EHMT1 (euchromatic histone lysine methyltransferase 1) - Rat Genome Database

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Gene: EHMT1 (euchromatic histone lysine methyltransferase 1) Chlorocebus sabaeus
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Symbol: EHMT1
Name: euchromatic histone lysine methyltransferase 1
RGD ID: 18728214
Description: ENCODES a protein that exhibits C2H2 zinc finger domain binding (inferred); histone H3 methyltransferase activity (inferred); histone H3K27 methyltransferase activity (inferred); INVOLVED IN DNA methylation-dependent heterochromatin formation (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); response to fungicide (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); Adams-Oliver Syndrome 5 (ortholog); autistic disorder (ortholog); FOUND IN chromatin (inferred); chromosome (inferred); nuclear body (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone-lysine N-methyltransferase EHMT1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112380,041 - 545,333 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12379,943 - 497,033 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660584,899,940 - 5,005,236 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IEA)
chromosome  (IEA)
nuclear body  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EHMT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112380,041 - 545,333 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12379,943 - 497,033 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660584,899,940 - 5,005,236 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
EHMT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389137,619,005 - 137,836,127 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9137,618,992 - 137,870,016 (+)EnsemblGRCh38hg38GRCh38
GRCh379140,513,457 - 140,730,579 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,725,238 - 139,850,400 (+)NCBINCBI36Build 36hg18NCBI36
Build 349137,881,253 - 138,006,413NCBI
Celera9111,130,415 - 111,256,878 (+)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,975,406 - 110,193,755 (+)NCBIHuRef
CHM1_19140,662,174 - 140,878,710 (+)NCBICHM1_1
T2T-CHM13v2.09149,870,687 - 150,093,989 (+)NCBIT2T-CHM13v2.0
Ehmt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39224,680,781 - 24,809,658 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl224,679,940 - 24,809,626 (-)EnsemblGRCm39 Ensembl
GRCm38224,790,769 - 24,919,643 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl224,789,928 - 24,919,614 (-)EnsemblGRCm38mm10GRCm38
MGSCv37224,646,293 - 24,742,591 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36224,612,804 - 24,741,610 (-)NCBIMGSCv36mm8
Celera224,513,068 - 24,641,644 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map216.73NCBI
Ehmt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8327,978,888 - 28,127,178 (-)NCBIGRCr8
mRatBN7.237,580,680 - 7,729,046 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl37,580,683 - 7,729,007 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx310,684,555 - 10,777,264 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,270,788 - 19,363,493 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0317,460,616 - 17,553,324 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.031,966,974 - 2,123,858 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl31,960,957 - 2,123,820 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.031,951,004 - 2,106,608 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,074,136 - 3,169,921 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.133,074,159 - 3,225,936 (-)NCBI
Celera32,411,864 - 2,558,168 (-)NCBICelera
Cytogenetic Map3p13NCBI
Ehmt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555135,547,313 - 5,641,499 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555135,491,446 - 5,642,559 (+)NCBIChiLan1.0ChiLan1.0
EHMT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2111,508,542 - 1,735,451 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan191,510,875 - 1,737,763 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09108,724,568 - 108,951,077 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19137,699,213 - 137,895,564 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9137,764,950 - 137,895,564 (+)Ensemblpanpan1.1panPan2
EHMT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,031,593 - 48,110,954 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,032,709 - 48,175,828 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha947,218,499 - 47,362,742 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0948,893,204 - 49,037,678 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl948,893,199 - 49,037,650 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1947,669,581 - 47,813,979 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0947,968,987 - 48,113,126 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,015,199 - 48,159,643 (-)NCBIUU_Cfam_GSD_1.0
Ehmt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,924,820 - 203,053,478 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936669321,249 - 423,018 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936669321,580 - 450,061 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EHMT1
(Sus scrofa - pig)		 No map positions available.
Ehmt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624760272,493 - 379,780 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624760271,397 - 463,462 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 2 43
Low 18 17
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000014955   ⟹   ENSCSAP00000012911
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl12379,943 - 497,033 (-)Ensembl
RefSeq Acc Id: XM_037987065   ⟹   XP_037842993
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660584,899,940 - 5,005,236 (+)NCBI
RefSeq Acc Id: XM_037987066   ⟹   XP_037842994
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660584,899,940 - 5,005,236 (+)NCBI
RefSeq Acc Id: XM_037987067   ⟹   XP_037842995
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660584,915,268 - 5,005,236 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037842993 (Get FASTA)   NCBI Sequence Viewer  
  XP_037842994 (Get FASTA)   NCBI Sequence Viewer  
  XP_037842995 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012911.1
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000012911   ⟸   ENSCSAT00000014955
RefSeq Acc Id: XP_037842994   ⟸   XM_037987066
- Peptide Label: isoform X2
RefSeq Acc Id: XP_037842993   ⟸   XM_037987065
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037842995   ⟸   XM_037987067
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016860 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014955.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  2.170.270.10 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  EHMT1 UniProtKB/TrEMBL
  EHMT1/EHMT2 UniProtKB/TrEMBL
  EHMT_ZBD UniProtKB/TrEMBL
  Pre-SET_dom UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
NCBI Gene EHMT1 ENTREZGENE
PANTHER PTHR46307 UniProtKB/TrEMBL
  PTHR46307:SF2 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
  EHMT1-2_CRR UniProtKB/TrEMBL
  Pre-SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  PRE_SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  PreSET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A0D9RWC2_CHLSB UniProtKB/TrEMBL