EDN3 (endothelin 3) - Rat Genome Database

Name: EDN3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: EDN3 (endothelin 3) Chlorocebus sabaeus

Analyze

Symbol:

EDN3

Name:

endothelin 3

RGD ID:

18605675

Description:

ENCODES a protein that exhibits endothelin B receptor binding (inferred); hormone activity (inferred); INVOLVED IN artery smooth muscle contraction (ortholog); cell population proliferation (ortholog); establishment of localization in cell (ortholog); PARTICIPATES IN endothelin signaling pathway; ASSOCIATED WITH Bradycardia (ortholog); congenital central hypoventilation syndrome (ortholog); genetic disease (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

endothelin-3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EDN3 (endothelin 3)	NCBI	Ortholog
Mus musculus (house mouse):	Edn3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Edn3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Edn3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EDN3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EDN3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Edn3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EDN3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Edn3 (endothelin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	4,814,447 - 4,839,950 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	4,814,140 - 4,839,626 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	52,860,201 - 52,885,678 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bradycardia (ISO)

congenital central hypoventilation syndrome (ISO)

genetic disease (ISO)

Hirschsprung's disease (ISO)

hypertension (ISO)

Hypotension (ISO)

Intrinsic Sleep Disorders (ISO)

sensorineural hearing loss (ISO)

Waardenburg syndrome (ISO)

Waardenburg Syndrome Type 4 (ISO)

Waardenburg syndrome type 4B (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

artery smooth muscle contraction (ISO)

axon extension (IEA)

axon guidance (IEA)

cell population proliferation (IEA,ISO)

cell surface receptor signaling pathway (IEA)

establishment of localization in cell (IEA,ISO)

intracellular calcium ion homeostasis (IEA,ISO)

intracellular magnesium ion homeostasis (IEA,ISO)

melanocyte differentiation (IEA,ISO)

negative regulation of hormone secretion (ISO)

neural crest cell migration (IEA,ISO)

neuron differentiation (IEA,ISO)

neuron projection development (IEA)

neutrophil chemotaxis (IEA)

peptide hormone secretion (IEA)

positive regulation of cell differentiation (IEA,ISO)

positive regulation of cell population proliferation (IEA,ISO)

positive regulation of heart rate (IEA)

positive regulation of hormone secretion (IEA)

positive regulation of leukocyte chemotaxis (IEA)

positive regulation of mitotic nuclear division (IEA)

positive regulation of potassium ion transmembrane transport (IEA,ISO)

potassium ion transmembrane transport (IEA,ISO)

regulation of cell migration (IEA,ISO)

regulation of developmental pigmentation (IEA,ISO)

regulation of gene expression (IEA,ISO)

regulation of neurotransmitter secretion (ISO)

regulation of systemic arterial blood pressure by endothelin (IEA)

regulation of vasoconstriction (IEA)

vasoconstriction (IEA)

vein smooth muscle contraction (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IEA)

Molecular Function

endothelin B receptor binding (IEA)

hormone activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

endothelin signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

EDN3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	4,814,447 - 4,839,950 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	4,814,140 - 4,839,626 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	52,860,201 - 52,885,678 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

EDN3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	59,300,611 - 59,325,992 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	59,300,443 - 59,325,992 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	57,875,666 - 57,901,047 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	57,308,894 - 57,334,442 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	57,308,893 - 57,334,441	NCBI
Celera	20	54,616,141 - 54,641,690 (+)	NCBI		Celera
Cytogenetic Map	20	q13.32	NCBI
HuRef	20	54,662,632 - 54,688,190 (+)	NCBI		HuRef
CHM1_1	20	57,776,830 - 57,802,379 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	61,083,933 - 61,109,315 (+)	NCBI		T2T-CHM13v2.0

Edn3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	174,602,412 - 174,625,835 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	174,602,412 - 174,625,835 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	174,760,619 - 174,784,042 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	174,760,619 - 174,784,042 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	174,586,274 - 174,609,543 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	174,403,712 - 174,426,981 (+)	NCBI		MGSCv36	mm8
Celera	2	180,720,524 - 180,743,869 (+)	NCBI		Celera
Cytogenetic Map	2	H4	NCBI
cM Map	2	98.1	NCBI

Edn3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	183,980,458 - 184,004,958 (+)	NCBI		GRCr8
mRatBN7.2	3	163,562,307 - 163,586,636 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	163,562,520 - 163,585,093 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	167,361,313 - 167,383,973 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	175,856,634 - 175,879,291 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	173,602,123 - 173,624,707 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	172,856,730 - 172,879,276 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	172,856,733 - 172,880,450 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	178,903,017 - 178,925,563 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	166,491,368 - 166,514,051 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	162,730,251 - 162,752,801 (+)	NCBI		Celera
Cytogenetic Map	3	q43	NCBI

Edn3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	215,859 - 237,760 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955445	215,910 - 238,153 (-)	NCBI	ChiLan1.0	ChiLan1.0

EDN3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	65,065,183 - 65,090,932 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	65,058,300 - 65,084,054 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	55,652,770 - 55,678,486 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	57,012,926 - 57,038,570 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	57,012,926 - 57,038,570 (+)	Ensembl	panpan1.1		panPan2

EDN3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	44,024,553 - 44,054,727 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	44,033,419 - 44,054,050 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	43,279,240 - 43,297,953 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	44,892,278 - 44,922,442 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	44,901,164 - 44,921,767 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	44,002,694 - 44,021,373 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	44,121,425 - 44,140,136 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	44,781,653 - 44,800,349 (+)	NCBI		UU_Cfam_GSD_1.0

Edn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	181,539,619 - 181,562,016 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936530	1,744,199 - 1,765,027 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936530	1,744,216 - 1,766,602 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EDN3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	59,425,495 - 59,448,362 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	59,418,667 - 59,448,382 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	66,846,562 - 66,867,781 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Edn3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624741	25,658,726 - 25,680,763 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium
Low	19	13	59
Below cutoff	17	6	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008012555	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008012563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000013705 ⟹ ENSCSAP00000011695

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	2	4,814,140 - 4,839,626 (-)	Ensembl

RefSeq Acc Id:

XM_008012555 ⟹ XP_008010746

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	2	4,814,447 - 4,839,950 (-)	NCBI
Vero_WHO_p1.0	NW_023666050	52,860,201 - 52,885,678 (-)	NCBI

Sequence:

show sequence

GCGCCACGCCACGCCGCCCCCGCCCCTCGCTGTCCTGGGTGCGCCTCGGGCCGCTGCGCTCCTG
GCCAGCTCCCCCCAGCGCCTGGGAGGCGACCCCCAGTGCGCCCGGGTTCAAAGGCCCCGCGAGG
CAGCTCCAGCCCCTCTGGGGGGCGGGGAGGCGACGGGGGTGGTGCAGAAACCAGAAAAGCCCAA
GCCACAGCCGGCCAGCTCCGCACAGGGATGGGCAGCGCACTCTGAAAGTTTATGACCGCCGCAG
CCAACTCCTGGCTGGAGCTGGAGACACTGAGAGCGATCGGCCGGCCTCGAACCCCCACAGCTGG
AGGGCGAGGCCAGCTGTACCCGGCCCCAGTGCCCTTTCGCGGCCACAGGCGGCCGTCCTCCTGG
TCCTGTGCTCCGGCGCCTGATCTGGGTTCATGGAGCCGGGGCTGTGGCTCCTTTTCGGGCTCAC
AGTGACCTCCGCCGCAGGATTGGTGCCTTGCTCCCAGTCTGGGGATGCTGGCAGGCGCGGCGTG
TCCCAGGTCCCCACGGCAGCCAGATCTGAGGGCGACTGTGAAGAGACTGTGGCTGGCCCTGGTG
AGGGGACTGTGGCCCCGACAGCATTGCAGGGTCCAAGCCCTGGAAGTCCTGGGCAGGAGCAGGT
GGCGGAGGGGGCCCCTGAGCACCACCGATCCAGGCGCTGCACGTGCTTCACCTACAAGGACAAG
GAGTGTGTCTACTATTGCCACCTGGACATCATTTGGATCAACACTCCCGAACAGACCGTGCCCT
ATGGACTGTCCAACTACAGAGGAAGCTTCCGGGGCAAGAGGTCTGCGGGGCTGCTTCCAGGGAA
CCTGCAGCTTTCGCATCGACCACACTCGCGCTGCGCTTGTGTGGGGAGATATGACAAGGCCTGC
CTGCACTTTTGCACCCAAACTCTGGACGTCAGCAGTAATTCAAGGACGGCAGAAAAAACAGACA
AAGAAGAGGAAGGGAAGGTTGAAGTCAAGGACAGACAAAGCAAGCAGGCTTTAGACCTCCACCA
TCCAAAGCTCGTGCCCGGCAGTGGACTCGCCCTTGCTCCATCTACCTGCCCCCGCTGCCTCTTT
GAAGAAGGAGCCCCTTAGGAGGACAGGCCTGAAGCATCCTGGTCTTGGGAGGCTTCTGTCATTG
CTCACACACAGTTCAGATTTCCACCTCTTTACGGACAAGGAGTGAATTTGCCTGGGGCAGAATA
CCCACCCAAAGAGTCCCCACTTAACAATACCCCCCACTGCAAGAATGCCCAAATCCAAATGACC
CCAGTTTTCCTAATGGGTAAAATGATCCCAGATGTGCCCCAGAGCATGACGCCTGCAGCTCCGG
TTTCATGCAGGAAATTGTTTTTGGAGAGGTTTGGCAAGTTGGAAAGCCACTTACTGGCTTTTGA
TATGACTTCTCTTGGAGAATAAGTGGACTCCAAGCTAACTCTTTGCAAATGTAAACACGTGTCC
ATCTTGAAATAAATGCAAAATGCCCGTGCAACAGAAGCATGTGACTTTCATATCCTTGCCTAGA
ATAGGCTGCATGGTGTATGTCAGTGAGGGCCACAAGGCATCAGCTTTAGACACAGATCATAGCT
CTACAGGAGTTTATGAATTTGAAGCTTATGGGATTTTGTCAGAGAAATTTTCAGCTGTGCTTGA
TACCCACCAAAAGAATGTATCTCAAAAGAATGAAGGAAGAAGAAAAAAGGATCCTTGATGTTTG
TGACAAGAAAAGGAGAAAGTATCTGCAATACGGAGCTTGTTCCTATTCAGTGACTGACCCTCTG
TATTCTGTATAGACACCAGGATGCTACACAATGGAGTTCCCAGGCCTTGTTTGCAGGAAGCCGA
CTATAAAGACAGCCCCAGCTCAAGGCTATTAGGTTGAATATTTGCTTTCATAAACAAATGTGGA
TCTTTGGGGAATGGCTTCAAAATAAGTCATGAACACAAATTCTTTGTAAATTATGTAAATTCCT
GTTTATCTATATAAATTGGCAACAACTGGGAATTGTACCGCCTGACAGTTCAAAATCTCTTTCA
GCTGCTCTCTTCCCGCCGAGCTGAGCTTACCATGAGTGTGGAAATGTGGCCCTGCCATGTAAAG
TCGCCTGTGCAGGGGAGAGGCCACCACCTCCCCACCCGGCCGCAGAGAGATAAGAAATGGCATT
TGAGTTGGGTGTCCAGGGCCCTGTGTGGAGATATTTAAGATGGTGTATGACAGAGCATTGGCCT
TGACCAAATGTTAAATTCTCTATGCGTATTTCCTAAGTTATTACAGGTATAAAAGTGATGACCT
ATCTTGAGGAAATGAAAGTGGCTGATTTGCTGGTAGAATTTTGTACAGTTTAGAGAAGCGATTA
TTTATTGTGAAACTATTCTCTACTCCAACTCTTTTATGTGGATCTGTTCCAAGTAGTCACTGTA
TATATGAATAGATAGGTAGGTATTTTAAATTGCATTCTGAATCCAAACTCATATTCCTTAGAGC
TTGAATTACATTTTTAAAATGCATATGTGCTGTTTGGCACCATGGCAAGATGGTATCAGCGAGA
AACTCATTCATTGCTCAAACACTCAGAAAGTACTGCCAAAAGCCTAATAAAAAATCTAAAGTTT
GCTCTGA

hide sequence

RefSeq Acc Id:

XM_008012563 ⟹ XP_008010754

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	2	4,814,447 - 4,839,948 (-)	NCBI
Vero_WHO_p1.0	NW_023666050	52,860,201 - 52,885,678 (-)	NCBI

Sequence:

show sequence

GCCACGCCACGCCGCCCCCGCCCCTCGCTGTCCTGGGTGCGCCTCGGGCCGCTGCGCTCCTGGC
CAGCTCCCCCCAGCGCCTGGGAGGCGACCCCCAGTGCGCCCGGGTTCAAAGGCCCCGCGAGGCA
GCTCCAGCCCCTCTGGGGGGCGGGGAGGCGACGGGGGTGGTGCAGAAACCAGAAAAGCCCAAGC
CACAGCCGGCCAGCTCCGCACAGGGATGGGCAGCGCACTCTGAAAGTTTATGACCGCCGCAGCC
AACTCCTGGCTGGAGCTGGAGACACTGAGAGCGATCGGCCGGCCTCGAACCCCCACAGCTGGAG
GGCGAGGCCAGCTGTACCCGGCCCCAGTGCCCTTTCGCGGCCACAGGCGGCCGTCCTCCTGGTC
CTGTGCTCCGGCGCCTGATCTGGGTTCATGGAGCCGGGGCTGTGGCTCCTTTTCGGGCTCACAG
TGACCTCCGCCGCAGGATTGGTGCCTTGCTCCCAGTCTGGGGATGCTGGCAGGCGCGGCGTGTC
CCAGGTCCCCACGGCAGCCAGATCTGAGGGCGACTGTGAAGAGACTGTGGCTGGCCCTGGTGAG
GGGACTGTGGCCCCGACAGCATTGCAGGGTCCAAGCCCTGGAAGTCCTGGGCAGGAGCAGGTGG
CGGAGGGGGCCCCTGAGCACCACCGATCCAGGCGCTGCACGTGCTTCACCTACAAGGACAAGGA
GTGTGTCTACTATTGCCACCTGGACATCATTTGGATCAACACTCCCGAACAGACCGTGCCCTAT
GGACTGTCCAACTACAGAGGAAGCTTCCGGGGCAAGAGGTCTGCGGGGCTGCTTCCAGGGAACC
TGCAGCTTTCGCATCGACCACACTCGCGCTGCGCTTGTGTGGGGAGATATGACAAGGCCTGCCT
GCACTTTTGCACCCAAACTCTGGACGTCAGCAGTAATTCAAGGACGGCAGAAAAAACAGACAAA
GAAGAGGAAGGGAAGGTGAGAGGTGCCAACAGAGGCCTGTGTCAAAGGAGGTTGAAGTCAAGGA
CAGACAAAGCAAGCAGGCTTTAGACCTCCACCATCCAAAGCTCGTGCCCGGCAGTGGACTCGCC
CTTGCTCCATCTACCTGCCCCCGCTGCCTCTTTGAAGAAGGAGCCCCTTAGGAGGACAGGCCTG
AAGCATCCTGGTCTTGGGAGGCTTCTGTCATTGCTCACACACAGTTCAGATTTCCACCTCTTTA
CGGACAAGGAGTGAATTTGCCTGGGGCAGAATACCCACCCAAAGAGTCCCCACTTAACAATACC
CCCCACTGCAAGAATGCCCAAATCCAAATGACCCCAGTTTTCCTAATGGGTAAAATGATCCCAG
ATGTGCCCCAGAGCATGACGCCTGCAGCTCCGGTTTCATGCAGGAAATTGTTTTTGGAGAGGTT
TGGCAAGTTGGAAAGCCACTTACTGGCTTTTGATATGACTTCTCTTGGAGAATAAGTGGACTCC
AAGCTAACTCTTTGCAAATGTAAACACGTGTCCATCTTGAAATAAATGCAAAATGCCCGTGCAA
CAGAAGCATGTGACTTTCATATCCTTGCCTAGAATAGGCTGCATGGTGTATGTCAGTGAGGGCC
ACAAGGCATCAGCTTTAGACACAGATCATAGCTCTACAGGAGTTTATGAATTTGAAGCTTATGG
GATTTTGTCAGAGAAATTTTCAGCTGTGCTTGATACCCACCAAAAGAATGTATCTCAAAAGAAT
GAAGGAAGAAGAAAAAAGGATCCTTGATGTTTGTGACAAGAAAAGGAGAAAGTATCTGCAATAC
GGAGCTTGTTCCTATTCAGTGACTGACCCTCTGTATTCTGTATAGACACCAGGATGCTACACAA
TGGAGTTCCCAGGCCTTGTTTGCAGGAAGCCGACTATAAAGACAGCCCCAGCTCAAGGCTATTA
GGTTGAATATTTGCTTTCATAAACAAATGTGGATCTTTGGGGAATGGCTTCAAAATAAGTCATG
AACACAAATTCTTTGTAAATTATGTAAATTCCTGTTTATCTATATAAATTGGCAACAACTGGGA
ATTGTACCGCCTGACAGTTCAAAATCTCTTTCAGCTGCTCTCTTCCCGCCGAGCTGAGCTTACC
ATGAGTGTGGAAATGTGGCCCTGCCATGTAAAGTCGCCTGTGCAGGGGAGAGGCCACCACCTCC
CCACCCGGCCGCAGAGAGATAAGAAATGGCATTTGAGTTGGGTGTCCAGGGCCCTGTGTGGAGA
TATTTAAGATGGTGTATGACAGAGCATTGGCCTTGACCAAATGTTAAATTCTCTATGCGTATTT
CCTAAGTTATTACAGGTATAAAAGTGATGACCTATCTTGAGGAAATGAAAGTGGCTGATTTGCT
GGTAGAATTTTGTACAGTTTAGAGAAGCGATTATTTATTGTGAAACTATTCTCTACTCCAACTC
TTTTATGTGGATCTGTTCCAAGTAGTCACTGTATATATGAATAGATAGGTAGGTATTTTAAATT
GCATTCTGAATCCAAACTCATATTCCTTAGAGCTTGAATTACATTTTTAAAATGCATATGTGCT
GTTTGGCACCATGGCAAGATGGTATCAGCGAGAAACTCATTCATTGCTCAAACACTCAGAAAGT
ACTGCCAAAAGCCTAATAAAAAATCTAAAGTTTGCTCTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008010746	(Get FASTA)	NCBI Sequence Viewer
	XP_008010754	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000011695.1

RefSeq Acc Id:	XP_008010746 ⟸ XM_008012555
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_008010754 ⟸ XM_008012563
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSCSAP00000011695 ⟸ ENSCSAT00000013705

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000015608	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000013705.1	UniProtKB/TrEMBL
InterPro	Endothelin	UniProtKB/TrEMBL
	Endothelin_toxin_CS	UniProtKB/TrEMBL
	Endothln-like_toxin	UniProtKB/TrEMBL
KEGG Report	csab:103243376	UniProtKB/TrEMBL
NCBI Gene	EDN3	ENTREZGENE
PANTHER	ENDOTHELIN-3	UniProtKB/TrEMBL
	PTHR13874	UniProtKB/TrEMBL
Pfam	Endothelin	UniProtKB/TrEMBL
PRINTS	ENDOTHELIN	UniProtKB/TrEMBL
PROSITE	ENDOTHELIN	UniProtKB/TrEMBL
SMART	END	UniProtKB/TrEMBL
UniProt	A0A0D9RSV6_CHLSB	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)