RAMP3 (receptor activity modifying protein 3)

Gene: RAMP3 (receptor activity modifying protein 3) Chlorocebus sabaeus

Analyze

Symbol:

RAMP3

Name:

receptor activity modifying protein 3

RGD ID:

18591499

Description:

ENCODES a protein that exhibits adrenomedullin receptor activity (ortholog); amylin receptor activity (ortholog); coreceptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adrenomedullin receptor signaling pathway (ortholog); amylin receptor signaling pathway (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); genetic disease (ortholog); Lymphatic Metastasis (ortholog); FOUND IN adrenomedullin receptor complex (ortholog); amylin receptor complex 3 (ortholog); cell surface (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

receptor activity-modifying protein 3

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	13,494,981 - 13,521,141 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666062	9,009,778 - 9,035,756 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

colorectal cancer (ISO)

genetic disease (ISO)

Lymphatic Metastasis (ISO)

pleomorphic xanthoastrocytoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating G protein-coupled receptor signaling pathway (ISO)

adrenomedullin receptor signaling pathway (ISO)

amylin receptor signaling pathway (ISO)

calcium ion transport (ISO)

cellular response to estradiol stimulus (ISO)

G protein-coupled receptor signaling pathway (ISO)

G protein-coupled receptor signaling pathway involved in heart process (ISO)

positive regulation of calcium-mediated signaling (ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

positive regulation of gene expression (ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

positive regulation of protein kinase A signaling (ISO)

positive regulation of protein localization to plasma membrane (ISO)

positive regulation of receptor recycling (ISO)

protein localization to plasma membrane (ISO)

protein transport (ISO)

receptor internalization (ISO)

response to amyloid-beta (ISO)

Cellular Component

adrenomedullin receptor complex (ISO)

amylin receptor complex 3 (ISO)

cell surface (ISO)

lysosome (ISO)

plasma membrane (ISO)

receptor complex (ISO)

Molecular Function

adrenomedullin receptor activity (ISO)

amylin receptor activity (ISO)

coreceptor activity (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

RAMP3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	13,494,981 - 13,521,141 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666062	9,009,778 - 9,035,756 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

RAMP3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	45,157,791 - 45,184,250 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	45,157,791 - 45,186,302 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	45,197,390 - 45,223,849 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	45,163,892 - 45,190,374 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	44,970,638 - 44,997,087	NCBI
Celera	7	45,296,201 - 45,322,683 (+)	NCBI		Celera
Cytogenetic Map	7	p13	NCBI
HuRef	7	45,081,154 - 45,107,455 (+)	NCBI		HuRef
CHM1_1	7	45,201,027 - 45,227,508 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	45,318,568 - 45,345,028 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	45,236,530 - 45,263,012 (+)	NCBI

Ramp3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	6,608,507 - 6,627,478 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	6,608,521 - 6,627,475 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	6,658,506 - 6,677,478 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	6,658,521 - 6,677,475 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	6,558,536 - 6,577,478 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	6,558,536 - 6,577,478 (+)	NCBI		MGSCv36	mm8
Celera	11	18,979,836 - 18,982,575 (-)	NCBI		Celera
Cytogenetic Map	11	A1	NCBI
cM Map	11	4.61	NCBI

Ramp3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	85,741,314 - 85,758,813 (+)	NCBI		GRCr8
mRatBN7.2	14	81,527,404 - 81,544,905 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	81,527,385 - 81,544,902 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	85,928,688 - 85,946,185 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	87,168,498 - 87,186,001 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	83,618,093 - 83,635,590 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	86,922,223 - 86,939,722 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	86,922,223 - 86,939,719 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	80,555,482 - 80,572,981 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	87,417,290 - 87,434,789 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	87,436,434 - 87,453,933 (+)	NCBI
Celera	14	80,409,008 - 80,426,508 (+)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

Ramp3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955456	7,159,845 - 7,168,792 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955456	7,159,845 - 7,168,718 (-)	NCBI	ChiLan1.0	ChiLan1.0

RAMP3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	50,070,783 - 50,097,555 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	98,395,524 - 98,422,292 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	45,871,687 - 45,898,159 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	45,937,607 - 45,964,088 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	45,937,607 - 45,966,041 (+)	Ensembl	panpan1.1		panPan2

RAMP3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	16	2,664,601 - 2,679,402 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	14,181,470 - 14,196,274 (-)	NCBI		ROS_Cfam_1.0
UNSW_CanFamBas_1.0	16	13,814,391 - 13,829,193 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	13,793,847 - 13,808,648 (-)	NCBI		UU_Cfam_GSD_1.0

Ramp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	100,765,846 - 100,789,731 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936478	19,977,539 - 20,004,838 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936478	19,977,618 - 20,001,366 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAMP3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	50,319,797 - 50,366,739 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	50,319,795 - 50,366,757 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	55,155,083 - 55,174,055 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Ramp3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	7,241,296 - 7,249,410 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624740	7,240,841 - 7,249,313 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007981392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007981393	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_007981393 ⟹ XP_007979584

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	21	13,494,981 - 13,521,135 (-)	NCBI
Vero_WHO_p1.0	NW_023666062	9,009,778 - 9,035,756 (+)	NCBI

Sequence:

show sequence

CCAACCCCATCCGGGCGTCCCGGTTGCACCCCCAGCCGGACCAAGCGTGACCCAGCCGCGGCCG
GCCAGCCATGGAGACTGGAGCGCGGCGGCGCCCGCAACTTCTCCCGCTGCTGCTGCTGCTCTGC
GGTGGGTGTCCCAGAGCGGGCGGCTGCAACGAGACAGGCCTGTTGGAGAGGCTGCCCCTGTGTG
GGAAGGCTTTCGCAGACATGATGGGCAAGCTGGACGTCTGGAAGTGGTGCAACCTGTCCGAGTT
CATCGTGTACTATGAGAGTTTCACCAACTGCACCGAGATGGAGGCCAACATCGTGGGCTGCTAC
TGGCCCAACCCCCTGGCCCAGGGCTTCATCACCGGCATCCACAGGCAGTTCTTCTCCAACTGCA
CCATGGACAAGGTCCACTTGGAGGACCCCCCAGACGAGGTTCTTATCCCGCTGATCATTATCCC
CGTCGTTCTGACTGTCGCCATGGCTGGCCTGGTGGTGTGGCGCAGCAAGCGCACCGACACGCTG
CTGTGAGGGTCTGGGTGAGATGGAGTGGGTCACACCTGGCAAGCTGGAAGAAAGTTCCCTGGGG
ATGGGAGGACGGATGGGTACTACCAATCTCCAGCTACTGTGGCCACACCCTACCTGGTCATGGG
CAGACCCCTCCCTTCCTGGGCTGACCTGCTCCCTCGAGGCCAGCCTGCTCCCTGGCCGAGGCTC
AGGCTATCCGCCCAAGCTCTTTGCTCATTCTAGGGCCAGTGGAGGAAAATGTGATAAGGCCAGA
GCTTATGTGCTGGGCGCAGAAATCACCTGCTGTGTCCTGTGCTCCGCAGGCTGGGCCGGAGCCT
CTGCCCGGAGGTTTCTATGCCATTTCTTAGCACAGAATCCAGCCTAGCCTTAGCTGCAGTCTAG
GTCCTGCTTAGACTAGAACTCCTGGCCTGACCCCATCTCTAGTTCCTGCCTTGGCTCCTGCCCC
AGCCCCGGCCCCTGCCTACATCCAGACAGAAAGACAGGCAGGGGCTCTTGGAAGACGTTCCATG
CTGTAGAAGATGTTCTGTGTTGTGAACTCTGAGCCCACCTGGTAGGAAGACAGCTGGAAAGGCT
GGGAGGAGAAGGGAGGGGCTGGGGGGTTCCCAGGAACCACGCGTGGCCTGCAGAGTCCATTCCA
TCATGATGCTGTGCCCACTATGGGCTGTGTCCGTGACCAGAGGCTGGAGTGGGAGTGTGTCAGA
GCCCCTCACCAGGGCTTGCTGTGTGGATGGGGCCTGGGCCTCCTTCCTACTGGGGCTCCTCTGT
GGGTGAGGGGCCCTCTGGAATGGCATACCATGAGCTTGTGGCCTCTATCTGCTACCATCTGCAT
TTTATCTGAGTAAAGTTACCTTACTTCTGGAA

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Protein Sequences


Protein RefSeqs	XP_007979584	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_007979584 ⟸ XM_007981393

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	RAMP3	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar