ADAMTSL3 (ADAMTS like 3) - Rat Genome Database

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Gene: ADAMTSL3 (ADAMTS like 3) Chlorocebus sabaeus
Analyze
Symbol: ADAMTSL3
Name: ADAMTS like 3
RGD ID: 18736633
Description: ASSOCIATED WITH amenorrhea (ortholog); Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred); intracellular membrane-bounded organelle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ADAMTS-like protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1291,592,205 - 1,974,406 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl291,592,300 - 1,972,722 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605945,139,652 - 45,543,755 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADAMTSL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1291,592,205 - 1,974,406 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl291,592,300 - 1,972,722 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605945,139,652 - 45,543,755 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ADAMTSL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381583,654,123 - 84,039,842 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1583,654,088 - 84,039,842 (+)EnsemblGRCh38hg38GRCh38
GRCh371584,322,875 - 84,708,594 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361582,113,842 - 82,499,598 (+)NCBINCBI36Build 36hg18NCBI36
Celera1559,876,379 - 60,263,640 (-)NCBICelera
Cytogenetic Map15q25.2NCBI
HuRef1560,587,925 - 60,970,977 (+)NCBIHuRef
CHM1_11584,064,478 - 84,450,677 (+)NCBICHM1_1
T2T-CHM13v2.01581,522,060 - 81,905,793 (+)NCBIT2T-CHM13v2.0
Adamtsl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39781,984,612 - 82,263,658 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl781,984,902 - 82,263,658 (+)EnsemblGRCm39 Ensembl
GRCm38782,335,399 - 82,614,450 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl782,335,694 - 82,614,450 (+)EnsemblGRCm38mm10GRCm38
MGSCv37789,484,204 - 89,762,958 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36782,211,352 - 82,490,633 (+)NCBIMGSCv36mm8
Celera779,746,007 - 80,031,344 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map747.18NCBI
Adamtsl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81145,698,004 - 146,006,195 (+)NCBIGRCr8
mRatBN7.21136,288,793 - 136,596,986 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1136,288,793 - 136,596,986 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1144,205,278 - 144,526,290 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01151,374,526 - 151,695,340 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01144,287,413 - 144,601,189 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01144,238,958 - 144,561,065 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1144,239,020 - 144,561,247 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01145,170,122 - 145,490,045 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41138,563,870 - 138,876,886 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11138,630,616 - 138,955,117 (+)NCBI
Celera1128,337,150 - 128,639,093 (+)NCBICelera
Cytogenetic Map1q31NCBI
Adamtsl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541612,820,138 - 13,131,826 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541612,818,153 - 13,132,960 (-)NCBIChiLan1.0ChiLan1.0
ADAMTSL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21671,854,492 - 72,240,503 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11576,013,784 - 76,399,759 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01561,567,731 - 61,953,255 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11581,537,266 - 81,922,308 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1581,538,868 - 81,920,292 (+)Ensemblpanpan1.1panPan2
ADAMTSL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1355,358,869 - 55,695,198 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl355,357,888 - 55,693,167 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha358,007,958 - 58,345,460 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0355,786,002 - 56,123,417 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl355,633,124 - 56,121,658 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1355,293,677 - 55,630,742 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0355,503,341 - 55,840,911 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0355,842,319 - 56,179,637 (+)NCBIUU_Cfam_GSD_1.0
Adamtsl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640127,810,502 - 128,142,952 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648318,193,198 - 18,522,028 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648318,191,568 - 18,523,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAMTSL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl751,006,366 - 51,363,620 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1751,006,356 - 51,363,855 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2756,498,843 - 56,687,446 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Adamtsl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476819,339,106 - 19,691,905 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476819,337,770 - 19,692,425 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 13 60
Below cutoff 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000015402   ⟹   ENSCSAP00000013343
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl291,592,300 - 1,972,722 (-)Ensembl
RefSeq Acc Id: XM_007990199   ⟹   XP_007988390
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1291,592,205 - 1,974,406 (-)NCBI
Vero_WHO_p1.0NW_02366605945,139,652 - 45,543,755 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007990200   ⟹   XP_007988391
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1291,592,205 - 1,974,406 (-)NCBI
Vero_WHO_p1.0NW_02366605945,139,652 - 45,543,755 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037987795   ⟹   XP_037843723
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605945,176,339 - 45,543,755 (+)NCBI
RefSeq Acc Id: XM_037987796   ⟹   XP_037843724
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605945,176,339 - 45,543,755 (+)NCBI
RefSeq Acc Id: XM_037987797   ⟹   XP_037843725
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605945,174,785 - 45,543,755 (+)NCBI
RefSeq Acc Id: XM_037987798   ⟹   XP_037843726
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605945,176,339 - 45,543,755 (+)NCBI
RefSeq Acc Id: XM_037987799   ⟹   XP_037843727
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605945,176,339 - 45,543,755 (+)NCBI
RefSeq Acc Id: XM_037987800   ⟹   XP_037843728
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605945,176,339 - 45,543,755 (+)NCBI
RefSeq Acc Id: XM_037987801   ⟹   XP_037843729
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605945,176,339 - 45,540,882 (+)NCBI
RefSeq Acc Id: XM_037987802   ⟹   XP_037843730
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605945,176,339 - 45,508,424 (+)NCBI
RefSeq Acc Id: XM_037987803   ⟹   XP_037843731
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605945,176,339 - 45,396,300 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007988391   ⟸   XM_007990200
- Peptide Label: isoform X8
- UniProtKB: A0A0D9RXK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007988390   ⟸   XM_007990199
- Peptide Label: isoform X7
- UniProtKB: A0A0D9RXK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000013343   ⟸   ENSCSAT00000015402
RefSeq Acc Id: XP_037843725   ⟸   XM_037987797
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RXK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843726   ⟸   XM_037987798
- Peptide Label: isoform X4
- UniProtKB: A0A0D9RXK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843723   ⟸   XM_037987795
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RXK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843724   ⟸   XM_037987796
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RXK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843727   ⟸   XM_037987799
- Peptide Label: isoform X5
- UniProtKB: A0A0D9RXK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843728   ⟸   XM_037987800
- Peptide Label: isoform X6
- UniProtKB: A0A0D9RXK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843729   ⟸   XM_037987801
- Peptide Label: isoform X9
- UniProtKB: A0A0D9RXK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037843730   ⟸   XM_037987802
- Peptide Label: isoform X10
RefSeq Acc Id: XP_037843731   ⟸   XM_037987803
- Peptide Label: isoform X11


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017309 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015402.1 UniProtKB/TrEMBL
Gene3D-CATH 2.20.100.10 UniProtKB/TrEMBL
  2.60.120.830 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
NCBI Gene ADAMTSL3 ENTREZGENE
PANTHER ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE UniProtKB/TrEMBL
  ADAMTS-LIKE PROTEIN 3 UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1_ADAMTS UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF82895 UniProtKB/TrEMBL
UniProt A0A0D9RXK4 ENTREZGENE, UniProtKB/TrEMBL