Etnppl (ethanolamine phosphate phospholyase)

Gene: Etnppl (ethanolamine phosphate phospholyase) Mus musculus

Analyze

Symbol:

Etnppl

Name:

ethanolamine phosphate phospholyase

RGD ID:

1622275

MGI Page

MGI

Description:

Predicted to enable ethanolamine-phosphate phospho-lyase activity. Predicted to be located in mitochondrion. Orthologous to human ETNPPL (ethanolamine-phosphate phospho-lyase).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

1300019H02Rik; Agxt2; Agxt2l1; AI195447; alanine--glyoxylate aminotransferase 2-like 1; alanine-glyoxylate aminotransferase 2-like 1; ethanolamine-phosphate phospho-lyase

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ETNPPL (ethanolamine-phosphate phospho-lyase)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Etnppl (ethanolamine-phosphate phospho-lyase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Etnppl (ethanolamine-phosphate phospho-lyase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ETNPPL (ethanolamine-phosphate phospho-lyase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ETNPPL (ethanolamine-phosphate phospho-lyase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Etnppl (ethanolamine-phosphate phospho-lyase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ETNPPL (ethanolamine-phosphate phospho-lyase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ETNPPL (ethanolamine-phosphate phospho-lyase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Etnppl (ethanolamine-phosphate phospho-lyase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PHYKPL (5-phosphohydroxy-L-lysine phospho-lyase)	HGNC	OrthoMCL
Alliance orthologs ³
Homo sapiens (human):	ETNPPL (ethanolamine-phosphate phospho-lyase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Etnppl (ethanolamine-phosphate phospho-lyase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	etnppl (ethanolamine-phosphate phospho-lyase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	CG8745	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	eppl-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	etnppl	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	130,411,097 - 130,429,399 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	130,411,097 - 130,431,170 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	130,617,448 - 130,635,750 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	130,617,448 - 130,637,521 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	130,320,366 - 130,338,668 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	130,606,730 - 130,624,903 (+)	NCBI		MGSCv36	mm8
Celera	3	137,132,851 - 137,151,194 (+)	NCBI		Celera
Cytogenetic Map	3	G3	NCBI
cM Map	3	60.47	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-diaminodiphenylmethane (EXP,ISO)

8-Br-cAMP (ISO)

acrylamide (EXP)

aflatoxin B1 (EXP,ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

bromobenzene (ISO)

butanal (ISO)

carbon nanotube (EXP)

CGP 52608 (ISO)

choline (EXP)

copper(II) sulfate (ISO)

Cuprizon (ISO)

cyclosporin A (EXP,ISO)

cyproconazole (EXP)

diclofenac (EXP)

dicrotophos (ISO)

dorsomorphin (ISO)

endosulfan (ISO)

entinostat (ISO)

epoxiconazole (EXP)

ethanol (EXP)

fenthion (EXP)

GW 4064 (EXP)

inulin (EXP)

lipopolysaccharide (EXP)

N-nitrosodiethylamine (EXP)

paracetamol (EXP,ISO)

PCB138 (EXP)

perfluorooctane-1-sulfonic acid (EXP)

phenobarbital (EXP)

pirinixic acid (EXP,ISO)

pregnenolone 16alpha-carbonitrile (EXP)

propiconazole (EXP)

quercetin (ISO)

quinolin-8-ol (ISO)

rifampicin (ISO)

SB 431542 (ISO)

senecionine (EXP)

sodium arsenite (EXP,ISO)

sulforaphane (ISO)

sulindac sulfide (ISO)

tetrachloromethane (EXP)

thioacetamide (ISO)

titanium dioxide (EXP)

trichostatin A (ISO)

troglitazone (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

Cellular Component

mitochondrion (IEA)

Molecular Function

ethanolamine-phosphate phospho-lyase activity (IBA,ISO)

lyase activity (IEA)

molecular_function (ND)

pyridoxal phosphate binding (IEA)

transaminase activity (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal phospholipid level (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:14681479	PMID:16141072	PMID:16141073	PMID:21267068	PMID:21677750
PMID:21873635	PMID:34048714	PMID:36794261

Genomics

Comparative Map Data

Etnppl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	130,411,097 - 130,429,399 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	130,411,097 - 130,431,170 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	130,617,448 - 130,635,750 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	130,617,448 - 130,637,521 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	130,320,366 - 130,338,668 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	130,606,730 - 130,624,903 (+)	NCBI		MGSCv36	mm8
Celera	3	137,132,851 - 137,151,194 (+)	NCBI		Celera
Cytogenetic Map	3	G3	NCBI
cM Map	3	60.47	NCBI

ETNPPL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	108,742,053 - 108,763,053 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	108,742,048 - 108,763,054 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	109,663,209 - 109,684,209 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	109,882,645 - 109,903,658 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	110,020,807 - 110,041,813	NCBI
Celera	4	106,958,027 - 106,978,961 (-)	NCBI		Celera
Cytogenetic Map	4	q25	NCBI
HuRef	4	105,395,013 - 105,416,012 (-)	NCBI		HuRef
CHM1_1	4	109,639,905 - 109,660,851 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	112,045,047 - 112,066,004 (-)	NCBI		T2T-CHM13v2.0

Etnppl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	221,847,210 - 221,868,827 (+)	NCBI		GRCr8
mRatBN7.2	2	219,173,048 - 219,194,646 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	219,172,978 - 219,192,212 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	2	235,738,377 - 235,760,351 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	235,738,416 - 235,760,352 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	254,289,706 - 254,309,474 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	2	211,440,271 - 211,459,741 (+)	NCBI		Celera
Cytogenetic Map	2	q43	NCBI

Etnppl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955496	1,275,051 - 1,292,349 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955496	1,274,929 - 1,292,802 (+)	NCBI	ChiLan1.0	ChiLan1.0

ETNPPL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	106,838,230 - 106,859,275 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	107,133,189 - 107,154,245 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	101,244,460 - 101,265,672 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	111,815,214 - 111,836,412 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	111,815,226 - 111,836,412 (-)	Ensembl	panpan1.1		panPan2

ETNPPL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	29,073,846 - 29,093,077 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	28,963,168 - 29,093,101 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	12,927,060 - 12,947,164 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	29,302,397 - 29,322,276 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	29,302,405 - 29,321,527 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	29,296,692 - 29,316,808 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	29,041,213 - 29,060,278 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	10,794,955 - 10,814,884 (+)	NCBI		UU_Cfam_GSD_1.0

Etnppl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405301	11,876,410 - 11,894,779 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936563	56,776 - 74,403 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936563	56,216 - 74,591 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ETNPPL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	113,363,042 - 113,384,774 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	113,363,047 - 113,384,783 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	121,603,071 - 121,622,426 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ETNPPL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	56,670,688 - 56,692,069 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	56,669,718 - 56,691,026 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	35,296,344 - 35,316,825 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Etnppl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624830	924,185 - 938,388 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624830	923,034 - 938,773 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Etnppl
680 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	509
Count of miRNA genes:	334
Interacting mature miRNAs:	381
Transcripts:	ENSMUST00000072271, ENSMUST00000163620, ENSMUST00000166187, ENSMUST00000170664, ENSMUST00000172432
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
26884436	Zlq3_m	zygomatic length QTL 3, 10 week (mouse)					3	3265060	142405761	Mouse
1302056	Orgwq4_m	organ weight QTL 4 (mouse)			Not determined		3	30067588	147304689	Mouse
1301705	Sles3_m	systemic lupus erythmatosus suppressor 3 (mouse)			Not determined		3	37174862	143353183	Mouse
26884382	Bzwq1_m	bi-zygomatic width QTL 1, 5 week (mouse)					3	52207421	137205761	Mouse
4142178	Ctrq2_m	C. trachomatis resistance QTL 2 (mouse)			Not determined		3	89139967	137453008	Mouse
27226732	Tibmd3_m	tibia midshaft diameter 3, 10 week (mouse)					3	96607316	147805636	Mouse
10043955	Wt10q4_m	body weight, 10 weeks, QTL 4 (mouse)			Not determined		3	98624041	132624197	Mouse
11533920	Mvb3_m	modifier of vibrator 3 (mouse)					3	98635284	132635383	Mouse
12792984	Modn1_m	modifier of Dstn neovascularization 1 (mouse)					3	98635284	132635383	Mouse
1302114	Tbs1_m	tuberculosis severity 1 (mouse)			Not determined		3	98924105	132924250	Mouse
1300752	Ap6q_m	alcohol preference 6 QTL (mouse)			Not determined		3	100372912	147045722	Mouse
26884419	Bzwq6_m	bi-zygomatic width QTL 6, 10 week (mouse)					3	100607316	137205761	Mouse
27226733	Tibmd6_m	tibia midshaft diameter 6, 16 week (mouse)					3	101307316	149805637	Mouse
1301805	Mors2_m	modifier of obesity related sterility 2 (mouse)			Not determined		3	103482659	137482783	Mouse
1302093	Orgwq5_m	organ weight QTL 5 (mouse)			Not determined		3	107376936	147304689	Mouse
1300619	Cdcs1_m	cytokine deficiency colitis susceptibility 1 (mouse)			Not determined		3	109834882	143835005	Mouse
12910793	Pwbwq7_m	post-weaning body weight QTL 7 (mouse)					3	110084357	135715812	Mouse
12910796	Pwbwq6_m	post-weaning body weight QTL 6 (mouse)					3	110084357	135715812	Mouse
12910815	Ogrq1_m	overall growth rate QTL 1 (mouse)					3	110084357	135715812	Mouse
1301381	Bomb1_m	bone marrow pre-B 1 (mouse)			Not determined		3	111133243	145133417	Mouse
1301100	Bdt2_m	bone density traits 2 (mouse)			Not determined		3	114736617	148736784	Mouse
10043919	Afpq8_m	abdominal fat percent QTL 8 (mouse)			Not determined		3	119057332	153057456	Mouse
1558868	Ses9_m	salmonella enteritidis susceptibility 9 (mouse)			Not determined		3	119057332	153057456	Mouse
4141935	Tgq15_m	triglyceride QTL 15 (mouse)			Not determined			119318586	153318586	Mouse
4142449	Tgq14_m	triglyceride QTL 14 (mouse)			Not determined			119318586	153318586	Mouse
1302151	Lprm2_m	lymphoproliferation modifier 2 (mouse)			Not determined		3	119778857	153779044	Mouse
10412240	Alpq6_m	alcohol preference QTL 6 (mouse)			Not determined		3	120772078	154772078	Mouse
26884415	Bzwq11_m	bi-zygomatic width QTL 11, 16 week (mouse)					3	124993649	137205761	Mouse
4142245	Pstc1_m	periosteal circumference 1 (mouse)			Not determined		3	126270248	159745316	Mouse
1301218	Letohc1_m	low ethanol consumption 1 (mouse)			Not determined		3	126352986	159745316	Mouse
1301347	Fpli_m	fasting plasma insulin (mouse)			Not determined		3	126460514	159745316	Mouse

Markers in Region

AI195447

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	3	130,635,240 - 130,635,464	UniSTS	GRCm38
MGSCv37	3	130,338,158 - 130,338,382	UniSTS	GRCm37
Celera	3	137,150,684 - 137,150,908	UniSTS
Cytogenetic Map	3	G3	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001163587	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_027907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC110540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK005060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK030395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK049937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC022644	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC043680	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC058592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000072271 ⟹ ENSMUSP00000072121

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	130,411,218 - 130,431,170 (+)	Ensembl
GRCm38.p6 Ensembl	3	130,617,569 - 130,637,521 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000163620 ⟹ ENSMUSP00000129120

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	130,411,342 - 130,428,326 (+)	Ensembl
GRCm38.p6 Ensembl	3	130,617,693 - 130,634,677 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000166187 ⟹ ENSMUSP00000131294

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	130,411,097 - 130,428,458 (+)	Ensembl
GRCm38.p6 Ensembl	3	130,617,448 - 130,634,809 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000170664 ⟹ ENSMUSP00000128425

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	130,420,169 - 130,423,373 (+)	Ensembl
GRCm38.p6 Ensembl	3	130,626,520 - 130,629,724 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000172432

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	130,411,248 - 130,415,299 (+)	Ensembl
GRCm38.p6 Ensembl	3	130,617,599 - 130,621,650 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000199940

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	130,411,221 - 130,415,277 (+)	Ensembl
GRCm38.p6 Ensembl	3	130,617,572 - 130,621,628 (+)	Ensembl

RefSeq Acc Id:

NM_001163587 ⟹ NP_001157059

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	3	130,411,097 - 130,429,399 (+)	NCBI
GRCm38	3	130,617,448 - 130,635,750 (+)	ENTREZGENE
MGSCv37	3	130,320,366 - 130,338,668 (+)	RGD
Celera	3	137,132,851 - 137,151,194 (+)	RGD
cM Map	3		ENTREZGENE

Sequence:

show sequence

GGCGGAGGTGGCCTGGCTGCTGACTTGCGTCCCAGGTTACAGAGGGAGGAACATTCATTGACTT
GAAGGGTGCAGCGGTCATGTGCGAGCTCTATAGCAAGCAGGACACCCTGGCGCTGAGGGAGAGG
CACATCGGGCCCTCGTGCAAAATTTTCTTTGCCGCGGATCCCATCAAAATAATGCGAGCCCAGG
GGCAGTACATGTTTGATGAGAAAGGCGAACGGTACTTAGACTGCATCAACAACGTGGCGCATGT
GGGACACTGTCACCCAGAAGTGGTCAAAGCTGCCGCGAAACAGATGGAATTACTAAATACAAAT
TCTCGCTTCCTCCACGACAACATCATTGAGTTTGCCAAGCGCCTTACTGCCACCCTGCCTCAGG
AGCTCTCCGTTTGCTACTTCACAAACTCCGGATCCGAAGCCAATGACTTAGCCTTACGTCTGGC
ACGGCAGTTCCGAGGCCACCAGGATGTGATCACCCTTGACCATGCTTACCACGGCCACCTGTCG
TCATTAATTGAGATCAGTCCTTATAAGTTTCAGAAGGGCAAAGATGTCAAGAGGGAAACTGTAC
ATGTGGCACCAGCTCCAGACACTTACAGAGGGAAATACAGAGAGGACCACGAAGACCCATCCAC
TGCATATGCCGACGAGGTGAAGAAGATCATTGAAGAGGCTCACAGCAGCGGAAGGAAGATTGCT
GCCTTTATTGCTGAATCCATGCAGAGTTGTGGTGGACAAATTATTCCTCCAGCAGGCTACTTCC
AGAAAGTGGCTGAACACATTCACAAAGCAGGAGGTGTGTTCATTGCTGACGAAGTTCAAGTAGG
CTTTGGCAGAGTTGGGAGGTACTTCTGGAGCTTCCAGATGTATGGTGAAGACTTCGTTCCAGAC
ATCGTCACCATGGGGAAACCTATGGGCAACGGTCACCCGATATCCTGTGTGGTGACAACCAAAG
AAATTGCAGAAGCCTTCAGCAGCTCGGGCATGGAATATTTCAATACGTATGGAGGAAATCCAGT
GTCTTGTGCAGTTGGCTTGGCTGTGCTGGATGTAATTGAAAAGGAGAACCTTCAAGGGAATGCT
GTCAGAGTGGGGACCTATCTCATGGAGCTGCTGAGTGAACAGAAGGCTAAGCATCCCTTGATAG
GGGACATCAGAGGTGTCGGCCTTTTTATCGGCATCGATTTGGTGAAGGACCGTGAGAAAAGAAC
ACCTGCGACAGCTGAAGCACAGCACATCATCTACGAGATGAAAGGAAAGGGGGTACTTCTCAGT
GCCGATGGCCCTCACAGGAACGTGCTGAAAATAAAACCACCCATGTGCTTCACGGAAGACGATG
CAAAGTTCCTGGTGGACCACCTTGACGGCATTTTAACAGTTTTAGAAGAAGCCATGGACTCCAA
GAGTGGAACTGTGTTCTCTGAGAACACAGCTTACAGAACAAAGATGCCTAAGGAAATACAAGTG
GAATTGCCCAACCTTAGTGCCACCGAGGCCAGAGAAATCCCCAGGGGAAAGAGAAATGGTGTAT
GCTCAGACCAGCAAGCCCTGCTCAGCAAAAGACTCAAGACATGAGAGCTGAGTGCTAAACAGTG
GATAAATATCCAGGAACACAGTGTGCAAGTGGATGCATCTCATCTCTTAGTGATCCTTTAAATT
GCAATTTTCAATCTGTCTAACTTGTACATTAAAAGATAGATTAATAATATCAATGATCAAAGTG
ATAAACTATGTCAACATTATTGATTGAGCCTCTTGTCTGATAATTCATTGCCTGTAATTCTAAA
GTTATTTATTCTACTAAAACTGAGTTTTCCTTTGCAAGACTAAGCTGGGTGCCTTGCTTCTCAC
ATTGCCATGTTTGAAATTAGAGAAAAAGTGAAGTCTATTTCTTCACGTCAGAGAGTTAGTATAC
TGAAGTATTTTTAATCACAAGAAATGCTCTAAAACGGTTGATATAAAAACTTTATTTCTAGATT
TTAATAAAATAAAAGACGATCTAACAAAAATGAAGACTATAAAATGTAGAGAGCTCTGTAGGTT
ATGGTGGTGAAATCTAAATCGTTCTGAAAGGAAATCACAGAGCTGAGAGGAAAATGGCAAAGAA
GAGCGGTTGGTAAGAAACCTGGTTATTTGCCATGTTGTGGGAACTGGAAGGGAACACATACACA
GAGACCCTTGCGTGAGGAAGTTCCTAGAGTGACAGAAGCAGCCAAAGCCCAGCATTCAGGGTTG
GGGACTTTGATTCTGGCTACTCACAGGCTATGCCACCTTGACCAAGTTGCTCACCTATCAGGTA
AAAATGGCCCCTCCTCCGAACACCTTATTTTCCCCAACTTCATTATCACCTGCATCCCACTGTC
CTAAATTACCTTCGTCTGACCTGTATCTCTCTATTGCCTTCCTACTAGTTATTAAACTTGCTGG
TTTGTTTTTATTCCGTAAAGAAGAGACAGCAACTTTTCTATGCCTGTTTACTGTTAACTGAGTG
AGATGTCTCCTTTGGAGTATGAGCCTGTTCTTTGGATAATGGTAATTCAGGGAACTTCTTGTCT
GTGGTTAACACATGTGGAAAGCCTTGGATTGTGGTCCTGAAAGTCTGTTCAAAAGACAAAAAAA
ATAAAAAAATAAAAACAAGGCAAACTGAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_027907 ⟹ NP_082183

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	3	130,411,224 - 130,429,399 (+)	NCBI
GRCm38	3	130,617,575 - 130,635,750 (+)	NCBI
MGSCv37	3	130,320,366 - 130,338,668 (+)	RGD
Celera	3	137,132,851 - 137,151,194 (+)	RGD
cM Map	3		ENTREZGENE

Sequence:

show sequence

GCCACTAGTGACCTCCGATACCCAGGGCAGGAGGCACAGGAGGGGAGAAAAAAAATCCTTTGCA
GCGTCCCAGGTTACAGAGGGAGGAACATTCATTGACTTGAAGGGTGCAGCGGTCATGTGCGAGC
TCTATAGCAAGCAGGACACCCTGGCGCTGAGGGAGAGGCACATCGGGCCCTCGTGCAAAATTTT
CTTTGCCGCGGATCCCATCAAAATAATGCGAGCCCAGGGGCAGTACATGTTTGATGAGAAAGGC
GAACGGTACTTAGACTGCATCAACAACGTGGCGCATGTGGGACACTGTCACCCAGAAGTGGTCA
AAGCTGCCGCGAAACAGATGGAATTACTAAATACAAATTCTCGCTTCCTCCACGACAACATCAT
TGAGTTTGCCAAGCGCCTTACTGCCACCCTGCCTCAGGAGCTCTCCGTTTGCTACTTCACAAAC
TCCGGATCCGAAGCCAATGACTTAGCCTTACGTCTGGCACGGCAGTTCCGAGGCCACCAGGATG
TGATCACCCTTGACCATGCTTACCACGGCCACCTGTCGTCATTAATTGAGATCAGTCCTTATAA
GTTTCAGAAGGGCAAAGATGTCAAGAGGGAAACTGTACATGTGGCACCAGCTCCAGACACTTAC
AGAGGGAAATACAGAGAGGACCACGAAGACCCATCCACTGCATATGCCGACGAGGTGAAGAAGA
TCATTGAAGAGGCTCACAGCAGCGGAAGGAAGATTGCTGCCTTTATTGCTGAATCCATGCAGAG
TTGTGGTGGACAAATTATTCCTCCAGCAGGCTACTTCCAGAAAGTGGCTGAACACATTCACAAA
GCAGGAGGTGTGTTCATTGCTGACGAAGTTCAAGTAGGCTTTGGCAGAGTTGGGAGGTACTTCT
GGAGCTTCCAGATGTATGGTGAAGACTTCGTTCCAGACATCGTCACCATGGGGAAACCTATGGG
CAACGGTCACCCGATATCCTGTGTGGTGACAACCAAAGAAATTGCAGAAGCCTTCAGCAGCTCG
GGCATGGAATATTTCAATACGTATGGAGGAAATCCAGTGTCTTGTGCAGTTGGCTTGGCTGTGC
TGGATGTAATTGAAAAGGAGAACCTTCAAGGGAATGCTGTCAGAGTGGGGACCTATCTCATGGA
GCTGCTGAGTGAACAGAAGGCTAAGCATCCCTTGATAGGGGACATCAGAGGTGTCGGCCTTTTT
ATCGGCATCGATTTGGTGAAGGACCGTGAGAAAAGAACACCTGCGACAGCTGAAGCACAGCACA
TCATCTACGAGATGAAAGGAAAGGGGGTACTTCTCAGTGCCGATGGCCCTCACAGGAACGTGCT
GAAAATAAAACCACCCATGTGCTTCACGGAAGACGATGCAAAGTTCCTGGTGGACCACCTTGAC
GGCATTTTAACAGTTTTAGAAGAAGCCATGGACTCCAAGAGTGGAACTGTGTTCTCTGAGAACA
CAGCTTACAGAACAAAGATGCCTAAGGAAATACAAGTGGAATTGCCCAACCTTAGTGCCACCGA
GGCCAGAGAAATCCCCAGGGGAAAGAGAAATGGTGTATGCTCAGACCAGCAAGCCCTGCTCAGC
AAAAGACTCAAGACATGAGAGCTGAGTGCTAAACAGTGGATAAATATCCAGGAACACAGTGTGC
AAGTGGATGCATCTCATCTCTTAGTGATCCTTTAAATTGCAATTTTCAATCTGTCTAACTTGTA
CATTAAAAGATAGATTAATAATATCAATGATCAAAGTGATAAACTATGTCAACATTATTGATTG
AGCCTCTTGTCTGATAATTCATTGCCTGTAATTCTAAAGTTATTTATTCTACTAAAACTGAGTT
TTCCTTTGCAAGACTAAGCTGGGTGCCTTGCTTCTCACATTGCCATGTTTGAAATTAGAGAAAA
AGTGAAGTCTATTTCTTCACGTCAGAGAGTTAGTATACTGAAGTATTTTTAATCACAAGAAATG
CTCTAAAACGGTTGATATAAAAACTTTATTTCTAGATTTTAATAAAATAAAAGACGATCTAACA
AAAATGAAGACTATAAAATGTAGAGAGCTCTGTAGGTTATGGTGGTGAAATCTAAATCGTTCTG
AAAGGAAATCACAGAGCTGAGAGGAAAATGGCAAAGAAGAGCGGTTGGTAAGAAACCTGGTTAT
TTGCCATGTTGTGGGAACTGGAAGGGAACACATACACAGAGACCCTTGCGTGAGGAAGTTCCTA
GAGTGACAGAAGCAGCCAAAGCCCAGCATTCAGGGTTGGGGACTTTGATTCTGGCTACTCACAG
GCTATGCCACCTTGACCAAGTTGCTCACCTATCAGGTAAAAATGGCCCCTCCTCCGAACACCTT
ATTTTCCCCAACTTCATTATCACCTGCATCCCACTGTCCTAAATTACCTTCGTCTGACCTGTAT
CTCTCTATTGCCTTCCTACTAGTTATTAAACTTGCTGGTTTGTTTTTATTCCGTAAAGAAGAGA
CAGCAACTTTTCTATGCCTGTTTACTGTTAACTGAGTGAGATGTCTCCTTTGGAGTATGAGCCT
GTTCTTTGGATAATGGTAATTCAGGGAACTTCTTGTCTGTGGTTAACACATGTGGAAAGCCTTG
GATTGTGGTCCTGAAAGTCTGTTCAAAAGACAAAAAAAATAAAAAAATAAAAACAAGGCAAACT
GAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001157059	(Get FASTA)	NCBI Sequence Viewer
	NP_082183	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH43680	(Get FASTA)	NCBI Sequence Viewer
	AAH58592	(Get FASTA)	NCBI Sequence Viewer
	BAB23784	(Get FASTA)	NCBI Sequence Viewer
	BAC33993	(Get FASTA)	NCBI Sequence Viewer
	EDL12214	(Get FASTA)	NCBI Sequence Viewer
	EDL12215	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000072121
	ENSMUSP00000072121.7
	ENSMUSP00000128425.2
	ENSMUSP00000129120.2
	ENSMUSP00000131294
	ENSMUSP00000131294.2
GenBank Protein	Q8BWU8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_082183 ⟸ NM_027907

- UniProtKB:

Q811K4 (UniProtKB/Swiss-Prot), Q9DBB3 (UniProtKB/Swiss-Prot), Q8BWU8 (UniProtKB/Swiss-Prot), E9PYH3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MCELYSKQDTLALRERHIGPSCKIFFAADPIKIMRAQGQYMFDEKGERYLDCINNVAHVGHCHP
EVVKAAAKQMELLNTNSRFLHDNIIEFAKRLTATLPQELSVCYFTNSGSEANDLALRLARQFRG
HQDVITLDHAYHGHLSSLIEISPYKFQKGKDVKRETVHVAPAPDTYRGKYREDHEDPSTAYADE
VKKIIEEAHSSGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEHIHKAGGVFIADEVQVGFGRVG
RYFWSFQMYGEDFVPDIVTMGKPMGNGHPISCVVTTKEIAEAFSSSGMEYFNTYGGNPVSCAVG
LAVLDVIEKENLQGNAVRVGTYLMELLSEQKAKHPLIGDIRGVGLFIGIDLVKDREKRTPATAE
AQHIIYEMKGKGVLLSADGPHRNVLKIKPPMCFTEDDAKFLVDHLDGILTVLEEAMDSKSGTVF
SENTAYRTKMPKEIQVELPNLSATEAREIPRGKRNGVCSDQQALLSKRLKT

hide sequence

RefSeq Acc Id:

NP_001157059 ⟸ NM_001163587

- UniProtKB:

Q811K4 (UniProtKB/Swiss-Prot), Q9DBB3 (UniProtKB/Swiss-Prot), Q8BWU8 (UniProtKB/Swiss-Prot), E9PYH3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MCELYSKQDTLALRERHIGPSCKIFFAADPIKIMRAQGQYMFDEKGERYLDCINNVAHVGHCHP
EVVKAAAKQMELLNTNSRFLHDNIIEFAKRLTATLPQELSVCYFTNSGSEANDLALRLARQFRG
HQDVITLDHAYHGHLSSLIEISPYKFQKGKDVKRETVHVAPAPDTYRGKYREDHEDPSTAYADE
VKKIIEEAHSSGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEHIHKAGGVFIADEVQVGFGRVG
RYFWSFQMYGEDFVPDIVTMGKPMGNGHPISCVVTTKEIAEAFSSSGMEYFNTYGGNPVSCAVG
LAVLDVIEKENLQGNAVRVGTYLMELLSEQKAKHPLIGDIRGVGLFIGIDLVKDREKRTPATAE
AQHIIYEMKGKGVLLSADGPHRNVLKIKPPMCFTEDDAKFLVDHLDGILTVLEEAMDSKSGTVF
SENTAYRTKMPKEIQVELPNLSATEAREIPRGKRNGVCSDQQALLSKRLKT

hide sequence

RefSeq Acc Id:

ENSMUSP00000129120 ⟸ ENSMUST00000163620

RefSeq Acc Id:

ENSMUSP00000131294 ⟸ ENSMUST00000166187

RefSeq Acc Id:

ENSMUSP00000128425 ⟸ ENSMUST00000170664

RefSeq Acc Id:

ENSMUSP00000072121 ⟸ ENSMUST00000072271

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8BWU8-F1-model_v2	AlphaFold	Q8BWU8	1-499	view protein structure

Promoters

RGD ID:

6833362

Promoter ID:

MM_KWN:36100

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Liver

Transcripts:

NM_001163587, NM_027907, UC008RJA.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	3	130,320,306 - 130,320,806 (+)	MPROMDB

RGD ID:

6882372

Promoter ID:

EPDNEW_M4637

Type:

single initiation site

Name:

Etnppl_1

Description:

Mus musculus ethanolamine phosphate phospholyase , transcriptvariant 1, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	3	130,617,573 - 130,617,633	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1919010	AgrOrtholog
Ensembl Genes	ENSMUSG00000019232	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000072271	ENTREZGENE
	ENSMUST00000072271.13	UniProtKB/Swiss-Prot
	ENSMUST00000163620.8	UniProtKB/TrEMBL
	ENSMUST00000166187	ENTREZGENE
	ENSMUST00000166187.8	UniProtKB/Swiss-Prot
	ENSMUST00000170664.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.640.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.90.1150.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Aminotrans_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Aminotrans_3_PPA_site	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase_dom1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PyrdxlP-dep_Trfase_major	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:71760	UniProtKB/Swiss-Prot
MGD	MGI:1919010	ENTREZGENE
NCBI Gene	71760	ENTREZGENE
PANTHER	ETHANOLAMINE-PHOSPHATE PHOSPHO-LYASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR45688	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Aminotran_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Etnppl	PhenoGen
PIRSF	Transaminase_4ab_Lys_Orn	UniProtKB/Swiss-Prot
PROSITE	AA_TRANSFER_CLASS_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF53383	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	AT2L1_MOUSE	UniProtKB/Swiss-Prot
	E9PYH3	ENTREZGENE, UniProtKB/TrEMBL
	F7AY26_MOUSE	UniProtKB/TrEMBL
	Q811K4	ENTREZGENE
	Q8BWU8	ENTREZGENE
	Q9DBB3	ENTREZGENE
UniProt Secondary	Q811K4	UniProtKB/Swiss-Prot
	Q9DBB3	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-07-02	Etnppl	ethanolamine phosphate phospholyase	Agxt2l1	alanine-glyoxylate aminotransferase 2-like 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Mammalian Phenotype