DSCAML1 (DS cell adhesion molecule like 1) - Rat Genome Database

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Gene: DSCAML1 (DS cell adhesion molecule like 1) Chlorocebus sabaeus
Analyze
Symbol: DSCAML1
Name: DS cell adhesion molecule like 1
RGD ID: 18496218
Description: ENCODES a protein that exhibits cell-cell adhesion mediator activity (inferred); protein homodimerization activity (inferred); INVOLVED IN negative regulation of cell adhesion (ortholog); ASSOCIATED WITH CD3epsilon deficiency (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); FOUND IN axon (inferred); cell surface (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Down syndrome cell adhesion molecule-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11108,801,895 - 109,167,011 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1108,802,452 - 108,906,272 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604316,884,696 - 17,253,166 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (IEA)
cell surface  (IEA)
membrane  (IEA)
plasma membrane  (IEA)
synapse  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
DSCAML1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11108,801,895 - 109,167,011 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1108,802,452 - 108,906,272 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604316,884,696 - 17,253,166 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DSCAML1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811117,427,772 - 117,817,514 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11117,427,772 - 117,817,525 (-)EnsemblGRCh38hg38GRCh38
GRCh3711117,298,488 - 117,688,229 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611116,803,699 - 117,173,186 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411116,803,698 - 117,173,186NCBI
Celera11114,456,148 - 114,825,824 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11113,232,070 - 113,601,503 (-)NCBIHuRef
CHM1_111117,184,136 - 117,553,548 (-)NCBICHM1_1
T2T-CHM13v2.011117,444,420 - 117,833,926 (-)NCBIT2T-CHM13v2.0
Dscaml1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39945,338,735 - 45,665,011 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl945,337,926 - 45,665,010 (+)EnsemblGRCm39 Ensembl
GRCm38945,427,433 - 45,753,713 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl945,426,628 - 45,753,712 (+)EnsemblGRCm38mm10GRCm38
MGSCv37945,238,376 - 45,561,796 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36945,177,638 - 45,504,708 (+)NCBIMGSCv36mm8
Celera942,711,034 - 43,036,189 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Dscaml1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8854,637,054 - 54,954,042 (+)NCBIGRCr8
mRatBN7.2845,740,298 - 46,057,322 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl845,740,298 - 46,057,320 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx851,241,621 - 51,558,558 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0849,520,390 - 49,837,319 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0847,384,518 - 47,701,590 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0849,733,835 - 50,056,115 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl849,737,798 - 50,055,560 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0848,363,393 - 48,680,159 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4848,406,373 - 48,723,775 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1848,415,176 - 48,732,542 (+)NCBI
Celera845,323,185 - 45,640,085 (+)NCBICelera
Cytogenetic Map8q22NCBI
Dscaml1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541218,708,993 - 19,022,523 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541218,708,444 - 19,022,538 (-)NCBIChiLan1.0ChiLan1.0
DSCAML1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29118,129,935 - 118,499,279 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111119,234,895 - 119,604,479 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011112,263,509 - 112,632,332 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111116,196,121 - 116,564,715 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11116,196,677 - 116,302,262 (-)Ensemblpanpan1.1panPan2
DSCAML1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1515,839,504 - 16,187,465 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl515,826,726 - 16,186,880 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha515,892,647 - 16,236,733 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0515,784,153 - 16,128,741 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl515,784,119 - 16,128,732 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1515,922,210 - 16,266,654 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0515,825,496 - 16,169,644 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0515,867,121 - 16,211,866 (+)NCBIUU_Cfam_GSD_1.0
Dscaml1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494799,704,544 - 100,018,127 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365422,620,469 - 2,939,578 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365422,619,910 - 2,939,578 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DSCAML1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl944,785,701 - 45,147,140 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1944,785,142 - 45,153,256 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2949,858,136 - 49,975,441 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Dscaml1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478412,854,420 - 13,183,132 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478412,853,870 - 13,183,224 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 9
Low 34 13 51
Below cutoff 2 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008021021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000000666   ⟹   ENSCSAP00000015398
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1108,802,452 - 108,906,272 (-)Ensembl
RefSeq Acc Id: XM_008021021   ⟹   XP_008019212
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11108,801,895 - 109,167,011 (-)NCBI
Vero_WHO_p1.0NW_02366604316,884,696 - 17,253,166 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008019212 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015398.1
Reference Protein Sequences
RefSeq Acc Id: XP_008019212   ⟸   XM_008021021
- UniProtKB: A0A0D9S3F9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015398   ⟸   ENSCSAT00000000666


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002669 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000666.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
NCBI Gene DSCAML1 ENTREZGENE
PANTHER BASIGIN RELATED UniProtKB/TrEMBL
  DOWN SYNDROME CELL ADHESION MOLECULE 3, ISOFORM E-RELATED UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
UniProt A0A0D9S3F9 ENTREZGENE, UniProtKB/TrEMBL