IRF9 (interferon regulatory factor 9) - Rat Genome Database

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Gene: IRF9 (interferon regulatory factor 9) Chlorocebus sabaeus
Analyze
Symbol: IRF9
Name: interferon regulatory factor 9
RGD ID: 18661549
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN immune system process (inferred); positive regulation of transcription by RNA polymerase II (inferred); regulation of DNA-templated transcription (inferred); PARTICIPATES IN type II interferon signaling pathway; ASSOCIATED WITH acute pancreatitis (ortholog); Brain-Lung-Thyroid Syndrome (ortholog); Experimental Colitis (ortholog); FOUND IN ISGF3 complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,146,116 - 1,151,622 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,146,618 - 1,151,546 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,828,805 - 12,834,326 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
ISGF3 complex  (IEA,ISO)
nucleus  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IRF9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,146,116 - 1,151,622 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,146,618 - 1,151,546 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,828,805 - 12,834,326 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
IRF9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,161,265 - 24,166,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,161,234 - 24,168,043 (+)EnsemblGRCh38hg38GRCh38
GRCh371424,630,474 - 24,635,774 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,700,262 - 23,705,614 (+)NCBINCBI36Build 36hg18NCBI36
Build 341423,700,363 - 23,705,612NCBI
Celera144,494,890 - 4,500,242 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef144,745,386 - 4,750,738 (+)NCBIHuRef
CHM1_11424,629,072 - 24,634,424 (+)NCBICHM1_1
T2T-CHM13v2.01418,359,574 - 18,364,874 (+)NCBIT2T-CHM13v2.0
Irf9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,841,442 - 55,847,487 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,841,028 - 55,847,487 (+)EnsemblGRCm39 Ensembl
GRCm381455,603,985 - 55,610,030 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,603,571 - 55,610,030 (+)EnsemblGRCm38mm10GRCm38
MGSCv371456,222,822 - 56,228,867 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,558,650 - 54,564,101 (+)NCBIMGSCv36mm8
Celera1453,409,045 - 53,415,090 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Irf9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,065,422 - 33,071,881 (+)NCBIGRCr8
mRatBN7.21529,095,474 - 29,101,924 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,095,789 - 29,101,236 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,941,593 - 30,946,796 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01532,088,791 - 32,093,994 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,331,133 - 30,336,336 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,282,936 - 34,288,981 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,282,936 - 34,288,138 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,172,683 - 38,179,176 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,739,755 - 33,744,958 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,755,454 - 33,760,657 (+)NCBI
Celera1528,671,799 - 28,677,002 (+)NCBICelera
Cytogenetic Map15p13NCBI
Irf9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,234,077 - 36,239,500 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,233,633 - 36,239,916 (-)NCBIChiLan1.0ChiLan1.0
IRF9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,515,160 - 25,520,969 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,731,654 - 24,737,461 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,937,068 - 4,942,870 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11423,061,994 - 23,067,824 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,061,990 - 23,067,824 (+)Ensemblpanpan1.1panPan2
IRF9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,152,146 - 4,157,201 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha84,073,839 - 4,078,885 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,262,726 - 4,267,771 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,252,109 - 4,302,591 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,953,354 - 3,958,397 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.084,015,093 - 4,020,132 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,277,257 - 4,282,303 (+)NCBIUU_Cfam_GSD_1.0
Irf9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864036,003,032 - 36,008,793 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722380,572 - 384,372 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722380,193 - 385,887 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IRF9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,126,622 - 75,139,640 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,133,800 - 75,139,641 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,405,098 - 80,410,938 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Irf9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,370,289 - 8,376,950 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,369,830 - 8,376,593 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 20 42
Low 18
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000014146   ⟹   ENSCSAP00000012125
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl241,146,618 - 1,151,546 (+)Ensembl
RefSeq Acc Id: XM_007986291   ⟹   XP_007984482
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1241,146,116 - 1,151,622 (+)NCBI
Vero_WHO_p1.0NW_02366603612,828,805 - 12,834,326 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007986292   ⟹   XP_007984483
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1241,146,727 - 1,151,622 (+)NCBI
Vero_WHO_p1.0NW_02366603612,829,460 - 12,834,326 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007986293   ⟹   XP_007984484
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1241,146,116 - 1,151,622 (+)NCBI
Vero_WHO_p1.0NW_02366603612,828,810 - 12,834,326 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007984482 (Get FASTA)   NCBI Sequence Viewer  
  XP_007984483 (Get FASTA)   NCBI Sequence Viewer  
  XP_007984484 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000012125.1
Reference Protein Sequences
RefSeq Acc Id: XP_007984482   ⟸   XM_007986291
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007984484   ⟸   XM_007986293
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RU36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007984483   ⟸   XM_007986292
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCSAP00000012125   ⟸   ENSCSAT00000014146


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016071 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014146.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  2.60.200.10 UniProtKB/TrEMBL
InterPro Interferon_reg_fac_CS UniProtKB/TrEMBL
  Interferon_reg_fact_DNA-bd_dom UniProtKB/TrEMBL
  Interferon_reg_factor-3 UniProtKB/TrEMBL
  SMAD-like_dom_sf UniProtKB/TrEMBL
  SMAD_FHA_dom_sf UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene IRF9 ENTREZGENE
PANTHER INTERFERON REGULATORY FACTOR UniProtKB/TrEMBL
  INTERFERON REGULATORY FACTOR 9 UniProtKB/TrEMBL
Pfam IRF UniProtKB/TrEMBL
  IRF-3 UniProtKB/TrEMBL
PRINTS INTFRNREGFCT UniProtKB/TrEMBL
PROSITE IRF_1 UniProtKB/TrEMBL
  IRF_2 UniProtKB/TrEMBL
SMART IRF UniProtKB/TrEMBL
  IRF-3 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF49879 UniProtKB/TrEMBL
UniProt A0A0D9RU36 ENTREZGENE, UniProtKB/TrEMBL