CORO2B (coronin 2B) - Rat Genome Database

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Gene: CORO2B (coronin 2B) Chlorocebus sabaeus
Analyze
Symbol: CORO2B
Name: coronin 2B
RGD ID: 18558064
Description: ENCODES a protein that exhibits talin binding (ortholog); vinculin binding (ortholog); INVOLVED IN focal adhesion assembly (ortholog); negative regulation of cell-substrate adhesion (ortholog); negative regulation of establishment of protein localization (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); COVID-19 (ortholog); FOUND IN focal adhesion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: coronin-2B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12614,746,497 - 14,909,483 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2614,746,379 - 14,895,951 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048126,574,113 - 126,724,538 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CORO2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12614,746,497 - 14,909,483 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2614,746,379 - 14,895,951 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048126,574,113 - 126,724,538 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CORO2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381568,518,373 - 68,727,806 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1568,578,993 - 68,727,806 (+)EnsemblGRCh38hg38GRCh38
GRCh371568,810,712 - 69,020,145 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361566,658,627 - 66,807,199 (+)NCBINCBI36Build 36hg18NCBI36
Build 341566,658,645 - 66,807,193NCBI
Celera1545,798,327 - 45,909,300 (+)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1545,705,372 - 45,853,698 (+)NCBIHuRef
CHM1_11568,989,282 - 69,138,119 (+)NCBICHM1_1
T2T-CHM13v2.01566,341,263 - 66,550,386 (+)NCBIT2T-CHM13v2.0
Coro2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39962,326,770 - 62,444,326 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl962,326,774 - 62,444,326 (-)EnsemblGRCm39 Ensembl
GRCm38962,419,490 - 62,537,044 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl962,419,492 - 62,537,044 (-)EnsemblGRCm38mm10GRCm38
MGSCv37962,267,299 - 62,384,851 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36962,217,503 - 62,335,050 (-)NCBIMGSCv36mm8
Celera959,643,037 - 59,752,273 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map933.71NCBI
Coro2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8871,802,329 - 71,912,739 (-)NCBIGRCr8
mRatBN7.2862,906,861 - 63,017,295 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl862,906,867 - 63,017,302 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0867,374,617 - 67,492,490 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl867,376,294 - 67,492,037 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0867,107,332 - 67,223,553 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4866,573,135 - 66,651,600 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera862,323,812 - 62,434,442 (-)NCBICelera
Cytogenetic Map8q24NCBI
Coro2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554507,521,188 - 7,573,575 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554507,522,447 - 7,573,043 (-)NCBIChiLan1.0ChiLan1.0
CORO2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21657,780,429 - 57,989,761 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11562,014,725 - 62,163,270 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01547,536,641 - 47,685,357 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11566,370,760 - 66,452,545 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1566,370,374 - 66,452,545 (+)Ensemblpanpan1.1panPan2
CORO2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13032,574,068 - 32,701,494 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3032,627,373 - 32,702,757 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3032,502,452 - 32,635,221 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03032,765,185 - 32,898,489 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3032,765,171 - 32,899,752 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13032,691,878 - 32,824,917 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03032,755,902 - 32,889,573 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03033,000,020 - 33,133,491 (+)NCBIUU_Cfam_GSD_1.0
Coro2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640110,585,976 - 110,704,075 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647128,481,630 - 28,552,160 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647128,481,615 - 28,552,143 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CORO2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1166,465,953 - 166,608,363 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11166,465,870 - 166,608,840 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21184,299,326 - 184,442,301 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Coro2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247814,507,601 - 4,601,359 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247814,507,916 - 4,617,274 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 40
Low 36 13 20
Below cutoff 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000011613   ⟹   ENSCSAP00000009680
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2614,746,379 - 14,895,951 (-)Ensembl
RefSeq Acc Id: XM_008016105   ⟹   XP_008014296
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12614,746,497 - 14,897,467 (-)NCBI
Vero_WHO_p1.0NW_023666048126,574,113 - 126,724,538 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008014296 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000009680
  ENSCSAP00000009680.1
Reference Protein Sequences
RefSeq Acc Id: XP_008014296   ⟸   XM_008016105
- UniProtKB: A0A0D9RM41 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000009680   ⟸   ENSCSAT00000011613


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013518 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011613.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Coronin UniProtKB/TrEMBL
  DUF1899 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene CORO2B ENTREZGENE
PANTHER PTHR10856 UniProtKB/TrEMBL
  PTHR10856:SF17 UniProtKB/TrEMBL
Pfam DUF1899 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
  WD40_4 UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART DUF1899 UniProtKB/TrEMBL
  DUF1900 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0D9RM41 ENTREZGENE, UniProtKB/TrEMBL