PHACTR1 (phosphatase and actin regulator 1) - Rat Genome Database

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Gene: PHACTR1 (phosphatase and actin regulator 1) Chlorocebus sabaeus
Analyze
Symbol: PHACTR1
Name: phosphatase and actin regulator 1
RGD ID: 18395727
Description: ENCODES a protein that exhibits protein phosphatase 1 binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); positive regulation of gene expression (ortholog); regulation of modification of postsynaptic structure (ortholog); ASSOCIATED WITH Acute Coronary Syndrome (ortholog); ARTERIAL DISSECTION (ortholog); atherosclerosis (ortholog); FOUND IN cytoplasm (ortholog); glutamatergic synapse (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11758,859,456 - 59,440,969 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1758,862,828 - 59,133,298 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604412,759,821 - 13,333,695 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (IEA)
glutamatergic synapse  (ISO)
nucleus  (IEA,ISO)
postsynapse  (ISO)
synapse  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PHACTR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11758,859,456 - 59,440,969 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1758,862,828 - 59,133,298 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604412,759,821 - 13,333,695 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PHACTR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38612,716,767 - 13,287,837 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl612,716,312 - 13,290,446 (+)EnsemblGRCh38hg38GRCh38
GRCh37612,716,999 - 13,288,069 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36612,825,819 - 13,395,507 (+)NCBINCBI36Build 36hg18NCBI36
Celera613,945,879 - 14,520,501 (+)NCBICelera
Cytogenetic Map6p24.1NCBI
HuRef612,649,580 - 13,225,071 (+)NCBIHuRef
CHM1_1612,719,328 - 13,290,404 (+)NCBICHM1_1
T2T-CHM13v2.0612,585,196 - 13,161,093 (+)NCBIT2T-CHM13v2.0
Phactr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391342,833,909 - 43,292,002 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1342,834,099 - 43,292,002 (+)EnsemblGRCm39 Ensembl
GRCm381342,680,374 - 43,138,526 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1342,680,623 - 43,138,526 (+)EnsemblGRCm38mm10GRCm38
MGSCv371342,775,992 - 43,233,895 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361342,691,595 - 43,149,498 (+)NCBIMGSCv36mm8
Celera1343,759,051 - 44,223,388 (+)NCBICelera
Cytogenetic Map13A4NCBI
cM Map1321.05NCBI
Phactr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81721,769,006 - 22,246,227 (-)NCBIGRCr8
mRatBN7.21721,560,364 - 22,040,166 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1721,562,721 - 22,039,831 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1721,452,066 - 21,925,681 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01723,055,730 - 23,529,379 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01721,379,161 - 21,852,788 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01723,245,423 - 23,761,207 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01725,209,368 - 25,713,282 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41727,393,237 - 27,884,127 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11727,395,233 - 27,885,918 (-)NCBI
Celera1721,259,994 - 21,732,655 (-)NCBICelera
Cytogenetic Map17p14-p12NCBI
Phactr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554651,395,088 - 1,913,847 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554651,395,418 - 1,915,820 (-)NCBIChiLan1.0ChiLan1.0
PHACTR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2527,369,901 - 27,944,831 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1623,359,830 - 23,934,840 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0612,560,862 - 13,136,126 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1612,920,920 - 13,508,965 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl612,922,871 - 13,505,609 (+)Ensemblpanpan1.1panPan2
PHACTR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13512,233,152 - 12,745,031 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3512,491,067 - 12,741,754 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3512,140,823 - 12,694,920 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03512,289,444 - 12,843,408 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3512,291,040 - 12,844,113 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13512,116,414 - 12,670,075 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03512,167,394 - 12,723,499 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03513,491,510 - 14,046,540 (+)NCBIUU_Cfam_GSD_1.0
Phactr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494611,773,444 - 12,269,374 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493653442,433 - 536,171 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493653442,354 - 323,735 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHACTR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl79,105,874 - 9,666,881 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.179,105,422 - 9,666,886 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.279,692,832 - 9,955,704 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Phactr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475612,934,212 - 13,447,326 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475612,935,048 - 13,449,312 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 4 44
Low 32 20 16
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007973663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007973664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007973665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007973666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007973667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007973668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007973669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007973670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000005569   ⟹   ENSCSAP00000003787
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1758,862,828 - 59,133,298 (-)Ensembl
RefSeq Acc Id: XM_007973663   ⟹   XP_007971854
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11758,859,457 - 59,440,122 (-)NCBI
Vero_WHO_p1.0NW_02366604412,759,822 - 13,333,695 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007973664   ⟹   XP_007971855
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11758,859,457 - 59,440,122 (-)NCBI
Vero_WHO_p1.0NW_02366604412,761,152 - 13,333,695 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007973665   ⟹   XP_007971856
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11758,859,457 - 59,440,969 (-)NCBI
Vero_WHO_p1.0NW_02366604412,759,821 - 13,333,695 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007973666   ⟹   XP_007971857
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11758,859,457 - 59,440,734 (-)NCBI
Vero_WHO_p1.0NW_02366604412,759,821 - 13,333,695 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007973667   ⟹   XP_007971858
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11758,859,457 - 59,440,825 (-)NCBI
Vero_WHO_p1.0NW_02366604412,759,831 - 13,333,695 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007973668   ⟹   XP_007971859
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11758,859,457 - 59,440,825 (-)NCBI
Vero_WHO_p1.0NW_02366604412,759,831 - 13,333,695 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007973669   ⟹   XP_007971860
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11758,859,456 - 59,193,200 (-)NCBI
Vero_WHO_p1.0NW_02366604412,999,946 - 13,333,695 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038005563   ⟹   XP_037861491
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604413,057,405 - 13,333,695 (+)NCBI
RefSeq Acc Id: XM_038005564   ⟹   XP_037861492
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604413,057,408 - 13,330,292 (+)NCBI
RefSeq Acc Id: XM_038005565   ⟹   XP_037861493
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604412,759,827 - 13,330,292 (+)NCBI
RefSeq Acc Id: XM_038005566   ⟹   XP_037861494
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604412,759,832 - 13,330,292 (+)NCBI
RefSeq Acc Id: XM_038005567   ⟹   XP_037861495
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604412,759,831 - 13,333,695 (+)NCBI
RefSeq Acc Id: XM_038005568   ⟹   XP_037861496
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604412,761,160 - 13,333,695 (+)NCBI
RefSeq Acc Id: XM_038005569   ⟹   XP_037861497
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604412,999,946 - 13,333,695 (+)NCBI
RefSeq Acc Id: XM_038005570   ⟹   XP_037861498
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604412,999,946 - 13,333,695 (+)NCBI
RefSeq Acc Id: XM_038005571   ⟹   XP_037861499
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604413,001,428 - 13,330,292 (+)NCBI
RefSeq Acc Id: XM_038005572   ⟹   XP_037861500
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604412,999,948 - 13,333,695 (+)NCBI
RefSeq Acc Id: XM_038005573   ⟹   XP_037861501
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604412,999,948 - 13,333,695 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007971860   ⟸   XM_007973669
- Peptide Label: isoform X7
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007971856   ⟸   XM_007973665
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007971859   ⟸   XM_007973668
- Peptide Label: isoform X5
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007971858   ⟸   XM_007973667
- Peptide Label: isoform X5
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007971857   ⟸   XM_007973666
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007971854   ⟸   XM_007973663
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007971855   ⟸   XM_007973664
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000003787   ⟸   ENSCSAT00000005569
RefSeq Acc Id: XP_037861493   ⟸   XM_038005565
- Peptide Label: isoform X4
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861495   ⟸   XM_038005567
- Peptide Label: isoform X5
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861494   ⟸   XM_038005566
- Peptide Label: isoform X4
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861496   ⟸   XM_038005568
- Peptide Label: isoform X5
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861498   ⟸   XM_038005570
- Peptide Label: isoform X7
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861497   ⟸   XM_038005569
- Peptide Label: isoform X6
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861500   ⟸   XM_038005572
- Peptide Label: isoform X9
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861501   ⟸   XM_038005573
- Peptide Label: isoform X9
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861499   ⟸   XM_038005571
- Peptide Label: isoform X8
RefSeq Acc Id: XP_037861491   ⟸   XM_038005563
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037861492   ⟸   XM_038005564
- Peptide Label: isoform X3
- UniProtKB: A0A0D9R598 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000007524 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000005569.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.1750 UniProtKB/TrEMBL
  6.10.140.2130 UniProtKB/TrEMBL
InterPro RPEL_repeat UniProtKB/TrEMBL
NCBI Gene PHACTR1 ENTREZGENE
PANTHER PHOSPHATASE AND ACTIN REGULATOR PHACTR UniProtKB/TrEMBL
  PTHR12751:SF6 UniProtKB/TrEMBL
Pfam RPEL UniProtKB/TrEMBL
PROSITE RPEL UniProtKB/TrEMBL
SMART RPEL UniProtKB/TrEMBL
UniProt A0A0D9R598 ENTREZGENE, UniProtKB/TrEMBL