PHACTR1 (phosphatase and actin regulator 1) - Rat Genome Database

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Gene: PHACTR1 (phosphatase and actin regulator 1) Pan paniscus
Analyze
Symbol: PHACTR1
Name: phosphatase and actin regulator 1
RGD ID: 11677248
Description: ENCODES a protein that exhibits protein phosphatase 1 binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); positive regulation of gene expression (ortholog); regulation of modification of postsynaptic structure (ortholog); ASSOCIATED WITH Acute Coronary Syndrome (ortholog); ARTERIAL DISSECTION (ortholog); atherosclerosis (ortholog); FOUND IN cytoplasm (ortholog); glutamatergic synapse (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100970457; LOC100979637; phosphatase and actin regulator 1-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2527,369,901 - 27,944,831 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1623,359,830 - 23,934,840 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0612,560,862 - 13,136,126 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1612,920,920 - 13,508,965 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl612,922,871 - 13,505,609 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (IEA)
glutamatergic synapse  (ISO)
nucleus  (IEA,ISO)
postsynapse  (ISO)
synapse  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PHACTR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2527,369,901 - 27,944,831 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1623,359,830 - 23,934,840 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0612,560,862 - 13,136,126 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1612,920,920 - 13,508,965 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl612,922,871 - 13,505,609 (+)Ensemblpanpan1.1panPan2
PHACTR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38612,716,767 - 13,287,837 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl612,716,312 - 13,290,446 (+)EnsemblGRCh38hg38GRCh38
GRCh37612,716,999 - 13,288,069 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36612,825,819 - 13,395,507 (+)NCBINCBI36Build 36hg18NCBI36
Celera613,945,879 - 14,520,501 (+)NCBICelera
Cytogenetic Map6p24.1NCBI
HuRef612,649,580 - 13,225,071 (+)NCBIHuRef
CHM1_1612,719,328 - 13,290,404 (+)NCBICHM1_1
T2T-CHM13v2.0612,585,196 - 13,161,093 (+)NCBIT2T-CHM13v2.0
Phactr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391342,833,909 - 43,292,002 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1342,834,099 - 43,292,002 (+)EnsemblGRCm39 Ensembl
GRCm381342,680,374 - 43,138,526 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1342,680,623 - 43,138,526 (+)EnsemblGRCm38mm10GRCm38
MGSCv371342,775,992 - 43,233,895 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361342,691,595 - 43,149,498 (+)NCBIMGSCv36mm8
Celera1343,759,051 - 44,223,388 (+)NCBICelera
Cytogenetic Map13A4NCBI
cM Map1321.05NCBI
Phactr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81721,769,006 - 22,246,227 (-)NCBIGRCr8
mRatBN7.21721,560,364 - 22,040,166 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1721,562,721 - 22,039,831 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1721,452,066 - 21,925,681 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01723,055,730 - 23,529,379 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01721,379,161 - 21,852,788 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01723,245,423 - 23,761,207 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01725,209,368 - 25,713,282 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41727,393,237 - 27,884,127 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11727,395,233 - 27,885,918 (-)NCBI
Celera1721,259,994 - 21,732,655 (-)NCBICelera
Cytogenetic Map17p14-p12NCBI
Phactr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554651,395,088 - 1,913,847 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554651,395,418 - 1,915,820 (-)NCBIChiLan1.0ChiLan1.0
PHACTR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13512,233,152 - 12,745,031 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3512,491,067 - 12,741,754 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3512,140,823 - 12,694,920 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03512,289,444 - 12,843,408 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3512,291,040 - 12,844,113 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13512,116,414 - 12,670,075 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03512,167,394 - 12,723,499 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03513,491,510 - 14,046,540 (+)NCBIUU_Cfam_GSD_1.0
Phactr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494611,773,444 - 12,269,374 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493653442,433 - 536,171 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493653442,354 - 323,735 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHACTR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl79,105,874 - 9,666,881 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.179,105,422 - 9,666,886 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.279,692,832 - 9,955,704 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PHACTR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11758,859,456 - 59,440,969 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1758,862,828 - 59,133,298 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604412,759,821 - 13,333,695 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phactr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475612,934,212 - 13,447,326 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475612,935,048 - 13,449,312 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000032291   ⟹   ENSPPAP00000009648
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl612,922,871 - 13,505,609 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000032293   ⟹   ENSPPAP00000009650
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl612,922,871 - 13,136,156 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000032295   ⟹   ENSPPAP00000009652
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl613,216,345 - 13,505,609 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000032300   ⟹   ENSPPAP00000009657
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl613,491,324 - 13,505,540 (+)Ensembl
RefSeq Acc Id: XM_024928986   ⟹   XP_024784754
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2527,369,901 - 27,944,831 (+)NCBI
NHGRI_mPanPan1623,359,830 - 23,934,840 (+)NCBI
Mhudiblu_PPA_v0612,560,862 - 13,136,126 (+)NCBI
PanPan1.1612,920,920 - 13,508,965 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034961450   ⟹   XP_034817341
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2527,665,347 - 27,944,831 (+)NCBI
NHGRI_mPanPan1623,655,324 - 23,934,840 (+)NCBI
Mhudiblu_PPA_v0612,856,334 - 13,136,126 (+)NCBI
RefSeq Acc Id: XM_034961451   ⟹   XP_034817342
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2527,369,902 - 27,944,831 (+)NCBI
NHGRI_mPanPan1623,359,831 - 23,934,840 (+)NCBI
Mhudiblu_PPA_v0612,560,863 - 13,136,126 (+)NCBI
RefSeq Acc Id: XM_034961452   ⟹   XP_034817343
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2527,369,901 - 27,944,831 (+)NCBI
NHGRI_mPanPan1623,359,830 - 23,934,840 (+)NCBI
Mhudiblu_PPA_v0612,560,862 - 13,136,126 (+)NCBI
RefSeq Acc Id: XM_034961453   ⟹   XP_034817344
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2527,371,492 - 27,944,831 (+)NCBI
NHGRI_mPanPan1623,361,411 - 23,934,840 (+)NCBI
Mhudiblu_PPA_v0612,562,437 - 13,136,126 (+)NCBI
RefSeq Acc Id: XM_034961461   ⟹   XP_034817352
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2527,665,322 - 27,944,831 (+)NCBI
NHGRI_mPanPan1623,655,300 - 23,934,840 (+)NCBI
Mhudiblu_PPA_v0612,856,312 - 13,136,126 (+)NCBI
RefSeq Acc Id: XM_034961464   ⟹   XP_034817355
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2527,372,000 - 27,932,946 (+)NCBI
NHGRI_mPanPan1623,361,923 - 23,917,644 (+)NCBI
Mhudiblu_PPA_v0612,562,958 - 13,118,623 (+)NCBI
RefSeq Acc Id: XM_063605154   ⟹   XP_063461224
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2527,665,463 - 27,944,831 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_024784754   ⟸   XM_024928986
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A156 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034817343   ⟸   XM_034961452
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A156 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034817342   ⟸   XM_034961451
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A156 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034817344   ⟸   XM_034961453
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A156 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034817355   ⟸   XM_034961464
- Peptide Label: isoform X5
- UniProtKB: A0A2R9A156 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034817352   ⟸   XM_034961461
- Peptide Label: isoform X4
- UniProtKB: A0A2R8ZYK9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034817341   ⟸   XM_034961450
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZYK9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000009657   ⟸   ENSPPAT00000032300
RefSeq Acc Id: ENSPPAP00000009652   ⟸   ENSPPAT00000032295
RefSeq Acc Id: ENSPPAP00000009650   ⟸   ENSPPAT00000032293
RefSeq Acc Id: ENSPPAP00000009648   ⟸   ENSPPAT00000032291
RefSeq Acc Id: XP_063461224   ⟸   XM_063605154
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000028050 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000032291.1 UniProtKB/TrEMBL
  ENSPPAT00000032293.1 UniProtKB/TrEMBL
  ENSPPAT00000032295.1 UniProtKB/TrEMBL
  ENSPPAT00000032300.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.1750 UniProtKB/TrEMBL
  6.10.140.2130 UniProtKB/TrEMBL
InterPro RPEL_repeat UniProtKB/TrEMBL
NCBI Gene LOC100979637 ENTREZGENE
PANTHER PHOSPHATASE AND ACTIN REGULATOR PHACTR UniProtKB/TrEMBL
  PTHR12751:SF6 UniProtKB/TrEMBL
Pfam RPEL UniProtKB/TrEMBL
PROSITE RPEL UniProtKB/TrEMBL
SMART RPEL UniProtKB/TrEMBL
UniProt A0A2R8ZXE7_PANPA UniProtKB/TrEMBL
  A0A2R8ZYK9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZYL5_PANPA UniProtKB/TrEMBL
  A0A2R9A156 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-08 PHACTR1  phosphatase and actin regulator 1  LOC100970457  phosphatase and actin regulator 1-like  Data merged from RGD:11936179 737654 PROVISIONAL
2018-05-08 PHACTR1  phosphatase and actin regulator 1  LOC100979637    Symbol and/or name change 5135510 APPROVED