POP5 (POP5 homolog, ribonuclease P/MRP subunit) - Rat Genome Database

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Gene: POP5 (POP5 homolog, ribonuclease P/MRP subunit) Chlorocebus sabaeus
Analyze
Symbol: POP5
Name: POP5 homolog, ribonuclease P/MRP subunit
RGD ID: 18366010
Description: ENCODES a protein that exhibits ribonuclease P activity (ortholog); INVOLVED IN tRNA processing (ortholog); PARTICIPATES IN tRNA maturation pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN multimeric ribonuclease P complex (ortholog); nucleolar ribonuclease P complex (ortholog); ribonuclease MRP complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ribonuclease P/MRP protein subunit POP5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111115,932,265 - 115,934,644 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11115,932,394 - 115,934,562 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037129,162,351 - 129,164,754 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
POP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111115,932,265 - 115,934,644 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11115,932,394 - 115,934,562 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037129,162,351 - 129,164,754 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
POP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812120,578,764 - 120,581,402 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12120,578,764 - 120,581,402 (-)EnsemblGRCh38hg38GRCh38
GRCh3712121,016,567 - 121,019,205 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612119,501,231 - 119,503,584 (-)NCBINCBI36Build 36hg18NCBI36
Celera12120,651,139 - 120,653,492 (-)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12118,026,265 - 118,028,618 (-)NCBIHuRef
CHM1_112120,985,617 - 120,987,970 (-)NCBICHM1_1
T2T-CHM13v2.012120,567,897 - 120,570,535 (-)NCBIT2T-CHM13v2.0
Pop5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395115,373,505 - 115,379,031 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5115,373,895 - 115,383,410 (+)EnsemblGRCm39 Ensembl
GRCm385115,235,588 - 115,240,972 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5115,235,836 - 115,245,351 (+)EnsemblGRCm38mm10GRCm38
MGSCv375115,685,860 - 115,690,981 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365115,496,847 - 115,501,971 (+)NCBIMGSCv36mm8
Celera5112,335,061 - 112,340,187 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map556.01NCBI
Pop5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81247,037,451 - 47,045,778 (-)NCBIGRCr8
mRatBN7.21241,376,755 - 41,384,882 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,376,755 - 41,381,336 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,544,008 - 42,548,590 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,157,673 - 43,162,255 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,218,230 - 42,222,812 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,138,346 - 47,143,152 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,138,346 - 47,142,852 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01248,932,035 - 48,939,948 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,644,912 - 42,649,407 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11242,508,549 - 42,510,469 (-)NCBI
Celera1242,996,403 - 43,001,050 (-)NCBICelera
Cytogenetic Map12q16NCBI
Pop5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545511,069,131 - 11,071,814 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545511,069,131 - 11,071,814 (+)NCBIChiLan1.0ChiLan1.0
POP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210128,649,227 - 128,651,664 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112128,645,602 - 128,648,775 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012118,162,497 - 118,165,472 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112121,535,005 - 121,537,350 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12121,535,005 - 121,537,350 (-)Ensemblpanpan1.1panPan2
POP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12616,463,006 - 16,465,359 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2616,462,994 - 16,465,221 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2616,466,218 - 16,468,556 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02616,729,628 - 16,731,967 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2616,727,535 - 16,731,868 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12616,690,291 - 16,692,628 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02616,765,960 - 16,768,298 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02616,808,032 - 16,810,366 (-)NCBIUU_Cfam_GSD_1.0
Pop5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118145,886,996 - 145,889,799 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936668385,679 - 389,135 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936668385,945 - 388,688 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1440,522,719 - 40,525,866 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11440,523,014 - 40,525,934 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21442,990,859 - 42,993,369 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pop5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474713,088,947 - 13,092,001 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474713,088,928 - 13,092,691 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 36 18 60
Low 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000000262   ⟹   ENSCSAP00000015793
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl11115,932,394 - 115,934,562 (-)Ensembl
RefSeq Acc Id: XM_008004962   ⟹   XP_008003153
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111115,932,265 - 115,934,644 (-)NCBI
Vero_WHO_p1.0NW_023666037129,162,352 - 129,164,754 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004963   ⟹   XP_008003154
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111115,932,265 - 115,934,644 (-)NCBI
Vero_WHO_p1.0NW_023666037129,162,351 - 129,164,754 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008004964   ⟹   XP_008003155
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.111115,932,265 - 115,934,644 (-)NCBI
Vero_WHO_p1.0NW_023666037129,162,352 - 129,164,754 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008003153 (Get FASTA)   NCBI Sequence Viewer  
  XP_008003154 (Get FASTA)   NCBI Sequence Viewer  
  XP_008003155 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015793
  ENSCSAP00000015793.1
Reference Protein Sequences
RefSeq Acc Id: XP_008003155   ⟸   XM_008004964
- Peptide Label: isoform X3
RefSeq Acc Id: XP_008003153   ⟸   XM_008004962
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S4K4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008003154   ⟸   XM_008004963
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000015793   ⟸   ENSCSAT00000000262


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002246 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000262.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.3250 UniProtKB/TrEMBL
InterPro RNase_P/MRP_POP5 UniProtKB/TrEMBL
  RNase_P/MRP_subunit UniProtKB/TrEMBL
  Rnp2-like_sf UniProtKB/TrEMBL
KEGG Report csab:103239262 UniProtKB/TrEMBL
NCBI Gene POP5 ENTREZGENE
PANTHER RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5 UniProtKB/TrEMBL
  RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5 UniProtKB/TrEMBL
Pfam RNase_P_Rpp14 UniProtKB/TrEMBL
PIRSF Ribonuclease_P_prd UniProtKB/TrEMBL
Superfamily-SCOP SSF160350 UniProtKB/TrEMBL
UniProt A0A0D9S4K4 ENTREZGENE, UniProtKB/TrEMBL