PRTFDC1 (phosphoribosyl transferase domain containing 1) - Rat Genome Database

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Gene: PRTFDC1 (phosphoribosyl transferase domain containing 1) Chlorocebus sabaeus
Analyze
Symbol: PRTFDC1
Name: phosphoribosyl transferase domain containing 1
RGD ID: 18373601
Description: ENCODES a protein that exhibits hypoxanthine phosphoribosyltransferase activity (ortholog); INVOLVED IN GMP catabolic process (ortholog); guanine salvage (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Mouth Neoplasms (ortholog); Ovarian Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphoribosyltransferase domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1924,568,867 - 24,678,020 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl924,568,692 - 24,677,550 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605130,505,955 - 30,638,727 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
PRTFDC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1924,568,867 - 24,678,020 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl924,568,692 - 24,677,550 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605130,505,955 - 30,638,727 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PRTFDC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381024,848,614 - 24,952,606 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1024,848,614 - 24,952,606 (-)EnsemblGRCh38hg38GRCh38
GRCh371025,137,543 - 25,241,535 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361025,177,560 - 25,281,539 (-)NCBINCBI36Build 36hg18NCBI36
Build 341025,177,559 - 25,281,539NCBI
Celera1024,838,423 - 24,942,409 (-)NCBICelera
Cytogenetic Map10p12.1NCBI
HuRef1024,799,013 - 24,902,637 (-)NCBIHuRef
CHM1_11025,138,118 - 25,242,059 (-)NCBICHM1_1
T2T-CHM13v2.01024,866,903 - 24,970,863 (-)NCBIT2T-CHM13v2.0
Gm13377
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39221,049,620 - 21,144,493 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl221,049,619 - 21,146,765 (-)EnsemblGRCm39 Ensembl
GRCm38221,044,809 - 21,139,682 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl221,044,808 - 21,141,954 (-)EnsemblGRCm38mm10GRCm38
MGSCv37220,966,435 - 21,061,308 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36220,966,435 - 21,061,308 (-)NCBIMGSCv36mm8
Celera220,929,324 - 21,017,413 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map214.73NCBI
Prtfdc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81788,457,872 - 88,563,109 (-)NCBIGRCr8
mRatBN7.21783,549,608 - 83,654,517 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1783,548,803 - 83,655,179 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1787,029,561 - 87,127,894 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01790,864,956 - 90,963,271 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01784,881,888 - 84,980,212 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01787,926,242 - 88,037,040 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1787,927,058 - 88,037,040 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01789,615,538 - 89,724,742 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41795,021,578 - 95,140,362 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11795,031,593 - 95,151,192 (-)NCBI
Celera1782,809,745 - 82,908,068 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
Prtfdc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554294,234,806 - 4,325,896 (+)NCBIChiLan1.0ChiLan1.0
PRTFDC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2837,488,479 - 37,652,082 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11037,531,998 - 37,657,392 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01025,023,015 - 25,127,770 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11025,393,227 - 25,497,054 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1025,393,227 - 25,497,054 (-)Ensemblpanpan1.1panPan2
PRTFDC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.128,551,008 - 8,643,710 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl28,559,319 - 8,642,533 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha27,245,705 - 7,339,234 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.026,750,858 - 6,844,460 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl26,750,953 - 6,844,460 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.126,120,472 - 6,213,933 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.026,197,179 - 6,290,517 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.026,365,431 - 6,458,849 (+)NCBIUU_Cfam_GSD_1.0
Prtfdc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934424,402,890 - 24,485,471 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936484566,543 - 650,896 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936484568,056 - 650,820 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRTFDC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1050,365,587 - 50,461,324 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11050,365,654 - 50,458,487 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21055,787,876 - 55,911,201 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Prtfdc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247964,014,076 - 4,095,920 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20 13 60
Low 16 7
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000010255   ⟹   ENSCSAP00000008352
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl924,568,692 - 24,677,550 (-)Ensembl
RefSeq Acc Id: XM_008002543   ⟹   XP_008000734
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1924,568,867 - 24,677,527 (-)NCBI
Vero_WHO_p1.0NW_02366605130,506,936 - 30,638,240 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008002544   ⟹   XP_008000735
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1924,568,867 - 24,669,903 (-)NCBI
Vero_WHO_p1.0NW_02366605130,506,936 - 30,632,585 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008002545   ⟹   XP_008000736
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1924,568,867 - 24,678,020 (-)NCBI
Vero_WHO_p1.0NW_02366605130,505,955 - 30,638,727 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008000734 (Get FASTA)   NCBI Sequence Viewer  
  XP_008000735 (Get FASTA)   NCBI Sequence Viewer  
  XP_008000736 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008352
  ENSCSAP00000008352.1
RefSeq Acc Id: XP_008000736   ⟸   XM_008002545
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RIB3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008000734   ⟸   XM_008002543
- Peptide Label: isoform X1
RefSeq Acc Id: XP_008000735   ⟸   XM_008002544
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCSAP00000008352   ⟸   ENSCSAT00000010255


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012165 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010255.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.2020 UniProtKB/TrEMBL
InterPro Hxn_phspho_trans UniProtKB/TrEMBL
  PRibTrfase_dom UniProtKB/TrEMBL
  PRTase-like UniProtKB/TrEMBL
NCBI Gene PRTFDC1 ENTREZGENE
PANTHER HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE UniProtKB/TrEMBL
  PHOSPHORIBOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam Pribosyltran UniProtKB/TrEMBL
Superfamily-SCOP SSF53271 UniProtKB/TrEMBL
UniProt A0A0D9RIB3 ENTREZGENE, UniProtKB/TrEMBL