DAAM1 (dishevelled associated activator of morphogenesis 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: DAAM1 (dishevelled associated activator of morphogenesis 1) Chlorocebus sabaeus
Analyze
Symbol: DAAM1
Name: dishevelled associated activator of morphogenesis 1
RGD ID: 18348698
Description: ENCODES a protein that exhibits actin binding (inferred); identical protein binding (inferred); small GTPase binding (inferred); INVOLVED IN presynaptic actin cytoskeleton organization (ortholog); PARTICIPATES IN Wnt signaling, non-canonical pathway; Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); intrinsic cardiomyopathy (ortholog); FOUND IN glutamatergic synapse (ortholog); presynapse (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: disheveled-associated activator of morphogenesis 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12436,406,841 - 36,588,993 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2436,406,847 - 36,589,045 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605324,661,222 - 24,842,408 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DAAM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12436,406,841 - 36,588,993 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2436,406,847 - 36,589,045 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605324,661,222 - 24,842,408 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DAAM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381459,188,667 - 59,371,405 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1459,188,646 - 59,371,405 (+)EnsemblGRCh38hg38GRCh38
GRCh371459,655,385 - 59,838,123 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361458,725,152 - 58,906,224 (+)NCBINCBI36Build 36hg18NCBI36
Build 341458,725,151 - 58,906,224NCBI
Celera1439,705,036 - 39,886,100 (+)NCBICelera
Cytogenetic Map14q23.1NCBI
HuRef1439,819,615 - 40,001,983 (+)NCBIHuRef
CHM1_11459,593,312 - 59,776,243 (+)NCBICHM1_1
T2T-CHM13v2.01453,395,543 - 53,578,348 (+)NCBIT2T-CHM13v2.0
Daam1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391271,877,834 - 72,039,150 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1271,877,852 - 72,039,107 (+)EnsemblGRCm39 Ensembl
GRCm381271,830,950 - 71,992,376 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1271,831,078 - 71,992,333 (+)EnsemblGRCm38mm10GRCm38
MGSCv371272,932,065 - 73,093,354 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361272,749,655 - 72,910,944 (+)NCBIMGSCv36mm8
Celera1272,944,641 - 73,102,220 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1230.06NCBI
Daam1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8696,125,521 - 96,286,049 (+)NCBIGRCr8
mRatBN7.2690,389,544 - 90,550,114 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl690,389,688 - 90,550,114 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx690,816,596 - 90,919,779 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0691,116,053 - 91,219,233 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0690,555,621 - 90,658,792 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0694,606,675 - 94,739,026 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl694,636,222 - 94,739,026 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06104,055,469 - 104,183,583 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4694,081,666 - 94,184,202 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1694,081,654 - 94,185,174 (+)NCBI
Celera688,912,980 - 89,016,587 (+)NCBICelera
Cytogenetic Map6q24NCBI
Daam1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546612,954,242 - 13,127,076 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546612,954,557 - 13,129,483 (+)NCBIChiLan1.0ChiLan1.0
DAAM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21560,322,767 - 60,505,772 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11459,539,281 - 59,722,288 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01439,792,952 - 39,975,754 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11458,059,616 - 58,241,353 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1458,133,462 - 58,241,353 (+)Ensemblpanpan1.1panPan2
DAAM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1834,475,045 - 34,641,843 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl834,476,646 - 34,640,231 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha834,235,875 - 34,402,396 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0834,710,887 - 34,877,521 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl834,710,937 - 34,875,420 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1834,328,018 - 34,494,795 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0834,397,374 - 34,563,910 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0834,764,445 - 34,931,060 (+)NCBIUU_Cfam_GSD_1.0
Daam1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864070,431,852 - 70,599,910 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364953,661,284 - 3,759,905 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364953,591,611 - 3,757,646 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DAAM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1188,335,384 - 188,511,096 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11188,335,335 - 188,511,094 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21209,404,401 - 209,532,217 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Daam1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473441,708,570 - 41,866,887 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473441,709,226 - 41,880,149 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 20 54
Low 16 20 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000012423   ⟹   ENSCSAP00000010463
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2436,406,847 - 36,589,045 (+)Ensembl
RefSeq Acc Id: XM_007986820   ⟹   XP_007985011
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12436,406,841 - 36,588,993 (+)NCBI
Vero_WHO_p1.0NW_02366605324,661,222 - 24,842,408 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007986821   ⟹   XP_007985012
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12436,406,841 - 36,588,993 (+)NCBI
Vero_WHO_p1.0NW_02366605324,661,268 - 24,842,408 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007986822   ⟹   XP_007985013
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12436,406,844 - 36,588,993 (+)NCBI
Vero_WHO_p1.0NW_02366605324,661,222 - 24,842,408 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007985011 (Get FASTA)   NCBI Sequence Viewer  
  XP_007985012 (Get FASTA)   NCBI Sequence Viewer  
  XP_007985013 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000010463
  ENSCSAP00000010463.1
Reference Protein Sequences
RefSeq Acc Id: XP_007985012   ⟸   XM_007986821
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RPC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007985011   ⟸   XM_007986820
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RPC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007985013   ⟸   XM_007986822
- Peptide Label: isoform X2
RefSeq Acc Id: ENSCSAP00000010463   ⟸   ENSCSAT00000012423


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000014331 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000012423.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.2220 UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/TrEMBL
  Formin, FH3 diaphanous domain UniProtKB/TrEMBL
  Nucleotidyltransferases domain 2 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  DAD_dom UniProtKB/TrEMBL
  FH2_Formin UniProtKB/TrEMBL
  FH2_Formin_sf UniProtKB/TrEMBL
  FH3_dom UniProtKB/TrEMBL
  GBD/FH3_dom UniProtKB/TrEMBL
  GTPase-bd UniProtKB/TrEMBL
KEGG Report csab:103229096 UniProtKB/TrEMBL
NCBI Gene DAAM1 ENTREZGENE
PANTHER DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1 UniProtKB/TrEMBL
  FORMIN HOMOLOGY 2 FAMILY MEMBER UniProtKB/TrEMBL
Pfam Drf_FH3 UniProtKB/TrEMBL
  Drf_GBD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
PROSITE DAD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
  GBD_FH3 UniProtKB/TrEMBL
SMART Drf_FH3 UniProtKB/TrEMBL
  Drf_GBD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
Superfamily-SCOP Formin homology 2 domain (FH2 domain) UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A0A0D9RPC4 ENTREZGENE, UniProtKB/TrEMBL