KNG1 (kininogen 1) - Rat Genome Database

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Gene: KNG1 (kininogen 1) Chlorocebus sabaeus
Analyze
Symbol: KNG1
Name: kininogen 1
RGD ID: 18695708
Description: ENCODES a protein that exhibits hormone activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN negative regulation of cell adhesion (ortholog); negative regulation of proteolysis (ortholog); PARTICIPATES IN kallikrein-kinin cascade pathway; kinin signaling pathway; syndecan signaling pathway; ASSOCIATED WITH 3MC syndrome 1 (ortholog); acquired angioedema (ortholog); acute kidney failure (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kininogen-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11581,002,287 - 81,027,893 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604154,492,596 - 54,518,121 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KNG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11581,002,287 - 81,027,893 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604154,492,596 - 54,518,121 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
KNG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,717,359 - 186,744,410 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3186,717,348 - 186,744,410 (+)EnsemblGRCh38hg38GRCh38
GRCh373186,435,148 - 186,462,199 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,917,814 - 187,944,437 (+)NCBINCBI36Build 36hg18NCBI36
Celera3184,871,536 - 184,898,662 (+)NCBICelera
Cytogenetic Map3q27.3NCBI
HuRef3183,844,775 - 183,871,713 (+)NCBIHuRef
CHM1_13186,399,036 - 186,425,781 (+)NCBICHM1_1
T2T-CHM13v2.03189,539,122 - 189,566,165 (+)NCBIT2T-CHM13v2.0
Kng2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,804,602 - 22,847,851 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1622,804,604 - 22,848,232 (-)EnsemblGRCm39 Ensembl
GRCm381622,985,852 - 23,029,101 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1622,985,854 - 23,029,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv371622,985,925 - 23,029,174 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361622,902,680 - 22,944,351 (-)NCBIMGSCv36mm8
Celera1623,545,793 - 23,588,919 (-)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.82NCBI
Kng2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,418,470 - 91,440,841 (+)NCBIGRCr8
mRatBN7.21177,913,876 - 77,936,247 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1177,909,612 - 78,002,971 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1186,664,319 - 86,686,690 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,302,200 - 79,324,460 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01178,378,641 - 78,401,008 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01181,509,185 - 81,516,759 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01184,605,412 - 84,612,986 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41180,109,499 - 80,131,887 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11180,167,317 - 80,189,475 (+)NCBI
Celera1176,789,106 - 76,811,459 (+)NCBICelera
Cytogenetic Map11q23NCBI
Kng1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542020,989,197 - 21,016,084 (-)NCBIChiLan1.0ChiLan1.0
KNG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22184,593,336 - 184,620,177 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13184,598,051 - 184,624,892 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03183,751,598 - 183,778,655 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13192,219,675 - 192,245,318 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3192,219,462 - 192,245,149 (+)Ensemblpanpan1.1panPan2
KNG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13419,288,629 - 19,318,096 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3419,287,109 - 19,318,081 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3423,373,992 - 23,403,581 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03419,199,856 - 19,229,431 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3419,199,904 - 19,229,419 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13419,231,763 - 19,260,578 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03419,231,843 - 19,260,884 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03419,460,203 - 19,488,753 (+)NCBIUU_Cfam_GSD_1.0
Kng1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,161,767 - 117,189,596 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365783,253,749 - 3,281,296 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365783,255,335 - 3,281,296 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KNG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13124,521,340 - 124,557,958 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113124,521,276 - 124,557,384 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213133,911,227 - 133,947,757 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Kng1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473070,022,449 - 70,065,115 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_038003051   ⟹   XP_037858979
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604154,492,596 - 54,518,121 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037858979 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000005514.1
Reference Protein Sequences
RefSeq Acc Id: XP_037858979   ⟸   XM_038003051
- UniProtKB: A0A0D9RA75 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009254 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000007328.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.450.10 UniProtKB/TrEMBL
InterPro Cystatin_dom UniProtKB/TrEMBL
  Cystatin_sf UniProtKB/TrEMBL
  Kininogen-type_cystatin_dom UniProtKB/TrEMBL
  Prot_inh_cystat_CS UniProtKB/TrEMBL
NCBI Gene KNG1 ENTREZGENE
PANTHER FETUIN UniProtKB/TrEMBL
  KININOGEN-1 UniProtKB/TrEMBL
Pfam Cystatin UniProtKB/TrEMBL
PROSITE CYSTATIN UniProtKB/TrEMBL
  CYSTATIN_KININOGEN UniProtKB/TrEMBL
SMART SM00043 UniProtKB/TrEMBL
Superfamily-SCOP Cystatin/monellin UniProtKB/TrEMBL
UniProt A0A0D9RA75 ENTREZGENE, UniProtKB/TrEMBL