UNK (unk zinc finger) - Rat Genome Database

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Gene: UNK (unk zinc finger) Chlorocebus sabaeus
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Symbol: UNK
Name: unk zinc finger
RGD ID: 18378958
Description: ENCODES a protein that exhibits mRNA CDS binding (ortholog); ribosome binding (ortholog); INVOLVED IN cell morphogenesis involved in neuron differentiation (ortholog); in utero embryonic development (ortholog); negative regulation of cytoplasmic translation (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: RING finger protein unkempt homolog; unkempt family zinc finger
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,858,198 - 45,899,367 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,857,376 - 45,899,313 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,613,886 - 16,656,296 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UNK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,858,198 - 45,899,367 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,857,376 - 45,899,313 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,613,886 - 16,656,296 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
UNK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381775,784,806 - 75,825,799 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1775,784,806 - 75,825,799 (+)EnsemblGRCh38hg38GRCh38
GRCh371773,780,887 - 73,821,880 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,292,276 - 71,333,481 (+)NCBINCBI36Build 36hg18NCBI36
Celera1770,370,731 - 70,411,935 (+)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1769,206,437 - 69,247,636 (+)NCBIHuRef
CHM1_11773,845,995 - 73,886,818 (+)NCBICHM1_1
T2T-CHM13v2.01776,678,053 - 76,718,950 (+)NCBIT2T-CHM13v2.0
Unk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,921,117 - 115,952,040 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,921,148 - 115,952,040 (+)EnsemblGRCm39 Ensembl
GRCm3811116,028,616 - 116,061,214 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,030,322 - 116,061,214 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711115,891,636 - 115,922,508 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,846,412 - 115,877,284 (+)NCBIMGSCv36mm8
Celera11127,792,548 - 127,823,396 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.91NCBI
Unk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810101,764,732 - 101,794,847 (+)NCBIGRCr8
mRatBN7.210101,265,732 - 101,295,950 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,265,703 - 101,295,967 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.010104,582,531 - 104,613,102 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10104,582,955 - 104,612,033 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010103,672,269 - 103,702,612 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,139,489 - 106,169,639 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110106,146,657 - 106,184,153 (+)NCBI
Celera1099,839,358 - 99,869,964 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Unk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,424,638 - 6,470,874 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,424,638 - 6,470,406 (-)NCBIChiLan1.0ChiLan1.0
UNK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21991,828,898 - 91,869,727 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11796,653,617 - 96,694,449 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,735,509 - 69,776,345 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,285,922 - 75,326,427 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,285,922 - 75,326,427 (+)Ensemblpanpan1.1panPan2
UNK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,767,696 - 4,801,324 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,767,743 - 4,801,235 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,447,885 - 5,481,378 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,437,874 - 5,471,691 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,437,874 - 5,471,662 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,477,644 - 5,511,117 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,587,735 - 5,621,211 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,648,419 - 5,682,105 (-)NCBIUU_Cfam_GSD_1.0
Unk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,406,972 - 5,444,552 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936594967,448 - 1,004,966 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936594967,386 - 1,005,085 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,592,503 - 5,628,247 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,592,502 - 5,628,249 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,539,232 - 5,574,622 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Unk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248015,676,521 - 5,719,128 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248015,676,546 - 5,720,483 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 30 20
Low 6 20 40
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000002890   ⟹   ENSCSAP00000001180
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1645,857,376 - 45,899,313 (-)Ensembl
RefSeq Acc Id: XM_008011724   ⟹   XP_008009915
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11645,858,198 - 45,899,317 (-)NCBI
Vero_WHO_p1.0NW_02366607716,613,886 - 16,656,291 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008011725   ⟹   XP_008009916
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11645,858,198 - 45,899,223 (-)NCBI
Vero_WHO_p1.0NW_02366607716,613,886 - 16,656,296 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008011726   ⟹   XP_008009917
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11645,858,198 - 45,899,367 (-)NCBI
Vero_WHO_p1.0NW_02366607716,613,886 - 16,656,291 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037993462   ⟹   XP_037849390
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607716,613,886 - 16,656,261 (-)NCBI
RefSeq Acc Id: XM_037993463   ⟹   XP_037849391
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607716,613,886 - 16,656,210 (-)NCBI
RefSeq Acc Id: XP_008009917   ⟸   XM_008011726
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QXU1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008009915   ⟸   XM_008011724
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008009916   ⟸   XM_008011725
- Peptide Label: isoform X4
RefSeq Acc Id: ENSCSAP00000001180   ⟸   ENSCSAT00000002890
RefSeq Acc Id: XP_037849390   ⟸   XM_037993462
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037849391   ⟸   XM_037993463
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004859 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002890.1 UniProtKB/TrEMBL
Gene3D-CATH Zinc finger, CCCH-type UniProtKB/TrEMBL
InterPro Unkempt-like UniProtKB/TrEMBL
  Unkempt_Znf UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/TrEMBL
  Znf_CCCH_sf UniProtKB/TrEMBL
NCBI Gene UNK ENTREZGENE
PANTHER PTHR14493 UniProtKB/TrEMBL
  RING FINGER PROTEIN UNKEMPT UniProtKB/TrEMBL
Pfam zf-CCCH UniProtKB/TrEMBL
  zf_CCCH_5 UniProtKB/TrEMBL
PROSITE ZF_C3H1 UniProtKB/TrEMBL
SMART ZnF_C3H1 UniProtKB/TrEMBL
Superfamily-SCOP SSF90229 UniProtKB/TrEMBL
UniProt A0A0D9QXU1 ENTREZGENE, UniProtKB/TrEMBL