RABGAP1 (RAB GTPase activating protein 1) - Rat Genome Database

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Gene: RABGAP1 (RAB GTPase activating protein 1) Chlorocebus sabaeus
Analyze
Symbol: RABGAP1
Name: RAB GTPase activating protein 1
RGD ID: 18466995
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); small GTPase binding (inferred); INVOLVED IN regulation of cilium assembly (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103239903; rab GTPase-activating protein 1; uncharacterized LOC103239903
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11215,028,205 - 15,198,953 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1215,028,203 - 15,177,626 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666079865,318 - 1,040,790 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
RABGAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11215,028,205 - 15,198,953 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1215,028,203 - 15,177,626 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666079865,318 - 1,040,790 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RABGAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389122,931,671 - 123,104,866 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9122,940,833 - 123,104,866 (+)EnsemblGRCh38hg38GRCh38
GRCh379125,703,299 - 125,867,145 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369124,743,138 - 124,906,531 (+)NCBINCBI36Build 36hg18NCBI36
Build 349122,782,870 - 122,946,250NCBI
Celera996,351,607 - 96,515,424 (+)NCBICelera
Cytogenetic Map9q33.2-q33.3NCBI
HuRef995,318,127 - 95,482,201 (+)NCBIHuRef
CHM1_19125,851,805 - 126,015,462 (+)NCBICHM1_1
T2T-CHM13v2.09135,128,522 - 135,302,077 (+)NCBIT2T-CHM13v2.0
Rabgap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39237,333,274 - 37,463,653 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl237,333,291 - 37,456,466 (+)EnsemblGRCm39 Ensembl
GRCm38237,443,263 - 37,573,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl237,443,279 - 37,566,454 (+)EnsemblGRCm38mm10GRCm38
MGSCv37237,298,805 - 37,421,957 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36237,265,294 - 37,388,446 (+)NCBIMGSCv36mm8
Celera237,127,293 - 37,251,801 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.19NCBI
Rabgap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8341,617,784 - 41,735,795 (+)NCBIGRCr8
mRatBN7.2321,208,012 - 21,326,013 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl321,208,055 - 21,326,013 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx324,676,385 - 24,794,460 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0333,261,349 - 33,379,418 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0331,072,090 - 31,190,304 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0321,698,032 - 21,815,383 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl321,698,032 - 21,815,379 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0326,937,207 - 27,053,945 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4317,204,810 - 17,322,894 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1317,125,169 - 17,217,685 (+)NCBI
Celera319,643,578 - 19,761,555 (+)NCBICelera
Cytogenetic Map3q11NCBI
Rabgap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554194,869,799 - 5,023,321 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554194,869,799 - 5,031,430 (-)NCBIChiLan1.0ChiLan1.0
RABGAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21116,244,231 - 16,410,384 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1916,246,579 - 16,412,777 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0994,066,218 - 94,232,659 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19122,399,778 - 122,565,906 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9122,415,882 - 122,564,283 (+)Ensemblpanpan1.1panPan2
RABGAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1959,692,621 - 59,860,392 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl959,694,098 - 59,836,532 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha958,887,930 - 59,055,537 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0960,613,022 - 60,779,721 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl960,614,598 - 60,779,703 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1959,371,070 - 59,538,494 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0959,686,097 - 59,853,500 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0959,778,987 - 59,946,247 (-)NCBIUU_Cfam_GSD_1.0
Rabgap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947191,645,998 - 191,806,955 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648711,414,463 - 11,575,471 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648711,414,454 - 11,575,423 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RABGAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1263,857,513 - 264,030,574 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11263,857,501 - 264,030,575 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21297,320,617 - 297,478,637 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Rabgap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476011,818,408 - 12,004,005 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476011,818,349 - 12,003,955 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 60
Low 20
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000011524   ⟹   ENSCSAP00000009591
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1215,028,203 - 15,177,626 (-)Ensembl
RefSeq Acc Id: XM_008006337   ⟹   XP_008004528
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11215,028,205 - 15,194,006 (-)NCBI
Vero_WHO_p1.0NW_023666079874,798 - 1,040,725 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008006338   ⟹   XP_008004529
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11215,028,205 - 15,198,953 (-)NCBI
Vero_WHO_p1.0NW_023666079865,318 - 1,040,790 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008006339   ⟹   XP_008004530
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11215,028,205 - 15,177,516 (-)NCBI
Vero_WHO_p1.0NW_023666079891,294 - 1,040,790 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037994091   ⟹   XP_037850019
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666079865,318 - 1,040,790 (+)NCBI
RefSeq Acc Id: XM_037994092   ⟹   XP_037850020
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666079868,015 - 1,040,790 (+)NCBI
RefSeq Acc Id: XM_037994093   ⟹   XP_037850021
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666079891,361 - 1,040,790 (+)NCBI
RefSeq Acc Id: XM_037994094   ⟹   XP_037850022
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666079891,222 - 1,040,790 (+)NCBI
RefSeq Acc Id: XM_037994095   ⟹   XP_037850023
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666079927,434 - 1,040,790 (+)NCBI
RefSeq Acc Id: XM_037994096   ⟹   XP_037850024
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666079969,467 - 1,039,207 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008004529   ⟸   XM_008006338
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RLV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008004528   ⟸   XM_008006337
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RLV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008004530   ⟸   XM_008006339
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RLV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000009591   ⟸   ENSCSAT00000011524
RefSeq Acc Id: XP_037850019   ⟸   XM_037994091
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RLV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037850020   ⟸   XM_037994092
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RLV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037850022   ⟸   XM_037994094
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RLV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037850021   ⟸   XM_037994093
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RLV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037850023   ⟸   XM_037994095
- Peptide Label: isoform X4
RefSeq Acc Id: XP_037850024   ⟸   XM_037994096
- Peptide Label: isoform X5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013436 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011524.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 1 UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/TrEMBL
InterPro Kinesin-like UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/TrEMBL
  Rab-GTPase-TBC_dom UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/TrEMBL
KEGG Report csab:103239900 UniProtKB/TrEMBL
NCBI Gene RABGAP1 ENTREZGENE
PANTHER RAB GTPASE-ACTIVATING PROTEIN 1 UniProtKB/TrEMBL
  RAB GTPASE-ACTIVATING PROTEIN 1-LIKE UniProtKB/TrEMBL
Pfam DUF3694 UniProtKB/TrEMBL
  PID UniProtKB/TrEMBL
  RabGAP-TBC UniProtKB/TrEMBL
PROSITE PID UniProtKB/TrEMBL
  TBC_RABGAP UniProtKB/TrEMBL
SMART PTB UniProtKB/TrEMBL
  TBC UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47923 UniProtKB/TrEMBL
UniProt A0A0D9RLV2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-03 RABGAP1  RAB GTPase activating protein 1  LOC103239903  uncharacterized LOC103239903  Data merged from RGD:18580251 737654 PROVISIONAL