 16,505,445 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,503,994 - 16,505,554 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Sap25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,504,070 - 16,505,445 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,503,994 - 16,505,554 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SAP25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,572,228 - 100,573,900 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,572,228 - 100,573,900 (-)EnsemblGRCh38hg38GRCh38
GRCh377100,169,851 - 100,171,523 (-)NCBIGRCh37GRCh37hg19GRCh37
Celera794,899,650 - 94,901,069 (-)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,801,523 - 94,802,942 (-)NCBIHuRef
CHM1_17100,100,425 - 100,101,844 (-)NCBICHM1_1
T2T-CHM13v2.07101,812,311 - 101,813,983 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,529,486 - 99,530,905 (-)NCBI
Sap25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,639,735 - 137,641,164 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,639,596 - 137,641,164 (+)EnsemblGRCm39 Ensembl
GRCm385137,641,473 - 137,642,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,641,334 - 137,642,902 (+)EnsemblGRCm38mm10GRCm38
MGSCv375138,082,701 - 138,084,130 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,082,701 - 138,084,127 (+)NCBIMGSCv36mm8
Celera5134,624,779 - 134,626,207 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.59NCBI
Sap25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81224,692,548 - 24,693,683 (-)NCBIGRCr8
mRatBN7.21219,055,762 - 19,057,425 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1219,055,763 - 19,076,089 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01222,125,568 - 22,126,671 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,125,571 - 22,127,021 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,142,944 - 24,144,637 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41219,705,736 - 19,707,247 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1220,861,157 - 20,862,260 (-)NCBICelera
Cytogenetic Map12q12NCBI
Sap25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573328,212 - 329,890 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955573328,212 - 329,897 (+)NCBIChiLan1.0ChiLan1.0
SAP25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,478,268 - 118,485,353 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,748,306 - 166,749,985 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,599,340 - 92,601,029 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17106,001,455 - 106,002,892 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,001,455 - 106,002,918 (-)Ensemblpanpan1.1panPan2
SAP25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,113,955 - 9,115,567 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,114,032 - 9,116,094 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,818,598 - 10,820,173 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.069,048,368 - 9,049,943 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl69,048,411 - 9,050,473 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.168,900,891 - 8,902,466 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.068,878,562 - 8,880,137 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,060,781 - 9,062,356 (+)NCBIUU_Cfam_GSD_1.0
Sap25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,404,444 - 133,406,342 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543630,300 - 631,698 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543629,437 - 632,226 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SAP25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,497,453 - 8,499,154 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,497,449 - 8,500,546 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.237,840,547 - 7,842,272 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SAP25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,639,501 - 12,641,113 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660703,663,647 - 3,665,333 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000025926   ⟹   ENSHGLP00000025698
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474016,504,070 - 16,505,445 (+)Ensembl
RefSeq Acc Id: XM_004840197   ⟹   XP_004840254
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474016,503,997 - 16,505,554 (+)NCBI
RefSeq Acc Id: XM_021254506   ⟹   XP_021110165
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474016,503,994 - 16,505,448 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004840254 (Get FASTA)   NCBI Sequence Viewer  
  XP_021110165 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025698
GenBank Protein JAO01398 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021110165   ⟸   XM_021254506
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004840254   ⟸   XM_004840197
- Peptide Label: isoform X1
- UniProtKB: A0A0N8EU91 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000025698   ⟸   ENSHGLT00000025926


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018294 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000025926 ENTREZGENE
Gene3D-CATH 6.10.140.710 UniProtKB/TrEMBL
InterPro SAP25 UniProtKB/TrEMBL
KEGG Report hgl:101716784 UniProtKB/TrEMBL
NCBI Gene Sap25 ENTREZGENE
PANTHER HISTONE DEACETYLASE COMPLEX SUBUNIT SAP25 UniProtKB/TrEMBL
  PTHR39231 UniProtKB/TrEMBL
Pfam SAP25 UniProtKB/TrEMBL
UniProt A0A0N8EU91 ENTREZGENE, UniProtKB/TrEMBL