LOC103248766 (fasciculation and elongation protein zeta-1) - Rat Genome Database

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Gene: LOC103248766 (fasciculation and elongation protein zeta-1) Chlorocebus sabaeus
Analyze
Symbol: LOC103248766 (Ensembl: FEZ1)
Name: fasciculation and elongation protein zeta-1 (Ensembl:fasciculation and elongation protein zeta 1)
RGD ID: 18468321
Description: ENCODES a protein that exhibits protein kinase C binding (ortholog); INVOLVED IN cellular response to growth factor stimulus (ortholog); establishment of cell polarity (ortholog); establishment of mitochondrion localization (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); holoprosencephaly 11 (ortholog); FOUND IN axon (ortholog); cell projection (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fasciculation and elongation protein zeta 1; FEZ1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,617,835 - 116,668,601 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1116,617,714 - 116,668,574 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660439,401,860 - 9,506,604 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LOC103248766
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,617,835 - 116,668,601 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1116,617,714 - 116,668,574 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660439,401,860 - 9,506,604 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
FEZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811125,442,881 - 125,496,265 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11125,442,881 - 125,592,568 (-)EnsemblGRCh38hg38GRCh38
GRCh3711125,312,777 - 125,366,161 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,820,858 - 124,871,333 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411124,863,305 - 124,871,333NCBI
Celera11122,475,971 - 122,526,454 (-)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11121,257,207 - 121,307,713 (-)NCBIHuRef
CHM1_111125,201,870 - 125,252,371 (-)NCBICHM1_1
T2T-CHM13v2.011125,471,573 - 125,524,945 (-)NCBIT2T-CHM13v2.0
Fez1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39936,732,694 - 36,790,220 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl936,733,160 - 36,790,220 (+)EnsemblGRCm39 Ensembl
GRCm38936,821,398 - 36,878,926 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl936,821,864 - 36,878,924 (+)EnsemblGRCm38mm10GRCm38
MGSCv37936,651,244 - 36,686,225 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36936,582,480 - 36,628,593 (+)NCBIMGSCv36mm8
Celera934,040,032 - 34,083,023 (+)NCBICelera
Cytogenetic Map9A4NCBI
cM Map920.69NCBI
Fez1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8844,733,288 - 44,778,519 (+)NCBIGRCr8
mRatBN7.2836,544,462 - 36,589,684 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl836,544,535 - 36,589,683 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx840,554,068 - 40,599,499 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0838,837,136 - 38,882,569 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0836,700,025 - 36,745,464 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0839,305,128 - 39,350,270 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,305,128 - 39,350,270 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,307,579 - 39,353,313 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,078,328 - 38,123,983 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1838,087,093 - 38,132,749 (+)NCBI
Celera837,851,976 - 37,897,230 (-)NCBICelera
Cytogenetic Map8q22NCBI
Fez1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541226,477,301 - 26,531,354 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541226,477,995 - 26,530,686 (-)NCBIChiLan1.0ChiLan1.0
FEZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29126,140,622 - 126,191,057 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111127,245,630 - 127,296,035 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011120,272,187 - 120,322,600 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111124,186,241 - 124,236,403 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11124,182,901 - 124,236,403 (-)Ensemblpanpan1.1panPan2
FEZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.159,001,927 - 9,044,330 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl59,001,989 - 9,044,332 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha59,045,434 - 9,088,812 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.058,940,817 - 8,984,967 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl58,940,786 - 8,984,968 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.159,012,637 - 9,056,170 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.058,982,968 - 9,026,843 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.059,019,529 - 9,062,951 (+)NCBIUU_Cfam_GSD_1.0
Fez1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947107,623,764 - 107,669,772 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367431,871,664 - 1,903,245 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367431,871,808 - 1,917,370 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FEZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl952,621,183 - 52,672,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1952,621,175 - 52,672,660 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2958,321,965 - 58,348,192 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Fez1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249271,469,025 - 1,512,790 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249271,470,218 - 1,512,780 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20 60
Low 16 13
Below cutoff 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000000326   ⟹   ENSCSAP00000015729
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1116,617,714 - 116,668,574 (-)Ensembl
RefSeq Acc Id: XM_008021388   ⟹   XP_008019579
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11116,617,835 - 116,668,601 (-)NCBI
Vero_WHO_p1.0NW_0236660439,401,860 - 9,506,603 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008021389   ⟹   XP_008019580
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11116,617,835 - 116,668,322 (-)NCBI
Vero_WHO_p1.0NW_0236660439,402,197 - 9,506,603 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038005014   ⟹   XP_037860942
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660439,401,860 - 9,506,604 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008019579 (Get FASTA)   NCBI Sequence Viewer  
  XP_008019580 (Get FASTA)   NCBI Sequence Viewer  
  XP_037860942 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015729
  ENSCSAP00000015729.1
Reference Protein Sequences
RefSeq Acc Id: XP_008019579   ⟸   XM_008021388
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S4E0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008019580   ⟸   XM_008021389
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S4E0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000015729   ⟸   ENSCSAT00000000326
RefSeq Acc Id: XP_037860942   ⟸   XM_038005014
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002308 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000326.1 UniProtKB/TrEMBL
InterPro FEZ UniProtKB/TrEMBL
KEGG Report csab:103248766 UniProtKB/TrEMBL
NCBI Gene FEZ1 ENTREZGENE
PANTHER PTHR12394 UniProtKB/TrEMBL
  PTHR12394:SF4 UniProtKB/TrEMBL
Pfam FEZ UniProtKB/TrEMBL
UniProt A0A0D9S4E0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-08 LOC103248766  fasciculation and elongation protein zeta-1  FEZ1  fasciculation and elongation protein zeta 1  Symbol and/or name change 5135510 APPROVED