PRF1 (perforin 1) - Rat Genome Database

Name: PRF1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: PRF1 (perforin 1) Chlorocebus sabaeus

Analyze

Symbol:

PRF1

Name:

perforin 1

RGD ID:

18523466

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN circadian rhythm (ortholog); defense response to tumor cell (ortholog); granzyme-mediated programmed cell death signaling pathway (ortholog); ASSOCIATED WITH aplastic anemia (ortholog); asthma (ortholog); autistic disorder (ortholog); FOUND IN cytolytic granule (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

perforin-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PRF1 (perforin 1)	NCBI	Ortholog
Mus musculus (house mouse):	Prf1 (perforin 1 (pore forming protein))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Prf1 (perforin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Prf1 (perforin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PRF1 (perforin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PRF1 (perforin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Prf1 (perforin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PRF1 (perforin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Prf1 (perforin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	60,692,544 - 60,698,000 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	60,692,600 - 60,698,465 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	21,417,046 - 21,423,720 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

aplastic anemia (ISO)

asthma (ISO)

autistic disorder (ISO)

Brain Injuries (ISO)

Chediak-Higashi syndrome (ISO)

chronic fatigue syndrome (ISO)

Chronic Hepatitis C (ISO)

colon carcinoma (ISO)

Colonic Neoplasms (ISO)

Crohn's disease (ISO)

Experimental Autoimmune Encephalomyelitis (ISO)

Familial Hemophagocytic Lymphohistiocytoses (ISO)

familial hemophagocytic lymphohistiocytosis 2 (ISO)

Fanconi anemia (ISO)

Flavivirus Infections (ISO)

genetic disease (ISO)

glomerulonephritis (ISO)

hemophagocytic lymphohistiocytosis (ISO)

human immunodeficiency virus infectious disease (ISO)

Human Influenza (ISO)

Macrophage Activation Syndrome (ISO)

malaria (ISO)

membranoproliferative glomerulonephritis (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

milker's nodule (ISO)

multiple sclerosis (ISO)

myocarditis (ISO)

non-Hodgkin lymphoma (ISO)

non-Langerhans-cell histiocytosis (ISO)

systemic lupus erythematosus (ISO)

trypanosomiasis (ISO)

type 1 diabetes mellitus (ISO)

Visceral Heterotaxy 5, Autosomal (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

circadian rhythm (ISO)

defense response to tumor cell (ISO)

defense response to virus (IEA)

granzyme-mediated programmed cell death signaling pathway (ISO)

immune response to tumor cell (ISO)

immunological synapse formation (IEA)

killing of cells of another organism (IEA)

leukocyte mediated cytotoxicity (IEA)

positive regulation of killing of cells of another organism (ISO)

protein homooligomerization (ISO)

protein import (ISO)

protein secretion (ISO)

protein transmembrane transport (ISO)

response to ethanol (ISO)

T cell mediated cytotoxicity (IEA,ISO)

transmembrane transport (IEA)

Cellular Component

cytolytic granule (ISO)

cytoplasmic vesicle (ISO)

cytosol (ISO)

extracellular region (IEA)

extracellular space (ISO)

immunological synapse (ISO)

membrane (ISO)

plasma membrane (ISO)

Molecular Function

calcium ion binding (IEA)

identical protein binding (ISO)

pore-forming activity (IEA)

protein binding (ISO)

wide pore channel activity (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

PRF1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	60,692,544 - 60,698,000 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	60,692,600 - 60,698,465 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	21,417,046 - 21,423,720 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

PRF1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	70,597,348 - 70,602,741 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	70,597,348 - 70,602,759 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	72,357,104 - 72,362,497 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	72,027,110 - 72,032,537 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	72,027,110 - 72,032,520	NCBI
Celera	10	65,638,863 - 65,644,316 (-)	NCBI		Celera
Cytogenetic Map	10	q22.1	NCBI
HuRef	10	66,350,612 - 66,356,064 (-)	NCBI		HuRef
CHM1_1	10	72,639,251 - 72,644,703 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	71,467,050 - 71,472,469 (-)	NCBI		T2T-CHM13v2.0

Prf1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	61,133,530 - 61,140,463 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	61,133,612 - 61,140,459 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	61,297,751 - 61,304,684 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	61,297,833 - 61,304,680 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	60,760,584 - 60,767,011 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	60,693,191 - 60,699,667 (+)	NCBI		MGSCv36	mm8
Celera	10	62,399,002 - 62,405,430 (+)	NCBI		Celera
Cytogenetic Map	10	B4	NCBI
cM Map	10	32.18	NCBI

Prf1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	29,789,040 - 29,794,550 (+)	NCBI		GRCr8
mRatBN7.2	20	29,246,202 - 29,251,712 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	29,246,202 - 29,251,701 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	30,262,194 - 30,267,704 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	29,648,492 - 29,654,002 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	30,390,949 - 30,396,459 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	30,915,294 - 30,920,804 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	30,915,213 - 30,921,382 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	32,706,313 - 32,711,823 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	28,658,367 - 28,663,877 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	28,672,166 - 28,677,670 (+)	NCBI
Celera	20	30,679,378 - 30,684,888 (+)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

Prf1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	20,700,718 - 20,706,929 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	20,700,912 - 20,705,076 (+)	NCBI	ChiLan1.0	ChiLan1.0

PRF1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	82,751,239 - 82,757,941 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	82,756,560 - 82,763,263 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	67,071,141 - 67,078,057 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	69,597,574 - 69,603,070 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	69,597,574 - 69,603,070 (-)	Ensembl	panpan1.1		panPan2

PRF1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	21,497,865 - 21,502,429 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	21,498,249 - 21,500,864 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	21,630,717 - 21,633,264 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	21,771,953 - 21,776,587 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	21,772,387 - 21,775,002 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	21,669,548 - 21,672,095 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	21,875,818 - 21,878,365 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	22,227,730 - 22,230,277 (-)	NCBI		UU_Cfam_GSD_1.0

Prf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	59,564,718 - 59,568,196 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	8,057,874 - 8,060,695 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	8,057,874 - 8,060,695 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRF1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	73,512,769 - 73,520,202 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	73,515,306 - 73,520,256 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	79,363,495 - 79,368,376 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Prf1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	4,679,521 - 4,681,627 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	4,679,451 - 4,681,627 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium		18
Low	24	2	13
Below cutoff	11		31

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007963157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007963158	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000006367 ⟹ ENSCSAP00000004572

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	9	60,692,600 - 60,698,465 (+)	Ensembl

RefSeq Acc Id:

XM_007963157 ⟹ XP_007961348

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	9	60,692,545 - 60,698,000 (+)	NCBI
Vero_WHO_p1.0	NW_023666048	21,417,046 - 21,423,266 (+)	NCBI

Sequence:

show sequence

GGGGCAGGAAGTAGAAGTGATCTGAGTGGTGGCTGGTGCAAGGAGCCACAGTGGGCTGCCTGGG
GGGCTGACGCCACCATTCCAGGAGCCTTGGTGAAGAAAGGACATCCGCCTGTGTAGCTGCTTCT
CCATACAGGACTCCAGCTCCATGGCGGCCTGCCTGCTCCTCCTGGGCATCCTTCTCCTGCTGCT
GCCCCTGCCAGTCCCTGCTCCCTGCCACACAGCCACACGCTCAGAGTGCAAGCGCAGCCACAAG
TTTGTGCCCGGTGCATGGCTGGCCGGGGAGGGTGTGGACGTGACCAGCCTCCGCCGCTCAGGCT
CCTTCCCAGTAGACACACAAAGGTTCCTGCGGCCCGACGGCACCTGCACCCTCTGTGAAAATGC
CCTACAGGAGGGCACCCTCCAGCGCCTGCCCCTGGCACTCACCAACTGGCGGGCCCAGGGCTCT
GGCTGCCAGCGCCATGTAGCCAGGGCCAAAGTCAGCTCCACTGAAGCTGTGGCCCGGGATGCGG
CTCGTAGCATCCGCAACGACTGGAAGGTCGGGCTGGATGTGACTCCCCACCCCACCGGCAACGT
GCATGTGTCTGTGGCCGGCTCACACTCACAGGCAGCCAACTTTGCAGCCCAGAAGACCCACCAG
GACCAGTACAGCTTCAGCACTGACACAGTGGAGTGTCGCTTCTACAGTTACCATGTGGTACACA
CTCCCCCGCTGCACCCTGACTTCAAGAGGGCCCTCGGGGACCTGCCCCTCCACTTCAACGCCTC
CACCCAGTCCGCCTACCTCAGGCTCATCTCCAACTACGGCACCCACTTCATCCGGGCTGTGGAG
CTGGGCGGCCGCATCTCGGCCCTCACTGCCCTGCGCACCTGTGAACTGGCCCTGGAAGGGCTCA
CGGACGATGAGGTGGATGACTGCCTGAACGTCGAGGCCCAGGTCAACATAGGCGCCCGCGGCAG
CTCCTCTGCCGAAGCCAAAGCCTGTGAGGAGAAGAAGAAGAAGCACAAGATGACGGCCTCCTTC
CACCAAACCTACCGGGAGCGCCATTCGGAAGTGGTTGGCGGCCATCACACCTCCATTAACGACC
TGCTGTTCGGGAGCCAGGCCGGGCCTGAGCAGTACTCAGCCTGGGTGAACTCGCTGCTCGGCAG
CCCTGGCCTGGTGGACTACAGCCTGGAACCCCTGCATGTGCTGCTGGACAGCCAGGACCCGCGG
CGGGAGGCACTGAGGAGGGCCCTGAGTCAGTACCTGACGGACAGGGCTCGCTGGAGGGACTGCA
GCCGGCCGTGCCCACCGGGGCGGCAGAAGAGCCCCCGAGACCCGTGCCAGTGTGTGTGCCATGG
CTCAGCGGTCACCACCCAGGACTGCTGCCCTCGACAGAGGGGCCTGGCCCAGCTAGAGGTGACC
TTCATCCAAGCCTGGGGCCTGTGGGGGGACTGGTTCACTGCCACGGATGCCTATGTGAAGGTGT
TCTTTGGTGGCCAGGAGCTCAGGACGAACACCCAGTGGAGTAATAACAACCCCATCTGGTCAAT
GCCACTGGATTTTGGGGATGTGCTCCTGGCCACAGGGGGGCCCCTGAGGTTGCAGGTCTGGGAT
CAGGACTCTGGCTGGGACGATGACCTCCTTGGCACCTGTGATCAGGCTCCCAAGTCTGGTTCCC
ATGAGGCGAGATGCAACCTGAAACATGGCCACCTGAAATTCCGCTATCACGCCAGGTGCTTGCC
CCACCTGGGAGGAGGCACCTGCCTGGACTACGTCCCCCAGATGCTTCTGGGGGAGCCTCCAGGA
AACCGGAGTGGGGCCGTGTGGTGAGAACAGTGAGCTTGGAGAGGACTCGTGTGCTTGGACTGAA
GGGGTTCTCACAGTGGGAGCCAGGGTTGTCTTCGTATTCCCATTAGACCAAGCTCGTCCAACCC
GAGGCCCGCATGTGGCCCGGGATGGCTTTGAATGTGGCCCAACACAAATTCGCAAACTTTCTTA
AAACATTATGAGATTTTTGTTTTGCGATTTTATTTTTTTTTAGCTCATCAGCTATGGTTAGTGT
TAGTGTATTTTATGTGTGGCCCAACATGATTCTTCTTCCGATGTGGCCCAGAGAAGCCAAAAGA
TTGGACACCCATCAGATAGATGGAAAAGGGAGACTCAGACTATTTTTCAGGGAGGTGGCTGGGT
ATACACGCCAACCCCGATTCACCCTGTCCAAACTGCCTAAGCCCTCTGTCATTCTCAAGCCCTG
CAGTCACAGCTACACAAATCACAGCTTCAGCCAGGAGCTGGGCAGAAAGGCCAAGCTCCCACCA
GGCTGCCCAGGACTGGTCTTTTAGGACCCTTCCCTTGAGGCCTCTGTGGTGTGGCAAAGCCACT
TCATTGCTTTAACTGGAGTCCCATCAGCTCCAGCTGCTCTGTCTTCCTTGCCCACAATGCTTTG
CCCCTGAGACAAATGGAGGCCTGTCCTGACCTGTCTCACCGTGTACATAGCTTGATAAAGGGCC
AATAAATATGATGTTCTGGTGATCA

hide sequence

RefSeq Acc Id:

XM_007963158 ⟹ XP_007961349

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	9	60,692,544 - 60,698,000 (+)	NCBI
Vero_WHO_p1.0	NW_023666048	21,418,998 - 21,423,720 (+)	NCBI

Sequence:

show sequence

CGGGGCAGGAAGTAGAAGTGATCTGAGTGGTGGCTGGTGCAAGGAGCCACAGTGGGCTGCCTGG
GGGGCTGACGCCACCATTCCAGGAGCCTTGGTGAAGAAAGGACATCCGCCTGTGTAGCTGCTTC
TCCATACAGGACTCCAGAGCCCAAGTGCCCCCTGTCTCTGCAGCTCCATGGCGGCCTGCCTGCT
CCTCCTGGGCATCCTTCTCCTGCTGCTGCCCCTGCCAGTCCCTGCTCCCTGCCACACAGCCACA
CGCTCAGAGTGCAAGCGCAGCCACAAGTTTGTGCCCGGTGCATGGCTGGCCGGGGAGGGTGTGG
ACGTGACCAGCCTCCGCCGCTCAGGCTCCTTCCCAGTAGACACACAAAGGTTCCTGCGGCCCGA
CGGCACCTGCACCCTCTGTGAAAATGCCCTACAGGAGGGCACCCTCCAGCGCCTGCCCCTGGCA
CTCACCAACTGGCGGGCCCAGGGCTCTGGCTGCCAGCGCCATGTAGCCAGGGCCAAAGTCAGCT
CCACTGAAGCTGTGGCCCGGGATGCGGCTCGTAGCATCCGCAACGACTGGAAGGTCGGGCTGGA
TGTGACTCCCCACCCCACCGGCAACGTGCATGTGTCTGTGGCCGGCTCACACTCACAGGCAGCC
AACTTTGCAGCCCAGAAGACCCACCAGGACCAGTACAGCTTCAGCACTGACACAGTGGAGTGTC
GCTTCTACAGTTACCATGTGGTACACACTCCCCCGCTGCACCCTGACTTCAAGAGGGCCCTCGG
GGACCTGCCCCTCCACTTCAACGCCTCCACCCAGTCCGCCTACCTCAGGCTCATCTCCAACTAC
GGCACCCACTTCATCCGGGCTGTGGAGCTGGGCGGCCGCATCTCGGCCCTCACTGCCCTGCGCA
CCTGTGAACTGGCCCTGGAAGGGCTCACGGACGATGAGGTGGATGACTGCCTGAACGTCGAGGC
CCAGGTCAACATAGGCGCCCGCGGCAGCTCCTCTGCCGAAGCCAAAGCCTGTGAGGAGAAGAAG
AAGAAGCACAAGATGACGGCCTCCTTCCACCAAACCTACCGGGAGCGCCATTCGGAAGTGGTTG
GCGGCCATCACACCTCCATTAACGACCTGCTGTTCGGGAGCCAGGCCGGGCCTGAGCAGTACTC
AGCCTGGGTGAACTCGCTGCTCGGCAGCCCTGGCCTGGTGGACTACAGCCTGGAACCCCTGCAT
GTGCTGCTGGACAGCCAGGACCCGCGGCGGGAGGCACTGAGGAGGGCCCTGAGTCAGTACCTGA
CGGACAGGGCTCGCTGGAGGGACTGCAGCCGGCCGTGCCCACCGGGGCGGCAGAAGAGCCCCCG
AGACCCGTGCCAGTGTGTGTGCCATGGCTCAGCGGTCACCACCCAGGACTGCTGCCCTCGACAG
AGGGGCCTGGCCCAGCTAGAGGTGACCTTCATCCAAGCCTGGGGCCTGTGGGGGGACTGGTTCA
CTGCCACGGATGCCTATGTGAAGGTGTTCTTTGGTGGCCAGGAGCTCAGGACGAACACCCAGTG
GAGTAATAACAACCCCATCTGGTCAATGCCACTGGATTTTGGGGATGTGCTCCTGGCCACAGGG
GGGCCCCTGAGGTTGCAGGTCTGGGATCAGGACTCTGGCTGGGACGATGACCTCCTTGGCACCT
GTGATCAGGCTCCCAAGTCTGGTTCCCATGAGGCGAGATGCAACCTGAAACATGGCCACCTGAA
ATTCCGCTATCACGCCAGGTGCTTGCCCCACCTGGGAGGAGGCACCTGCCTGGACTACGTCCCC
CAGATGCTTCTGGGGGAGCCTCCAGGAAACCGGAGTGGGGCCGTGTGGTGAGAACAGTGAGCTT
GGAGAGGACTCGTGTGCTTGGACTGAAGGGGTTCTCACAGTGGGAGCCAGGGTTGTCTTCGTAT
TCCCATTAGACCAAGCTCGTCCAACCCGAGGCCCGCATGTGGCCCGGGATGGCTTTGAATGTGG
CCCAACACAAATTCGCAAACTTTCTTAAAACATTATGAGATTTTTGTTTTGCGATTTTATTTTT
TTTTAGCTCATCAGCTATGGTTAGTGTTAGTGTATTTTATGTGTGGCCCAACATGATTCTTCTT
CCGATGTGGCCCAGAGAAGCCAAAAGATTGGACACCCATCAGATAGATGGAAAAGGGAGACTCA
GACTATTTTTCAGGGAGGTGGCTGGGTATACACGCCAACCCCGATTCACCCTGTCCAAACTGCC
TAAGCCCTCTGTCATTCTCAAGCCCTGCAGTCACAGCTACACAAATCACAGCTTCAGCCAGGAG
CTGGGCAGAAAGGCCAAGCTCCCACCAGGCTGCCCAGGACTGGTCTTTTAGGACCCTTCCCTTG
AGGCCTCTGTGGTGTGGCAAAGCCACTTCATTGCTTTAACTGGAGTCCCATCAGCTCCAGCTGC
TCTGTCTTCCTTGCCCACAATGCTTTGCCCCTGAGACAAATGGAGGCCTGTCCTGACCTGTCTC
ACCGTGTACATAGCTTGATAAAGGGCCAATAAATATGATGTTCTGGTGATCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007961348	(Get FASTA)	NCBI Sequence Viewer
	XP_007961349	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000004572.1

RefSeq Acc Id:	XP_007961349 ⟸ XM_007963158
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9R7I3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007961348 ⟸ XM_007963157
- Peptide Label:	isoform X2
- UniProtKB:	A0A0D9R7I3 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000004572 ⟸ ENSCSAT00000006367

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000008314	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000006367.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.150	UniProtKB/TrEMBL
InterPro	C2_dom	UniProtKB/TrEMBL
	C2_domain_sf	UniProtKB/TrEMBL
	MACPF	UniProtKB/TrEMBL
	MACPF_CS	UniProtKB/TrEMBL
	Perforin-1_C2	UniProtKB/TrEMBL
KEGG Report	csab:103216048	UniProtKB/TrEMBL
NCBI Gene	PRF1	ENTREZGENE
PANTHER	PERFORIN-1	UniProtKB/TrEMBL
	PERFORIN-1	UniProtKB/TrEMBL
Pfam	MACPF	UniProtKB/TrEMBL
	PF00168	UniProtKB/TrEMBL
PROSITE	MACPF_1	UniProtKB/TrEMBL
	MACPF_2	UniProtKB/TrEMBL
	PS50004	UniProtKB/TrEMBL
SMART	MACPF	UniProtKB/TrEMBL
	SM00239	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49562	UniProtKB/TrEMBL
UniProt	A0A0D9R7I3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM