RP1 (RP1 axonemal microtubule associated) - Rat Genome Database

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Gene: RP1 (RP1 axonemal microtubule associated) Chlorocebus sabaeus
Analyze
Symbol: RP1
Name: RP1 axonemal microtubule associated
RGD ID: 18547806
Description: ENCODES a protein that exhibits microtubule binding (ortholog); INVOLVED IN cellular response to light stimulus (ortholog); photoreceptor cell maintenance (ortholog); photoreceptor cell outer segment organization (ortholog); PARTICIPATES IN retinitis pigmentosa pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN ciliary tip (ortholog); microtubule associated complex (ortholog); photoreceptor cell cilium (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lipoxygenase homology domain-containing protein 1-like; LOC103236809; LOC103236812; oxygen-regulated protein 1; retinitis pigmentosa 1 (autosomal dominant); uncharacterized LOC103236809; uncharacterized protein LOC103236809
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1850,743,699 - 50,837,089 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl850,627,957 - 50,685,911 (+)NCBIChlSab1.1ChlSab1.1 EnsemblchlSab2
ChlSab1.1 Ensembl850,627,957 - 50,685,911 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603990,878,192 - 91,240,016 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1850,743,699 - 50,837,089 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl850,627,957 - 50,685,911 (+)NCBIChlSab1.1ChlSab1.1 EnsemblchlSab2
ChlSab1.1 Ensembl850,627,957 - 50,685,911 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603990,878,192 - 91,240,016 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38854,559,185 - 54,871,234 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl854,509,422 - 54,871,720 (+)EnsemblGRCh38hg38GRCh38
GRCh37855,471,745 - 55,783,794 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36855,691,180 - 55,705,947 (+)NCBINCBI36Build 36hg18NCBI36
Build 34855,691,179 - 55,705,947NCBI
Celera851,519,220 - 51,533,987 (+)NCBICelera
Cytogenetic Map8q11.23-q12.1NCBI
HuRef850,996,864 - 51,011,630 (+)NCBIHuRef
CHM1_1855,580,233 - 55,594,998 (+)NCBICHM1_1
T2T-CHM13v2.0854,886,748 - 55,248,781 (+)NCBIT2T-CHM13v2.0
Rp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914,185,896 - 4,479,508 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14,069,780 - 4,479,464 (-)EnsemblGRCm39 Ensembl
GRCm3814,115,673 - 4,409,266 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13,999,557 - 4,409,241 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714,334,224 - 4,350,473 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614,334,224 - 4,350,473 (-)NCBIMGSCv36mm8
Celera14,363,200 - 4,379,450 (-)NCBICelera
Cytogenetic Map1A1NCBI
cM Map11.65NCBI
Rp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8519,918,728 - 20,380,811 (+)NCBIGRCr8
mRatBN7.2515,121,104 - 15,582,363 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl515,121,133 - 15,579,363 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx517,359,324 - 17,375,651 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0518,956,553 - 18,972,879 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0518,693,943 - 18,710,270 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0515,005,028 - 15,060,508 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl515,043,955 - 15,060,508 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0519,789,094 - 19,844,587 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4515,393,101 - 15,401,890 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera514,541,674 - 14,558,002 (+)NCBICelera
Cytogenetic Map5q12NCBI
Rp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545413,781,556 - 14,082,310 (+)NCBIChiLan1.0ChiLan1.0
RP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2770,191,285 - 70,524,500 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1845,916,098 - 46,248,935 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0850,979,412 - 51,311,431 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1848,454,096 - 48,617,283 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl848,419,033 - 48,583,879 (+)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl848,419,033 - 48,583,879 (+)NCBIpanpan1.1panPan2
RP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1296,079,519 - 6,136,009 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl296,079,377 - 6,136,009 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha296,435,871 - 6,446,199 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0296,193,857 - 6,204,194 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl296,147,680 - 6,204,194 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1296,139,004 - 6,149,329 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0296,345,098 - 6,355,440 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0296,523,726 - 6,534,052 (+)NCBIUU_Cfam_GSD_1.0
Rp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530373,123,919 - 73,388,680 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364961,524,123 - 1,583,114 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl476,724,604 - 76,734,610 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1476,724,604 - 76,730,264 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Rp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247351,093,929 - 1,179,265 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247351,129,333 - 1,179,387 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 1 12 40
Below cutoff 35 7 20

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000012745   ⟹   ENSCSAP00000010774
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl850,627,957 - 50,685,911 (+)Ensembl
RefSeq Acc Id: XM_008000661   ⟹   XP_007998852
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603991,177,268 - 91,185,774 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038000495   ⟹   XP_037856423
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603991,177,268 - 91,240,016 (-)NCBI
RefSeq Acc Id: XM_038000496   ⟹   XP_037856424
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603991,177,268 - 91,239,817 (-)NCBI
RefSeq Acc Id: XM_038000497   ⟹   XP_037856425
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603991,177,268 - 91,240,016 (-)NCBI
RefSeq Acc Id: XM_038000498   ⟹   XP_037856426
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603991,177,268 - 91,240,016 (-)NCBI
RefSeq Acc Id: XM_038000499   ⟹   XP_037856427
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603991,177,268 - 91,240,016 (-)NCBI
RefSeq Acc Id: XM_038000500   ⟹   XP_037856428
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603990,878,192 - 91,240,016 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCSAP00000010774   ⟸   ENSCSAT00000012745
RefSeq Acc Id: XP_037856428   ⟸   XM_038000500
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037856425   ⟸   XM_038000497
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RQ85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037856423   ⟸   XM_038000495
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RQ85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037856427   ⟸   XM_038000499
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RQ85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037856426   ⟸   XM_038000498
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RQ85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037856424   ⟸   XM_038000496
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RQ85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007998852   ⟸   XM_008000661
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RQ85 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014645 ENTREZGENE, UniProtKB/TrEMBL
  ENSCSAG00000014654 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012739.1 UniProtKB/TrEMBL
  ENSCSAT00000012745.1 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.50 UniProtKB/TrEMBL
  3.10.20.230 UniProtKB/TrEMBL
  PLAT/LH2 domain UniProtKB/TrEMBL
InterPro Doublecortin_dom UniProtKB/TrEMBL
  Doublecortin_dom_sf UniProtKB/TrEMBL
  IL1/FGF UniProtKB/TrEMBL
  PLAT/LH2_dom UniProtKB/TrEMBL
  PLAT/LH2_dom_sf UniProtKB/TrEMBL
  RP1/RP1L1/DCX UniProtKB/TrEMBL
KEGG Report csab:103236809 UniProtKB/TrEMBL
  csab:103236811 UniProtKB/TrEMBL
NCBI Gene LOC103236809 ENTREZGENE
PANTHER LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  OXYGEN-REGULATED PROTEIN 1 UniProtKB/TrEMBL
  PROTEIN CBG12474 UniProtKB/TrEMBL
  PTHR23005 UniProtKB/TrEMBL
Pfam DCX UniProtKB/TrEMBL
  PLAT UniProtKB/TrEMBL
PROSITE PLAT UniProtKB/TrEMBL
  PS50309 UniProtKB/TrEMBL
SMART DCX UniProtKB/TrEMBL
  LH2 UniProtKB/TrEMBL
Superfamily-SCOP SSF49723 UniProtKB/TrEMBL
  SSF50353 UniProtKB/TrEMBL
  SSF89837 UniProtKB/TrEMBL
UniProt A0A0D9RQ78_CHLSB UniProtKB/TrEMBL
  A0A0D9RQ85 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 RP1  RP1 axonemal microtubule associated  LOC103236809  uncharacterized LOC103236809  Symbol and/or name change 5135510 APPROVED
2020-12-03 LOC103236809  uncharacterized LOC103236809  RP1  RP1 axonemal microtubule associated  Data merged from RGD:18398341 737654 PROVISIONAL
2020-12-03 LOC103236809  uncharacterized LOC103236809  LOC103236812  lipoxygenase homology domain-containing protein 1-like  Data merged from RGD:18458178 737654 PROVISIONAL