COL18A1 (collagen type XVIII alpha 1 chain)

Gene: COL18A1 (collagen type XVIII alpha 1 chain) Chlorocebus sabaeus

Analyze

Symbol:

COL18A1

Name:

collagen type XVIII alpha 1 chain

RGD ID:

18590719

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); blood vessel endothelial cell migration (ortholog); endothelial cell apoptotic process (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH angiosarcoma (ortholog); angle-closure glaucoma (ortholog); autistic disorder (ortholog); FOUND IN basement membrane (ortholog); extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

collagen alpha-1(XVIII) chain

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	89,129,674 - 89,186,490 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666054	17,263,431 - 17,447,521 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

angiosarcoma (ISO)

angle-closure glaucoma (ISO)

autistic disorder (ISO)

Axenfeld-Rieger syndrome type 3 (ISO)

calcinosis (ISO)

cataract (ISO)

cataract 9 multiple types (ISO)

Colonic Neoplasms (ISO)

COVID-19 (ISO)

developmental and epileptic encephalopathy 30 (ISO)

epilepsy (ISO)

Experimental Mammary Neoplasms (ISO)

Fibrosis (ISO)

fundus dystrophy (ISO)

gastric ulcer (ISO)

genetic disease (ISO)

heart valve disease (ISO)

hepatocellular carcinoma (ISO)

Hereditary Eye Diseases (ISO)

homocystinuria (ISO)

intellectual disability (ISO)

Knobloch Syndrome (ISO)

Knobloch Syndrome Type I (ISO)

macular degeneration (ISO)

neurodegenerative disease (ISO)

Neurodevelopmental Disorders (ISO)

pigment dispersion syndrome (ISO)

primary angle-closure glaucoma (ISO)

primary ciliary dyskinesia (ISO)

progressive myoclonus epilepsy (ISO)

retinitis pigmentosa (ISO)

ulcerative colitis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IEA,ISO)

blood vessel endothelial cell migration (ISO)

endothelial cell apoptotic process (ISO)

endothelial cell morphogenesis (IEA,ISO)

extracellular matrix organization (IEA,ISO)

positive regulation of blood vessel endothelial cell migration (ISO)

positive regulation of endothelial cell apoptotic process (ISO)

positive regulation of vascular endothelial cell proliferation (ISO)

response to hydrostatic pressure (ISO)

response to xenobiotic stimulus (ISO)

vascular endothelial cell proliferation (ISO)

Cellular Component

basement membrane (ISO)

collagen trimer (IEA)

collagen-containing extracellular matrix (IEA)

endoplasmic reticulum lumen (IEA)

extracellular space (IEA,ISO)

Molecular Function

extracellular matrix structural constituent conferring tensile strength (IEA)

identical protein binding (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

forkhead class A signaling pathway (ISO)

References

Genomics

Comparative Map Data

COL18A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	89,129,674 - 89,186,490 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666054	17,263,431 - 17,447,521 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

COL18A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	45,405,165 - 45,513,720 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	21	45,405,165 - 45,513,720 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	21	46,825,080 - 46,933,634 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	45,649,525 - 45,758,062 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	21	45,649,524 - 45,758,061	NCBI
Celera	21	31,935,820 - 32,044,503 (+)	NCBI		Celera
Cytogenetic Map	21	q22.3	NCBI
HuRef	21	32,201,756 - 32,310,095 (+)	NCBI		HuRef
CHM1_1	21	46,385,935 - 46,494,464 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	21	43,770,922 - 43,881,831 (+)	NCBI		T2T-CHM13v2.0

Col18a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	76,888,013 - 77,002,351 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	76,888,012 - 77,002,382 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	77,052,178 - 77,166,530 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	77,052,178 - 77,166,548 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	76,514,924 - 76,629,275 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	76,495,895 - 76,610,217 (-)	NCBI		MGSCv36	mm8
Celera	10	78,096,179 - 78,210,613 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Col18a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	11,473,645 - 11,582,111 (+)	NCBI		GRCr8
mRatBN7.2	20	11,474,104 - 11,582,593 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	11,474,104 - 11,582,593 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	12,170,630 - 12,278,993 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	11,531,618 - 11,639,977 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	12,003,376 - 12,111,737 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	12,225,202 - 12,332,858 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	12,225,202 - 12,332,858 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	14,388,743 - 14,495,241 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	11,920,816 - 11,982,468 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	11,979,239 - 11,981,856 (+)	NCBI
Celera	20	12,974,396 - 13,081,322 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

Col18a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	42,091,211 - 42,131,343 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	42,091,211 - 42,131,343 (+)	NCBI	ChiLan1.0	ChiLan1.0

COL18A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	22	41,474,960 - 41,590,499 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	21	36,343,211 - 36,459,037 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	21	31,720,358 - 31,834,470 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	21	45,046,791 - 45,106,225 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

COL18A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	38,915,872 - 38,957,484 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	38,143,980 - 38,184,998 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	38,552,331 - 38,593,457 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	38,519,589 - 38,593,442 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	38,415,729 - 38,457,167 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	38,375,432 - 38,416,875 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	38,893,993 - 38,935,752 (+)	NCBI		UU_Cfam_GSD_1.0

Col18a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	38,186,994 - 38,282,739 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936778	847,473 - 943,038 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

COL18A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	207,940,948 - 207,982,938 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	207,907,835 - 207,984,082 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	218,076,734 - 218,090,016 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Col18a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624745	30,754,820 - 30,791,426 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624745	30,754,654 - 30,792,352 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007971937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_037985438	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_037985438 ⟹ XP_037841366

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
Vero_WHO_p1.0	NW_023666054	17,263,431 - 17,447,521 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_037841366	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000003730.1

RefSeq Acc Id:	XP_037841366 ⟸ XM_037985438
- UniProtKB:	A0A0D9R541 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000007471	UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000005512.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.200	UniProtKB/TrEMBL
	3.40.1620.70	UniProtKB/TrEMBL
InterPro	Collagen	UniProtKB/TrEMBL
	ConA-like_dom_sf	UniProtKB/TrEMBL
	TSPN-like_N	UniProtKB/TrEMBL
	XV/XVIII_trimerization_dom	UniProtKB/TrEMBL
NCBI Gene	COL18A1	ENTREZGENE
PANTHER	COLLAGEN ALPHA	UniProtKB/TrEMBL
	COLLAGEN ALPHA-1(XVIII) CHAIN	UniProtKB/TrEMBL
Pfam	Collagen	UniProtKB/TrEMBL
	Collagen_trimer	UniProtKB/TrEMBL
SMART	TSPN	UniProtKB/TrEMBL
Superfamily-SCOP	Concanavalin A-like lectins/glucanases	UniProtKB/TrEMBL
UniProt	A0A0D9R541	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)